Building trust is essential for successful teams in the pharmaceutical industry. Trust requires conscious effort to build and is an ongoing process. Teams benefit from diversity of skills among members, and managers should recognize these differences. Managers can build trust by challenging routines, recognizing efforts, allowing expectations to be discussed, and frequent communication that shows care for team members personally. Simple low-cost ways to motivate teams include opportunities to contribute, positive recognition, respect among all levels, avoiding rigidity, and understanding individual interests.