Boletín de novedades en el sector de la Nanomedicina

1. Febrero 2011
Boletín
Nanomedicina
generado por VIGIALE, IALE Tecnología.

2. HIDDEN TEXT TO MARK THE BEGINNING OF THE TABLE OF CONTENTS
INDICE
NOTICIAS
1. Gene fuelled transporter causes breast cancer cells to self-destruct 2
2. Nanoparticles that mimic viruses can stimulate long lasting immunity 2
3. Fingerprints of a gold cluster revealed 2
4. Virus-Mimicking nanoparticles can stimulate long-lasting immunity 2
5. Clues to mystery of preterm delivery 3
6. Tuning the collective properties of artificial nanoparticle supercrystals 3
7. NanoBioConnect: A new tool to accelerate commercialization of nanobiotechnology 3
8. Prótesis articulares más seguras 3
9. Engineered cells could usher in programmable cell therapies 3
10. Modified RNA creates stable therapeutic nanoparticles 4
11. Enabling nanoparticles to penetrate deeply in tumors 4
12. MIT engineers design new nanoparticle that could lead to vaccines 4
13. Simpler way of making proteins could lead to new nanomedicine agents 4
14. New technology in human trials to spot cardiac disease 5
15. Desarrollan un sistema de transporte de fármacos antitumorales 5
16. Magnetic nanoparticles could track transplanted neural stem cells following spinal injury 5
17. Tiny 'microworms' could be implanted under the skin for continuous medical monitoring 5
18. Fresh technology for new cell creation 5
19. Unos nanotransportadores consiguen pasar 6
20. Next-Generation sensor technology to be developed by Optiqua-NTU Partnership 6
21. Tracking neural stem cells 6
22. Circulating tumor cell detection may be enhanced by nanoparticles 6
23. Drug encapsulation and gene therapies use new data obtained on liposomes 7
24. Precise new sensor employs hydrogels 7
PATENTES
25. Patentes publicadas este mes 7
26. Origen de los principales actores del mes 8
27. Principales titulares de las patentes del mes 8
28. Principales temas tratados en las patentes del mes 9
29. Principales inventores que patentaron este mes 9
30. US20110033522A1: Reagents for inducing an immune response 10
31. US20110038939A1: Therapeutic stable nanoparticles 10
32. US20110033550A1: Nanoparticle carriers for drug administration 10
33. US20110044893A1: Vascular targets for detecting, imaging and treating .. 10
34. US20110027174A1: Nanotubes for cancer therapy and diagnostics 10

3. INDICE
35. WO2011019211A2: Silk nanofiber nerve conduit and method for producing thereof 11
36. WO2011017456A2: Localized delivery of nanoparticles for therapeutic and diagnostic applications 11
37. US20110045031A1: Use of buckysome or carbon nanotube for drug delivery 11
38. US20110045055A1: Medical devices containing therapeutic agents 12
39. DK0912734T3: Chimeric heteromultimer adhesins 12
40. WO2011017313A1: Method of administering non-viral nucleic acid vectors to the eye 12
41. WO2011017442A2: Anti-RSV immunogens and methods of immunization 12
42. WO2011017690A2: Intracellular delivery of contrast agents with functionalized nanoparticles 13
43. US20110038905A1: Skin anti-aging agent for external use 13
44. US20110034916A1: Nanoparticle-mediated microwave treatment methods 13
45. WO2011012867A1: A delivery system comprising a silicon-containing material 13
46. US20110033419A1: Methods and compositions for treating cancer 14
47. WO2011012721A1: Carrier linked pramipexole prodrugs 14
48. WO2011014562A1: Methods and devices for targeted injection of microspheres 14
49. WO2011019954A2: Intracochlear drug delivery to the central nervous system 14
50. US20110038900A1: Nanoparticles for use in pharmaceutical compositions 15
EVENTOS, CURSOS Y
SEMINARIOS
51. Concertation des nanorevetements (stakeholder dialogue on nanocoatings) 15
52. INRS Occupational Health Research Conference 2011 15
53. IV Conferencia Anual de las Plataformas Tecnológicas de Investigación Biomédica 15
54. Nanotubes and Nanocomposites 2011 16
55. ImagineNano 16
56. COIN Hosts Nanomedicine Commercialization Workshop 16
57. NanoManufacturing Conference & Exhibits 16
58. 2nd NanoDiaRA Seminar 16
59. Conference Innovation in Healthcare: from Research to Market 17
60. 5th Concertation and Consultation Workshop on Micro-Nano-Bio convergence Systems 17
61. Latin American Biomedical Nanotechnology Showcase 17
62. Seminar on Micro- and Nanotechnology Based Tools for Early Detection of Diseases 17
63. MicroMaterials Nanomechanical Testing Technical Seminar 18
64. Nanotechnologies et risques: responsabilités et assurances? 18
ARTÍCULOS-
CIENTÍFICOS
65. Principales investigadores que publicaron este mes 18

4. INDICE
66. Principales entidades con publicaciones este mes 19
67. Principales temas tratados en los artículos científicos del mes 19
68. "Off-On" Electrochemical Hairpin-DNA-Based Genosensor 20
69. Biostability of y-Fe2O3 nano particles 20
70. Size and surface charge of gold nanoparticles.. 20
71. Problems and challenges in the development and validation of human cell-based assays.. 20
72. Solid lipid nanoparticles reduce systemic toxicity of docetaxel 20
73. Cellular response of RAW 264.7 to spray-coated multi-walled carbon nanotube films 21
74. Analysis of Amyloid-b; Peptides in cerebrospinal fluid samples by capillary electrophoresis 21
75. Human skin penetration of gold nanoparticles through intact and damaged skin 21
76. Hazard identification of particulate matter on vasomotor dysfunction and atherosclerosis 21
77. Contribution of nano-copper particles to in vivo liver dysfunction and cellular damage 22
78. Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions 22
79. An effective strategy for the synthesis of biocompatible gold nanoparticles 22
80. Spherical bioactive glass particles and their interaction with human mesenchymal stem cells 22
81. Human skin penetration of gold nanoparticles through intact and damaged skin 23
REPORTES, LIBROS,
OTRAS
PUBLICACIONES
82. Nanotoxicology: An Interdisciplinary Challenge 23
83. Nanotechnology in Medicine - Pharma-Reports 23
84. La nanotecnología española se coloca a la vanguardia internacional del sector 23
85. Drug Regulation in the Modern Era 24
86. Nanotechnology in Drug Delivery - Technological Improvements and Novel Approaches 24
87. Biochips - Products, Applications, Technologies and End-use Markets Growth Analysis 24
88. Nanomedicines in Argentina 2011 24

5. Nanomedicina
NOTICIAS
Gene fuelled transporter causes breast cancer cells to self-destruct
Publicada en Nanomedicine Research - News, 02/28/2011.
Scientists at Queen's University Belfast have shown that they can deliver a gene directly into breast cancer cells
causing them to self-destruct, using an innovative, miniscule gene transport system, according to research published
February 28 in the International Journal of Pharmaceutics.
ver más...
Nanoparticles that mimic viruses can stimulate long lasting
immunity
Publicada el 02/28/2011.
Vaccine scientists say their "Holy Grail" is to stimulate immunity that lasts for a lifetime. Live viral vaccines such as
the smallpox or yellow fever vaccines provide immune protection that lasts several decades, but despite their
success, scientists have remained in the dark as to how they induce such long lasting immunity.
ver más...
Fingerprints of a gold cluster revealed
Publicada el 02/25/2011.
Nanometre-scale gold particles are currently intensively investigated for possible applications in catalysis, sensing,
photonics, biolabelling, drug carriers and molecular electronics. The particles are prepared in a solution from gold
salts and their reactive gold cores can be stabilised with various organic ligands.
ver más...
Virus-Mimicking nanoparticles can stimulate long-lasting immunity
Publicada en Nanomedicine Research - News, 02/24/2011.
Vaccine scientists say their "Holy Grail" is to stimulate immunity that lasts for a lifetime. Live viral vaccines such as
the smallpox or yellow fever vaccines provide immune protection that lasts several decades, but despite their
success, scientists have remained in the dark as to how they induce such long lasting immunity.
ver más...
Febrero 2011 Página 2

6. Nanomedicina
Clues to mystery of preterm delivery
Publicada el 02/24/2011.
Scientists know that calcifying nanoparticles are involved in many degenerative conditions including arthritis and
atherosclerosis.
ver más...
Tuning the collective properties of artificial nanoparticle
supercrystals
Publicada el 02/24/2011.
Due to precise positioning of the NCs within a 3-D superlattice, such systems are frequently referred to as
supercrystals (SCs) in analogy to crystals built of atoms.
ver más...
NanoBioConnect: A new tool to accelerate commercialization of
nanobiotechnology
Publicada el 02/24/2011.
The Center of Innovation for Nanobiotechnology (COIN) today announced the launch of an information-rich,
comprehensive nanobiotechnology information portal available to the public called NanoBioConnect.
ver más...
Prótesis articulares más seguras
Publicada el 02/24/2011.
Un grupo de investigadores del MIT está desarrollando recubrimientos para implantes médicos capaces de ser
cargados con múltiples medicamentos, incluyendo antibióticos que se liberan a través del tiempo.
ver más...
Engineered cells could usher in programmable cell therapies
Publicada el 02/24/2011.
In work that could jumpstart the promising field of cell therapy, in which cells are transplanted into the body to treat a
variety of diseases and tissue defects.
ver más...
Febrero 2011 Página 3

7. Nanomedicina
Modified RNA creates stable therapeutic nanoparticles
Publicada el 02/24/2011.
But by replacing a chemical group in the macromolecule, Dr. Guo says he and fellow researchers have found a way
to bypass RNase and create stable three-dimensional configurations of RNA, greatly expanding the possibilities for
RNA in nanotechnology.
ver más...
Enabling nanoparticles to penetrate deeply in tumors
Publicada el 02/24/2011.
Now, a large team of researchers from the Massachusetts Institute of Technology, have developed a solution to this
problem: multilayered, or multistage, nanoparticles that partially dissolve once they accumulate around tumors,
leaving behind a payload of nanoparticles a mere one-tenth the size of the original delivery vehicle.
ver más...
MIT engineers design new nanoparticle that could lead to vaccines
Publicada el 02/24/2011.
The new particles, consist of concentric fatty spheres that can carry synthetic versions of proteins normally produced
by viruses. These synthetic particles elicit a strong immune response comparable to that produced by live virus
vaccines but should be much safer.
ver más...
Simpler way of making proteins could lead to new nanomedicine
agents
Publicada el 02/23/2011.
Researchers have developed a simple method of making short protein chains with spiral structures that can also
dissolve in water, two desirable traits not often found together. Such structures could have applications as building
blocks for self-assembling nanostructures and as agents for drug and gene delivery.
ver más...
Febrero 2011 Página 4

8. Nanomedicina
New technology in human trials to spot cardiac disease
Publicada el 02/23/2011.
Cardiac disease is the focus of one of six ongoing major clinical trials of Rice's programmable bio-nano-chips
(PBNCs).
ver más...
Desarrollan un sistema de transporte de fármacos antitumorales
Publicada el 02/20/2011.
Científicos mexicanos trabajan en el desarrollo de un sistema de transporte de fármacos citotóxicos, que permitirá
inyectar de manera simultánea agentes de quimio y radioterapia, dirigidos específicamente a tumores y células
cancerosas, con lo que se reducirán los efectos tóxicos secundarios en tejidos y órganos sanos.
ver más...
Magnetic nanoparticles could track transplanted neural stem cells
following spinal injury
Publicada el 02/18/2011.
Tracking magnetic nanoparticles attached to stem cells transplanted into spinal cords to heal injuries could be an
effective way to monitor the healing process non-invasively say UK scientists.
ver más...
Tiny 'microworms' could be implanted under the skin for
continuous medical monitoring
Publicada el 02/17/2011.
Researchers at MIT and Northeastern have come up with a new system for monitoring biomedical indicators -- such
as levels of sodium or glucose in the blood -- that could someday lead to implantable devices that would allow, for
example, people with diabetes to check their blood sugar just by glancing at an area of skin.
ver más...
Fresh technology for new cell creation
Febrero 2011 Página 5

9. Nanomedicina
Publicada el 02/16/2011.
Enter the MODPLEUV project, which brought together Austrian, Czech and Polish researchers to successfully
develop a novel yet easy way to create nano-structured materials that would facilitate human cell development.
MODPLEUV is supported by EUREKA, the European platform for research and development (R&D).
ver más...
Unos nanotransportadores consiguen pasar
Publicada en Technology Review, 02/16/2011.
Un nuevo sistema de nanotransporte es capaz de colar tratamientos contra el cáncer a través de las defensas de las
células tumorales resistentes a los fármacos, ofreciendo esperanza a muchos pacientes de cáncer que se benefician
poco de los tratamientos farmacológicos existentes.
ver más...
Next-Generation sensor technology to be developed by Optiqua-
NTU Partnership
Publicada el 02/16/2011.
To enhance its contaminant-detection capability, Optiqua Technologies Pte Ltd is collaborating with Nanyang
Technological University (NTU) to tap on its expertise in biomolecular sciences and sensor technology.
ver más...
Tracking neural stem cells
Publicada el 02/14/2011.
Magnetic nanoparticles could be used to track neural stem cells after a transplant in order to monitor how the cells
heal spinal injuries, say UCL scientsts.
ver más...
Circulating tumor cell detection may be enhanced by nanoparticles
Publicada el 02/14/2011.
Tiny gold particles can help doctors detect tumor cells circulating in the blood of patients with head and neck cancer,
researchers at Emory and Georgia Tech have found.
ver más...
Febrero 2011 Página 6

10. Nanomedicina
Drug encapsulation and gene therapies use new data obtained on
liposomes
Publicada el 02/09/2011.
University of Granada scientists and the Spanish Higher Institute for Scientific Research (CSIC) have made
significant progress in understanding lipid membranes, which are extensively employed in the development of
cosmetic and drug products, and which have potential application in the field of nanotechnology.
ver más...
Precise new sensor employs hydrogels
Publicada el 02/09/2011.
Researchers are developing a new type of biological and chemical sensor that has few moving parts, is low-cost and
yet highly sensitive, sturdy and long-lasting.
ver más...
PATENTES
Patentes publicadas este mes
Publicada el 02/28/2011.
Fuente: Espacenet, USPTO
Febrero 2011 Página 7

11. Nanomedicina
Origen de los principales actores del mes
Publicada el 02/28/2011.
Fuente: Espacenet, USPTO
Principales titulares de las patentes del mes
Publicada el 02/28/2011.
Fuente: Espacenet, UPSTO
Febrero 2011 Página 8

12. Nanomedicina
Principales temas tratados en las patentes del mes
Publicada el 02/28/2011.
Fuente: Espacenet, UPSTO
Principales inventores que patentaron este mes
Publicada el 02/28/2011.
Fuente: Especenet, USPTO
Febrero 2011 Página 9

13. Nanomedicina
US20110033522A1: Reagents for inducing an immune response
Publicada el 02/24/2011.
Inventor: Reinherz Ellis L. Titular: Dana Farber Cancer Inst Inc (EE.UU.); Harvard College (EE.UU.); Massachusetts
Inst Technology (EE.UU.)
Resumen: The present disclosure relates to reagents and kits that are useful in a variety methods for inducing an
immune response.
ver más...
US20110038939A1: Therapeutic stable nanoparticles
Publicada el 02/24/2011.
Inventor: Lvov Yuri. Titulares: Univ Northeastern; Louisiana Tech University Res Foundation a Division of Louisiana
Tech University Foundation (EE.UU.)
Resumen: Stable colloid nanoparticles comprising poorly soluble drugs are disclosed.
ver más...
US20110033550A1: Nanoparticle carriers for drug administration
Publicada el 02/24/2011.
Inventor: Kalombo Lonji. Titular: CSIR (Sudáfrica)
Resumen: The invention provides a process for the production of nanoparticle carriers for drug delivery.
ver más...
US20110044893A1: Vascular targets for detecting, imaging and
treating ..
Publicada el 02/24/2011.
Inventor y Titular: Schnitzer Jan E (EE.UU.)
Resumen: Methods of delivering an agent in a tissue-specific manner, by targeting annexin A1, a derivative of
annexin A1, or a binding partner of annexin A1, are described.
ver más...
US20110027174A1: Nanotubes for cancer therapy and diagnostics
Febrero 2011 Página 10

14. Nanomedicina
Publicada el 02/24/2011.
Inventor y Titular: Buzatu Dan A (EE.UU.).
Resumen: The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubes
and other similar nanostructures.
ver más...
WO2011019211A2: Silk nanofiber nerve conduit and method for
producing thereof
Publicada el 02/24/2011.
Inventor: Park Young Hwan. Titular: Snu R&Db Foundation (Corea del Sur).
Resumen: The present invention relates to a silk nanofiber nerve conduit characterized in that fibroin nanofibers, are
stacked layer upon layer to form a porous conduit-shape; and a method for producing thereof.
ver más...
WO2011017456A2: Localized delivery of nanoparticles for
therapeutic and diagnostic applications
Publicada el 02/24/2011.
Inventor: Mirkin Chad A. Titular: Univ Northwestern (EE.UU.)
Resumen: The present invention is directed to compositions and methods of localized delivery of a functionalized
nanoparticle.
ver más...
US20110045031A1: Use of buckysome or carbon nanotube for drug
delivery
Publicada el 02/24/2011.
Inventor: Hirsch Andreas. Titular: Ensysce Biosciences Inc (EE.UU.)
Resumen: Compositions and methods for administering a therapeutic agent to a mammal are disclosed.
ver más...
Febrero 2011 Página 11

15. Nanomedicina
US20110045055A1: Medical devices containing therapeutic agents
Publicada el 02/24/2011.
Inventor: Hingston John. Titular: Boston Scient Scimed Inc (EE.UU.)
Resumen: According to one aspect of the invention, implantable or insertable medical devices are provided which
can delay release of one or more therapeutic agents for a predetermined time after implantation in a subject.
ver más...
DK0912734T3: Chimeric heteromultimer adhesins
Publicada el 02/24/2011.
Inventor: Sliwkowski Mark. Titular: Genentech Inc (EE.UU.)
Resumen: Chimeric heteromultimer adhesins that bind the ligand of natural heteromultimeric receptors and uses
therefor are disclosed.
ver más...
WO2011017313A1: Method of administering non-viral nucleic acid
vectors to the eye
Publicada el 02/24/2011.
Inventor: Cooper Mark J. Titular: Copernicus Therapeutics Inc (EE.UU.)
Resumen: Intravitreal administration of nucleic acid vectors leads to transfection and expression of the nucleic acid
vectors in retinal pigment epithelium.
ver más...
WO2011017442A2: Anti-RSV immunogens and methods of
immunization
Publicada el 02/24/2011.
Inventor: Anderson Larry J. Titular: US Government (EE.UU.)
Resumen: Immunogenic polypeptides corresponding to one or more RSV G glycoproteins, or analogues thereof, are
provided as components of vaccines.
ver más...
Febrero 2011 Página 12

16. Nanomedicina
WO2011017690A2: Intracellular delivery of contrast agents with
functionalized nanoparticles
Publicada el 02/24/2011.
Inventor: Mirkin Chad A. Titular: Univ Northwestern (EE.UU.)
Resumen: The present invention is directed to compositions and methods for intracellular delivery of a contrast agent
with a functionalized nanoparticle.
ver más...
US20110038905A1: Skin anti-aging agent for external use
Publicada el 02/24/2011.
Inventores: Aimi Makiko. Titular: Fujifilm Corp (Japón)
Resumen: The present invention provides a skin anti-aging agent for external use, which comprises protein
nanoparticles containing an active ingredient.
ver más...
US20110034916A1: Nanoparticle-mediated microwave treatment
methods
Publicada el 02/24/2011.
Inventor y Titular: Te Alexis. Titulares(EE.UU.)
Resumen: A method is provided for using magnetic nanoparticles to enhance microwave therapies for treating cells
and tissues.
ver más...
WO2011012867A1: A delivery system comprising a silicon-
containing material
Publicada el 02/24/2011.
Inventor: Saffie-Siebert Roghieh. Titular: Sisaf Ltd (Reino Unido)
Resumen: A composition comprising nanoparticles of a hydrolysable silicon-contain material for use as a delivery
system for a bioactive ingredient and a method of promoting the controlled release of orthosilicic acid.
ver más...
Febrero 2011 Página 13

17. Nanomedicina
US20110033419A1: Methods and compositions for treating cancer
Publicada el 02/24/2011.
Inventor: Aurellan Laure. Titular: Univ Maryland (EE.UU.)
Resumen: The invention further relates to pharmaceutical compositions comprising HSV-2 virus, wherein the virus
lacks protein kinase activity of ICP10.
ver más...
WO2011012721A1: Carrier linked pramipexole prodrugs
Publicada el 02/23/2011.
Inventor: Rau Harald. Titular: Ascendis Pharma AS (Dinamarca)
Resumen: The present invention relates to a carrier linked pramipexole prodrug or a pharmaceutical acceptable salt
thereof, wherein pramipexole is bound via a linker to a polymeric carrier.
ver más...
WO2011014562A1: Methods and devices for targeted injection of
microspheres
Publicada el 02/23/2011.
Inventor: Kleinstreuer Clement. Titular: Univ North Carolina State (EE.UU.)
Resumen: A "Smart Micro-catheter" (SMC) system comprising a device for controlled particle release and drug
delivery into a blood vessel, hepatic artery or any patho-physiological target is disclosed.
ver más...
WO2011019954A2: Intracochlear drug delivery to the central
nervous system
Publicada el 02/23/2011.
Inventor: Ivri Yehuda. Titular: Ivri Yehuda (EE.UU.)
Resumen: The present invention is directed to method and system for delivery of brain-targeted drugs to the
cerebrospinal fluid via the perilymphatic fluid of the inner ear.
ver más...
Febrero 2011 Página 14

18. Nanomedicina
US20110038900A1: Nanoparticles for use in pharmaceutical
compositions
Publicada el 02/22/2011.
Inventor: Chakrapani Aravind. Titular: Novartis AG (Suiza)
Resumen: In various aspects of the present invention, nanoparticle compositions are provided which comprise (a)
nanoparticles comprising at least one biodegradable polymer and (b) at least one pharmaceutical associated with the
nanoparticles.
ver más...
EVENTOS, CURSOS Y SEMINARIOS
Concertation des nanorevetements (stakeholder dialogue on
nanocoatings)
Publicada en NanoForum.org-Events, 02/28/2011.
Pour enrichir lexpertise par la concertation, progresser dans lécoute et la compréhension des autres points de vues
(parties apprenantes) et approfondir les controverses.
Fecha: 15 March 2011 Lugar: Paris, France
ver más...
INRS Occupational Health Research Conference 2011
Publicada el 02/23/2011.
Occupational Health Research Conference 2011: Risks associated to Nanoparticles and Nanomaterials.
Fecha: 05 - 07 April 2011 Lugar: Nancy, France
ver más...
IV Conferencia Anual de las Plataformas Tecnológicas de
Investigación Biomédica
Publicada el 02/23/2011.
La cita anual de las tres Plataformas Tecnológicas de Investigación Biomédica bordará la cooperación farma-biotech,
como una necesidad puesta de manifiesto en el modelo de investigación de nuevos medicamentos y tecnologías
sanitarias.
Fecha: 28 de febrero - 1 de marzo de 2011 Lugar: Palacio Municipal de Congresos de Madrid.
ver más...
Febrero 2011 Página 15

19. Nanomedicina
Nanotubes and Nanocomposites 2011
Publicada el 02/23/2011.
Will focus on research and development in all nano-particles, polymer processing and application, as well as market
direction, growth and potential for commercialisation.
Fecha: April 06 - 07, 2011 Lugar: Le Meridien Brussels, Brussels, Belgium
ver más...
ImagineNano
Publicada el 02/23/2011.
Extensive thematic conferences will be held in parallel and a huge industrial exhibition carried out with the latest
nanotrends for the future. Fecha: Apr 11 - 14, 2011 Lugar: Bilbao, España
ver más...
COIN Hosts Nanomedicine Commercialization Workshop
Publicada el 02/23/2011.
The topic of the workshop will be Actionable Strategies for Company Building & Moving to Market.
Fecha: Mar 29, 2011 Lugar: Charlotte North Carolina, EE.UU.
ver más...
NanoManufacturing Conference & Exhibits
Publicada el 02/23/2011.
This conference will highlight the current, near-term, and future applications of nanotechnology and how they are
transforming the way we manufacture products.
Fecha: Apr 05 - 06, 2011 Lugar: Oakbrook Terrace (Chicago) IL, EE.UU.
ver más...
2nd NanoDiaRA Seminar
Publicada el 02/23/2011.
NanoDiaRA, a consortium of 15 partners, is looking forward to welcoming interested people from research and
development, industry and society and to show you new approaches of in-vitro and in-vivo technologies.
Fecha: 18 March 2011 Lugar: Neuchâtel, Switzerland
ver más...
Febrero 2011 Página 16

20. Nanomedicina
Conference Innovation in Healthcare: from Research to Market
Publicada el 02/23/2011.
The objective of the 2011 conference is to produce an analysis of the strengths, weaknesses, opportunities and
threats (SWOT) for innovation in healthcare and make specific recommendations that will be addressed to policy-
makers and stakeholders.
Fecha: 30-31 March 2011 Lugar: Brussels
ver más...
5th Concertation and Consultation Workshop on Micro-Nano-Bio
convergence Systems
Publicada el 02/23/2011.
Co-organized by the European Commission and IKERLAN-IK4 a private not-profit Technological Research Centre in
the north of Spain. Fecha: April 05 - 06, 2011 Lugar: Mondragón, Spain.
ver más...
Latin American Biomedical Nanotechnology Showcase
Publicada el 02/23/2011.
Workshop participants must be registered users of ICPC-Nanonet. Registration is free.
Fecha: 23 March 2011
Lugar: in internet, Great Britain
ver más...
Seminar on Micro- and Nanotechnology Based Tools for Early
Detection of Diseases
Publicada en European Technology Platform of Nanomedicine - Events, 02/18/2011.
NanoDiaRA, a consortium of 15 partners, is looking forward to welcoming interested people from research and
development, industry and society and to show you new approaches of in-vitro and in-vivo technologies.
Fecha: 07 March 2011 Lugar: Neuchâtel, Switzerland
ver más...
Febrero 2011 Página 17

21. Nanomedicina
MicroMaterials Nanomechanical Testing Technical Seminar
Publicada en AzoNanotechnology-Eventos, 02/18/2011.
Each Micro Materials Nanomechanical Testing Technical Seminar will provide an introduction to the theory, current
research and live demonstrations.
Fecha: March 01, 2011 Lugar: Oxford University Begbroke Science Park, EE.UU.
ver más...
Nanotechnologies et risques: responsabilités et assurances?
Publicada en NanoForum.org-Events, 02/18/2011.
Organized by: Vivagora
Fecha: 22 March 2011
Lugar: Paris, France
ver más...
ARTÍCULOS-CIENTÍFICOS
Principales investigadores que publicaron este mes
Publicada el 02/28/2011.
Fuente: Scopus
Febrero 2011 Página 18

22. Nanomedicina
Principales entidades con publicaciones este mes
Publicada el 02/28/2011.
Fuente: Scopus
Principales temas tratados en los artículos científicos del mes
Publicada el 02/28/2011.
Fuente: Scopus
Febrero 2011 Página 19

23. Nanomedicina
"Off-On" Electrochemical Hairpin-DNA-Based Genosensor
Publicada el 02/23/2011.
Autor: Farjami E.
Resumen: A simple and robust "off-on" signaling genosensor platform with improved selectivity for single-nucleotide
polymorphism (SNP) detection based on the electronic DNA hairpin molecular beacons has been developed.
ver más...
Biostability of y-Fe2O3 nano particles
Publicada el 02/23/2011.
Autor: Kwon-Jai Leea. Resumen: This study examined the cytotoxic effects of the y-Fe2O3 magnetic nanoparticles
(GMNs) on a range of tumor cell lines.
ver más...
Size and surface charge of gold nanoparticles..
Publicada el 02/23/2011.
Autor: Schleh C. Resumen: In this study, radiolabelled gold nanoparticles in different sizes (1.4200 nm) with negative
surface charge and 2.8 nm nanoparticles with opposite surface charges were administered by intra-oesophageal
instillation into healthy adult female rats.
ver más...
Problems and challenges in the development and validation of
human cell-based assays..
Publicada el 02/23/2011.
Autor: Oostingh GJ. Resumen: In a collaborative work between European laboratories, existing immunological and
toxicological in vitro assays were tested and compared for their suitability to test effects of nanoparticles on immune
responses.
ver más...
Solid lipid nanoparticles reduce systemic toxicity of docetaxel
Febrero 2011 Página 20

24. Nanomedicina
Publicada el 02/23/2011.
Autor: Gao Y. Resumen: In this study, the new docetaxel-loaded solid lipid nanoparticles (DSNs) were prepared, and
systemic toxicity of DSNs in different animals was comprehensively investigated for allergenicity and vascular
irritation in mice and beagle dogs.
ver más...
Cellular response of RAW 264.7 to spray-coated multi-walled carbon
nanotube films
Publicada el 02/23/2011.
Autor: Chen H. Resumen: In this paper, the authors studied the potential health effect of carbon nanotube (CNT) films
fabricated with three commercial surfactants (sodium cholate, sodium dodecyl sulfate, and triton X-100).
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Analysis of Amyloid-b; Peptides in cerebrospinal fluid samples by
capillary electrophoresis
Publicada el 02/23/2011.
Autor: Verpillot R. Resumen: We report a CE-LIF method for the separation and detection of five synthetic amyloid-
beta; peptides corresponding to an important family of CSF-biomarkers in the context of Alzheimer disease (AD).
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Human skin penetration of gold nanoparticles through intact and
damaged skin
Publicada el 02/23/2011.
Autor: Larese Filon F. Resumen: In this study, experiments were performed with gold nanoparticles (AuNPs) using
the Franz diffusion cell method with intact and damaged human skin.
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Hazard identification of particulate matter on vasomotor
dysfunction and atherosclerosis
Febrero 2011 Página 21

25. Nanomedicina
Publicada el 02/23/2011.
Autor: Pøller. Resumen: The development and use of nanoparticles have alerted toxicologists and regulators to
issues of safety testing.
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Contribution of nano-copper particles to in vivo liver dysfunction
and cellular damage
Publicada el 02/23/2011.
Autor: Manna P. Resumen: In this study, the oxidative stress responsive cell signaling in nano-copper-induced
hepatic dysfunction and cell death was investigated.
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Differential pro-inflammatory effects of metal oxide nanoparticles
and their soluble ions
Publicada el 02/23/2011.
Autor: Cho WS. Resumen: In this study, nickel, zinc, and copper oxide nanoparticles (NiONP, ZnONP, and CuONP)
and their aqueous extracts (AEs) were applied to A549 lung epithelial cells to determine the cytotoxicity, IL-8
production, and activation of transcription factors.
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An effective strategy for the synthesis of biocompatible gold
nanoparticles
Publicada el 02/23/2011.
Autor: Chanda N. Resumen: In this study, cinnamon-coated gold nanoparticles (Cin-AuNPs) were synthesized by a
"green" procedure, and the detailed characterization was performed by physico-chemical analysis.
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Spherical bioactive glass particles and their interaction with human
mesenchymal stem cells
Publicada el 02/23/2011.
Autor: Labbaf S. Resumen: In this study, sub-micron particles of bioactive glass (SMBGs) were synthesised and
characterised and the effect of exposure of SMBGs to human mesenchymal stem cells (hMSCs) on cell viability,
metabolic activity and proliferation were determined using the LIVE/DEAD, MTT, total DNA and LDH assays.
Febrero 2011 Página 22

26. Nanomedicina
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Human skin penetration of gold nanoparticles through intact and
damaged skin
Publicada en Virtual Journal of Nanotechnology Environment, Health and Safety, 02/16/2011.
Autor: Larese Filon F. Resumen: In this study, experiments were performed with gold nanoparticles (AuNPs) using
the Franz diffusion cell method with intact and damaged human skin.
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REPORTES, LIBROS, OTRAS
Nanotoxicology: An Interdisciplinary Challenge
Publicada el 02/23/2011.
This Review seeks to cast light on the phenomena that may occur as nanoobjects interact with cells, tissues, and
organisms and points out the aspect of reliability of studies with specific examples from the literature including a
discussion of inadequate methods together with recommendations how to avoid this in the future.
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Nanotechnology in Medicine - Pharma-Reports
Publicada el 02/23/2011.
Nanotechnology is already being used in products in its passive form, such as cosmetics and sunscreens, and it is
expected that in the coming decades, new phases of products, such as better batteries and improved electronics
equipment, will be developed and have far©reaching implications.
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La nanotecnología española se coloca a la vanguardia internacional
del sector
Publicada el 02/23/2011.
El objetivo del Plan Nacional de I+D+i del Gobierno 2008-2011, es mejorar la competitividad de la industria española
mediante la generación de cambios sustanciales en un amplio rango de sectores a través de la implementación y el
desarrollo de nuevas aplicaciones y convergencias de diferentes tecnologías y disciplinas, entre las que destacan la
nanociencia y nanotecnología (N&N).
Febrero 2011 Página 23

27. Nanomedicina
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Drug Regulation in the Modern Era
Publicada el 02/23/2011.
Remarks of Margaret A. Hamburg, M.D. Commissioner of Food and Drugs
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Nanotechnology in Drug Delivery - Technological Improvements
and Novel Approaches
Publicada el 02/23/2011.
The report provides a comprehensive insight into the role of Nanotechnology in Drug Delivery. The report also
provides a detailed analysis of market characterization of nanotechnology in drug delivery market in terms of its
market size, segmentation by key geography types and the major market drivers and barriers.
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Biochips - Products, Applications, Technologies and End-use
Markets Growth Analysis
Publicada el 02/23/2011.
Global Market Watch: Global biochips market is forecasted to reach US$9.1 billion by 2015 with a CAGR of 20.9%
during 2009-2015; the massive CAGR is primarily supported by Asia-Pacific followed by the European Union.
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Nanomedicines in Argentina 2011
Publicada el 02/15/2011.
Alejandro Sosnik and Eder Romero present their personal view of the current Nanomedicine landscape in Argentina.
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Febrero 2011 Página 24