Placenta previa occurs when the placenta is located low in the uterus, covering or near the cervical opening. There are four degrees of placenta previa based on how much of the cervical os is covered. Risk factors include cesarean delivery, uterine surgery, multiple gestations, advanced maternal age, and multiple pregnancies. Symptoms include painless third trimester bleeding. Placental abruption occurs when the placenta separates from the uterine wall before delivery and can cause bleeding, back pain, and contractions. Risk factors include hypertension, cocaine use, smoking, and prior abruption. Management depends on gestational age and degree of maternal and fetal compromise.
Antepartum haemorrhage (APH) is defined as bleeding from or in to the genital tract, occurring from 24+0 weeks of pregnancy and prior to the birth of the baby. The most important causes of APH are placenta praevia and placental abruption, although these are not the most common.
Types 1 and 2 are classified as minor placental praevia as these typically result in minor antepartum haemorrhaging. Types 3 and 4 are referred to as major placental praevia due to the risk of heavy haemorrhaging in the case of a rupture due to the location of placental attachment.
Antepartum haemorrhage (APH) is defined as bleeding from or in to the genital tract, occurring from 24+0 weeks of pregnancy and prior to the birth of the baby. The most important causes of APH are placenta praevia and placental abruption, although these are not the most common.
Types 1 and 2 are classified as minor placental praevia as these typically result in minor antepartum haemorrhaging. Types 3 and 4 are referred to as major placental praevia due to the risk of heavy haemorrhaging in the case of a rupture due to the location of placental attachment.
A miscarriage, or spontaneous abortion, is an event that results in the loss of a fetus before 20 weeks of pregnancy. It typically happens during the first trimester, or first three months, of the pregnancy. Miscarriages can happen for a variety of medical reasons, many of which aren't within a person's control.
A miscarriage, or spontaneous abortion, is an event that results in the loss of a fetus before 20 weeks of pregnancy. It typically happens during the first trimester, or first three months, of the pregnancy. Miscarriages can happen for a variety of medical reasons, many of which aren't within a person's control.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
1. PLACENTA PREVIA
DEFINITION
IN PLACENTA PREIVA , THE PLACENTA IS LOCATED OVER
OR VERY NEAR THE INTERNAL OS. FOUR DEGREES OF THE
ABNORMALITY HAVE BEEN RECOGNIZED:
1. TOTAL PALCENTA PREIVA. THE INTERNAL CERVICAL OS
IS COVERED COMPLETELY BY PLACENTA
2. PARTIAL PLACENTA PREVIA. THE INTERNAL OS IS
PARTIALLY COVERED BY PLACENTA
3. MARGINAL PLACENTA PREVIA . THE EDGE OF THE
PLACENTA IS AT THE MARGIN OF THE INTERNAL OS.
4. LOW -LYING PLACENTA. THE PLACENTA IS IMPLANTED
IN THE LOWER UTERINE SEGMENT SUCH THAT THE
PLACENTAL EDGE ACTUALLY DOES NOT REACH THE
INTERNAL OS BUT IS IN CLOSE PROXIMITY TO IT .
2. PLACENTAL PRESENTATION
• When the placenta lies directly over the
internal os
• The estimated incidence of placenta
praevia at term is 0.5%
• Determining placental location by
ultrasound examination–18-22 weeks of
gestation
3. RISK FACTORS OF PLACENTAL PRESENTATION
• Cesarean birth
• Surgery on the uterus
• Twins or triplets
• Over the age of 35
• More than four pregnancies
4. SYMPTOMS OF PLACENTAL PRESENTATION
• Painless bleeding during the third trimester
• Premature contractions
• Baby is breech, or in transverse position
• Uterus measures larger than it should according to gestational age
5. PLACENTAL ABRUPTION
THE SEPARATION OF THE PLACENTA FROM ITS
SITE OF IMPLANTATION BEFORE THE DELIVERY
OF THE FETUS HAS BEEN VARIOUSLY CALLED
PLACENTAL ABRUPTION , ABRUPTION
PLACENTAE, ACCIDENTAL HEMORRHAGE AND
PREMATURE SEPARATION OF THE NORMALLY
IMPLANTED PLACENTA .
6. ETIOLOGY.
IT IS MORE COMMON:
-AFRICAN -AMERICAN WOMEN THAN WHITE OR LATIN-
AMERICAN WOMEN .
-PREGNANCY-INDUCED OR CHRONIC HYPERTENSION.
-PRETERM PREMATURELY RUPTURED MEMBRANES HAVE
HAVE BEEN ASSOCIATED WITH AN INCREASED
INCIDENCE OF PREMATURE PLACENTAL SEPARATION.
-EXTERNAL TRAUMA COULD BE IMPLICATED ONLY IN 3
OF 207 CASES OF SEVERE PLACENTAL ABRUPTION . -
COCAINE ABUSE
-UTERINE LEIOMYOMA, ESPECIALLY IF LOCATED BEHIND
THE PLACENTAL IMPLANTATION
7. CLINICAL DIAGNOSIS
IT IS EMPHASIZED THAT THE SIGNS AND SYMPTOMS WITH
ABRUPTION PLACENTAE CAN VARY CONSIDERABLY.
IN 22 % OF CASES IDIOPATHIC PRETERM LABOR WAS
CONSIDERED TO BE THE DIAGNOSIS UNTIL SUBSEQUENT
FETAL DISTRESS - INCLUDING FETAL DEATH , SERIOUS
BLEEDING, BACK PAIN, UTERINE TENDERNESS , RAPID
UTERINE CONTRACTIONS OR PERSISTENT UTERINE
HYPERTONUS- WERE DETECTED SINGLY OR MORE OFTEN
IN COMBINATION. IMPORTANTLY , NEGATIVE FINDINGS
WITH ULTRASOUND EXAMINATION DO NOT EXCLUDE
LIFE-THREATENING PLACENTAL ABRUPTION
8. • Uteroplacental Apoplexy (Couvelaire Uterus). In the more sever forms of
placental abruption , widespread extravasation of blood into the uterine
musculature and beneath the uterine serosa is found. This phenomenon of
uteroplacental apoplexy that is frequently called Couvelaire uterus . Such
effusions of blood are also occasionally seen beneath the tubal serosa , in the
substance of the ovaries , as well as free in the peritoneal cavity .
9. PLACENTA ACCRETA
• When the placenta (or part of the placenta) invades and is inseparable from the
uterine wall
• Placenta accreta can cause bleeding during the third trimester and severe blood loss
during delivery
• Most cases can be found during pregnancy with a routine ultrasound exam
• Sometimes, it is not discovered until the baby is born
• Hysterectomy often needs to be done right after delivery to prevent life-threatening
blood loss
11. TEAR OFF OF A NORMALLY ATTACHED PLACENTA
• Placental abruption is defined as premature separation of a normally implanted
placenta
• The risk to the fetus depends on both the severity of the abruption and the gestational
age at which the abruption occurs
• The danger to the mother is posed primarily by the severity of the abruption
12. RISK FACTORS
• Placental abruption in a previous pregnancy, unless the abruption was caused by abdominal trauma, assuming the trauma isn't
repeated in the current pregnancy
• Chronic high blood pressure (hypertension)
• High blood pressure during pregnancy, resulting in preeclampsia or eclampsia
• A fall or other type of blow to the abdomen
• Smoking
• Cocaine use during pregnancy
• Early rupture of membranes, which causes leaking amniotic fluid before the end of pregnancy
• Infection inside of the uterus during pregnancy (chorioamnionitis)
• Carrying more than one baby
• Being older, especially after age 40
13. SYMPTOMS OF PLACENTAL ABRUPTION
• Vaginal bleeding and abdominal pain
• The amount of vaginal bleeding correlates poorly with the degree of abruption
• Stillbirth occurring in most cases in which there is greater than 50% placental
separation
• The uterus is frequently tender and may feel hard on palpation
• Backache may be the only symptom, especially when the placental location is
posterior
14. MANAGEMENT
The management of placental abruption depends on:
• the presentation
• the gestational age
• the degree of maternal and fetal compromise