The document categorizes diseases into three categories based on their priority, identifies specific pathogens that fall into categories A, B and C, and provides brief descriptions of standard precautions and treatment recommendations for each pathogen. Category A diseases pose the highest risk to national security and public health. Category B diseases have lower risks while Category C diseases have emerging pathogens that could potentially be engineered for mass dispersion. Standard precautions and supportive care along with antibiotics are recommended treatments for many pathogens, while antivirals may help for some viral diseases.

2.  Category A: Highest priority diseases that pose a risk to
national security, are easily transmitted, have high morbidity
and mortality, would have a major public health impact and
cause panic, and require special public health preparedness.
 Category B: Moderate priority diseases with lower morbidity
and mortality and more difficult to disseminate.
 Category C: High priority diseases that have the potential to
cause significant morbidity and mortality and are emerging
pathogens that could be engineered for mass dispersion.

3.  Anthrax (Bacillus anthracis)
 Botulism (Clostridium botulinum toxin)
 Plague (Yersinia pestis)
 Smallpox (Variola major)
 Tularemia (Francisella tularensis)
 Viral haemorrhagic fevers (e.g. Ebola)

4.  Brucellosis (Brucella species)
 Epsilon toxin of Clostridium perfringens
 Food Bacterium (Salmonella species, Escherichia coli O157:H7,
Shigella)
 Glanders (Burkholderia mallei)
 Melioidosis (Burkholderia pseudomallei)
 Psittacosis (Chlamydia psittaci)
 Q fever (Coxiella burnetii)
 Ricin: Ricinus communis (castor beans)
 Staphylococcal enterotoxin B
 Typhus fever (Rickettsia prowazekii)
 Viral encephalitis (Venezuelan equine encephalitis, eastern
equine encephalitis, western equine encephalitis)
 Water safety threats (Vibrio cholerae, Cryptosporidium parvum)

5.  H1N1 Influenza
 Hantavirus
 HIV/AIDS
 NipahVirus
 SARS

7.  Standard precautions
 Treatment: large early doses of intravenous
and oral antibiotics for 60 days may be life-
saving, such as ciprofloxacin, doxycycline,
erythromycin, penicillin, or vancomycin. FDA-
approved agents include ciprofloxacin,
doxycycline, and penicillin.

8.  Standard precautions
 Supportive care and antitoxin for severe
symptoms

9.  Standard precautions
 Supportive care and antibiotics

10.  Standard precautions
 Supportive care, fluids, antibiotics for
secondary infection, vaccination with 2 to 5
days

11.  Standard precautions
 Treatment:Tularemia is difficult to diagnose and
can easily be mistaken for other, more common,
illnesses. Blood tests and cultures can help
confirm the diagnosis. Antibiotics used to treat
tularemia include streptomycin, gentamicin,
doxycycline, or ciprofloxacin.Treatment usually
lasts 10 to 21 days. Streptomycin is the drug of
choice. Gentamicin is considered an acceptable
alternative.

12.  Standard precautions
 No cure exists, treatment is supportive

14.  Standard precautions
 Treatment:Tetracycline, rifampin,
streptomycin, and gentamicin are effective if
given for several weeks as bacteria incubate
within cells. Multiple antibiotics may be
necessary.The gold standard treatment is
streptomycin 1 g for 14 days and oral
doxycycline 100 mg twice daily for 45 days.
Another regimen is doxycycline plus rifampin
twice daily for 6 weeks.

15.  Standard precautions
 Treatment:There has been very little
progress toward the assembly of a good
human immunogen against C. perfringens or
any type of anti-toxin, and within the event of
a terrorist attack, no prophylactic measures
would possibly be accessible to be used by
the general public.

16.  Standard precautions
 Supportive with antibiotics for severe cases

17.  Standard precautions
 Oral amoxicillin/clavulanate, doxycycline, or
trimethoprim/sulfamethoxazole may be used
for 30 to 150 days depending on the degree of
the infection.

18.  Standard precautions
 Treatment: Initially intravenous ceftazidime
should be administered 10 to 14 days.
Meropenem, imipenem, and cefoperazone-
sulbactam combination are also active.
Intravenous amoxicillin-clavulanate may be used
if none of the above four drugs is available.
Eradication or maintenance treatment with co-
trimoxazole and doxycycline is recommended
for 12 to 20 weeks to reduce the rate of
recurrence.

19.  Standard precautions
 Treatment:The infection is treated with
tetracycline or chloramphenicol. For initial
treatment of ill patients, doxycycline hyclate
may be administered intravenously.
Remission is usually evident within 48 to 72
hours, but treatment must continue for at
least 10 to 14 days after fever subsides.

20.  Standard precautions
 Treatment:Antibiotics include doxycycline,
tetracycline, chloramphenicol, ciprofloxacin,
ofloxacin, and hydroxychloroquine. Chronic Q
fever may require up to four years of
treatment with doxycycline and quinolones
or doxycycline with hydroxychloroquine.

21.  Standard precautions
 Treatment: Charcoal lavage and supportive
care.

22.  Standard precautions
 Treatment:Antibiotics such as oxacillin,
cefazolin, clindamycin, vancomycin, or
linezolid with supportive care.

23.  Standard precautions

24.  Standard precautions
 Treatment: Supportive

25.  Standard precautions
 Treatment: Depends on the pathogen. Most
are supportive, but antibiotics may shorten
the course.

27.  Standard precautions
 Treatment: Supportive

28.  Standard precautions
 Treatment: Depends on the stage of the
disease and any concomitant opportunistic
infections. In general, the goal of treatment is
to prevent the immune system from
deteriorating using antiretroviral therapy
(HAART). In addition, prophylaxis for specific
opportunistic infections is indicated.

29.  Standard precautions
 Treatment: Depends on the stage of the
disease and any concomitant opportunistic
infections. In general, the goal of treatment is
to prevent the immune system from
deteriorating using antiretroviral therapy
(HAART). In addition, prophylaxis for specific
opportunistic infections is indicated.

30.  Standard precautions
 Treatment: Supportive measures as there is
no definitive treatment. Ribavirin may help.

31.  Standard precautions
 Treatment: Supportive care with oxygen and
ventilation.Antiviral medications and
steroids may reduce lung swelling.