This document discusses using big data analytics for operational and clinical decision support in healthcare. It outlines how analytics can help optimize decisions for patients, administrators, providers and policy makers by analyzing structured and unstructured data from various sources. The document proposes creating an operational decision support center and clinical decision support center to help coordinate patient care, anticipate needs, detect bottlenecks and support clinical decisions with data-driven insights. The goal is to move from rule-based systems to more precise, predictive and transparent decision making approaches.