Genesis is divided into two main sections - chapters 1-11 covering creation to the Tower of Babel, and 12-50 covering the patriarchs Abraham, Isaac, and Jacob. It begins with God creating the heavens and the earth in six days and ends with Joseph's body being taken back to Canaan. Key people and events included Adam and Eve, the fall of man, Noah and the flood, the Tower of Babel, God's covenant with Abraham, the stories of Isaac being offered as a sacrifice and Jacob wrestling with God.