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ASSESSING DEMOGRAPHIC DISPARITIES IN UTILIZATION OF INHALED CORTICOSTEROIDS AMONG PATIENTS WITH PERSISTENT ASTHMA Varun Vaidya1, PhD, Gautam Partha2, B.Pharm, Sara Holl2, BSPS1Assistant Professor , 2Research Assistant,The Pharmaceutical Care and Outcomes Research Lab, College of Pharmacy, The University of Toledo, Toledo, Ohio, USA INTRODUCTION RESULTS: RESULTS contd.. DISCUSSION AND STUDY IMPLICATIONS Table 2:  ICS use and demographic characteristics ,[object Object]

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ASSESSING DEMOGRAPHIC DISPARITIES IN UTILIZATION OF INHALED CORTICOSTEROIDS AMONG PATIENTS WITH PERSISTENT ASTHMA

  • 1.
  • 2. African Americans were found to have much lower odds of using ICSs when compared to Whites (OR=0.495, CI=0.248-0.987).
  • 3. Insured patients had significantly higher odds for use of ICSs (OR=2.378, CI=1.106-5.110) compared to uninsured patients.
  • 4. The findings held true even after adjusting for other demographic factors.
  • 5. The lack of use of ICS is a cause of concern especially amongst minorities and uninsured population. This underuse not only makes the control of disease difficult, but also increases associated healthcare expenditures.
  • 6. Studies have shown that hospitalizations and emergency department visits for infrequent inhaled corticosteroid users were significantly more when compared with consistent users.9
  • 7. African Americans were found to have much lower odds of using ICS when compared to Caucasians. Roots of this disparity may lie in lack of access to care and inconsistencies in health care treatment using U.S. National Heart, Lung, and Blood Institute (NHLBI) guidelines.10
  • 8. Insurance status was also found to be a significant predictor of inhaled corticosteroids use. Insurance status has been linked to the utilization of necessary healthcare services.10 With the new advent of the healthcare reform bill, we hope that the number of uninsured patients with asthma will be reduced. Increased access to health insurance will likely improve access to ICS and eliminate disparities.
  • 9. Poor adherence to ICS is a growing issue in managing asthma amongst the population with persistent asthma and investigating disparities in utilization provides important information about subpopulations that are vulnerable to underutilization of ICS. Results from this study help to identify such populations in an effort to direct policy makers to formulate specific policies aimed at diminishing the existing disparities.
  • 10. The results also help to educate and inform healthcare providers about the issue of underutilization of ICS and the current existing disparities.
  • 11. Limitations: The survey used patients suffering from asthma in only four states. Therefore, these findings cannot be generalized to the national asthma population. Survey related recall bias and inability to establish causal effect are limitations of this study.
  • 12. Asthma affects an estimated 300 million people of all ages and ethnic backgrounds worldwide and causes significant morbidity and mortality in spite of existence of well established guidelines for proper management.1
  • 13. The economic burden for asthma has been amplified by the poor control seen in patients. Utilization costs attributed to asthma rank amongst the highest for chronic diseases.2 This poor control has been attributed to inappropriate utilization of asthma medications.
  • 14.
  • 15. The researchers used the four-state study which was conducted as a part of NAS in Alabama, California, Illinois, and Texas.
  • 16.
  • 17.
  • 18. Independent variables used in the analysis included demographic characteristics such as age, race, gender, ethnicity and income level.
  • 20. Chi square test was used to determine if there are any demographic differences concerning the reported use of inhaled corticosteroids.
  • 21.
  • 22. Further research needs to be done probing the cause of these disparities and why, despite treatment guidelines and recommendations, the underuse of ICS continue to exist. Table 1: ICS use and demographic characteristics REFERENCES: Masoli M, Fabian D, Holt S, Beasley R. The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004;59:469-78. Bahadori K, Doyle-Waters MM, Marra C, et al. Economic burden of asthma: a systematic review. BMC Pulm Med 2009;9:24. Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy ClinImmunol 2007;120:S94-138. Carlton BG, Lucas DO, Ellis EF, Conboy-Ellis K, Shoheiber O, Stempel DA. The status of asthma control and asthma prescribing practices in the United States: results of a large prospective asthma control survey of primary care practices. J Asthma 2005;42:529-35. Plaza V, Serra-Batlles J, Ferrer M, Morejon E. Quality of life and economic features in elderly asthmatics. Respiration. 2000;67(1):65-70. Accordini S, Bugiani M, Arossa W, et al. Poor control increases the economic cost of asthma. A multicentre population-based study. Int Arch Allergy Immunol. 2006;141(2):189-198. Smith DH, Malone DC, Lawson KA, Okamoto LJ, Battista C, Saunders WB. A national estimate of the economic costs of asthma. Am J RespirCrit Care Med. Sep 1997;156(3 Pt 1):787-793. Stingone JA, Claudio L. Components of recommended asthma care and the use of long-term control medication among urban children with asthma. Med Care 2009;47:940-7. Colice G, Wu EQ, Birnbaum H, Daher M, Maryna BM. Use of inhaled corticosteroids and healthcare costs in mild persistent asthma. J Asthma 2007;44:479-83. Anis AH, Lynd LD, Wang XH, et al. Double trouble: impact of inappropriate use of asthma medication on the use of health care resources. CMAJ. Mar 6 2001;164(5):625-631. Significant chi-square differences are represented in bold