Biotechnology is the use of living organisms to develop useful products. Modern biotechnology techniques include isolating DNA, inserting genes into vectors, and transforming host cells. Applications include producing Bt crops for pest resistance, producing vaccines and diagnosing diseases. New advances include artificial lymph nodes, non-invasive cancer detection from saliva, smart contact lenses to monitor eye pressure, and machines that can scan the liver non-invasively. Biotechnology continues to progress rapidly with applications in agriculture, medicine, and other fields.
PerkinElmer is a global leader focused on improving human and environmental health through discovery research. They provide technologies and expertise to scientists in areas like environmental monitoring, food quality, pharmaceutical development, life sciences, and diagnostics. The document provides an overview of PerkinElmer's technologies and applications in areas like high content screening, plate readers, in vivo imaging systems, and target discovery which help researchers gain insights across drug discovery, disease research, and genomics. It also includes key statistics about PerkinElmer's history, locations, patents, and the scale of samples and data they have helped analyze.
Life Technologies (now Thermo Fisher Scientific) combines next-generation sequencing, in silico gene design and synthesis, synthetic biology products, and manufacturing capabilities to form a comprehensive synthetic vaccine development workflow.
Introduction
Definition
History
Principle
Components of bioinformatics
Bioinformatics databases
Tools of bioinformatics
Applications of bioinformatics
Molecular medicine
Microbial genomics
Plant genomics
Animal genomics
Human genomics
Drug and vaccine designing
Proteomics
For studying biomolecular structures
In- silico testing
Conclusion
References
Applications of bioinformatics, main by kk sahuKAUSHAL SAHU
Introduction
Goals of Bioinformatics
Bioinformatics & Human Genome
Project
What can we do using bioinformatics ?
Applications of bioinformatics in various fields
1) Medicine
2) Evolutionary studies
3) Agriculture
4) Microbiology
5) Biotechnology
Conclusion
References
Multiplex Assays in Translational Medicine: Technologies, Applications, and F...ReportLinker.com
The development and growth of assay technologies has pushed translational medicine into a category unto itself. In a broad perspective on this field, this new report:Defines translational medicine by giving some historical background as well as providing personal definitions from experts in the field Discusses the evolution of assay technologies Reviews currently available assay technologies that apply directly to translational medicine Describes and evaluates current applications of these technologies Provides case studies of clinicians currently using this technology in their research Discusses future directions of assay technologies for translational medicine Gives input from the FDA on translation medicine and assay technologies Provides interviews from experts in the field of both translational medicine and specific assay technologies Profiles premier companies active in the field Assay technologies have been evolving since scientists first discovered they could measure glucose, insulin, and several hormones in the blood to help them diagnose disease. Early instruments such as the Ames Reflectance Meter, used for detecting glucose levels, have morphed into such sophisticated systems as flow cytometers. The Human Genome Project provided the basics for researchers to launch into the field of human genomics and they needed the tools to accomplish this. DNA microarrays allowed for massively parallel gene expression analyses. Scientists soon discovered that while the genomewide assays were extremely valuable, there were genes of interest that they had difficulty measuring when they got hundreds of data points from a microarray. Low- to mid-density assays have allowed scientists to pinpoint the genetic code for a variety of uses, from genetic heredity studies to drug metabolism and patient stratification.
The Significance of Lifescience- An In-depth Exploration.pdfhealthcare360social
Lifescience, an expansive and dynamic domain, unveils the enigmas of living organisms and their intricate connections with the environment. Its impact spans from molding pivotal medical advancements to influencing initiatives in conservation.
This document provides an overview of agrifood nanotechnology and issues related to its risk assessment and oversight. It introduces nanotechnology and describes some current and potential agrifood applications. It also discusses challenges for oversight given the diverse applications and agencies involved. While some coordinated framework is proposed based on existing laws and agencies, there are acknowledged gaps and lack of resources for adequate oversight and risk assessment of emerging nanotechnologies. More discussion is needed around governance models and public participation to help guide the responsible development of agrifood nanotechnology.
Biotechnology is the use of living organisms to develop useful products. Modern biotechnology techniques include isolating DNA, inserting genes into vectors, and transforming host cells. Applications include producing Bt crops for pest resistance, producing vaccines and diagnosing diseases. New advances include artificial lymph nodes, non-invasive cancer detection from saliva, smart contact lenses to monitor eye pressure, and machines that can scan the liver non-invasively. Biotechnology continues to progress rapidly with applications in agriculture, medicine, and other fields.
PerkinElmer is a global leader focused on improving human and environmental health through discovery research. They provide technologies and expertise to scientists in areas like environmental monitoring, food quality, pharmaceutical development, life sciences, and diagnostics. The document provides an overview of PerkinElmer's technologies and applications in areas like high content screening, plate readers, in vivo imaging systems, and target discovery which help researchers gain insights across drug discovery, disease research, and genomics. It also includes key statistics about PerkinElmer's history, locations, patents, and the scale of samples and data they have helped analyze.
Life Technologies (now Thermo Fisher Scientific) combines next-generation sequencing, in silico gene design and synthesis, synthetic biology products, and manufacturing capabilities to form a comprehensive synthetic vaccine development workflow.
Introduction
Definition
History
Principle
Components of bioinformatics
Bioinformatics databases
Tools of bioinformatics
Applications of bioinformatics
Molecular medicine
Microbial genomics
Plant genomics
Animal genomics
Human genomics
Drug and vaccine designing
Proteomics
For studying biomolecular structures
In- silico testing
Conclusion
References
Applications of bioinformatics, main by kk sahuKAUSHAL SAHU
Introduction
Goals of Bioinformatics
Bioinformatics & Human Genome
Project
What can we do using bioinformatics ?
Applications of bioinformatics in various fields
1) Medicine
2) Evolutionary studies
3) Agriculture
4) Microbiology
5) Biotechnology
Conclusion
References
Multiplex Assays in Translational Medicine: Technologies, Applications, and F...ReportLinker.com
The development and growth of assay technologies has pushed translational medicine into a category unto itself. In a broad perspective on this field, this new report:Defines translational medicine by giving some historical background as well as providing personal definitions from experts in the field Discusses the evolution of assay technologies Reviews currently available assay technologies that apply directly to translational medicine Describes and evaluates current applications of these technologies Provides case studies of clinicians currently using this technology in their research Discusses future directions of assay technologies for translational medicine Gives input from the FDA on translation medicine and assay technologies Provides interviews from experts in the field of both translational medicine and specific assay technologies Profiles premier companies active in the field Assay technologies have been evolving since scientists first discovered they could measure glucose, insulin, and several hormones in the blood to help them diagnose disease. Early instruments such as the Ames Reflectance Meter, used for detecting glucose levels, have morphed into such sophisticated systems as flow cytometers. The Human Genome Project provided the basics for researchers to launch into the field of human genomics and they needed the tools to accomplish this. DNA microarrays allowed for massively parallel gene expression analyses. Scientists soon discovered that while the genomewide assays were extremely valuable, there were genes of interest that they had difficulty measuring when they got hundreds of data points from a microarray. Low- to mid-density assays have allowed scientists to pinpoint the genetic code for a variety of uses, from genetic heredity studies to drug metabolism and patient stratification.
The Significance of Lifescience- An In-depth Exploration.pdfhealthcare360social
Lifescience, an expansive and dynamic domain, unveils the enigmas of living organisms and their intricate connections with the environment. Its impact spans from molding pivotal medical advancements to influencing initiatives in conservation.
This document provides an overview of agrifood nanotechnology and issues related to its risk assessment and oversight. It introduces nanotechnology and describes some current and potential agrifood applications. It also discusses challenges for oversight given the diverse applications and agencies involved. While some coordinated framework is proposed based on existing laws and agencies, there are acknowledged gaps and lack of resources for adequate oversight and risk assessment of emerging nanotechnologies. More discussion is needed around governance models and public participation to help guide the responsible development of agrifood nanotechnology.
How AstraZeneca is Applying AI, Imaging & Data Analytics (AI-Driven Drug Deve...Nick Brown
Keynote AI Presentation given at AI-Driven Drug Development Summit Europe on 26th April 2023 in London. Overview around how AstraZeneca has been developing AI in the past 5+ years. Predominantly focused on R&D and how we are developing digital solutions & AI for right safety and right dose. AI examples include machine learning for safety assessment, augmenting digital pathology for image quantification & segmentation, understanding more about our drugs through advanced imaging modalities and first steps in applying AI for right dose - immunogenicity, adverse events and tolerability.
Miniature Drug delivery System uses micro-fabricated devices to administer drugs to the host and has advantages over a conventional drug delivery system
A MEMS based Implantable Drug Delivery System (IDDS) is discussed. The heart of the system is an in-plane MEMS micropumps enables us to make a compact, inexpensive system. A conceptual IDDS design is proposed. This design consists of an implantable unit which houses the micropumps, electronic and power circuitry. This implantable unit is connected to a subcutaneous port via a silicone catheter. The subcutaneous port acts as a refillable reservoir. This leads to a reduction in unit volume and makes the system customizable. The IDDS pumps drug into surrounding tissue with the help of a MEMS based micropumps. Similarly Microneedles are also used in drug administration.
This report gives an overview of patenting activity around Miniature Drug Delivery System. Smart drug delivery system is used for delivering drugs to the host effectively and improves the quality of life of the patients. Patents were categorized as per key Drug Delivery administration methods, types of sensors, applications, communication techniques and analyzed for generating different trends with Patent iNSIGHT Pro.
Miniature Drug Delivery System technology has seen a consistent increase in the number of patent publications from 2008 till 2012 as the need for smart drug delivery has increase globally.
Published: Apr 30, 2013
This document provides an overview of the field of bioinformatics. It defines bioinformatics as using computational techniques to solve biological problems by analyzing large amounts of biological data like DNA sequences, amino acid sequences, and more. It discusses the need for bioinformatics due to the exponential growth of biological data from sequencing projects. Some key applications of bioinformatics mentioned include data management, knowledge discovery, drug discovery, proteomics, personalized medicine, agriculture, and its use in systems biology.
This document discusses emerging trends in biotechnology. It begins with an introduction to biotechnology and its history, including major discoveries from 1919 to 2020. It then outlines emerging trends like artificial intelligence, big data, gene editing, precision medicine, gene sequencing, biomanufacturing, bioprinting, and synthetic biology. Each trend is briefly described in 1-2 sentences. The document concludes by noting challenges in biotechnology like high costs, regulatory issues, talent shortages, and inadequate technology, but emphasizes that biotechnology advancement is crucial to address global issues in health, food, and the environment.
This document discusses emerging trends in biotechnology, including artificial intelligence, big data, gene editing, precision medicine, gene sequencing, biomanufacturing, synthetic biology, bioprinting, microfluidics, and tissue engineering. It explains how these trends are enabling biotechnology startups to develop new medical products and therapies, scale operations, drive innovation, offer personalized treatment, and optimize bioprocessing. Gene editing techniques in particular allow for targeted gene modification and applications in gene therapy and transgenic organisms.
The document discusses future trends in synthetic biology. It begins by defining synthetic biology as the application of engineering principles to biology to redesign biological systems. Some potential future trends discussed include using synthetic biology for regenerative medicine like producing personalized stem cells, making xenotransplantation a reality through CRISPR-edited pigs, and 3D bioprinting of tissues and organs. Other trends include using nanobots and RNA/DNA vaccines to treat diseases, synthesizing human chromosomes, and developing edible vaccines. While synthetic biology holds promise, risks also exist and regulations are needed to ensure safety and ethical development.
This seminar report discusses biosensors used in agriculture. It provides an overview of different types of biosensors including electrochemical, potentiometric, amperometric, calorimetric and optical biosensors. It discusses the principle of signal transduction that biosensors use to convert biological reactions into electrical signals. The report also examines the role of biosensors in agriculture for detecting crop diseases and pathogens in plants. Some advantages of biosensors include high sensitivity, selectivity and rapid response times. Potential disadvantages include susceptibility to interference and limited lifespan.
This document provides information about the "CNS Clinical Trials" conference taking place on September 16-17, 2010 in London. The conference will examine strategies for successful CNS drug development and overcoming challenges in clinical trial design, management, and recruitment. Key topics will include novel cognitive assessment methods, advances in neuroimaging, adaptive trial design, and the use of biomarkers to demonstrate early drug effects in CNS trials. Speakers will include representatives from pharmaceutical and biotechnology companies as well as academic institutions. Attendees will gain insights on improving various aspects of CNS clinical trials from development through regulatory approval. The conference also provides sponsorship and exhibition opportunities for companies to promote their products and services.
Thermo Fisher Scientific India Pvt. Ltd. (NYSE: TMO) is the world leader in serving science, with revenues of $18 billion and approximately 55,000 employees globally. Our mission through our premier brands Thermo Scientific, Applied Bio Systems, Invitrogen, Fisher Scientific and Unity Lab Services, we offer an unmatched combination of innovative is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. We offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support.
Bioinformatics issues and challanges presentation at s p collegeSKUASTKashmir
This document provides an overview of bioinformatics and some key concepts:
- It discusses the exponential growth of biological data from technologies like PCR and microarrays, and how bioinformatics is needed to analyze this data.
- Bioinformatics is defined as integrating biology and computer science to collect, analyze, and interpret large amounts of molecular-level information. It uses databases and tools to study genomes, proteins, and biological processes.
- Major databases like GenBank, EMBL, and SwissProt store DNA, RNA, protein sequences and provide access to researchers. Tools like BLAST are used to search databases and analyze sequences.
- Benefits of bioinformatics include advances in medicine, agriculture, forensics
Its my utmost belief that Kenya and other developing countries should be in the mainstream of adapting technology in excellent service delivery.
Veterinary Medicine applications of technology can improve education and service delivery.Here i highlight Informatics, Diagnostics,Biotechnology.Data analysis,Simualtion modelling and networks to outline policy changes for Kenya
mHealth Israel_Ryo Kosaka_AIST_National Institute of Advanced Industrial Scie...Levi Shapiro
Presentation by Ryo Kosaka, Senior Research Scientist, Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST). Includes an overview of priority strategies in Life Sciences and Biotech and description of the organization of the Life Sciences and Biotech department. Recent projects include a Portable System for High-Speed DNA Quantification, Application of a cell microarray chip for clinical diagnosis and single cell analysis, Safe and Secure Artificial Heart, New diagnosis for liver fibrosis utilizing glycans, AIST ventures from the department of Life Science & Biotech as well as International cooperation.
Bioinformatics requires knowledge of molecular biology, biochemistry, molecular biophysics, molecular modelling, computer science, and biostatistics. The goals of bioinformatics are to manage biological data in an easy to access way, submit new entries as they are produced, and develop tools to analyze biological data from a biological perspective. General applications of DNA data and technologies include more accurate medicine, understanding microbes to use their abilities to clean the environment and generate energy, understanding human lineage through time, making crops and animals more resistant to threats, and DNA identification for various purposes.
Predicting Drug Candidates Safety : the Role and Usage of Knowledge BasesAureus Sciences
- Aureus Sciences builds knowledge bases for predicting drug candidates' safety, focusing on areas like drug-drug interactions, safety pharmacology, and off-target effects.
- They have developed large structured databases of chemical and bioactivity information from literature and provide applications and services to analyze the data for customers in drug development.
- Their predictive models and databases have been shown to accurately predict drug interactions and off-target effects, helping customers optimize drug safety assessment.
This document provides an introduction to the field of bioinformatics. It defines bioinformatics as a branch of science that uses computer technology to analyze and integrate biological information that can be applied to gene-based drug discoveries. It discusses the emergence of bioinformatics due to the desire to understand how genetic structure affects traits. It also outlines some common applications of bioinformatics like drug design, gene therapy, and microbial genomic analysis. Finally, it provides examples of some bioinformatics tools, databases, and centers in India.
Patent Anlaysis Report - Miniature drug delivery systemsPrashant Nair
This report takes a look into the patenting activity around miniature/smart drug delivery system, uncovering the key companies, inventors, and different sub categories.
The document summarizes opportunities in the bio-medical industry in the South West region of the UK. It finds that the region has strengths in clinical research, diagnostics, medical devices, biosecurity, and bioinformatics. In particular, the region is a world leader in fields like oncology, neuroscience, and stem cell research. It also has a large presence of companies involved in manufacturing, distribution, diagnostics, and medical devices. The document analyzes opportunities in areas like nanotechnology applications, diagnostics, biosecurity, and bioinformatics and provides profiles of leading companies in each area. However, it notes regulatory and market uncertainties for some opportunities.
An Introduction to Bioinformatics
Drexel University INFO648-900-200915
A Presentation of Health Informatics Group 5
Cecilia Vernes
Joel Abueg
Kadodjomon Yeo
Sharon McDowell Hall
Terrence Hughes
Nucleic Acid Aptamers for Diagnostics and Therapeutics: Global MarketsReportsnReports
This report analyzes the global market for nucleic acid aptamers used for diagnostics and therapeutics. It provides an overview of aptamer applications, analyzes market trends from 2011-2017, and identifies high-growth segments. The 138-page report was published in October 2012 and costs $4,850 for a single-user license. It examines technology growth opportunities for aptamers and profiles major industry players.
What You May Have Missed at AACC 2018 White Paper - Kalorama InformationBruce Carlson
Each year the American Association for Clinical Chemistry draws tens of thousands of lab professionals and in vitro diagnostic vendors to one place. Kalorama Information was there and noted major developments at the meeting in this White Paper. Major themes of scientific sessions, new products from lab and IVD vendors are included.
Digital Biology: Evolution, Components, Applications, and More | The Lifescie...The Lifesciences Magazine
Applications of Digital Biology: 1. Genomics and Personalized Medicine 2. Drug Discovery and Development 3. Biotechnology and Agriculture 4. Environmental Monitoring
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How AstraZeneca is Applying AI, Imaging & Data Analytics (AI-Driven Drug Deve...Nick Brown
Keynote AI Presentation given at AI-Driven Drug Development Summit Europe on 26th April 2023 in London. Overview around how AstraZeneca has been developing AI in the past 5+ years. Predominantly focused on R&D and how we are developing digital solutions & AI for right safety and right dose. AI examples include machine learning for safety assessment, augmenting digital pathology for image quantification & segmentation, understanding more about our drugs through advanced imaging modalities and first steps in applying AI for right dose - immunogenicity, adverse events and tolerability.
Miniature Drug delivery System uses micro-fabricated devices to administer drugs to the host and has advantages over a conventional drug delivery system
A MEMS based Implantable Drug Delivery System (IDDS) is discussed. The heart of the system is an in-plane MEMS micropumps enables us to make a compact, inexpensive system. A conceptual IDDS design is proposed. This design consists of an implantable unit which houses the micropumps, electronic and power circuitry. This implantable unit is connected to a subcutaneous port via a silicone catheter. The subcutaneous port acts as a refillable reservoir. This leads to a reduction in unit volume and makes the system customizable. The IDDS pumps drug into surrounding tissue with the help of a MEMS based micropumps. Similarly Microneedles are also used in drug administration.
This report gives an overview of patenting activity around Miniature Drug Delivery System. Smart drug delivery system is used for delivering drugs to the host effectively and improves the quality of life of the patients. Patents were categorized as per key Drug Delivery administration methods, types of sensors, applications, communication techniques and analyzed for generating different trends with Patent iNSIGHT Pro.
Miniature Drug Delivery System technology has seen a consistent increase in the number of patent publications from 2008 till 2012 as the need for smart drug delivery has increase globally.
Published: Apr 30, 2013
This document provides an overview of the field of bioinformatics. It defines bioinformatics as using computational techniques to solve biological problems by analyzing large amounts of biological data like DNA sequences, amino acid sequences, and more. It discusses the need for bioinformatics due to the exponential growth of biological data from sequencing projects. Some key applications of bioinformatics mentioned include data management, knowledge discovery, drug discovery, proteomics, personalized medicine, agriculture, and its use in systems biology.
This document discusses emerging trends in biotechnology. It begins with an introduction to biotechnology and its history, including major discoveries from 1919 to 2020. It then outlines emerging trends like artificial intelligence, big data, gene editing, precision medicine, gene sequencing, biomanufacturing, bioprinting, and synthetic biology. Each trend is briefly described in 1-2 sentences. The document concludes by noting challenges in biotechnology like high costs, regulatory issues, talent shortages, and inadequate technology, but emphasizes that biotechnology advancement is crucial to address global issues in health, food, and the environment.
This document discusses emerging trends in biotechnology, including artificial intelligence, big data, gene editing, precision medicine, gene sequencing, biomanufacturing, synthetic biology, bioprinting, microfluidics, and tissue engineering. It explains how these trends are enabling biotechnology startups to develop new medical products and therapies, scale operations, drive innovation, offer personalized treatment, and optimize bioprocessing. Gene editing techniques in particular allow for targeted gene modification and applications in gene therapy and transgenic organisms.
The document discusses future trends in synthetic biology. It begins by defining synthetic biology as the application of engineering principles to biology to redesign biological systems. Some potential future trends discussed include using synthetic biology for regenerative medicine like producing personalized stem cells, making xenotransplantation a reality through CRISPR-edited pigs, and 3D bioprinting of tissues and organs. Other trends include using nanobots and RNA/DNA vaccines to treat diseases, synthesizing human chromosomes, and developing edible vaccines. While synthetic biology holds promise, risks also exist and regulations are needed to ensure safety and ethical development.
This seminar report discusses biosensors used in agriculture. It provides an overview of different types of biosensors including electrochemical, potentiometric, amperometric, calorimetric and optical biosensors. It discusses the principle of signal transduction that biosensors use to convert biological reactions into electrical signals. The report also examines the role of biosensors in agriculture for detecting crop diseases and pathogens in plants. Some advantages of biosensors include high sensitivity, selectivity and rapid response times. Potential disadvantages include susceptibility to interference and limited lifespan.
This document provides information about the "CNS Clinical Trials" conference taking place on September 16-17, 2010 in London. The conference will examine strategies for successful CNS drug development and overcoming challenges in clinical trial design, management, and recruitment. Key topics will include novel cognitive assessment methods, advances in neuroimaging, adaptive trial design, and the use of biomarkers to demonstrate early drug effects in CNS trials. Speakers will include representatives from pharmaceutical and biotechnology companies as well as academic institutions. Attendees will gain insights on improving various aspects of CNS clinical trials from development through regulatory approval. The conference also provides sponsorship and exhibition opportunities for companies to promote their products and services.
Thermo Fisher Scientific India Pvt. Ltd. (NYSE: TMO) is the world leader in serving science, with revenues of $18 billion and approximately 55,000 employees globally. Our mission through our premier brands Thermo Scientific, Applied Bio Systems, Invitrogen, Fisher Scientific and Unity Lab Services, we offer an unmatched combination of innovative is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. We offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support.
Bioinformatics issues and challanges presentation at s p collegeSKUASTKashmir
This document provides an overview of bioinformatics and some key concepts:
- It discusses the exponential growth of biological data from technologies like PCR and microarrays, and how bioinformatics is needed to analyze this data.
- Bioinformatics is defined as integrating biology and computer science to collect, analyze, and interpret large amounts of molecular-level information. It uses databases and tools to study genomes, proteins, and biological processes.
- Major databases like GenBank, EMBL, and SwissProt store DNA, RNA, protein sequences and provide access to researchers. Tools like BLAST are used to search databases and analyze sequences.
- Benefits of bioinformatics include advances in medicine, agriculture, forensics
Its my utmost belief that Kenya and other developing countries should be in the mainstream of adapting technology in excellent service delivery.
Veterinary Medicine applications of technology can improve education and service delivery.Here i highlight Informatics, Diagnostics,Biotechnology.Data analysis,Simualtion modelling and networks to outline policy changes for Kenya
mHealth Israel_Ryo Kosaka_AIST_National Institute of Advanced Industrial Scie...Levi Shapiro
Presentation by Ryo Kosaka, Senior Research Scientist, Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST). Includes an overview of priority strategies in Life Sciences and Biotech and description of the organization of the Life Sciences and Biotech department. Recent projects include a Portable System for High-Speed DNA Quantification, Application of a cell microarray chip for clinical diagnosis and single cell analysis, Safe and Secure Artificial Heart, New diagnosis for liver fibrosis utilizing glycans, AIST ventures from the department of Life Science & Biotech as well as International cooperation.
Bioinformatics requires knowledge of molecular biology, biochemistry, molecular biophysics, molecular modelling, computer science, and biostatistics. The goals of bioinformatics are to manage biological data in an easy to access way, submit new entries as they are produced, and develop tools to analyze biological data from a biological perspective. General applications of DNA data and technologies include more accurate medicine, understanding microbes to use their abilities to clean the environment and generate energy, understanding human lineage through time, making crops and animals more resistant to threats, and DNA identification for various purposes.
Predicting Drug Candidates Safety : the Role and Usage of Knowledge BasesAureus Sciences
- Aureus Sciences builds knowledge bases for predicting drug candidates' safety, focusing on areas like drug-drug interactions, safety pharmacology, and off-target effects.
- They have developed large structured databases of chemical and bioactivity information from literature and provide applications and services to analyze the data for customers in drug development.
- Their predictive models and databases have been shown to accurately predict drug interactions and off-target effects, helping customers optimize drug safety assessment.
This document provides an introduction to the field of bioinformatics. It defines bioinformatics as a branch of science that uses computer technology to analyze and integrate biological information that can be applied to gene-based drug discoveries. It discusses the emergence of bioinformatics due to the desire to understand how genetic structure affects traits. It also outlines some common applications of bioinformatics like drug design, gene therapy, and microbial genomic analysis. Finally, it provides examples of some bioinformatics tools, databases, and centers in India.
Patent Anlaysis Report - Miniature drug delivery systemsPrashant Nair
This report takes a look into the patenting activity around miniature/smart drug delivery system, uncovering the key companies, inventors, and different sub categories.
The document summarizes opportunities in the bio-medical industry in the South West region of the UK. It finds that the region has strengths in clinical research, diagnostics, medical devices, biosecurity, and bioinformatics. In particular, the region is a world leader in fields like oncology, neuroscience, and stem cell research. It also has a large presence of companies involved in manufacturing, distribution, diagnostics, and medical devices. The document analyzes opportunities in areas like nanotechnology applications, diagnostics, biosecurity, and bioinformatics and provides profiles of leading companies in each area. However, it notes regulatory and market uncertainties for some opportunities.
An Introduction to Bioinformatics
Drexel University INFO648-900-200915
A Presentation of Health Informatics Group 5
Cecilia Vernes
Joel Abueg
Kadodjomon Yeo
Sharon McDowell Hall
Terrence Hughes
Nucleic Acid Aptamers for Diagnostics and Therapeutics: Global MarketsReportsnReports
This report analyzes the global market for nucleic acid aptamers used for diagnostics and therapeutics. It provides an overview of aptamer applications, analyzes market trends from 2011-2017, and identifies high-growth segments. The 138-page report was published in October 2012 and costs $4,850 for a single-user license. It examines technology growth opportunities for aptamers and profiles major industry players.
What You May Have Missed at AACC 2018 White Paper - Kalorama InformationBruce Carlson
Each year the American Association for Clinical Chemistry draws tens of thousands of lab professionals and in vitro diagnostic vendors to one place. Kalorama Information was there and noted major developments at the meeting in this White Paper. Major themes of scientific sessions, new products from lab and IVD vendors are included.
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- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
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Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
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The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
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Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
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• Building trust with communities online and offline
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• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
share - Lions, tigers, AI and health misinformation, oh my!.pptx
Applied Biosystems: Products, Technologies, Future Innovations, Impact on Genomics and Biotechnology | The Lifesciences Magazine
1. Applied Biosystems: Revolutionizing
Life Sciences and Biotechnology
Source-Thermo-Fisher-Scientific
Applied Biosystems, a renowned name in the life sciences and biotechnology industry, has been
at the forefront of innovation for decades. Specializing in the development of cutting-edge
instruments, reagents, and software for molecular biology research, Applied Biosystems has
significantly advanced the fields of genomics, proteomics, and beyond. This article explores the
history, key products, and contributions of Applied Biosystems to the scientific community,
highlighting its impact on modern biotechnology.
A Brief History of Applied Biosystems
1. Founding and Early Innovations
Applied Biosystems was founded in 1981 by Dr. Sam Eletr and Dr. Andre Marion, both pioneers
in the field of biotechnology. The company’s mission was to create tools that would empower
scientists to explore the complexities of biological systems. Early on, Applied Biosystems
focused on developing instruments for DNA sequencing and synthesis, which quickly became
essential tools in molecular biology laboratories worldwide.
2. Acquisition by Perkin-Elmer and Subsequent Developments
In 1983, Applied Biosystems was acquired by Perkin-Elmer Corporation, which provided the
resources and support needed to expand its product line and reach. This acquisition led to
2. significant advancements in automated DNA sequencing technology, contributing to major
scientific milestones such as the Human Genome Project.
3. Thermo Fisher Scientific Merger
Source-Tech-Startups
In 2008, Applied Biosystems merged with Invitrogen Corporation, forming Life Technologies.
This entity was later acquired by Thermo Fisher Scientific in 2014, integrating Applied
Biosystems into a broader portfolio of life sciences products and services. This merger has further
enhanced the company’s ability to deliver comprehensive solutions to the scientific community.
Key Products and Technologies
Applied Biosystems is known for its wide range of products that cater to various aspects of
molecular biology research. Here, we highlight some of the most influential products and
technologies developed by Applied Biosystems.
1. DNA Sequencing Instruments
Applied Biosystems revolutionized DNA sequencing with the introduction of automated
sequencing instruments. The ABI Prism™ series, including the ABI 310, 3100, and 3730 Genetic
Analyzers, set new standards for accuracy and efficiency in sequencing. These instruments
played a crucial role in projects like the Human Genome Project, providing the high-throughput
capabilities needed for large-scale sequencing efforts.
2. Real-Time PCR Systems
3. Real-Time PCR (Polymerase Chain Reaction) systems are another cornerstone of Applied
Biosystems’ product line. The ABI PRISM™ 7500, 7900HT, and StepOnePlus™ Real-Time
PCR Systems offer precise quantification of nucleic acids, enabling applications in gene
expression analysis, genotyping, and pathogen detection. These instruments are widely used in
research, clinical diagnostics, and forensic science.
3. Next-Generation Sequencing (NGS)
Source-Crown-Bioscience-Blog
Applied Biosystems has also made significant strides in Next-Generation Sequencing (NGS)
technology. The Ion Torrent™ platform, acquired and integrated into Applied Biosystems,
provides rapid and cost-effective sequencing solutions. The Ion Proton™ and Ion S5™ systems
have made high-throughput sequencing accessible to a broader range of laboratories, facilitating
advancements in personalized medicine and genomics research.
4. Capillary Electrophoresis
Capillary electrophoresis (CE) systems, such as the 3500 Genetic Analyzer, are vital for DNA
fragment analysis, including Sanger sequencing and fragment length polymorphism (FLP)
analysis. These systems are known for their high resolution and accuracy, making them
indispensable tools in genetic research and clinical diagnostics.
5. Applied Biosystems™ Reagents and Consumables
In addition to instruments, Applied Biosystems offers a comprehensive range of reagents and
consumables designed to work seamlessly with their systems. These include TaqMan™ probes,
SYBR™ Green master mixes, and various kits for sample preparation and nucleic acid
purification. These high-quality reagents ensure reliable and reproducible results, critical for
scientific research.
4. Impact on Genomics and Biotechnology
1. Human Genome Project
One of the most significant contributions of Applied Biosystems was its involvement in the
Human Genome Project. The automated DNA sequencers developed by the company were
instrumental in mapping the human genome, a milestone that has paved the way for numerous
advances in medicine, genetics, and biology.
2. Personalized Medicine
The advent of Applied Biosystems’ sequencing and PCR technologies has been a driving force
behind the development of personalized medicine. By enabling detailed genetic analysis, these
technologies allow for the identification of genetic variations associated with diseases, leading to
more targeted and effective treatments tailored to individual patients.
3. Forensic Science
Applied Biosystems has also revolutionized forensic science with its DNA analysis technologies.
The ability to accurately analyze and compare DNA samples has become a cornerstone of
modern forensic investigations, aiding in criminal justice and paternity testing.
4. Agricultural Biotechnology
In agriculture, Applied Biosystems’ technologies have facilitated advancements in plant and
animal genomics. By enabling the identification of genetic traits associated with desirable
characteristics, these technologies have contributed to the development of improved crop
varieties and livestock breeds.
Future Directions and Innovations
1. Advancements in Sequencing Technologies
Applied Biosystems continues to innovate in the field of sequencing technologies. Future
developments are expected to focus on increasing the speed, accuracy, and affordability of
sequencing, making it even more accessible for routine clinical use and research applications.
2. Integration with Bioinformatics
5. Source-UEF-Connect
As the amount of genomic data generated by sequencing technologies grows, the integration of
bioinformatics tools becomes increasingly important. Applied Biosystems is likely to invest in
developing software and analytical platforms that can efficiently manage and interpret large
datasets, providing researchers with actionable insights.
3. Expansion into New Markets
With the ongoing advancements in molecular biology, Applied Biosystems is poised to expand
into new markets such as synthetic biology, environmental monitoring, and infectious disease
surveillance. These areas hold significant potential for growth and innovation, leveraging the
company’s expertise in genetic analysis and instrumentation.
Conclusion
Applied Biosystems has been a pioneering force in the life sciences and biotechnology industry
for over four decades. Its innovative products and technologies have transformed various fields,
from genomics and personalized medicine to forensic science and agricultural biotechnology. As
the company continues to innovate and expand its offerings, its impact on scientific research and
healthcare is set to grow even further. Through its commitment to advancing scientific discovery,
Applied Biosystems remains a cornerstone of modern biotechnology, empowering researchers
and clinicians worldwide to explore the complexities of life and improve human health.