This document outlines how to setup a sustainable data science business function. It recommends: 1) Starting with a small, focused team of 2-6 generalist data scientists; 2) Clearly defining projects with goals, specs, progress meetings and knowledge sharing; 3) Systematizing the data pipeline and analyses with source control, code reviews and refactoring; 4) Ensuring effective communication with daily stand-ups, a task schedule, centralized communication tools and allowing time for focused work. The key is to define problems, access data, embrace failure, automate where possible and maintain an ongoing development cycle with corporate sponsorship and strong internal/external communication.