This study evaluated patient satisfaction with pharmacy services provided through mail-order, independent, and chain pharmacies among 184 HIV patients. Patients were most satisfied with services from independent pharmacies and least satisfied with mail-order pharmacies. Higher dissatisfaction with mail-order was associated with extra medications left over when medications were stopped and delays receiving new prescriptions. Higher dissatisfaction with independent and chain pharmacies correlated with more unscheduled doctor's visits and emergency room visits, respectively, for medication-related issues.