This document discusses the concept of sensemaking, which refers to how people construct plausible interpretations when facing ambiguous situations. Sensemaking is prominent in conditions of uncertainty, unfamiliarity, disruption, or distributed action across multiple actors. It involves shaping a frame of reference, extracting cues, and constructing a gestalt or narrative to impose order. Context, prior experiences, and interests influence this process. The document provides examples of sensemaking around crises like mad cow disease and emerging diseases. It also discusses how information systems can support sensemaking during disasters and uncertainty.