Ancestry DNA testing utilizes advanced DNA science to predict a person's genetic ethnicity and help them find new family connections by mapping their ethnicity over multiple generations. The test provides insight into what regions of Europe a person's ancestors may have come from or if they have East Asian heritage. It can also help identify relationships with unknown relatives. There are four categories of ancestral DNA testing: DNA origins, GPS origins, DNA paternal lineage testing, and DNA maternal lineage testing. DNA origins testing provides understanding of a person's genetic ancestors and origins, while GPS origins more precisely pinpoints the locations where ancestral groups met. Paternal and maternal lineage testing examines the DNA passed down unchanged from fathers to sons or mothers to children to trace direct ancestry lines far
Affordable and Best DNA Testing in India.DNA Forensics Laboratory offers fully accredited DNA testing services anywhere in the India and internationally with affordable cost and 100% accuracy.
What family question do you need answered? It may be in your DNA! Choose the most appropriate category below to learn more, then call your local ANY LAB TEST WACO location for assistance.
Affordable and Best DNA Testing in India.DNA Forensics Laboratory offers fully accredited DNA testing services anywhere in the India and internationally with affordable cost and 100% accuracy.
What family question do you need answered? It may be in your DNA! Choose the most appropriate category below to learn more, then call your local ANY LAB TEST WACO location for assistance.
Genealogists for hundreds of years have relied on records and pedigrees to trace family lines. More than one has run into a brick wall, discovered an error from a prior researcher, or simply had a gut feeling that something wasn’t adding up. Until recently there was no way to help confirm your paper trails or even those hunches you might have had. Now, with affordable DNA testing, many genealogists are discovering this new tool in their kit. Unfortunately, most are not sure what they should do with it. In this lecture you will learn the basics of genetics, how DNA can help you, and the tests available to you.
Parental testing is considered one of the best ways to establish a biological parent child relation between individuals
Do you believe that your partner is currently
being unfaithful?
As you study DNA, you find that every persons DNA is different from.docxlauricesatu
As you study DNA, you find that every person's DNA is different from another's. Identical twins are the only people whose DNA is the same. Consider your parents and your siblings. Even though your brother and your sister have the same parents, it is unlikely that you look exactly like them unless you are identical twins. You may have common features, and you will all share common DNA among yourselves, but only identical twins will have the exact same DNA. DNA testing is used for many reasons such as the following:
Identify potential suspects whose DNA may match evidence left at crime scenes
Exonerate persons wrongly accused
Match organ donors
Assignment Guidelines
Address the following in 4–5 pages:
In your first case, you have been asked to list and explain the steps that you would use to identify and analyze DNA from a person who has been in prison for 10 years. The results of your test may exonerate the person.
Once the physical evidence has been delivered to the forensics lab, what is the process of identifying DNA? Be specific, and explain in detail.
Consider that the evidence is over 10-years old.
Once the DNA evidence has been identified, what is the process of analyzing the DNA? Be specific, and explain in detail.
What challenges exist that can make your analysis inadmissible in court? Explain.
How are tissue matches made? Explain.
Why is it important to utilize different DNA testing methods? Explain.
Why is it that some methods may be preferred over others? Explain.
Other than forensic uses, DNA testing is essential in paternity testing.
What are the steps used to carry out a paternity test? Explain in detail.
Why might the results of a paternity test be significant in a court case? Explain.
.
As you study DNA, you find that every persons DNA is different from.docxcargillfilberto
As you study DNA, you find that every person's DNA is different from another's. Identical twins are the only people whose DNA is the same. Consider your parents and your siblings. Even though your brother and your sister have the same parents, it is unlikely that you look exactly like them unless you are identical twins. You may have common features, and you will all share common DNA among yourselves, but only identical twins will have the exact same DNA. DNA testing is used for many reasons, such as the following:
Identify potential suspects whose DNA may match evidence left at crime scenes
Exonerate persons wrongly accused
Match organ donors
Assignment Guidelines
Address the following in 4–5 pages:
In your first case, you have been asked to list and explain the steps that you would use to identify and analyze DNA from a person who has been in prison for 10 years. The results of your test may exonerate the person.
Once the physical evidence has been delivered to the forensics lab, what is the process of identifying DNA? Be specific, and explain in detail.
Consider that the evidence is over 10 years old.
Once the DNA evidence has been identified, what is the process of analyzing the DNA? Be specific, and explain in detail.
What challenges exist that can make your analysis inadmissible in court? Explain.
How are tissue matches made? Explain.
Why is it important to utilize different DNA testing methods? Explain.
Why is it that some methods may be preferred over others? Explain.
Other than forensic uses, DNA testing is essential in paternity testing.
What are the steps used to carry out a paternity test? Explain in detail.
Why might the results of a paternity test be significant in a court case? Explain.
.
The methods for producing a DNA profile were developed by Alec Jeffreys and his team in 1985. Jefferys discovered that an unknown sample of DNA such as blood, hair, saliva, or semen could be analyzed and a unique DNA pattern/profile could be developed.
DNA analysis was first discovered, a process called Restriction Fragment Length Polymorphism (RFLP) was used to analyze
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Genealogists for hundreds of years have relied on records and pedigrees to trace family lines. More than one has run into a brick wall, discovered an error from a prior researcher, or simply had a gut feeling that something wasn’t adding up. Until recently there was no way to help confirm your paper trails or even those hunches you might have had. Now, with affordable DNA testing, many genealogists are discovering this new tool in their kit. Unfortunately, most are not sure what they should do with it. In this lecture you will learn the basics of genetics, how DNA can help you, and the tests available to you.
Parental testing is considered one of the best ways to establish a biological parent child relation between individuals
Do you believe that your partner is currently
being unfaithful?
As you study DNA, you find that every persons DNA is different from.docxlauricesatu
As you study DNA, you find that every person's DNA is different from another's. Identical twins are the only people whose DNA is the same. Consider your parents and your siblings. Even though your brother and your sister have the same parents, it is unlikely that you look exactly like them unless you are identical twins. You may have common features, and you will all share common DNA among yourselves, but only identical twins will have the exact same DNA. DNA testing is used for many reasons such as the following:
Identify potential suspects whose DNA may match evidence left at crime scenes
Exonerate persons wrongly accused
Match organ donors
Assignment Guidelines
Address the following in 4–5 pages:
In your first case, you have been asked to list and explain the steps that you would use to identify and analyze DNA from a person who has been in prison for 10 years. The results of your test may exonerate the person.
Once the physical evidence has been delivered to the forensics lab, what is the process of identifying DNA? Be specific, and explain in detail.
Consider that the evidence is over 10-years old.
Once the DNA evidence has been identified, what is the process of analyzing the DNA? Be specific, and explain in detail.
What challenges exist that can make your analysis inadmissible in court? Explain.
How are tissue matches made? Explain.
Why is it important to utilize different DNA testing methods? Explain.
Why is it that some methods may be preferred over others? Explain.
Other than forensic uses, DNA testing is essential in paternity testing.
What are the steps used to carry out a paternity test? Explain in detail.
Why might the results of a paternity test be significant in a court case? Explain.
.
As you study DNA, you find that every persons DNA is different from.docxcargillfilberto
As you study DNA, you find that every person's DNA is different from another's. Identical twins are the only people whose DNA is the same. Consider your parents and your siblings. Even though your brother and your sister have the same parents, it is unlikely that you look exactly like them unless you are identical twins. You may have common features, and you will all share common DNA among yourselves, but only identical twins will have the exact same DNA. DNA testing is used for many reasons, such as the following:
Identify potential suspects whose DNA may match evidence left at crime scenes
Exonerate persons wrongly accused
Match organ donors
Assignment Guidelines
Address the following in 4–5 pages:
In your first case, you have been asked to list and explain the steps that you would use to identify and analyze DNA from a person who has been in prison for 10 years. The results of your test may exonerate the person.
Once the physical evidence has been delivered to the forensics lab, what is the process of identifying DNA? Be specific, and explain in detail.
Consider that the evidence is over 10 years old.
Once the DNA evidence has been identified, what is the process of analyzing the DNA? Be specific, and explain in detail.
What challenges exist that can make your analysis inadmissible in court? Explain.
How are tissue matches made? Explain.
Why is it important to utilize different DNA testing methods? Explain.
Why is it that some methods may be preferred over others? Explain.
Other than forensic uses, DNA testing is essential in paternity testing.
What are the steps used to carry out a paternity test? Explain in detail.
Why might the results of a paternity test be significant in a court case? Explain.
.
The methods for producing a DNA profile were developed by Alec Jeffreys and his team in 1985. Jefferys discovered that an unknown sample of DNA such as blood, hair, saliva, or semen could be analyzed and a unique DNA pattern/profile could be developed.
DNA analysis was first discovered, a process called Restriction Fragment Length Polymorphism (RFLP) was used to analyze
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Ancestry dna test
1. Ancestry DNA Test
DNA Diagnostics and Genetic Center
DNA Center India | DNA Testing Services
www.dnacenter.in | +91 7533008488 | info@dnacenter.in
2. What is Ancestry DNA Test?
• Ancestry DNA is a new DNA testing service that utilizes
some of the latest autosomal testing technology to
revolutionize the way you discover your family history. This
service utilizes advanced DNA science to predict your
genetic ethnicity and help you find new family connections.
It maps ethnicity going back multiple generations and
provides insight into such possibilities as: what region of
Europe are my ancestors from, or am I likely to have East
Asian heritage? Ancestry DNA Test can also help identify
relationships with unknown relatives through a dynamic list
of possible DNA member matches.
www.dnacenter.in | +91 7533008488 | info@dnacenter.in
3. Why Ancestry DNA Test?
• Your Ancestry DNA results include information about your
genetic ethnicity estimates and identifies potential DNA
matches, linking you to others who have taken the Ancestry
DNA test. Your results are a great starting point for more
family history research, and it can also be a way to dig even
deeper into the research you've already done.
• There are four categories in the ancestral DNA testing and
you could choose as per your requirement:
• DNA origins
• GPS Origins ancestral DNA test
• DNA Paternal lineage testing
• DNA Maternal lineage testing
www.dnacenter.in | +91 7533008488 | info@dnacenter.in
4. DNA & GPS Origins ancestral DNA test
• DNA Origins: As the name suggests, this test helps you to find your
origin. DNA Origin test is for you if you want to know more about
your roots. This test links you to your remote genealogical pre-
history and ancestors. It’s human propensity to be inquisitive. Here
the question is about your own origin. This test provides you a
better understanding of your genetic ancestors and gives you a
clear picture of your origin. This test defines your bio-geographic
ancestors.
• GPS Origins :The GPS origins ancestry DNA test combines the latest
genetic research with a new technique to point out more precisely
from where your history began. The traditional DNA test never
pinpointed your ethnicity. It was more general rather than specific.
This new GPS Origins test indicates the exact location where groups
of your ancestors from different cultures met.
www.dnacenter.in | +91 7533008488 | info@dnacenter.in
5. DNA Paternal & Maternal lineage
testing
• DNA Paternal lineage testing: DNA Ancestral origin Paternal lineage test is
based on the fact that the DNA is passed on from the father to the son
unaltered. It remains so for many generations. By examining the DNA our
history as far as our ancestors could be traced. Here our ancestors mean
the people who populated the earth initially. It is feasible to perform a
DNA Paternal Lineage Testing tracking direct male ancestry by scrutinizing
the Y chromosome.
• DNA Maternal Lineage Testing: This test is based on the scientific fact that
DNA is passed down to several generations without being altered. Here we
are talking about the DNA that is passed on from the mother to the child.
By scrutinizing the samples of DNA you could find out the maternal history
of a individual far back to the descendants that populated the earth
primarily.
www.dnacenter.in | +91 7533008488 | info@dnacenter.in
Please feel free to call our Executive for any further communication at +91 7533008488.