A 66-year-old female presented with severe crushing chest pain for 2 hours. An ECG showed ST elevation and she was diagnosed with an anterior STEMI. Due to her aspirin allergy, doctors considered performing percutaneous coronary intervention (PCI) with either balloon angioplasty or a drug-eluting stent. During the procedure, the left coronary artery (LCA) was found to originate from the right coronary artery (RCA), a rare condition. The aberrant LCA was successfully treated with balloon angioplasty and a drug-eluting stent, which the doctors believe to be the first reported case of primary PCI for an aberrant LCA arising from the RCA.