AlPiDarko Introduction
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Al Pi Darko is a strategy for parents and teachers, empowering them to help their children reach their potential.
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GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort. Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
What are the different types of Dental implants.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
DECLARATION OF HELSINKI - History and principles
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
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AlPiDarko Introduction
- 1. THE AL PI DARKO PROGRAMME This Powerpoint Presentation and all its component sections are subject to copyright, which will be strictly enforced against any unauthorized publication breaches thereof in whole or part. APD
- 2. CHANGE THE ENVIRONMENT, CHANGE THE CHILD
- 9. Do these phrases sound familiar? “ How many times do I have to tell you?” “ I’ll hit you harder next time!” “ OK, £10 this time – but no more next time!”
Editor's Notes
- 1. This is the basis of the APD Programme – any change we wish to bring about has to start with a change in the environment. This is instigated by a change in ourselves – in our behaviour, reaction, response, or indeed in a physical change of environment. The APD Programme lea ds the participant to an understanding that all behaviour is purposive and we can, through a modification of all of the above, help a child to find his place positively and help him build his self esteem. The participant is then encouraged to “try it out” immediately and report back to the group leader by means of a journal. 2. The APD Programme is about training oneself to observe behaviour and respond to it through a different lens.
- APD is an holistic approach to understanding children’s behaviour and learning patterns. In order to reach the child and understand him emotionally, psychologically and intellectually and be able to both form a relationship with him and help him reach his potential, we have to understand these 2 important sides. Having one without the other is not getting the full picture. The behaviour methodology is based on the work of Rudolf Dreikurs; The Learning Styles approach is based on the work of Barbara Prashnig.
- These are some of the issues in education that APD deals with. Each can be dealt with independently; the whole programme – 6 sessions – deals with all of these.
- These are some of characteristics of Al Pi Darko – of the programme itself and of the outcomes.
- AP D intro duces learning style preferences, using a Learning Style Analysis subsequenetly the reports from this as the framework for teachers to plan their teaching and learning effectively, reaching all learners – and for parents to create the right environment for their children to learn in.
- Certain behaviour can be interpreted in the paradigm of a power struggle (there are 3 further paradigms of interpretation in this session). Once we have identified WHY a child is behaving in a certain way, we can learn how to really deal with the situation This is just one summary of how to build self esteem and effectively manage behaviour within a specific behavioural context.
- Respect is reflective – hence the title design of all the slides in this section. Once this has been established and adults have the correct framework of rights and responsibilities in instilling and commanding respect, the APD Programme moves on to showing how to set – and keep – boundaries and establish routine.
- Discipline systems based on reward and punishment often disintegrate into threats and bribes. Parents and teachers can revolutionise their discipline systems by recognising the limitations of punitive systems and replace them with a far more effective system.