This document discusses drug addiction and its effects. It addresses what drugs are, different categories of drugs, what addiction is, risk factors for drug usage, and how drugs affect the brain. Specific drugs discussed include heroin, cocaine, methamphetamine, marijuana, alcohol and crack. The document also covers signs of alcoholism, rehabilitation options like 12-step programs and alternative treatments. It concludes that drug addiction is a serious problem that needs to be addressed and prevention through abstinence is important.
This document discusses domestic violence, including what it is, causes, signs, different types of abuse (physical, emotional, economic, etc.), statistics, myths, and how to get help. It provides information on teen dating abuse versus domestic violence, the power and control wheel, excuses abusers use, and risks of staying in an abusive relationship like injury or death. Organizations that help victims of domestic violence are mentioned. The presentation would apply this information with slides, pictures, videos and an activity to raise awareness about domestic violence and how others can help.
Guy Winch presented on the relationship between mind and body. He discussed how ignoring emotional pain and telling people to "just walk it off" can be harmful to their well-being. Loneliness and failure can negatively impact health if not properly addressed. Winch suggested using techniques like distraction and mantras to help revive self-esteem and cope with difficult emotions in a healthy way. Maintaining emotional wellness is important for overall health.
Mississippi could become the only state without an abortion clinic as the state's last clinic fights to stay open. The clinic filed a lawsuit to block a new law that requires its doctors to obtain admitting privileges at local hospitals, a requirement that clinic supporters say is meant to shut it down.
The document is a collection of 20 image links from various online sources. The images depict subjects such as famous people, film equipment, technology products, illustrations, and stock photography. There is no other accompanying text.
The document discusses arguments for and against the use of marijuana. It presents reasons why people smoke weed, such as for social or medicinal purposes, and examines whether its use is morally acceptable. The document also considers whether marijuana should be legalized and includes pictures related to drug addiction and marijuana use.
This document provides an overview of domestic violence. It defines domestic violence as abuse between intimate partners or family members that can be physical, sexual, emotional or economic. Statistics are given showing that millions of women are abused each year and over 1,500 domestic violence related deaths occur annually, mostly among women. Teen dating abuse is discussed as a precursor to domestic violence. Common types of abuse and myths about domestic violence are outlined. Signs of being in an abusive relationship and barriers to leaving are explored. Resources for victims seeking help are provided.
This document appears to be a resume or profile for Adrienne Grimes, a native of Washington D.C. who studied Media Communications at Full Sail University and Information Systems at University of Maryland Baltimore County. She has worked for the Department of Social Services and the Comptroller of the Currency. Her goal is to obtain an internship at a local broadcast station. She highlights communication, teamwork, and problem solving as strengths.
This document discusses domestic violence, including what it is, causes, signs, different types of abuse (physical, emotional, economic, etc.), statistics, myths, and how to get help. It provides information on teen dating abuse versus domestic violence, the power and control wheel, excuses abusers use, and risks of staying in an abusive relationship like injury or death. Organizations that help victims of domestic violence are mentioned. The presentation would apply this information with slides, pictures, videos and an activity to raise awareness about domestic violence and how others can help.
Guy Winch presented on the relationship between mind and body. He discussed how ignoring emotional pain and telling people to "just walk it off" can be harmful to their well-being. Loneliness and failure can negatively impact health if not properly addressed. Winch suggested using techniques like distraction and mantras to help revive self-esteem and cope with difficult emotions in a healthy way. Maintaining emotional wellness is important for overall health.
Mississippi could become the only state without an abortion clinic as the state's last clinic fights to stay open. The clinic filed a lawsuit to block a new law that requires its doctors to obtain admitting privileges at local hospitals, a requirement that clinic supporters say is meant to shut it down.
The document is a collection of 20 image links from various online sources. The images depict subjects such as famous people, film equipment, technology products, illustrations, and stock photography. There is no other accompanying text.
The document discusses arguments for and against the use of marijuana. It presents reasons why people smoke weed, such as for social or medicinal purposes, and examines whether its use is morally acceptable. The document also considers whether marijuana should be legalized and includes pictures related to drug addiction and marijuana use.
This document provides an overview of domestic violence. It defines domestic violence as abuse between intimate partners or family members that can be physical, sexual, emotional or economic. Statistics are given showing that millions of women are abused each year and over 1,500 domestic violence related deaths occur annually, mostly among women. Teen dating abuse is discussed as a precursor to domestic violence. Common types of abuse and myths about domestic violence are outlined. Signs of being in an abusive relationship and barriers to leaving are explored. Resources for victims seeking help are provided.
This document appears to be a resume or profile for Adrienne Grimes, a native of Washington D.C. who studied Media Communications at Full Sail University and Information Systems at University of Maryland Baltimore County. She has worked for the Department of Social Services and the Comptroller of the Currency. Her goal is to obtain an internship at a local broadcast station. She highlights communication, teamwork, and problem solving as strengths.
Alzheimer's is a progressive brain disease that destroys memory and thinking skills. It is the most common form of dementia among older adults. The main risk factors are increasing age and family history. Currently, there is no cure and treatment options can only temporarily slow the worsening of symptoms, which include memory loss, problems with thinking and reasoning, and emotional issues. Regular exercise is being studied as a potential way to prevent Alzheimer's. As the disease progresses, patients may require full-time care.
This document is a newsletter from SafeStrat providing safety information and resources. It announces safety materials for November, thanks readers, and provides links to presentations, books, articles and other resources. It includes a safety column on perseverance in achieving goals. Safety news, quotes and tweets are also presented.
Updated again based on my presentation on the 18th of March 2014 at the American Chamber of Commerce in Singapore. Previously presented at the Compliance Day Event for the Singapore Compliance Workgroup on 27-November 2013; and at the PrimeTime Personal Power Lunch and the CFO Asia Congress. We return to the same three economic questions: Who bribes? How much do they pay? And what value do they get? How can we use the answers to discourage bribery? And while we will never eliminate the motivation for bribery, we may reach the point where bribery is no longer business as usual.
I am sharing my slides under Creative Commons Attribution license. You are free to distribute, remix, tweak, and build upon my work, even commercially, as long as you credit me for the original creation by linking to this Slideshare URL. Each slide contains source attributions and URL; you should obtain the original images and data from the original sources before reusing. You must comply with any applicable license restrictions imposed by the original source.
This document discusses various forms of animal abuse including physical abuse, neglect, puppy mills, and dogfighting. It also explores the connection between domestic violence and animal abuse. Several organizations that work to address animal abuse are mentioned, including PETA, ASPCA, animal shelters, and the Humane Society. The line between love and abuse when training animals is examined as well.
NewsTrain instructor Jill Riepenhoff provided this handout of tips on developing data-driven enterprise stories off beats as part of the NewsTrain workshop in Columbus, Ohio, on Sept. 20, 2014. It include links to various databases of interest to reporters on beats such as health, sports, education, business, cops and courts, and government. Please see an associated PowerPoint presentation -- Data-Driven Enterprise on Any Beat. NewsTrain is a traveling workshop for journalists sponsored by Associated Press Media Editors. For more information, visit http://www.apme.com/?AboutNewsTrain
Globalization of Ethics and Compliance by @EricPesikEric Pesik
Globalization is not normally associated with ethics. But recent enforcement actions and legislation around the world point to a global ethics convergence. Where did it start? Where are we now? And what’s next for ethics and compliance?
I am sharing my slides from my lecture at the University of Buffalo School of Management Singapore Executive MBA program on September 21, 2013, under Creative Commons Attribution license. You are free to distribute, remix, tweak, and build upon my work, even commercially, as long as you credit me for the original creation by linking to this page URL. Each slide contains source attributions and URL; you should obtain the original images from the original sources before reusing. You must comply with any applicable license restrictions imposed by the original source.
This document lists various fruits - apples, bananas, blueberries, cherries, kiwis, mangoes, peaches, and strawberries. It also includes citations for web pages about the nutritional properties and growing information for each fruit.
Managing risk from top to bottom by @ericpesikEric Pesik
Managing Risk from the Top to Bottom: How to Safeguard Against Misconduct from C-Suite Level to Regular Employees – and Using HR as a Gatekeeper. Presented at American Conference Institute’s 3rd Asia Pacific Summit on Anti-Corruption, Compliance and Risk Management December 3, 2014, at the Hilton Singapore
Being Canadian involves valuing freedom as an individual, security, equality, community, pride, charity, acceptance, protection, and respect according to the document. The document lists these qualities and provides source images related to each one without further explanation.
This document discusses whether marijuana is harmful and explores potential solutions to drug use. It presents pictures related to drug addiction and rehabilitation as well as marijuana use to provide visual context. The document raises the serious issue of drug use and calls for efforts to stop it now through various solutions.
The document provides 5 source links to images and blog posts about taco trucks operating in inner cities and suburbs. The sources include photos of taco trucks and blog posts discussing taco trucks moving from urban areas to more residential neighborhoods for food.
The document provides tips for writing a resume from the Atlanta Workforce Development website. It recommends including your name, contact information, a summary of qualifications, work history including dates and descriptions of responsibilities and accomplishments, education, skills, and references on a resume to highlight your relevant experience and qualifications for potential employers.
Digital connections can help address issues related to communicable diseases, hospitals, and loneliness through remote image research on topics like infection, AIDS, and sneezing. URLs were provided for photos related to each search term to potentially aid further research efforts.
Homelessness affects many groups in society, including families, children, veterans, and young adults. There are approximately 1.7 million homeless young adults in the US. Everyone in society is impacted by homelessness in some way. People can help address this issue by donating to organizations that support the homeless or by volunteering their time.
Data Driven Enterprise off your Beat, a handout from the Producing Stories Effectively program at the Orlando NewsTrain May 15-16, 2015 by Ron Nixon. Ron Nixon is a Washington correspondent for The New York Times who covers the federal regulatory agencies. He is a visiting associate for journalism and media studies at the University of Witwatersrand in Johannesburg, South Africa, and a former adjunct professor at Howard University.
This document contains a list of 22 image URLs from various websites. The images include photos of vinyl records, guitars, microphones, maps, books, laptops, iPods, fireworks, Thanksgiving dinner, cheesecake, steaks, popcorn, water, oceans, rivers, televisions, movie posters, envelopes, Europe in the 1920s, famous paintings by Da Vinci and Van Gogh, Picasso's painting, houses, and small environmentally-oriented homes.
This is a drugs presentation for year 8 students who are learning about drugs and their effects of humans, this is being used as part of a PSHE course.
This document discusses drug abuse and addiction. It defines a drug as any substance used for medical purposes and defines addiction as habitual and uncontrolled dependence on a substance. It classifies types of drugs and their examples and discusses how drug addiction often begins due to factors like curiosity, peer pressure, depression, or a desire for excitement. The document specifically examines tobacco and nicotine, noting tobacco's origins and the stimulant and relaxing effects of nicotine but also its risks like increased heart disease and reduced fetal growth. It also looks at alcohol, explaining reasons for drinking like social pressures or wanting to escape difficulties in life. The overall goal is to raise awareness of the harmful effects of drugs.
The most common drug is marijuana. Marijuana use is increasing while opium and cocaine use are decreasing. The year 2000 saw the highest rates of drug use according to the document.
This document discusses the dangers of drug abuse, including addiction, health problems, and death. It notes that drugs can affect each person differently based on their brain chemistry and prior drug exposure. Common signs of drug abuse are listed, such as declining interest in activities, mood swings, and associating with known drug users. The most commonly abused drugs in the Philippines like methamphetamine, marijuana, and inhalants are described along with their short and long term negative health effects.
The document discusses drugs, drug abuse, and addiction. It defines drugs as substances that alter normal bodily functions when absorbed into the body. It notes that drug abuse is an intense desire to obtain increasing amounts of a substance and that drug dependence results in physical harm and behavioral issues over the long term. The document also shares the story of a teenager named Alby who abused drugs from ages 13 to 18 but was able to get treatment and now feels better about himself. It discusses surveys and activities conducted by students on these topics, including visiting a rehabilitation center.
This document discusses drugs and their effects. It defines a drug as any chemical that affects the body's functioning. It notes that heroin, alcohol, ecstasy, caffeine and nicotine are all forms of drugs. Drugs must pass through the body and into the brain to change brain cell functioning by interfering with neurotransmitters. Drugs can make people less aware and alert, and can relieve pain, but can also cause sleepiness, convulsions, comas and even death. Hard drugs are physically addictive and easy to overdose on, while soft drugs are not physically addictive. Illegal drugs are classified as Class A, B or C depending on their penalties for possession and dealing. The document provides signs that someone
Alzheimer's is a progressive brain disease that destroys memory and thinking skills. It is the most common form of dementia among older adults. The main risk factors are increasing age and family history. Currently, there is no cure and treatment options can only temporarily slow the worsening of symptoms, which include memory loss, problems with thinking and reasoning, and emotional issues. Regular exercise is being studied as a potential way to prevent Alzheimer's. As the disease progresses, patients may require full-time care.
This document is a newsletter from SafeStrat providing safety information and resources. It announces safety materials for November, thanks readers, and provides links to presentations, books, articles and other resources. It includes a safety column on perseverance in achieving goals. Safety news, quotes and tweets are also presented.
Updated again based on my presentation on the 18th of March 2014 at the American Chamber of Commerce in Singapore. Previously presented at the Compliance Day Event for the Singapore Compliance Workgroup on 27-November 2013; and at the PrimeTime Personal Power Lunch and the CFO Asia Congress. We return to the same three economic questions: Who bribes? How much do they pay? And what value do they get? How can we use the answers to discourage bribery? And while we will never eliminate the motivation for bribery, we may reach the point where bribery is no longer business as usual.
I am sharing my slides under Creative Commons Attribution license. You are free to distribute, remix, tweak, and build upon my work, even commercially, as long as you credit me for the original creation by linking to this Slideshare URL. Each slide contains source attributions and URL; you should obtain the original images and data from the original sources before reusing. You must comply with any applicable license restrictions imposed by the original source.
This document discusses various forms of animal abuse including physical abuse, neglect, puppy mills, and dogfighting. It also explores the connection between domestic violence and animal abuse. Several organizations that work to address animal abuse are mentioned, including PETA, ASPCA, animal shelters, and the Humane Society. The line between love and abuse when training animals is examined as well.
NewsTrain instructor Jill Riepenhoff provided this handout of tips on developing data-driven enterprise stories off beats as part of the NewsTrain workshop in Columbus, Ohio, on Sept. 20, 2014. It include links to various databases of interest to reporters on beats such as health, sports, education, business, cops and courts, and government. Please see an associated PowerPoint presentation -- Data-Driven Enterprise on Any Beat. NewsTrain is a traveling workshop for journalists sponsored by Associated Press Media Editors. For more information, visit http://www.apme.com/?AboutNewsTrain
Globalization of Ethics and Compliance by @EricPesikEric Pesik
Globalization is not normally associated with ethics. But recent enforcement actions and legislation around the world point to a global ethics convergence. Where did it start? Where are we now? And what’s next for ethics and compliance?
I am sharing my slides from my lecture at the University of Buffalo School of Management Singapore Executive MBA program on September 21, 2013, under Creative Commons Attribution license. You are free to distribute, remix, tweak, and build upon my work, even commercially, as long as you credit me for the original creation by linking to this page URL. Each slide contains source attributions and URL; you should obtain the original images from the original sources before reusing. You must comply with any applicable license restrictions imposed by the original source.
This document lists various fruits - apples, bananas, blueberries, cherries, kiwis, mangoes, peaches, and strawberries. It also includes citations for web pages about the nutritional properties and growing information for each fruit.
Managing risk from top to bottom by @ericpesikEric Pesik
Managing Risk from the Top to Bottom: How to Safeguard Against Misconduct from C-Suite Level to Regular Employees – and Using HR as a Gatekeeper. Presented at American Conference Institute’s 3rd Asia Pacific Summit on Anti-Corruption, Compliance and Risk Management December 3, 2014, at the Hilton Singapore
Being Canadian involves valuing freedom as an individual, security, equality, community, pride, charity, acceptance, protection, and respect according to the document. The document lists these qualities and provides source images related to each one without further explanation.
This document discusses whether marijuana is harmful and explores potential solutions to drug use. It presents pictures related to drug addiction and rehabilitation as well as marijuana use to provide visual context. The document raises the serious issue of drug use and calls for efforts to stop it now through various solutions.
The document provides 5 source links to images and blog posts about taco trucks operating in inner cities and suburbs. The sources include photos of taco trucks and blog posts discussing taco trucks moving from urban areas to more residential neighborhoods for food.
The document provides tips for writing a resume from the Atlanta Workforce Development website. It recommends including your name, contact information, a summary of qualifications, work history including dates and descriptions of responsibilities and accomplishments, education, skills, and references on a resume to highlight your relevant experience and qualifications for potential employers.
Digital connections can help address issues related to communicable diseases, hospitals, and loneliness through remote image research on topics like infection, AIDS, and sneezing. URLs were provided for photos related to each search term to potentially aid further research efforts.
Homelessness affects many groups in society, including families, children, veterans, and young adults. There are approximately 1.7 million homeless young adults in the US. Everyone in society is impacted by homelessness in some way. People can help address this issue by donating to organizations that support the homeless or by volunteering their time.
Data Driven Enterprise off your Beat, a handout from the Producing Stories Effectively program at the Orlando NewsTrain May 15-16, 2015 by Ron Nixon. Ron Nixon is a Washington correspondent for The New York Times who covers the federal regulatory agencies. He is a visiting associate for journalism and media studies at the University of Witwatersrand in Johannesburg, South Africa, and a former adjunct professor at Howard University.
This document contains a list of 22 image URLs from various websites. The images include photos of vinyl records, guitars, microphones, maps, books, laptops, iPods, fireworks, Thanksgiving dinner, cheesecake, steaks, popcorn, water, oceans, rivers, televisions, movie posters, envelopes, Europe in the 1920s, famous paintings by Da Vinci and Van Gogh, Picasso's painting, houses, and small environmentally-oriented homes.
This is a drugs presentation for year 8 students who are learning about drugs and their effects of humans, this is being used as part of a PSHE course.
This document discusses drug abuse and addiction. It defines a drug as any substance used for medical purposes and defines addiction as habitual and uncontrolled dependence on a substance. It classifies types of drugs and their examples and discusses how drug addiction often begins due to factors like curiosity, peer pressure, depression, or a desire for excitement. The document specifically examines tobacco and nicotine, noting tobacco's origins and the stimulant and relaxing effects of nicotine but also its risks like increased heart disease and reduced fetal growth. It also looks at alcohol, explaining reasons for drinking like social pressures or wanting to escape difficulties in life. The overall goal is to raise awareness of the harmful effects of drugs.
The most common drug is marijuana. Marijuana use is increasing while opium and cocaine use are decreasing. The year 2000 saw the highest rates of drug use according to the document.
This document discusses the dangers of drug abuse, including addiction, health problems, and death. It notes that drugs can affect each person differently based on their brain chemistry and prior drug exposure. Common signs of drug abuse are listed, such as declining interest in activities, mood swings, and associating with known drug users. The most commonly abused drugs in the Philippines like methamphetamine, marijuana, and inhalants are described along with their short and long term negative health effects.
The document discusses drugs, drug abuse, and addiction. It defines drugs as substances that alter normal bodily functions when absorbed into the body. It notes that drug abuse is an intense desire to obtain increasing amounts of a substance and that drug dependence results in physical harm and behavioral issues over the long term. The document also shares the story of a teenager named Alby who abused drugs from ages 13 to 18 but was able to get treatment and now feels better about himself. It discusses surveys and activities conducted by students on these topics, including visiting a rehabilitation center.
This document discusses drugs and their effects. It defines a drug as any chemical that affects the body's functioning. It notes that heroin, alcohol, ecstasy, caffeine and nicotine are all forms of drugs. Drugs must pass through the body and into the brain to change brain cell functioning by interfering with neurotransmitters. Drugs can make people less aware and alert, and can relieve pain, but can also cause sleepiness, convulsions, comas and even death. Hard drugs are physically addictive and easy to overdose on, while soft drugs are not physically addictive. Illegal drugs are classified as Class A, B or C depending on their penalties for possession and dealing. The document provides signs that someone
This document provides information about drugs and their effects. It defines drugs as substances that affect the body and brain, and notes that not all drugs are illegal. It then discusses different types of drugs like depressants, stimulants, and hallucinogens, providing examples of each and their effects. The document also addresses why people use drugs, signs of drug use, and what can be done to help someone with a drug problem.
This presentation discusses the history and effects of drug use and addiction. It begins by defining drugs and their medical uses. It then discusses how drug use has occurred among humans and animals for thousands of years. The presentation covers the causes and negative effects of drug abuse and addiction, including health issues, social problems, and criminal behavior. It also provides details on the production of major drugs like opium and organizations working to address addiction worldwide and in Pakistan.
- Drug addiction and abuse refers to the chronic or habitual use of any chemical substance to alter states of body or mind for non-medical purposes. This includes both licit and illicit drugs.
- Addiction is compulsive drug use despite harm, while substance abuse refers to frequently using drugs like alcohol and inhalants that can be addictive.
- Dependence involves psychological need for a drug and physical tolerance and withdrawal symptoms. Addiction affects the reward pathway in the brain.
- Drug abuse has negative effects on individuals, families, and society through health issues, crime, and lost productivity.
The document discusses drug addiction and its effects. It addresses different types of drugs like alcohol, heroin, cocaine, meth, and marijuana. It explains how drugs affect the brain and describes signs of addiction. The document also discusses rehabilitation options and concludes that it is important for people to say no to drugs to avoid a potentially lifelong struggle with addiction.
The document discusses drug addiction and its effects. It addresses how addiction affects the brain and body, examines different types of drugs like cocaine and heroin, and explores rehabilitation options. Signs of alcoholism are provided. The conclusion emphasizes that it is better to avoid drugs and say no to prevent addiction.
The document discusses various drugs including alcohol, marijuana, cocaine, heroin, methamphetamine, and crack. It provides images showing the physical effects of drug addiction on the brain and body for different substances. The text also covers definitions of drug addiction, the causes of addiction, and symptoms of alcoholism.
I did this presentation when I was a senior in high school. Hazing, substance abuse, bullying in other forms, and other social issues such as loneliness and mental health have always caught my attention and are my passions. I want to be a counselor and these issues are important to address. Especially when it comes to making the future bright these presentations are suppose to be eye opening and not to change an individual's view on the issue or their political idealogies but to challenge their hearts and souls to stop such tragedies from happening or again or just make them think of the complex layers of this and other issues.
White Nose Syndrome is a disease affecting bat populations. It causes large mortality rates in hibernating bat colonies and has spread rapidly since first being documented in 2006. More research is still needed to develop a cure, but funding is helping to support studies. Potential solutions discussed include a vaccination that could be spread to bats in mist form, but this would require further study before being implemented. Overall the document discusses the threat of White Nose Syndrome to bat populations and the ongoing scientific efforts to address it.
White Nose Syndrome is a disease affecting bat populations. It is caused by a cold-loving fungus that thrives in cold caves and mines where bats hibernate in winter. The disease has killed over 1 million bats and continues to spread. More research is needed to develop a cure, but a possible solution may be a vaccination administered as a mist to help control the disease at a large scale. Increased government funding would support further research toward controlling White Nose Syndrome.
White Nose Syndrome is a disease affecting bat populations. It causes large mortality rates in bats and threatens their survival. More research is still needed to develop a cure. The document discusses the need for increased government funding to study the disease and potential solutions like a vaccination administered through mist to large numbers of bats. However, a cure will require more research.
White Nose Syndrome is a disease affecting bat populations. It is caused by a cold-loving fungus that thrives in cold caves and mines where bats hibernate in winter. The disease has killed over 1 million bats and continues to spread. More research is needed to develop a cure, but a possible solution may be a vaccination administered as a mist to help control the disease at a large scale. Increased government funding would support further research efforts.
White Nose Syndrome is a disease affecting bat populations. It is caused by a cold-loving fungus that thrives in caves and mines where bats hibernate in winter. The disease has killed over 1 million bats and continues to spread rapidly. More research is needed to develop a cure, but possibilities include a vaccination that could be spread in a mist to protect large numbers of bats. Increased government funding would support further studies aimed at controlling this disease.
The document discusses how some companies exploit breast cancer awareness for profit by deceptively marketing pink ribbon products without actually contributing much of the proceeds to breast cancer research. It notes that some products labeled as supporting breast cancer causes are not clearly disclosed as to what portion of funds are actually donated, and consumers should carefully check labels and research companies to understand how their purchases might meaningfully help breast cancer efforts.
This Powerpoint shows about Child Malnutrition in Ethiopia that includes introduction, cause & effect and conclusion. For instance, some children get malnutrition which can lead to many diseases. And finally how to slove this problem.
World Environment Day 2012's theme was "Green Economy: Does it Include You?". The document contrasts a polluted future without a green economy with a more sustainable green future with fresh air, clean water, recycled waste and healthy ecosystems. It emphasizes that individuals and communities must promote green economies through improved sources of income, resources, education and more to ensure future generations inherit a greener world.
The document discusses concerns about radioactive contamination of baby formula in Japan following the Fukushima nuclear disaster. Images show the damaged Fukushima nuclear plant, maps of radiation levels around the plant, and stock photos related to food and nutrition. The main article is from a Canadian news source and focuses on the Japanese government restricting sales of baby formula from two prefectures near Fukushima over radiation concerns.
The document poses a series of sociological questions about how various modern influences have impacted society and culture over time. Some of the topics addressed include the impact of TV dinners and microwaves on family traditions and health, the relationship between media/games and violence/bullying in youth, changing views of homosexuality and gender roles, the rise of artificial beauty standards promoted by celebrities, the medicalization of health, debates around birth control and abortion, changing views of marriage, immigration issues, and the impact of television on family bonding and the distinction between information and entertainment.
1. The document provides instructions on how to make a zombie using various drugs and toxins.
2. Key ingredients include atropine and scopolamine extracts which can cause delirium and altered mental states when ingested.
3. Tetrodotoxin from pufferfish and batrachotoxin from frogs and toads can also induce paralysis and an appearance of death but leave cognitive functions intact.
Being Canadian involves valuing freedom as an individual, security, equality, community, pride, charity, acceptance, protection, and respect according to the document. The document lists these qualities and provides source images related to each value.
Being Canadian involves valuing freedom as an individual, security, equality, community, pride, charity, acceptance, protection, and respect according to the document. The document lists these qualities and provides source images related to each value.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
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1. Drug Addiction Allison Touchstone http://www.flickr.com/photos/latin_snake/2608354549/lightbox/
2. Thesis Statement Drug addiction is a devastating issue that is affecting our society today. Addiction takes on many forms. Whether it is alcoholism, or substance abuse. It affects both the abuser, their family and friends emotionally, mentally, financially and physically http://www.salvationarmysouth.org/spiritualformation/images/drugs.jpg
19. “Physicians who are familiar with alcoholism agree there is no such thing as making a normal drinker out of an alcoholic.” -ALCOHOLICS ANONYMOUS, The Big Book http://www.amillionlives.com/wp-content/uploads/2011/03/Effects-of-Alcoholism.jpg http://www.notable-quotes.com/a/alcoholism_quotes.html
20. Signs of Alcoholism Drinking for relief Need for increasingly large amounts of alcohol to feel drunk “Blackouts” : Not being able to remember events or block of time while drinking Not admitting to having a problem Hiding drinking from others Sneaking drinks Increasing thoughts about alcohol Planning events or entire days around drinking Drinking as soon as they wake up Personality changes and mood swings http://www.nytimes.com/2007/06/27/dining/27drin.html?_r=1
24. The Dangers of Meth http://www.cityofdouglaswy.com/vertical/Sites/%7B52347BB1-2476-45A1-A80E-FDF4BD158A35%7D/uploads/%7BCB8221C6-27BE-4B2D-AE32-F84CCFD582EA%7D.JPG
33. Class Activity http://www.mdottrafficsafety.com/Programs/safetyEductationPrograms/Pages/Fatal-Vision-Goggles.aspx
34. Works Cited Shaw, Brian F., Paul Ritvo, and Jane Irvine. Addiction & Recovery for Dummies. Hoboken, NJ: Wiley, 2005. Print Gwinnell, Esther, and Christine A. Adamec. "Heroin." The Encyclopedia of Drug Abuse. New York NY: Facts On File, 2008. Print Karr, Justin. Alcoholism. Detroit: Greenhaven, 2008. Print. Walker, Ida. Addiction in America: Society, Psychology, and Heredity. Philadelphia: Mason Crest, 2008. Print. Etingoff, Kim. Methamphetamine: Unsafe Speed. Philadelphia: Mason Crest, 2008. Print. Goodwin, William. Marijuana. San Diego, CA: Lucent, 2002. Print. Barter, James. Cocaine and Crack. San Diego, CA: Lucent, 2002. Print. Lennard-Brown, Sarah. Marijuana Chicago, Illinois: Raintree, 2005. Print.
35. Conclusion In conclusion drug addiction is a problem that needs to be taken seriously.It is so much easier to say no then it is to go through rehab and to quit, because once you’re addicted it can take a lifetime of pain to become clean again. So save your life and say no. http://farm3.static.flickr.com/2653/3916151288_6daaf5741d_z.jpg?zz=1
Editor's Notes
My uncle, who has been an addict for 37 years has been to rehab multiple times, none of which have been successful. Began using marijuana when he was 14 years old and it has since escalated from there. Has used Crack, Cocaine, LSD, Meth, Ecstasy, Prescription Drugs such as Xanex and Oxycotin, Methaqualone (a pill that’s side effects include, euphoria, drowsiness, reduced heart rate, reduced respiration, increased sexual arousal, paresthesias, which is the numbness of the fingers and toes, respiratory depression, slurred speech, headache and sensitivity to light. Essentially an alcoholic blackout in a pill) and Heroin. Currently still addicted to Heroin and Cocaine. So this inspired me to do this project on drugs and alcohol because I have seen what it can do to a family, I have personally seen how it can emotionally mentally and financially hurt an addicts loved ones, because I have seen my family hurt due to my uncles addiction.
A chemical substance that affects the process of the mind or body. A substance other than food intended to affect the structure or function of the body. Anything that can be inhaled, injected or ingested. It is important to remember that drugs will effect everyone differently. What may not have any effect on you could have a drastically different effect on someone else. Example Vicodin: wisdom teeth , people who I have talked to have said the vicdoin has made them extremely nauseous but with me I had no nausea at all.
Stimulants A substance that temporarily produces an increase of the the body’s activity, Cocaine, Meth. Depressants Substance that temporarily decreases the function or activity of the body, Alcohol, Marijuana. Hallucinogens Chemicals that alter perception, thought and mood. name describes that the drug will include hallucinations, LSD.
persistent and compulsive dependence on a behavior or substance. Addiction tears families apart and causes pain and suffering for the loved ones of the addict.Addiction affects not only the abuser, but the abusers family, friends, and loved ones in many different way; emotionally, physically, financially and mentally. What determines an addiction: You build up tolerance, meaning it takes more of the drug of choice to feel that high. And withdraw symptoms meaning when you stop using the drug of choice for an extended period of time your body doesn’t know how to handle it. Some withdraw symptoms include but are not limited to, vomiting, sweating, anxiety, increased heart rate, tremors (which is uncontrollable shaking of the body). Withdraw symptoms can be as severe as, heart attack stroke and seizures Determining an addiction Building up a tolerance Withdraw symptoms
EXPOSURE FROM PEERSThe more you’re around an addictive substance, especially around peers, the more likely you are to use it2. PARENT USAGE A child seeing a parent use a drug usually makes the child feel as though it’s okay. Children also want to be like their parents3. AVAILABILITY The more available certain substance are, the more likely to want to try and more likely to get ahold of 4. GENETICS If a relative has been an addict it affects the genetic disposition weaking someone’s ability to resist abuse5. POOR HOME LIFE Most addicts have been reported to not have had a good relationship with their immediate family when they were younger 6. Psychological issuesIndividuals who have a psychological issue are more prone to having a drug problem rather then healthy ones7. PersonalityIndividuals who have anger issues, or are shy will may have a higher chance of becoming addicted
The normal brain
Notice the holes in the heroin addicts brain. They all represent dead activity, or areas of the brain that no longer work.
Once again notice the spaces in the addicts brain they represent areas that no longer function
Crack become popular in the late 1980s and early 1990s. Hospitals began getting hundreds of patients dying or getting severely ill due to crack addictions. Social services was also being hit hard with hundreds of abandon children due to their parents crack addiction. Local police and federal drug enforcement officers began overfilling local jails with users and dealers. Crack eventually began becoming popular within gangs who realized they could make more money by selling crack. Around this time is when crack houses began popping up all over the East Coast slums while dealers and users started to find ways to use and deal out of site of rivalry gangs and law enforcement. While these crack houses did provide users and dealers the protection they were after they were often extremely run down, with no running water, electricity, or trash collection. Which lead to being a disease ridden building that most people were unable to live in and ended back up on the streets back to their old habits with crack.
In the early 20th century cocaine was thought to be a safe energy booster and pain reliever. Until individuals kept taking the pain reliever more and more often. Short term and long term psychological side effects Short: rapid heart rate (leads to increased amount of blood pumping through the body) increased blood pressure, and increased body temperature, also chemically alters the brain to produce a large about of dopamine Long: Blood vessels in the brain become more narrow which as a result doesn’t provide the brain enough oxygen. When deprived of oxygen brain cells begin to die. An abusers brain eventually shrinks, becomes discolored and poorly functioning. The heart beats four times faster than normal leadign to a condition called tachycardia and what that is, is the heart beats 100 times or more per minute causing severe chest discomfort, which will eventually lead to death. These all permanentCocaine become widely popular in the 1970s where users saw the drug as a “harmless recreational drug”, and was used by many celebrities such as Kurt Kobain and David Bowie, which then individuals saw it to be okay to use.
About 17.6 million Americans are Alcoholics. Causes: Genetics: Studies have shown a genetic predisposition to alcoholism: this being, the Amygalda, which is the area of the brain that is believed to play a large roll in cravings, is significantly smaller in individuals with a family history of alcohol addiction. Certain individuals have abnormal levels of serotonin which is a neurotransmitter. Abnormal levels of serotonin results in abnormally high tolerance levels for alcohol. The user with the abnormal level is obviously more likely to be able to drink a lot more. Biology: Scientist and researches have been looking at how long term alcohol usage seems to deplete the brain’s supply of dopamine and serotonin. This is showing that long term addiction is actually changing the brains chemistry and the alcohol has no physical effect on the drinker, he or she only believesit doesCulture: People are going to be willing to drink more when they see people they look up to in the media drinking. Most commercials are focused towards a younger demographic, not only that but college life is often built around time you spend drinking.Age: The longer you drink the more likely you are to develop an alcohol problem. Adolescents are at a higher risk of developing an alcohol problem, due to history of abuse, family violence, and depression. Craving of other substaces :--Alcohol Addiction: Not Worth the Buzz
What this quote is saying that once you abuse alcohol you can no longer be a social drinker. After becoming an alcoholic, drinking becomes something you can no longer control. Alcoholics do not know how to only have one drink.
About 144 million people over the age fifteen have admitted to smoking marijuana, which is the largest group of illegal drug usage It is important to know that cannabis and marijuana are two very different things. Cannabis has been used for thousands of years for many different things, paper, cloth and rope. While marijuana is made from the dried leaves and the buds of the plant. Users often report that the drug makes them feel happy, relaxed haand stimulated, it automatically effects the users brain and nervous system. A lot of people are under the impression that smoking marijuana is not harmful but that’s not the case at all there are numerous long term and short term effects. Some short term effects include inhibition of the ability to learn, inhibition of memory, impaired judgment where long term effects include the functioning of immune system is drastically affected, lung disease, long term usage can result in a low sperm count for men and irregular periods for women. And these are just a few there is still a very long list of effects
Marijuana effects the body in many different ways, it effects the brain, the lungs, the heart and the users mental health. It effects the brain in that it is similar to alcohol in the way it effects the users ability to control movement, impairing judgment, and making it dangerous to drive a car. Some scientists feel that marijuana changes the way that the brain cells connect with each other and studies have shown that year of usage have resulted in to have difficulties with memory and problem solving. Marijuana effects the heart in that it increases the users heart rate, to about the speed of that of strenuous exercise. Lungs: marijuana effects the lungs by causing lung damage, damage that is worse then that of someone who smokes cigarettes. This is for several reasons, hand rolled marijuana cigarettes do not have a filter where as manufactured ones do. The filter is used to decrease the amount of chemicals inhaled. Also because marijuana smokers take bigger breaths then cigarette smokers meaning smoke flows deeper into their lungs and they hold it there longer, therefore increasing the risk for damage and disease. Cigarette smoke and marijuana smoke have similar chemicals that damage the the lung throat and mouth. Therefore marijuana is just as dangerous as cigarette smoking if not worse.
Meth is a mad made drug which includes but not limited too, battery acid, paint thinner, brake cleaner, drain cleaner, acetone, cold medicine, iodine crystals, ammonia and Freon (which is used in refrigerators). Meth is a stimulant that speeds up the brains activity, increases energy, alertness, breathing rate, blood pressure and decreases the need for sleep. Meth can be smoked, injected, inhaled or taken in a pill form. Street names for meth are, speed, chalk, glass, yaba and ice when in the form that it is able to smoked. Meth has not always been viewed as a dangerous drug in the 1930s it was originally used for the treatment of asthma. During the Great Depression people used meth to help deal with stress. As people began to realize it increased awareness and you required less sleep while using meth it started to become available to the soldiers in World War II, the Vietnam War and Desert Storm. Soon after war usage meth quickly became popular throughout the public. Users would combine it with the weight loss medication amphetamine 1960 . Which is where the name Methamphetamine comes from. Meth works by altering the individuals behavior because it directly targets the neurotransmitters which are chemicals that send signals between neuron. Meth directly conflicts with the making of dopamine, it creates much more then the normal amount which causing feelings of extreme happiness
Long term effects: irreversible brain damage that can cause memory loss, trouble with movement, learning impediments and ultimately death. Vascular problems including increased heart rate and heart failure. And even stroke. Not only vascular problems but kidney lung and liver damage again all of which will lead to death Less severe long term effects are acne, teeth grinding, slurred speech, dilated pupils, dry skin, and excessive sweating Short term effects: headaches blurred vision dizziness, dry mouth, severe insomnia, and athetosis, which is repetitive slow involuntary movements which is especially severe in the hands.When taking a large dose in a short amount of time it can have much more severe effects such as dangerously high body temperatures, which ultimately results in hypothermia which will then cause convulsions that can lead to deathMeth doesn’t only effect the body psychically, the user will experience extreme behavior changes, with extreme confidence and high levels of energy and alertness. When the high wears off the user will experience severe aggression, nervousness, irritability, confusion and depression. Not only changes in mood but users will also pick at the face and hands do to the fact that they feel as though they have bugs crawling in their skin causing open sores and scarring. Scarring is not only from picking at the skin but searching for available veins. As many veins collapse due to extended usage. This leads to not only a physical addition but a psychological addiction as well. Meth users are often found to develop symptoms of schizophrenia and these symptoms can become so bad that the user that they can cause the user to have thoughts of murder or suicide
Highly addictive drug that is processed from morphine, which in itself if derived from opium poppies (opium being a flower). Heroin has a higher potency then morphine does due to chemical reactions. Afghanistan is actually the worlds largest producer of heroin, even though most addicts in the united states use heroin that comes from mexico and south america. Heroin is usually white or brown in color but it can be sold in a sticky black substance which is known as black tar heroin and what that is is heroin mixed with milk, starch, sugar quinine (medication to treat malaria) and is laced with strychnine (which is a pesticide used for killing rats). According to the United Nations Office of Drugs and Crime, about 9.2 million people are addicted to heroin world wide. When first using heroin you sense a “rush” and extreme euphoria. However after addicted use is continued to reduce withdraw symptoms. Once the drug is in the blood stream the user will feel drowsy and mental functioning is impaired which is sometimes referred to as nodding. Some other symptoms include, decreased heart rate, slow breathing which can become so slow that the user will die, vomiting which would occur in newer users. A study done by the National Institute on Drug Abuse has shown that some addicts go through the rehabilitation only to feel the initial euphoria. Heroin can be injected, snorted or smoked. Short term effects : nausea and vomiting, miscarriage, slow mental functioningLong term: contraction of diseases such as HIV through the sharing of needles, infections of the lining of the heart and heart valves, arthritis, collapsed veins, liver and kidney disease, and lung infections such as pneumonia and tuberculosis
The 12 step programsSelf Help ProgramsAlternative Treatments
Over 2 million people in the world participate in 12 step programs such as Alcoholics Anonymous. The main idea of 12 step programs is to admit you have a problem. Which is why at the beginning of each meeting users have to stand up, state there name and say I am an alcoholic or I am addicted to heroin, etc. The 12 steps is also very religious, they’re all about working with God to help overcome your addiction. The actual 12 steps areWe admitted we were powerless over alcohol or our drug use. That out lives have become unmanageable Came to believe that a Power greater then ourselves could restore our sanity Made a decision to turn out wil and out lives over to the care of God as we understood him Made a searching and fearless moral inventory of ourselves Admitted to God, to ourselves and to another human being the exact nature of our wrongsWere entirely ready to have God remove all these defects of character Humbly ask Him to remove our shortcomingsMade a list of persons we had harmed and became willing to make amends to them allMade directs amends to such people wherever possible except when to do so would injure them or othersContinued to take personal inventory and when we were wrong promptly admitted it.Sought through prayer and meditation to improve out conscious contact with God as we understood Him praying for only knowledge of His will for us and the power to carry that outHaving had a spiritual awakening as the result of these steps we tried to carry this message to alcoholics and to practice these principles in all out affairs
Self help groups usually have moderators who have recovered from addiction themselves leading the group. They help involve you in peer support and counseling. Most people find self help groups more helpful rather then the 12 steps programs because they’re led by someone who has actually been through what they’re going through. And has experienced the highs and lows of recovery. The follow the rules ofAbstinence: there is no reason at all to drink or to use againDetermination: never look back, especially when things get tough. You have another chance in life and not many get that chance. Your sobriety doesn’t fix everything but its definitely a start and it makes everything possibleHonesty: Get everything out in the open. Get ride of the shadows and the darkness of the past. Shine light on the shadows and they lose they’re power. Even problems that can be dealt with reasonably when they’re truthfully reviewedPeople: Human interaction is extremely powerful. If you meet people who are also in recovery. Your interactions with them can fight old patters. To fi
Acupuncture people believe that with acupuncture treatments it will stimulate the flow of chee which is the flow of energy thus removing the “bad energy” of drug useIbogaine plant based remedy that is believed to have anti addictive characteristics. It chemistry ibogaine is considered an alkaloid which relieves dependency and withdraw symptoms making it easier to stop using
All in all this project has taught me a lot. It has helped me somewhat understand what my uncle is going through with his addiction and has given me some sense of closure.