Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...Paul Molloy
Background. Prevention strategies have long been
sought to reduce the incidence and burden of postoperative
atrial fibrillation (POAF) after heart surgery.
However, none has emerged as a dominant and widely
applicable prophylactic measure. The purpose of this
review is to consider the biological mechanisms by which
shed mediastinal blood leads to oxidation and inflammation
within the postoperative pericardial environment
and how this might trigger POAF in susceptible persons,
.....
Pericardial Blood as a Trigger for POAF Affter Cardiac Surgery ~ Annals of Th...Paul Molloy
Background. Prevention strategies have long been
sought to reduce the incidence and burden of postoperative
atrial fibrillation (POAF) after heart surgery.
However, none has emerged as a dominant and widely
applicable prophylactic measure. The purpose of this
review is to consider the biological mechanisms by which
shed mediastinal blood leads to oxidation and inflammation
within the postoperative pericardial environment
and how this might trigger POAF in susceptible persons,
.....
OPEN ACCESS: Prognostic implications of conversion from non-shockable to shoc...Emergency Live
The prognostic significance of conversion from non-shockable to shockable rhythms in patients with initial non-shockable rhythms who experience out-of-hospital cardiac arrest (OHCA) remains unclear. We hypothesized that the neurological outcomes in those patients would improve with subsequent shock delivery following conversion to shockable rhythms, and that the time from initiation of cardiopulmonary resuscitation by emergency medical services personnel to the first defibrillation (shock delivery time) would influence those outcomes. READ MORE HERE: http://ccforum.com/content/18/5/528/abstract#
To study the variations of autonomic nervous system in hypertensive patients using a set of autonomic function tests
and to correlate cardiac autonomic function with Heart rate variability in hypertensives. Background: The pathophysiological mechanism for the development of hypertension is the lack of balance between sympathetic and parasympathetic nervous system. Both Heart rate variability (HRV) and Autonomic function tests provide a tool to know the concept of autonomic modulation of heart. They also forms an index of cardiac autonomic regulation. Methods: The study included 50 hypertensive patients and 50 normotensive
subjects. All the subjects underwent for the analysis of heart rate variability in time domain (TD) and frequency domain and a set of autonomic function tests were done to assess the autonomic functions. These results were compared with age and sex matched controls (normotensives). The subjects were selected based on exclusion-inclusion criteria. Results: Results showed that S: L ratio, Valsalva ratio & Heart rate response to deep breathing test values were decreased in Hypertensives as compared to Normotensives (p<0.05).><0.05). Both the time domain and frequency domain values of HRV reduced significantly in hypertensives indicated that there is increased sympathetic activity and decreased parasympathetic activity. Conclusion: From this study, it is evident that Hypertension can alter the normal autonomic functions of the body and predisposes to autonomic neuropathy. Early and regular screening of these individuals is necessary to prevent any future complications.
Cardiology
From Wikipedia, the free encyclopedia
Jump to navigationJump to search
This article is about the medical specialty. For the album, see Cardiology (album). For the medical journal, see Cardiology (journal).
Cardiology
Heart diagram blood flow en.svg
Blood flow diagram of the human heart. Blue components indicate de-oxygenated blood pathways and red components indicate oxygenated blood pathways.
System Cardiovascular
Subdivisions Interventional, Nuclear
Significant diseases Heart disease, Cardiovascular disease, Atherosclerosis,
earning websites that make the most money
Quantifying Cardiovascular and Behavioral Correlates of Fear in Mice: Implica...InsideScientific
To learn more and watch the webinar, go to:
https://insidescientific.com/webinar/quantifying-cardiovascular-and-behavioral-correlates-of-fear-in-mice-implications-for-ptsd-and-cardiovascular-disease-risk/
Post-traumatic stress disorder (PTSD) is a prevalent neuropsychological disorder that is in part characterized by exaggerated cardiovascular and autonomic arousal to trauma reminders, which over time may contribute to greater risk for cardiovascular disease (CVD) development (ie., stroke, hypertension). In both humans and rodents, cardiovascular and autonomic responses are strong measures of fear or threat assessment and therefore understanding how these systems go awry in anxiety disorders such as PTSD is critical for improving current PTSD therapies as well as reducing CVD risk in this population.
In this webinar, Dr. Paul Marvar and Benjamin Turley discuss research related to innovative methodology developed in rodent models for pairing real-time multi-modal assessment of behavioral (ie., freezing, startle) and cardiovascular (ie., blood pressure, heart rate) responses to cued fear learning and how these approaches may better inform underlying cardiovascular and autonomic impairments in fear-based disorders, such as PTSD.
Key Topics Include:
- To understand the physiological impact of PTSD on cardiovascular and autonomic homeostasis, CVD risk
- To understand how rodent models of conditioned fear learning can be used to assess real-time cardiovascular and autonomic fear or defensive emotional states in both home-cage and novel environments
- To further understand the benefits for using integrated behavioral and cardiovascular multi-modal methodologies and its translational implications for improved treatments for PTSD and CVD comorbidity
In this American Physiological Society (APS) webinar produced in partnership with ADInstruments, DeWayne Townsend, DVM, PhD and Adam Goodwill, PhD discuss how to collect and analyze quality pressure-volume loop data.
Specifically, they discuss why PV loops are considered the gold standard for measuring cardiac function in vivo, what equipment is required to collect PV loop data, and how to minimize variability in your data. The focus of the webinar is on data analysis – DeWayne and Adam demonstrate how to analyze load-independent measures of function and discuss what the data mean.
Key Learning Objectives Include:
– Why PV loops? What are the alternatives (e.g. echo, MRI, etc.) and how do PV loops compare?
– Why is the Starling effect important?
– Load independent measures: what are they and how are they measured? How are data analyzed and what do they mean?
– Equipment basics: what do you need to record PV loop data?
– What causes variability and how do you mitigate it?
An Integrated Understanding of Pressure and Flow – An Essential PartnershipInsideScientific
A tightly controlled relationship between blood pressure and organ blood flow is vital for matching an organ’s metabolic needs to the delivery of oxygen and nutrients. However, the nature of the pressure-flow relationship is complex and governed by multiple control systems, including local autoregulatory mechanisms at the level of the individual organ, as well as neural and hormonal modulation. To fully understand how pressure-flow relationships operate in health, and may be altered in pathological settings, it is essential to make direct, long-term assessments of blood pressure and blood flow under normal physiological conditions (ie in the conscious state).
In this presentation, Dr. McBryde shares insights from her studies of how the relationship between blood pressure and blood flow is altered in hypertension, to “consumer” organs such as the brain, and to “supply” circulations such as the mesenteric venous pool. She also discusses the variables that go into gathering accurate measurements of these two parameters in a lab setting.
Exploring Applied Physiology of the Cardiovascular System
The cardiovascular system is a cornerstone of human health, regulating the circulation of vital nutrients, oxygen, and waste products throughout the body.
Understanding the applied physiology of this system is essential for healthcare professionals to provide effective medical care and interventions.
Importance of Applied Cardiovascular Physiology
Effective healthcare requires a deep comprehension of how the cardiovascular system functions under various conditions.
Applied physiology knowledge empowers healthcare practitioners to make informed decisions, diagnose disorders, and formulate targeted treatment plans.
Focus on Practical Applications in Healthcare
This presentation delves into the practical aspects of cardiovascular physiology that directly impact clinical practice.
We will explore how physiological concepts are translated into real-world medical scenarios and interventions.
By grasping the applied physiology of the cardiovascular system, healthcare providers can optimize patient care, enhance diagnostics, and improve treatment outcomes.
Throughout this presentation, we'll bridge the gap between theoretical understanding and its practical implications in the field of healthcare.
Understanding the Components
The cardiovascular system comprises three crucial components: the heart, blood vessels, and blood.
Heart: A muscular organ that pumps blood, ensuring a continuous flow throughout the body.
Blood Vessels: A network of tubes that transport blood to and from various tissues.
Blood: A specialized fluid that carries nutrients, oxygen, hormones, and removes waste products.
Role in Oxygen and Nutrient Delivery
Oxygen from the lungs and nutrients from the digestive system are transported to body tissues through the bloodstream.
These essential components are required for cellular metabolism and energy production.
OPEN ACCESS: Prognostic implications of conversion from non-shockable to shoc...Emergency Live
The prognostic significance of conversion from non-shockable to shockable rhythms in patients with initial non-shockable rhythms who experience out-of-hospital cardiac arrest (OHCA) remains unclear. We hypothesized that the neurological outcomes in those patients would improve with subsequent shock delivery following conversion to shockable rhythms, and that the time from initiation of cardiopulmonary resuscitation by emergency medical services personnel to the first defibrillation (shock delivery time) would influence those outcomes. READ MORE HERE: http://ccforum.com/content/18/5/528/abstract#
To study the variations of autonomic nervous system in hypertensive patients using a set of autonomic function tests
and to correlate cardiac autonomic function with Heart rate variability in hypertensives. Background: The pathophysiological mechanism for the development of hypertension is the lack of balance between sympathetic and parasympathetic nervous system. Both Heart rate variability (HRV) and Autonomic function tests provide a tool to know the concept of autonomic modulation of heart. They also forms an index of cardiac autonomic regulation. Methods: The study included 50 hypertensive patients and 50 normotensive
subjects. All the subjects underwent for the analysis of heart rate variability in time domain (TD) and frequency domain and a set of autonomic function tests were done to assess the autonomic functions. These results were compared with age and sex matched controls (normotensives). The subjects were selected based on exclusion-inclusion criteria. Results: Results showed that S: L ratio, Valsalva ratio & Heart rate response to deep breathing test values were decreased in Hypertensives as compared to Normotensives (p<0.05).><0.05). Both the time domain and frequency domain values of HRV reduced significantly in hypertensives indicated that there is increased sympathetic activity and decreased parasympathetic activity. Conclusion: From this study, it is evident that Hypertension can alter the normal autonomic functions of the body and predisposes to autonomic neuropathy. Early and regular screening of these individuals is necessary to prevent any future complications.
Cardiology
From Wikipedia, the free encyclopedia
Jump to navigationJump to search
This article is about the medical specialty. For the album, see Cardiology (album). For the medical journal, see Cardiology (journal).
Cardiology
Heart diagram blood flow en.svg
Blood flow diagram of the human heart. Blue components indicate de-oxygenated blood pathways and red components indicate oxygenated blood pathways.
System Cardiovascular
Subdivisions Interventional, Nuclear
Significant diseases Heart disease, Cardiovascular disease, Atherosclerosis,
earning websites that make the most money
Quantifying Cardiovascular and Behavioral Correlates of Fear in Mice: Implica...InsideScientific
To learn more and watch the webinar, go to:
https://insidescientific.com/webinar/quantifying-cardiovascular-and-behavioral-correlates-of-fear-in-mice-implications-for-ptsd-and-cardiovascular-disease-risk/
Post-traumatic stress disorder (PTSD) is a prevalent neuropsychological disorder that is in part characterized by exaggerated cardiovascular and autonomic arousal to trauma reminders, which over time may contribute to greater risk for cardiovascular disease (CVD) development (ie., stroke, hypertension). In both humans and rodents, cardiovascular and autonomic responses are strong measures of fear or threat assessment and therefore understanding how these systems go awry in anxiety disorders such as PTSD is critical for improving current PTSD therapies as well as reducing CVD risk in this population.
In this webinar, Dr. Paul Marvar and Benjamin Turley discuss research related to innovative methodology developed in rodent models for pairing real-time multi-modal assessment of behavioral (ie., freezing, startle) and cardiovascular (ie., blood pressure, heart rate) responses to cued fear learning and how these approaches may better inform underlying cardiovascular and autonomic impairments in fear-based disorders, such as PTSD.
Key Topics Include:
- To understand the physiological impact of PTSD on cardiovascular and autonomic homeostasis, CVD risk
- To understand how rodent models of conditioned fear learning can be used to assess real-time cardiovascular and autonomic fear or defensive emotional states in both home-cage and novel environments
- To further understand the benefits for using integrated behavioral and cardiovascular multi-modal methodologies and its translational implications for improved treatments for PTSD and CVD comorbidity
In this American Physiological Society (APS) webinar produced in partnership with ADInstruments, DeWayne Townsend, DVM, PhD and Adam Goodwill, PhD discuss how to collect and analyze quality pressure-volume loop data.
Specifically, they discuss why PV loops are considered the gold standard for measuring cardiac function in vivo, what equipment is required to collect PV loop data, and how to minimize variability in your data. The focus of the webinar is on data analysis – DeWayne and Adam demonstrate how to analyze load-independent measures of function and discuss what the data mean.
Key Learning Objectives Include:
– Why PV loops? What are the alternatives (e.g. echo, MRI, etc.) and how do PV loops compare?
– Why is the Starling effect important?
– Load independent measures: what are they and how are they measured? How are data analyzed and what do they mean?
– Equipment basics: what do you need to record PV loop data?
– What causes variability and how do you mitigate it?
An Integrated Understanding of Pressure and Flow – An Essential PartnershipInsideScientific
A tightly controlled relationship between blood pressure and organ blood flow is vital for matching an organ’s metabolic needs to the delivery of oxygen and nutrients. However, the nature of the pressure-flow relationship is complex and governed by multiple control systems, including local autoregulatory mechanisms at the level of the individual organ, as well as neural and hormonal modulation. To fully understand how pressure-flow relationships operate in health, and may be altered in pathological settings, it is essential to make direct, long-term assessments of blood pressure and blood flow under normal physiological conditions (ie in the conscious state).
In this presentation, Dr. McBryde shares insights from her studies of how the relationship between blood pressure and blood flow is altered in hypertension, to “consumer” organs such as the brain, and to “supply” circulations such as the mesenteric venous pool. She also discusses the variables that go into gathering accurate measurements of these two parameters in a lab setting.
Exploring Applied Physiology of the Cardiovascular System
The cardiovascular system is a cornerstone of human health, regulating the circulation of vital nutrients, oxygen, and waste products throughout the body.
Understanding the applied physiology of this system is essential for healthcare professionals to provide effective medical care and interventions.
Importance of Applied Cardiovascular Physiology
Effective healthcare requires a deep comprehension of how the cardiovascular system functions under various conditions.
Applied physiology knowledge empowers healthcare practitioners to make informed decisions, diagnose disorders, and formulate targeted treatment plans.
Focus on Practical Applications in Healthcare
This presentation delves into the practical aspects of cardiovascular physiology that directly impact clinical practice.
We will explore how physiological concepts are translated into real-world medical scenarios and interventions.
By grasping the applied physiology of the cardiovascular system, healthcare providers can optimize patient care, enhance diagnostics, and improve treatment outcomes.
Throughout this presentation, we'll bridge the gap between theoretical understanding and its practical implications in the field of healthcare.
Understanding the Components
The cardiovascular system comprises three crucial components: the heart, blood vessels, and blood.
Heart: A muscular organ that pumps blood, ensuring a continuous flow throughout the body.
Blood Vessels: A network of tubes that transport blood to and from various tissues.
Blood: A specialized fluid that carries nutrients, oxygen, hormones, and removes waste products.
Role in Oxygen and Nutrient Delivery
Oxygen from the lungs and nutrients from the digestive system are transported to body tissues through the bloodstream.
These essential components are required for cellular metabolism and energy production.
Scope: This subject is intended to impart the fundamental knowledge on various aspects
(classification, mechanism of action, therapeutic effects, clinical uses, side effects and
contraindications) of drugs acting on different systems of body and in addition,emphasis
on the basic concepts of bioassay. Objectives: Upon completion of this course the student should be able to
1. Understand the mechanism of drug action and its relevance in the treatment of
different diseases
2. Demonstrate isolation of different organs/tissues from the laboratory animals by
simulated experiments
3. Demonstrate the various receptor actions using isolated tissue preparation
4. Appreciate the correlation of pharmacology with related medical sciences
This lecture was presented to nursing students undertaking their bridging course at Nursing Training Institute of Technology (NTIT), Eenhana, Campus, Ohangwena Region, Namibia.
It discusses the transport system in humans, touching on topics like the heart, blood vessels, lymphatic system, and immunity in Biology. The resources used were the Namibian Namcol new curriculum for grade 10-11 ordinary level biology text book.
It was presented by myself, Dr. Nghitukuhamba Tangi Elikana Kalipi
MBChB, Bsc HB.
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
QA study - To improve the 6th monthly recall rate post-comprehensive dental treatment under general anaesthesia in paediatric dentistry department, Hospital Melaka
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
We understand the unique challenges pickleball players face and are committed to helping you stay healthy and active. In this presentation, we’ll explore the three most common pickleball injuries and provide strategies for prevention and treatment.