This document discusses alcohol use and misuse in the workplace. It defines substance misuse problems as regular or intermittent substance use that interferes with work performance or relationships. Dependence is difficulty controlling intake and withdrawal symptoms when reducing intake. The document provides blood alcohol concentration levels and associated accident risks. It lists some health hazards of heavy drinking like dementia and seizures. Diagnosis of alcoholism can involve liver enzyme tests. The WHO AUDIT screening test is described to assess alcohol use disorders.