The Air Force trains special operations fighters at Lackland Air Force Base using intensive human performance monitoring and analysis. Trainees undergo eight weeks of exercises tracked by sensors measuring their physiology, sleep, nutrition and biomechanics. The goal is to identify weaknesses and calibrate trainees to optimal performance levels using technology similar to professional athletics. The article describes the author's experience being monitored, revealing flaws in his posture and fitness. While humiliating, it demonstrates how the program aims to transform trainees' bodies and minds for the mental and physical demands of special operations.
Safety is not a matter isolated incidents but attitudes, behaviors and personality traits. Certain known clusters of behaviors coalesce into personalities that scare experts (and lead to accidents)
Safety is not a matter isolated incidents but attitudes, behaviors and personality traits. Certain known clusters of behaviors coalesce into personalities that scare experts (and lead to accidents)
Small Arms Lethality variables 1.6e DRAFTJA Larson
small arms lethality is a complex equation.
military operations are generally a team event.....more like football or soccer than tennis......
therefore teamwork and safety adds complexity
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Small Arms Lethality variables 1.6e DRAFTJA Larson
small arms lethality is a complex equation.
military operations are generally a team event.....more like football or soccer than tennis......
therefore teamwork and safety adds complexity
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
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What Happened When I Trained with Air Force Human Performance
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Military elite treat their bodies like high-performance race cars. Which is great—unless you show up to meet them in a hoopty.
By Joe Pappalardo Feb 12, 2019
JOHNNY SALDIVAR
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Joe Pappalardo visited Lackland for a story about the new ways the U.S. Air Force trains special-ops fighters. Check out the feature
here.
LACKLAND AIR FORCE BASE, TX—I knew that I was in trouble when I saw the mannequin. It’s ripped with the abs of Brad Pitt in Fight Club,
and despite the lack of legs it’s the most intimidatingly conditioned dummy I’ve ever seen.
The musclebound torso before me wears nothing but a wristband and a chest strap supporting a sensor the size and shape of a hotel bar of
soap. The gear measures the human body’s performance—more specifically, the exertions of young airmen at the U.S. Air Force Special Warfare
Training Wing. The dummy is used to introduce them to the equipment they will wear when they run and workout, producing data that will
scrutinize them like they’ve never been scrutinized before.
The mission at this facility at Lackland Air Force Base is deceptively simple: to get trainees ready for their first special-operations training class,
an unforgiving session called Assessment and Selection. Airmen must pass A&S to do Air Force jobs that involved deploying with ground forces.
Think of pararescue operators who leap out of aircraft or tactical controllers who call in close air support. Popular Mechanics got a behind-the-
scenes tour of this facility, which is applying the technology used in professional athletics to military training.
THE HUMAN BODY IS A MACHINE TO BE QUANTIFIED AND CALIBRATED TO AN OPTIMAL STATE.
To the instructors here in Texas, the human body is a machine to be quantified and calibrated to an optimal state. An eight-week course uses
sensors, intensive exercise, classwork, and shrewd mentorship to peel back the human body and mind, and expose any weakness. Trainees
have their central nervous system, hormone levels, and sleep cycles tracked. They give urine samples, perform in front of motion-capture video,
and see their plates of food scrutinized by nutritionists. They are assigned to hot tubs, cold baths, sensory-deprivation chambers, yoga poses,
whatever it takes to help recover from each day’s six hours of workouts and swims.
The mannequin is a perfect specimen, and a not-so-subtle cue to the trainees. This is what we expect. Which is why I start to regret requesting
to be subjected to as many pieces of monitoring equipment as time allows.
The Slouch of Modern Life Must Be CorrectedThe Slouch of Modern Life Must Be Corrected
To improve, the trainees must first be shown where they are deficient. So when they arrive, they enter the Dari Motion Capture system,
something similar to what Hollywood uses to fuse actors with their CGI characters. Dari doesn’t use on-body sensors, just cameras that capture
the biomechanical motions of subjects.
When I enter, a monitor mounted in the room shows an overlay over my body, something that looks like an artist’s stick model that moves when I
do. I immediately start doing The Robot—at least, until Rachel Matson, the athletic trainer with the squadron, instructs me to stand still with my
arms crooked downward.
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Technology Is Changing How We Train Elite FightersTechnology Is Changing How We Train Elite Fighters
Motion-capture lab.
JOHNNY SALDIVAR
Things go okay, at least until I’m asked to squat while holding a rod behind my head. The stick man on the screen twists unnaturally, out of
balance and crooked, looking awkward and clumsy, revealing the hidden history of my body (I had shoulder surgery years ago and have steadily
ignored rehabilitation exercises).
A conversation with Chief Master Sgt. Joshua Smith, an instructor with the 350th Special Warfare Training Squadron, doesn’t make me feel
better. The body’s strength is maximized when the spine is straight and there are muscles that hold the chest out.
“These days you can see the slouch, from modern life,” he says, speaking of the concave bends in the spine he sees in recruits. And
professional writers.
It makes me feel subpar and subhuman. And worse is to come.
Turns Out, I Am Not Built Like the Mannequin
As the aspirational mannequin demonstrated, the trainees wear a wristband and chest harness during all runs and non-pool workouts. The
stream of data warns of heat exhaustion (via a thermometer) and bad running form (via accelerometers). But its true purpose is to show,
empirically and in cold numbers, whether the subject is really pushing his or her limits. The whole point of being here is to find those limits and
then exceed them.
Stupidly, I have asked to try everything, so the crew at Lackland decides to “puck me up” with the Zephyr tracking system, which is available off
the shelf and often used by sports teams. “Okay,” says Smith, who is built like an extra on the set of Vikings. “Take off that shirt and we’ll hook
you up.”
I groan at the thought. I’m not built like the mannequin—more like if someone melted the mannequin with a giant magnifying glass.
You can’t cover the military without being okay with hanging around younger, better conditioned, and far more dangerously trained individuals
than yourself. But spending time with the special-operations community amplifies this divide. A much younger me once went on a steep ruck
march with an Army spec-ops team during training. I felt proud that I could almost keep up with one of them—until I learned he underwent hernia
surgery earlier that week.
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This place is something different. It’s one thing to be around the walking by-products of intense physical training, but quite another to be at a
place where such physicality is a guiding life principal. As I lay half-naked on the floor, I realize the degree that science can direct this fine-tuning.
The training wing is obsessed with mastering the cycles of exertion and recovery, and each student is pushed to figure out the best ways to
optimize their bodies. “This is just like an aircraft coming down and they hook up the computers to it and they download how well that aircraft
performed,” I remember Smith saying, earlier that day. “We're doing the same thing with these warriors we're developing.”
Data and Algorithms vs. Dedication and Grit
As I get bare for analysis, I glance around at the room to see if my self-consciousness is warranted. It is: a half-dozen subject-matter experts,
media affairs staff, and seasoned special warfare training staff are idly gawking. There’s even a photographer, contracted by the USAF, to
chronicle the stripping and wiring of the journalist.
Training with the chest strap.
JOHNNY SALDIVAR
The chest strap comes first. After a call for a “larger one,” Smith makes it work by tightening it, with hideous bulges the result. Still, the thing is
more comfortable than I’d imagine. I bet the trainees forget it’s even there as they suffer.
Harder to ignore is the electrode stuck to my forehead. Smith the Viking orders me to lay down and stay still and quiet. He’s taking some
baseline readings—heart rate, CNS, that sort of thing—to determine if I’m ready for a workout. This is part of an omega brain-wave reading,
determining if my brain has recovered enough of its electrical energy to handle the day’s exercise. (It turns out that it has.)
Laying half naked on the floor, surrounded by strangers and a pitiless photographer, I ponder this way of thinking. As may be typical, I measure
this experience against cultural icons.
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What would Captain America say about this place? Would he be disgusted to see data and algorithms superseding human guts, dedication, and
grit? Or would he understand that not everyone is built for front-line combat, in body or spirit, and anything that can be done to find and prepare
those that are is humane as well as efficient?
Steve Rodgers would probably recognize and appreciate something that seems familiar: These trainees are here to learn how to operate their
bodies like machines, but the choice to accept that discipline is theirs alone. They are volunteering for some of the hardest and stressful jobs in
the Air Force, and this course aims to calibrate their minds to accept what that means.
Trainees going for a run.
JOHNNY SALDIVAR
I remember what a trainee told me, earlier in the day: “In some ways it’s very structured here, and we’re watched closely. But now there’s also
more responsibility given to us.”
This helps contextualize my reaction, a little. Imagine I’m not a wreck of a writer in his 40s but a college baseball player with a heavy dose of
patriotism. The emotional impact of seeing exactly what’s wrong with my body would be a challenge, one that they are (hopefully) then taught
how to fix. If they can’t change their thinking—and adopt the kind of self-aware humility that does not come naturally to young alpha personalities
with competitive streaks—they won’t succeed in special operations.
So maybe Steve Rodgers wouldn’t get it. But Goose, despite the lack of warplanes, would understand it as the plot of Top Gun. Despite the
sensors, tight schedule, ever-present monitoring, military discipline, and streams of big data, this is one of the most human places I’ve visited.
Too bad it took my humiliation to drive the point home.
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Can the Air Force Learn To Love Startup Culture? The Army Wants to Block Troops’ Heat Signatures
Military Journal Claims Russian Troops Are Psychic This Bonkers Promo Could Be the Future of Warfare
DARPA Wants to Detect Submarines With Fish, Shrimp Critics Roast the Military’s Mini Nuclear Reactor
RESEARCH MILITARY TECHNOLOGY IS CHANGING HOW WE TRAIN ELITE FIGHTERS THE PLANES OF AIR FORCE SPECIAL OPS
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WE TRY TO DESTROY A $600 SPEC OPS WATCH
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