This document discusses a project using gene therapy and stem cell transplantation to cure HIV. It proposes using genome editing to disrupt the CCR5 gene in hematopoietic stem cells, which would then be transplanted into patients to generate an HIV-resistant immune system. An estimated 790 people with HIV-associated lymphomas in Russia per year could benefit from this treatment. The project founders have expertise in molecular biology, genome editing, stem cell transplantation, and treating HIV/AIDS and cancer patients.