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ADOPTING NEW
TECHNOLOGIES FOR
CERVICAL CANCER
PREVENTION
DISEASE PROGRESSION
2
WE CAN IDENTITY WOMEN AT RISK OF CERVICAL
CANCER BEFORE IT DEVELOPS
5 – 10 years
Vaccination HPV Testing Cytology and VIA Colposcopy
5-10 years
from
infection to
cancer
IMPACT OF 70% VACCINE COVERAGE OF WOMEN ON
CERVICAL CANCER DEATHS
3
PRIMARY PREVENTION
0
2
4
6
8
10
12
14
-10 0 10 20 30 40 50
TIME SINCE INTRODUCTION OF VACCINE (YEARS)
CERVICALCANCERDEATHS
(PER100,000PERYEAR)
WHO estimate the number of women with Cervical cancer will double by 2020, even with vaccination
SECONDARY PREVENTION: HPV TESTING
4
TECHNOLOGY
Screen with
HPV
Molecular
Test
Triage with
Cytology
Diagnose
with
Colposcopy
or Histology
Treat
VaccinateYoung Girls
• Detects existing
infection – the cause of
the disease
• Identifies women at risk
of cervical disease for
earlier treatment
• Used on women aged
30<
• Test every 3-5 years
WHY HPV DNA/RNA TESTING?
5
• Is more sensitive than cytology or VIA
• Detects lesions earlier for treatment
• Is a better predictor of risk for developing
cancer
• Detects clinically relevant levels of HPV
DNA and sub-types
• Provides longer term protection of 7+
years
• Cost effective - standardized, objective
• Self collection option - to extend coverage
Key Findings
• Reduction in cervical cancer
• Improved management of patients
• Objectivity – not dependent on human
interpretation
• Turnaround time – results in 1 day
• Opportunity to automate
• Opportunity to add self-sampling to increase
coverage
Benefits
• Almost 100% protection from a deadly
disease
• Single visit for HPV and cytology
• Possibility to take her own sample
Patients Benefits
SAFETY, REASSURANCE AND CONVENIENCE
PREVENTION STRATEGY
6
WORKING TOGETHER TO CREATE A CANCER FREE
WORLD
Vaccinatio
n
Improved
Screening
100%
Protection
THANK
YOU
Sebaka Molapo
nico.molapo1974@gmail.com
+2768-551-8758
QUALITY ASSURANCE SPECIALIST

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Adopting new technologies for cervical cancer prevention

  • 2. DISEASE PROGRESSION 2 WE CAN IDENTITY WOMEN AT RISK OF CERVICAL CANCER BEFORE IT DEVELOPS 5 – 10 years Vaccination HPV Testing Cytology and VIA Colposcopy 5-10 years from infection to cancer
  • 3. IMPACT OF 70% VACCINE COVERAGE OF WOMEN ON CERVICAL CANCER DEATHS 3 PRIMARY PREVENTION 0 2 4 6 8 10 12 14 -10 0 10 20 30 40 50 TIME SINCE INTRODUCTION OF VACCINE (YEARS) CERVICALCANCERDEATHS (PER100,000PERYEAR) WHO estimate the number of women with Cervical cancer will double by 2020, even with vaccination
  • 4. SECONDARY PREVENTION: HPV TESTING 4 TECHNOLOGY Screen with HPV Molecular Test Triage with Cytology Diagnose with Colposcopy or Histology Treat VaccinateYoung Girls • Detects existing infection – the cause of the disease • Identifies women at risk of cervical disease for earlier treatment • Used on women aged 30< • Test every 3-5 years
  • 5. WHY HPV DNA/RNA TESTING? 5 • Is more sensitive than cytology or VIA • Detects lesions earlier for treatment • Is a better predictor of risk for developing cancer • Detects clinically relevant levels of HPV DNA and sub-types • Provides longer term protection of 7+ years • Cost effective - standardized, objective • Self collection option - to extend coverage Key Findings • Reduction in cervical cancer • Improved management of patients • Objectivity – not dependent on human interpretation • Turnaround time – results in 1 day • Opportunity to automate • Opportunity to add self-sampling to increase coverage Benefits • Almost 100% protection from a deadly disease • Single visit for HPV and cytology • Possibility to take her own sample Patients Benefits SAFETY, REASSURANCE AND CONVENIENCE
  • 6. PREVENTION STRATEGY 6 WORKING TOGETHER TO CREATE A CANCER FREE WORLD Vaccinatio n Improved Screening 100% Protection