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Abdominal Pain
in Children
Updated 5/2/2015
Arjun Rao
+
Outline
 Clinical evaluation – tips and tricks
 Appendicitis
 Ovarian Torsion
 Intussusception
 “Constipation”
 Medical Causes
 Extra-abdominal causes
+
Epidemiology of Abdominal
Pain
 ~ 5% of all presentations to PED
 Surgery only required in 1-7%
 No specific diagnosis in up to 15%
+
History – the basics 1
 Maintain empathy at all times, no matter how tired
you are
 Parents are anxious and worried – don’t let this
frustrate you
 Open ended questions to start – let the parents
speak, don’t interrupt early
 Acknowledge that they might be exhausted,
especially if they have been transferred from
another hospital and have had a long day
 Age appropriate engagement of child
+
History – the basics 2
 History of pain – if child is old enough can ask
them
 Temporal history important
 Associated symptoms
 Red flags
 Bile stained vomiting
 Flank or back pain
 Waking at night
 Not walking
+
History – tips
 Ask about journey to hospital – when the car went
over bumps
 When asking about nature and severity let the
child know that the questions are hard and not to
worry too much if they can’t answer
 If the history is long try to establish if they had any
days when they were well
 Ask about stool frequency (beware assuming
“constipation”)
 Ask about family history of appendicits
+
Examination – the basics
 Distraction, be non-threatening, keep parents close
 Positioning
 Observation – RR (measure yourself), work of
breathing, movement, level of distress “well v
unwell”, Sa02 if monitored
 Vital signs – measure HR, CR
 All systems including ENT
 Inspection, Palpation, Percussion, Auscultation
+
Examination - tips
 Don’t stand over child, kneel or sit next to bed
 Keep arm horizontal, palpate with palm not tips of fingers
 Look at their face
 Distraction
 Ask about age, siblings, school, movies, parents, pets
 If you think the abdomen is distended measure
 Don’t forget hernia, testes
 Mobility, don’t be afraid to try to walk them but don’t push
+
Examination – the abdomen
Superficial palpation away from site of
reported pain – look at face
Deep palpation
Liver, spleen, kidneys
Masses
Percussion
+
Appendicitis in Children
 Most common non-traumatic surgical
emergency
 Peak 12-18 yrs
 Classic appendicitis easy
 “Atypical” appendicitis common in
children
 Beware false localising signs – diarrhoea,
dysuria
+
+
Appendicitis - Investigations
 No single diagnostic test
 Aim:
 high sensitivity/specificity
 minimise missed appendicitis
 minimise normal appendicectomy rate
 minimise delay to OT
+
Appendicitis - Investigations
• Urinalysis
– Pyuria in ~ 30%
• FBC
– Neither sensitive nor specific
• U/S
– Sensitivity 87%, Specificity 89%
– Not visualised 10%
• CT
– Sensitivity 91%, Specificity 94%
– RIM risk (single CT in 5yo -> 20-25:100000)
•Klein, M. D. (2007). "Clinical approach to a child with abdominal pain who might have appendicitis."
Pediatric Radiology 37(1): 11-14
•Doria, A. (2009). "Optimizing the role of imaging in appendicitis." Pediatric Radiology 39(Suppliment 2):
S144-148.
+ Appendicitis scores – Alvarado
Score
Clinical Feature Score
M Migration of pain to RIF 1
A Anorexia 1
N Nausea 1
T Tenderness in RLQ 2
R Rebound pain 1
E Elevated temperature 1
L Leukocytosis 2
S Shift to left of WBC 1
10
<5: Rule out
>7: Rule in
Probably - good at ruling out, not great at ruling in,
overestimates appendicitis in children with intermediate
scores
+
Intussusception
 Telescopic invagination of one
section of the bowel into
another
 Usually ileo-colic
 Can be a great “mimic”
Image Definition
http://yoursurgery.com
+
Intussusception
• Mostly idiopathic but consider lead point
• Vomit / pain / blood [classic triad < 30%]
• Most common 5-10mths – “any age”
• M:F 3:1, 1-4:1000
• X-ray may show signs
• US (sensitivity ~ 100%)
• Air enema
• Consider pathological lead point in very young or older
children
Del-Pozzo et al (1996). “Intussusception: US findings with pathologic correlation – the cresent in doughnut sign. Radiology
199: 688-792
+ Intussusception
Liver edge not well defined
“Cresent” in right upper quadrant
Paucity of gas on right side of abdomen
Distended loop of transverse colon
+
Meckel’s Diverticulum
• Omphalomesenteric duct vestige (vitelline duct)
• Contain gastric mucosa
• Can mimic appendicitis
http://www.health.act.gov.au
+
Meckel’s Diverticulum
 “Rule of 2s”
 2% population
 2% symptomatic (actually ~ 4%)
 2 inches long
 2 ft prox to terminal ileum
 2 times more common in boys
 2 types of ectopic tissue (gastric and pancreatic)
 Pain, bleed, perforation, obstruction
 Classic presentation -> painless bleeding
 Can be lead point for intussusception
 Meckel’s scan
 ~ 80% sensitivity, 95% specific
 Surgical excision
+
Ovarian Torsion
• Rare in children
• Usually seen with ovarian pathology
• Usually colicky lower pain
• Acute onset
• Right > Left
• May be associated nausea, vomiting,
raised WCC
• Ultrasound has high specificity /
sensitivity
+
Formulating a provisional and
differential diagnosis
 Be systematic
 Most likely to least likely
 Anatomical
 Most serious
 Surgical v Non-surgical
 Abdominal v extra-abdominal
Pnemonic
V Vascular
I Inflammatory/infectious
N Neoplastic
D Drugs
I Iatrogenic
C Congenital
A Autoimmune
T Traumatic
E Endocrine / Environmental
M Metabolic
+
Formulating a provisional and
differential diagnosis
 Constipation is not a diagnosis
 Rare but serious
 Discitis
 ALL
 Intra-abdominal abcess
 Tumour
 Anatomical approach
 Systems approach
+
Differential
Appendicitis
UTI/Pyelonephritis
Testicular torsion
Cholecystitis
Pneumonia
Pancreatitis
Intussusception
Bowel obstruction
Meckel’s Diverticulum
Poor diet -> constipation
http://www.lifescript.com
+
Extra-abdominal causes
• Tonsillitis / pharyngitis
• Pneumonia
• Pericarditis
+
“Medical” causes
• DKA
• HSP
• HUS
• Iron ingestion
• FMF
• Abdominal migraine
+
Neonates and Infants
• Hernia
• Torsion
• Appendicitis
• NEC
• Volvulus
• Intussusception
• Hirschprung
+
Management in ED - Analgesia
Assessment of pain
• Can be difficult – pain vs anxiety
• Age dependent
• Pain scales,Visual analogue scale
+
Management in ED - Analgesia
• Simple analgesia as appropriate
• Are opioids contra-indicated?
• No RCT
• Practice is to not withhold analgesia
• Intranasal Fentanyl (1-2mcg/kg)
• Intravenous Morphine (0.1-0.2mg/kg)
Sharwood, L. N. and F. E. Babl (2009). "The efficacy and effect of opioid analgesia in undifferentiated abdominal pain in
children: a review of four studies." Paediatric Anaesthesia 19(5): 445-451.
+
Disposition
 Admission v Discharge
 Solid plan for discharge and follow up
 “Obs admit” – try to avoid prolonged observation admission
 Admission for observation and serial examination is a good
option in equivocal cases
+
Guidelines
 SCH
 CHW
 RCH
 NSW Health
+
Essentials
1. Only a small percentage have surgical
cause
2. Age influences diagnostic possibilities
3. Abdominal examination critical
4. Don’t withhold analgesia
5. Aetiology may be intra or extra abdominal
6. Serial examination useful
7. Definitive diagnosis not always possible
8. Clear follow up important

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Abdo pain in children

  • 2. + Outline  Clinical evaluation – tips and tricks  Appendicitis  Ovarian Torsion  Intussusception  “Constipation”  Medical Causes  Extra-abdominal causes
  • 3. + Epidemiology of Abdominal Pain  ~ 5% of all presentations to PED  Surgery only required in 1-7%  No specific diagnosis in up to 15%
  • 4. + History – the basics 1  Maintain empathy at all times, no matter how tired you are  Parents are anxious and worried – don’t let this frustrate you  Open ended questions to start – let the parents speak, don’t interrupt early  Acknowledge that they might be exhausted, especially if they have been transferred from another hospital and have had a long day  Age appropriate engagement of child
  • 5. + History – the basics 2  History of pain – if child is old enough can ask them  Temporal history important  Associated symptoms  Red flags  Bile stained vomiting  Flank or back pain  Waking at night  Not walking
  • 6. + History – tips  Ask about journey to hospital – when the car went over bumps  When asking about nature and severity let the child know that the questions are hard and not to worry too much if they can’t answer  If the history is long try to establish if they had any days when they were well  Ask about stool frequency (beware assuming “constipation”)  Ask about family history of appendicits
  • 7. + Examination – the basics  Distraction, be non-threatening, keep parents close  Positioning  Observation – RR (measure yourself), work of breathing, movement, level of distress “well v unwell”, Sa02 if monitored  Vital signs – measure HR, CR  All systems including ENT  Inspection, Palpation, Percussion, Auscultation
  • 8. + Examination - tips  Don’t stand over child, kneel or sit next to bed  Keep arm horizontal, palpate with palm not tips of fingers  Look at their face  Distraction  Ask about age, siblings, school, movies, parents, pets  If you think the abdomen is distended measure  Don’t forget hernia, testes  Mobility, don’t be afraid to try to walk them but don’t push
  • 9. + Examination – the abdomen Superficial palpation away from site of reported pain – look at face Deep palpation Liver, spleen, kidneys Masses Percussion
  • 10. + Appendicitis in Children  Most common non-traumatic surgical emergency  Peak 12-18 yrs  Classic appendicitis easy  “Atypical” appendicitis common in children  Beware false localising signs – diarrhoea, dysuria
  • 11. +
  • 12. + Appendicitis - Investigations  No single diagnostic test  Aim:  high sensitivity/specificity  minimise missed appendicitis  minimise normal appendicectomy rate  minimise delay to OT
  • 13. + Appendicitis - Investigations • Urinalysis – Pyuria in ~ 30% • FBC – Neither sensitive nor specific • U/S – Sensitivity 87%, Specificity 89% – Not visualised 10% • CT – Sensitivity 91%, Specificity 94% – RIM risk (single CT in 5yo -> 20-25:100000) •Klein, M. D. (2007). "Clinical approach to a child with abdominal pain who might have appendicitis." Pediatric Radiology 37(1): 11-14 •Doria, A. (2009). "Optimizing the role of imaging in appendicitis." Pediatric Radiology 39(Suppliment 2): S144-148.
  • 14. + Appendicitis scores – Alvarado Score Clinical Feature Score M Migration of pain to RIF 1 A Anorexia 1 N Nausea 1 T Tenderness in RLQ 2 R Rebound pain 1 E Elevated temperature 1 L Leukocytosis 2 S Shift to left of WBC 1 10 <5: Rule out >7: Rule in Probably - good at ruling out, not great at ruling in, overestimates appendicitis in children with intermediate scores
  • 15. + Intussusception  Telescopic invagination of one section of the bowel into another  Usually ileo-colic  Can be a great “mimic” Image Definition http://yoursurgery.com
  • 16. + Intussusception • Mostly idiopathic but consider lead point • Vomit / pain / blood [classic triad < 30%] • Most common 5-10mths – “any age” • M:F 3:1, 1-4:1000 • X-ray may show signs • US (sensitivity ~ 100%) • Air enema • Consider pathological lead point in very young or older children Del-Pozzo et al (1996). “Intussusception: US findings with pathologic correlation – the cresent in doughnut sign. Radiology 199: 688-792
  • 17. + Intussusception Liver edge not well defined “Cresent” in right upper quadrant Paucity of gas on right side of abdomen Distended loop of transverse colon
  • 18. + Meckel’s Diverticulum • Omphalomesenteric duct vestige (vitelline duct) • Contain gastric mucosa • Can mimic appendicitis http://www.health.act.gov.au
  • 19. + Meckel’s Diverticulum  “Rule of 2s”  2% population  2% symptomatic (actually ~ 4%)  2 inches long  2 ft prox to terminal ileum  2 times more common in boys  2 types of ectopic tissue (gastric and pancreatic)  Pain, bleed, perforation, obstruction  Classic presentation -> painless bleeding  Can be lead point for intussusception  Meckel’s scan  ~ 80% sensitivity, 95% specific  Surgical excision
  • 20. + Ovarian Torsion • Rare in children • Usually seen with ovarian pathology • Usually colicky lower pain • Acute onset • Right > Left • May be associated nausea, vomiting, raised WCC • Ultrasound has high specificity / sensitivity
  • 21. + Formulating a provisional and differential diagnosis  Be systematic  Most likely to least likely  Anatomical  Most serious  Surgical v Non-surgical  Abdominal v extra-abdominal Pnemonic V Vascular I Inflammatory/infectious N Neoplastic D Drugs I Iatrogenic C Congenital A Autoimmune T Traumatic E Endocrine / Environmental M Metabolic
  • 22. + Formulating a provisional and differential diagnosis  Constipation is not a diagnosis  Rare but serious  Discitis  ALL  Intra-abdominal abcess  Tumour  Anatomical approach  Systems approach
  • 24. + Extra-abdominal causes • Tonsillitis / pharyngitis • Pneumonia • Pericarditis
  • 25. + “Medical” causes • DKA • HSP • HUS • Iron ingestion • FMF • Abdominal migraine
  • 26. + Neonates and Infants • Hernia • Torsion • Appendicitis • NEC • Volvulus • Intussusception • Hirschprung
  • 27. + Management in ED - Analgesia Assessment of pain • Can be difficult – pain vs anxiety • Age dependent • Pain scales,Visual analogue scale
  • 28. + Management in ED - Analgesia • Simple analgesia as appropriate • Are opioids contra-indicated? • No RCT • Practice is to not withhold analgesia • Intranasal Fentanyl (1-2mcg/kg) • Intravenous Morphine (0.1-0.2mg/kg) Sharwood, L. N. and F. E. Babl (2009). "The efficacy and effect of opioid analgesia in undifferentiated abdominal pain in children: a review of four studies." Paediatric Anaesthesia 19(5): 445-451.
  • 29. + Disposition  Admission v Discharge  Solid plan for discharge and follow up  “Obs admit” – try to avoid prolonged observation admission  Admission for observation and serial examination is a good option in equivocal cases
  • 30. + Guidelines  SCH  CHW  RCH  NSW Health
  • 31. + Essentials 1. Only a small percentage have surgical cause 2. Age influences diagnostic possibilities 3. Abdominal examination critical 4. Don’t withhold analgesia 5. Aetiology may be intra or extra abdominal 6. Serial examination useful 7. Definitive diagnosis not always possible 8. Clear follow up important

Editor's Notes

  1. Severity Constant Movement Radiation Nature – beware of putting words in their mouth
  2. Severity Constant Movement Radiation Nature – beware of putting words in their mouth There is some evidence of familial predisposition, especially in children under 6 yrs of age (Nelson Paediatrics). A prospective study found that children who ended up having appendicitis were more likely to have a first degree relative with appendicitis [1] 1.Gauderer MW, Crane MM, Green JA, DeCou JM, Abrams RS. Acute appendicitis in children: the importance of family history. J Pediatr Surg. 2001 Aug;36(8):1214–7.
  3. Normal appendicectimy rate previously accepted as ~ 10%, now ~ 2-5%
  4. RIM risk - a single abdominal CT study in a 5-year-old child, the lifetime risk of radiation-induced cancer would be 26.1 per 100,000 in female and 20.4 per 100,000 in male patients, based on probabilistic models designed with data from atomic bomb survivors WCC and inflammatory markers more likely to be elevated if long history
  5. Bowel segment invaginates into the lumen of the more distal lumen Invaginated segment carried more distally by peristalsis, mesentry and vessels squeezed -&amp;gt; venous congestion
  6. Specific lead point to consider -&amp;gt; meckels, HUS, CF, HSP, lymphoma/leukaemia [esp in children &amp;gt; 3 yrs]