This computational fluid dynamics study used simulations to analyze the effect of bend radius on erosion magnitude and location in an S-bend pipe carrying gas-solid or liquid-solid flows. Simulations were run for air velocities of 15.24-45.72 m/s and water velocities of 0.1-10 m/s, with particle sizes of 50-300 microns and bend radius to pipe diameter ratios (r/D) of 1.5, 2.5, and 3.5. Maximum erosion was found at certain velocity-particle size combinations and occurred at specific angle locations within each bend. The simulations aim to provide insight on erosion behavior to inform pipe design and operating conditions.