This document describes the orthodontic and surgical management of Zimmerman-Laband Syndrome. Zimmerman-Laband Syndrome is a rare genetic condition characterized by abnormalities of the nose and ears, nail and digit abnormalities, gingival fibromatosis, delayed dental eruption, skeletal anterior open bite, enlarged palatal rugae, and learning difficulties. The treatment plan involved upper and lower fixed appliances, 6mm posterior maxillary impaction with mandibular autorotation, finishing orthodontics, and retention with upper and lower retainers. Pre-treatment, post-operative, post-surgical, and debond photographs and radiographs are presented to document the treatment and outcomes.

1. School of Dentistry
Yr Ysgol Ddeintyddiaeth
The orthodontic and surgical
management of Zimmerman-Laband
Syndrome
Popat H, Perks T, Cronin AJ, Durning P, Maggs R.
Cardiff University School of Dentistry
Yr Ysgol Ddeintyddiaeth

2. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Zimmerman-Laband Syndrome
• First reported in 1928
• Only 39 cases worldwide
• Features:
– abnormalities of the nose and/or ears
– hypoplasia of the nails/terminal phalanges of the
hands and feet
– gingival fibromatosis
– delayed dental eruption
– skeletal anterior open bite
– enlarged palatal rugae
– learning difficulties

3. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Extra-oral Presentation

4. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Intra-oral Presentation

5. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Radiographic Presentation

6. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Pre- treatment cephalometric values

7. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Treatment Plan
• Upper sectional fixed appliance
• Lower continuous fixed appliance
• 6mm posterior segmental maxillary
impaction with autorotation of the
mandible
• Finishing orthodontics with upper and
lower continuous archwires
• Retention with upper and lower pressure
formed retainers

8. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Treatment simulation

9. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Post-operative extra- oral photographs

10. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Post-operative intra-oral photographs

11. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Cephalometric superimposition

12. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Post-surgical cephalometric analysis

13. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Debond extra-oral photographs

14. School of Dentistry
Yr Ysgol Ddeintyddiaeth
Debond intra-oral photographs