1. The study examined levels of cardiac troponin T and CK-MB in 155 patients within 24 hours of chest pain symptoms to diagnose myocardial infarction.
2. Patients were divided into 6 groups based on troponin T levels. Troponin T was found to be a more sensitive marker than CK-MB for detecting minimal myocardial injury.
3. In groups with moderately elevated troponin T, CK-MB levels remained similar to controls and were not proportional to troponin T increases. This indicates troponin T is better able to detect early myocardial damage not seen in CK-MB levels.
Diagnostic Efficiency and Prognostic Value of Troponin T Measurement in Acute...IJERA Editor
The diagnosis and prognosis of patients hospitalized with acute myocardial ischemia is quite variable. We examined the value of serum levels of cardiac Troponin T, serum CK-MB levels for detection of ischemic myocardial injury and risk stratification within 40 days in patients with acute myocardial ischemia with one specimen taken 2-8 hours of the onset of symptoms
Implication from thyroid function decreasing during chemotherapy in breast ca...Enrique Moreno Gonzalez
Thyroid hormones have been shown to regulate breast cancer cells growth, the absence or reduction of thyroid hormones in cells could provoke a proliferation arrest in G0-G1 or weak mitochondrial activity, which makes cells insensitive to therapies for cancers through transforming into low metabolism status. This biological phenomenon may help explain why treatment efficacy and prognosis vary among breast cancer patients having hypothyroid, hyperthyroid and normal function. Nevertheless, the abnormal thyroid function in breast cancer patients has been considered being mainly caused by thyroid diseases, few studied influence of chemotherapy on thyroid function and whether its alteration during chemotherapy can influence the respose to chemotherapy is still unclear. So, we aimed to find the alterations of thyroid function and non-thyroidal illness syndrome (NTIS) prevalence druing chemotherapy in breast cancer patients, and investigate the influence of thyroid hormones on chemotherapeutic efficacy.
Omics technology: an important tool in mechanism studies of Chinese herbal fo...LucyPi1
Identifying the active ingredients from natural herbal medicines and demonstrating their potential mechanisms are key points in the traditional Chinese medicine (TCM) field. In recent years, increasing studies have focused on the effects and mechanisms of Chinese herbal formulas. Basic studies on these formulas further coincide with the theory and practical use of TCM according to the clinical experiences for thousands of years. Single compounds have specific molecular structures; therefore, their methodologies in effect and mechanism studies are similar in both Western and Eastern medicines, making them more acceptable by researchers worldwide. On the contrary, the multicomponent, multitarget, and multipathway structures of Chinese formulas make it challenging to explore their mechanisms accurately where the routine method used in Western medicine studies would be inapplicable, which is the main reason for the unacceptance of Chinese herbal formulas by researchers worldwide and presents a huge obstacle to the modernization of TCM. With the rapid progress in basic TCM studies, scientific and technological innovations have achieved a breakthrough in TCM. Omic technology, a series of research methods based on high-throughput analysis and detection techniques in modern biological research system such as genomics, transcriptomics, proteomics, and metabolomics, evaluates thousands of targets and pathways rather than focusing on a single target or pathway and could screen the global changes in genes, proteins, metabolites, and other factors involved in the process of biological signaling transduction [1]. This is in agreement with the “holism” theory in TCM, which explains the overall mechanisms of Chinese herbal formulas comprehensively. In this study, we introduced the conventionally used omic technologies and their applications in research of mechanism studies of Chinese herbal formulas.
Diagnostic Efficiency and Prognostic Value of Troponin T Measurement in Acute...IJERA Editor
The diagnosis and prognosis of patients hospitalized with acute myocardial ischemia is quite variable. We examined the value of serum levels of cardiac Troponin T, serum CK-MB levels for detection of ischemic myocardial injury and risk stratification within 40 days in patients with acute myocardial ischemia with one specimen taken 2-8 hours of the onset of symptoms
Implication from thyroid function decreasing during chemotherapy in breast ca...Enrique Moreno Gonzalez
Thyroid hormones have been shown to regulate breast cancer cells growth, the absence or reduction of thyroid hormones in cells could provoke a proliferation arrest in G0-G1 or weak mitochondrial activity, which makes cells insensitive to therapies for cancers through transforming into low metabolism status. This biological phenomenon may help explain why treatment efficacy and prognosis vary among breast cancer patients having hypothyroid, hyperthyroid and normal function. Nevertheless, the abnormal thyroid function in breast cancer patients has been considered being mainly caused by thyroid diseases, few studied influence of chemotherapy on thyroid function and whether its alteration during chemotherapy can influence the respose to chemotherapy is still unclear. So, we aimed to find the alterations of thyroid function and non-thyroidal illness syndrome (NTIS) prevalence druing chemotherapy in breast cancer patients, and investigate the influence of thyroid hormones on chemotherapeutic efficacy.
Omics technology: an important tool in mechanism studies of Chinese herbal fo...LucyPi1
Identifying the active ingredients from natural herbal medicines and demonstrating their potential mechanisms are key points in the traditional Chinese medicine (TCM) field. In recent years, increasing studies have focused on the effects and mechanisms of Chinese herbal formulas. Basic studies on these formulas further coincide with the theory and practical use of TCM according to the clinical experiences for thousands of years. Single compounds have specific molecular structures; therefore, their methodologies in effect and mechanism studies are similar in both Western and Eastern medicines, making them more acceptable by researchers worldwide. On the contrary, the multicomponent, multitarget, and multipathway structures of Chinese formulas make it challenging to explore their mechanisms accurately where the routine method used in Western medicine studies would be inapplicable, which is the main reason for the unacceptance of Chinese herbal formulas by researchers worldwide and presents a huge obstacle to the modernization of TCM. With the rapid progress in basic TCM studies, scientific and technological innovations have achieved a breakthrough in TCM. Omic technology, a series of research methods based on high-throughput analysis and detection techniques in modern biological research system such as genomics, transcriptomics, proteomics, and metabolomics, evaluates thousands of targets and pathways rather than focusing on a single target or pathway and could screen the global changes in genes, proteins, metabolites, and other factors involved in the process of biological signaling transduction [1]. This is in agreement with the “holism” theory in TCM, which explains the overall mechanisms of Chinese herbal formulas comprehensively. In this study, we introduced the conventionally used omic technologies and their applications in research of mechanism studies of Chinese herbal formulas.
Clinical role of serum copeptin in acute coronary syndromeRamachandra Barik
our study revealed that Copeptin concentration is significantly higher in patients with AMI compared to patients with UA. Moreover, Copeptin rises at a time when other biomarkers namely the routinely used markers; cTns and CKMB are still undetectable.
Increased Cardiac Troponin T in Patients without Myocardial InfarctionYogeshIJTSRD
According to the World Health Organization, the diagnosis of acute myocardial infarction AMI is based on two of the three main criteria changes in the ECG up to 25 of myocardial infarctions are not reflected in the ECG , anginous pain, and increased markers of myocardial necrosis. In 2000, the European Scientific Society and the American College of Cardiology made a correction to the definition of AMI, according to which the determining factor in the diagnosis of AMI is the detection of an increased level of specific markers of myocardial necrosis — cardiac troponins in the blood. Troponin is a protein that is part of myofibrils. Cardiac troponin contains three subunits T, I, and C. Troponin C is non specific for the myocardium, in contrast to the T and I subunits, whose structure in the contractile fibers of cardiomyocytes differs from similar proteins of other muscle cells. The widespread use of the determination of cardiac troponins in the blood significantly increased the detection of AMI by 30 200 . Until recently, it was believed that troponins enter the blood only as a result of the death of cardiomyocytes. However, in recent years, it has been shown that troponins can penetrate into the interstitial space, and then into the blood, when cardiomyocytes are damaged with an increase in the permeability of their cell membranes, which can be caused not only by AMI, but also by conditions accompanied by hyper production of pro inflammatory cytokines tumor necrosis factor a, interleukin 1, etc. . The aim of this study was to analyze the final diagnoses in patients with increased cardiac troponin T levels without a clinical picture and characteristic ECG changes in AMI. Khusainova Munira Alisherovna "Increased Cardiac Troponin-T in Patients without Myocardial Infarction" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Special Issue | Innovative Development of Modern Research , April 2021, URL: https://www.ijtsrd.com/papers/ijtsrd40034.pdf Paper URL : https://www.ijtsrd.com/medicine/other/40034/increased-cardiac-troponint-in-patients-without-myocardial-infarction/khusainova-munira-alisherovna
Src jbbr-20-120 Dr. ihsan edan abdulkareem alsaimary PROFESSOR IN MEDICAL M...dr.Ihsan alsaimary
Dr. ihsan edan abdulkareem alsaimary
PROFESSOR IN MEDICAL MICROBIOLOGY AND MOLECULAR IMMUNOLOGY
ihsanalsaimary@gmail.com
mobile : 009647801410838
university of basrah - college of medicine - basrah -IRAQ
Prothrombin Time/International Normalized Ratio and Thrombelastography Discor...Arthur Stem
The utility of conventional coagulation assays, such as the prothrombin time/international normalized ratio (PT/INR), for assessing coagulopathy in severely injured patients has been questioned. This is particularly true in the setting of discordant results against thrombelastography (TEG). Thrombin generation (TG) offers a unique mechanism to analyze discordances between PT/INR and TEG, given its global assessment of the end-product of the coagulation cascade. The ability to correlate PT/INR with TG is additionally important, as recent literature suggests transfusion of fresh frozen plasma based on an elevated PT/INR alone is linked to increased mortality in the setting of traumatic brain injury. We hypothesize that PT/INR reflects thrombin generation but, in the setting of a normal TEG, does not reflect altered hemostatic capacity.
MI is one of the CVS complication leading to mortality whose diagnosis is mainly dependent on clinical presentation and other supportive investigation. clinical laboratory plays crucial role in its diagnosis, prognosis and monitoring therapy.
Clinical role of serum copeptin in acute coronary syndromeRamachandra Barik
our study revealed that Copeptin concentration is significantly higher in patients with AMI compared to patients with UA. Moreover, Copeptin rises at a time when other biomarkers namely the routinely used markers; cTns and CKMB are still undetectable.
Increased Cardiac Troponin T in Patients without Myocardial InfarctionYogeshIJTSRD
According to the World Health Organization, the diagnosis of acute myocardial infarction AMI is based on two of the three main criteria changes in the ECG up to 25 of myocardial infarctions are not reflected in the ECG , anginous pain, and increased markers of myocardial necrosis. In 2000, the European Scientific Society and the American College of Cardiology made a correction to the definition of AMI, according to which the determining factor in the diagnosis of AMI is the detection of an increased level of specific markers of myocardial necrosis — cardiac troponins in the blood. Troponin is a protein that is part of myofibrils. Cardiac troponin contains three subunits T, I, and C. Troponin C is non specific for the myocardium, in contrast to the T and I subunits, whose structure in the contractile fibers of cardiomyocytes differs from similar proteins of other muscle cells. The widespread use of the determination of cardiac troponins in the blood significantly increased the detection of AMI by 30 200 . Until recently, it was believed that troponins enter the blood only as a result of the death of cardiomyocytes. However, in recent years, it has been shown that troponins can penetrate into the interstitial space, and then into the blood, when cardiomyocytes are damaged with an increase in the permeability of their cell membranes, which can be caused not only by AMI, but also by conditions accompanied by hyper production of pro inflammatory cytokines tumor necrosis factor a, interleukin 1, etc. . The aim of this study was to analyze the final diagnoses in patients with increased cardiac troponin T levels without a clinical picture and characteristic ECG changes in AMI. Khusainova Munira Alisherovna "Increased Cardiac Troponin-T in Patients without Myocardial Infarction" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Special Issue | Innovative Development of Modern Research , April 2021, URL: https://www.ijtsrd.com/papers/ijtsrd40034.pdf Paper URL : https://www.ijtsrd.com/medicine/other/40034/increased-cardiac-troponint-in-patients-without-myocardial-infarction/khusainova-munira-alisherovna
Src jbbr-20-120 Dr. ihsan edan abdulkareem alsaimary PROFESSOR IN MEDICAL M...dr.Ihsan alsaimary
Dr. ihsan edan abdulkareem alsaimary
PROFESSOR IN MEDICAL MICROBIOLOGY AND MOLECULAR IMMUNOLOGY
ihsanalsaimary@gmail.com
mobile : 009647801410838
university of basrah - college of medicine - basrah -IRAQ
Prothrombin Time/International Normalized Ratio and Thrombelastography Discor...Arthur Stem
The utility of conventional coagulation assays, such as the prothrombin time/international normalized ratio (PT/INR), for assessing coagulopathy in severely injured patients has been questioned. This is particularly true in the setting of discordant results against thrombelastography (TEG). Thrombin generation (TG) offers a unique mechanism to analyze discordances between PT/INR and TEG, given its global assessment of the end-product of the coagulation cascade. The ability to correlate PT/INR with TG is additionally important, as recent literature suggests transfusion of fresh frozen plasma based on an elevated PT/INR alone is linked to increased mortality in the setting of traumatic brain injury. We hypothesize that PT/INR reflects thrombin generation but, in the setting of a normal TEG, does not reflect altered hemostatic capacity.
MI is one of the CVS complication leading to mortality whose diagnosis is mainly dependent on clinical presentation and other supportive investigation. clinical laboratory plays crucial role in its diagnosis, prognosis and monitoring therapy.
Baseline Analysis of PXT3003 Phase 2 Data Reveals Two Blood Early Candidate B...Pharnext
Charcot-Marie-Tooth disease Type 1A (CMT1A) is a rare inherited peripheral neuropathy associated with duplication of the gene encoding the peripheral myelin protein PMP22. Patients develop slowly progressive, distally pronounced muscle atrophy along with weakness, walking disability and sensory defect.
Despite promising experimental data, following therapy trials based on acid ascorbic intake failed (Verhamme et al. 2009, Micallef et al. 2009, Burns et al. 2009, Toth 2009, Pareyson et al. 2011, Lewis et al. 2013). Beside the observed lack of efficacy, it has been hypothesized that established clinical outcome measures might not be sensitive enough to detect short-term amelioration within preliminary studies. Therefore, discovery of surrogate biomarkers of disease severity are urgently needed.
Assessment of immunomolecular_expression_and_prognostic_role_of_tlr7_among_pa...dr.Ihsan alsaimary
Dr. ihsan edan abdulkareem alsaimary
PROFESSOR IN MEDICAL MICROBIOLOGY AND MOLECULAR IMMUNOLOGY
ihsanalsaimary@gmail.com
mobile : 009647801410838
university of basrah - college of medicine - basrah -IRAQ
Copeptin as a Novel Biomarker in the Diagnosis of Acute Myocardial Infarction...Premier Publishers
To evaluate the diagnostic value of Copeptin as a novel biomarker in early diagnosis of Acute Myocardial Infarction. 56 patients with acute Myocardial Infarction (STEMI) and 25 healthy controls who were admitted to the Cardiology and Clinical Pathology Departments, national heart institute (NHI) from October 2015 to April 2016. The kit used a double-antibody sandwich enzyme-linked immune-sorbent assay (ELISA) to assay the level of Human Copeptin in samples. As regard copeptin, the median range of copeptin level was 242.5pg/ml in patient group and 75pg/ml in control group. The comparative study between the two groups shows a significant difference (p < 0.05) Conclusion: Copeptin is a reliable diagnostic tool in patients with AMI (STEMI) with sensitivity 85.7%, specificity 86.7%, PPV 96% and NPV 61.9%.
Cycloartanes from Tabernaemontana coronaria (Jacq) Willd flowers with their c...Akhil Gupta
The n-hexane fraction of Tabernamontana coronaria (Jacq) Willd flowers afforded two cycloartane type triterpenes, cycloart-25-en-3β, 24 diol and cycloart-23-en-3β, 22α, 25triol for the first time from this plant, in addition to lupeol acetate, α-amyrin, cycloeucalenol, stigmasterol.
In vitro antioxidant, antimicrobial and cytotoxic activities of the various e...Akhil Gupta
The present study was designed to investigate antioxidant, antimicrobial and cytotoxic potential of pet ether, chloroform and methanol extracts of Ganoderma lucidum available in Bangladesh.
Histophysiology and Histochemical Analysis of the Saccus Vasculosus of Butter...Akhil Gupta
Cellular details including histochemical nature and functional aspects of saccus vasculosus in Ompok bimaculatus (Bloch, 1794) were studied using histological and histochemical techniques. The oval protruded saccus vasculosus
situated on the ventral side of the diencephalon behind the pituitary. This circumventricular organ contained atypical large central lumen lined by single stratified ithelium with characteristic coronet cells and supporting cells.
Silver stain was adopted for the occurrence and distribution of neurons if any in the epithelium and various regions
of the saccus vasculosus. Intensity of glycogen was found to be associated with the coronet cells and blood vessels.
Histochemical localization of basic protein and bound lipid were recorded in the cells of saccus epithelial lining as
well as in the blood vessels. Coronet cells perhaps involved in secretory as well as sensory function of the fish concerned.
1. ISSN 2320-7078
Volume 1 Issue 3
Online Available at www.entomoljournal.com
Journal of Entomology and Zoology Studies
Vol. 1 No. 3 2013 www.entomoljournal.com Page | 29
Troponin T as the Best Biochemical Markers in the
Detection of Myocardial Infarction.
Merije Elezi 1*
, Anila Mitre 2
, Tefta Rexha 3
1. State University of Tetovo, Faculty of Food Technology and Nutrition, Gostivar, Macedonia.
[E-mail: merijeelezi@gmail.com; Tel: +389 70 487302]
2. State University of Tirana, Faculty of Natural and Mathematical Sciences, Department of Biology,
Molecular Biology Section, Tirana, R. Albania, University Hospital “Mother Theresa”, Albania.
3. State University of Tirana, Faculty of Natural and Mathematical Sciences, Department of Biology,
Molecular Biology Section, Tirana, R. Albania.
We examined the value of serum levels of cardiac troponin T, serum creatine kinase MB (CK-MB) in the 155
patients within 24 hours of the onset of symptoms, presenting to the University Hospital “Mother Theresa” with a
history of one or more episodes of angina and ECG confirmation of MI by the cardiologist. In preliminary
observations, we found that the quantum of increase in troponin-T was disproportionate to that of CK-MB. This
study was conducted in 6 different groups based on the level of serum troponin T. It was determined by means of a
third generation assay (sandwich immuno assay) based on electrochemiluminescence (Elecsys, Roche Diagnostics).
CK-MB was also determined on Coobas (Roche Diagnostics). According to the methods employed, control
population should have troponin T levels <0.010 ng/ml and CKMB< 20U/L. Patients with symptoms of angina had
significantly higher troponin-T and CK-MB levels when compared to healthy controls (P<0.001). In the group 3
with 33 patients the troponin-T value (0.1-1.9mg/ml), p=0.363 (r=0.363 ). The value of TNT were not
proportionately elevated with CK-MB value (5.8-18.2U/L), p=0.018 (r=0.338). In cases of severe heart attack
myocardial coefficient of correlation between two parameters under consideration resulted r = 0.954, with
signifikance P<0.01. cases of severe heart attack myocardial coefficient of correlation between two parameters
under consideration resulted r = 0.954, with signifikance P<0.01. Troponin-T levels can be used to detect early and
minimal myocardial injury, but CK-MB is not sensitive enough to diagnose this. Initial troponin-T determination
drawn at the time of the patients’ presentation is a powerful diagnostic tool for a rapid diagnosis rather than serial
CKMB determination.
Keyword: TNT,CKMB, Angina Pectoris, Significantly , Electrochemioluminescence
1. Introduction
Troponin T is a very specific test compared with
other tests such as CK-MB in identifying patients
at risk for developing and managing their cardiac
necrosis.
of myocardial necrosis can be identified through
blood liberation of various proteins, as a result of
damage to myocites: Myoglobin, cardiac
Troponin I and T, creatine kinase (CK-MB),
lactate dehydrogenasa many other (Elisabeth).
Better biomarkers currently estimated cardiac
Troponin (T and I), which has nearly absolute
specificity, high sensitivity and enables the
identification of microscopic necrosis. If troponin
tests are not possible, alternative second best is to
measure the level of CK-MB's. This analysis is
less specific. The values of total CK is not
recomended for routine diagnosis of IM, because
the distribution of this enzyme has large tissues.
Evaluation of a repeat infarction also is
2. Journal of Entomology and Zoology Studies
Vol. 1 No. 3 2013 www.entomoljournal.com Page | 30
important as it gives information on the added
risk to the patient (Jeremiah). However infarckt
repeat is difficult to diagnose because troponin
levels may remain high for a long time, which
makes it impossible to determine the second
approximation infarction.
2. The Material and Working Method
During the period 2010-2011 are set Troponin
values T and CK-MB in 155 patients submitted
for examination in the cardiology clinic of
University Hospital Center "Mother Teresa" in
Tirana, with initial diagnosis of angina pectoris
(chest pain). All patients were aged 53-75 years,
of whom 93 were males and 62 females. After
completion of consultation with the cardiologist,
ECG examinations were performed at the Tirana
University Hospital Center and biochemical
Troponin T and CK-MB. For analysis venous
blood was obtained through flebotom tubes. All
examinations were performed within 2 hours of
receiving the blood of patients. Troponin T is
determined by measurements of third generation
(sandwich immunological measurement) based
on the principle of electrochemioluminescence
(Cobas apparatus 6000, Roche Diagnostic) That
uses human cardiac Troponin T recombinantly
as a reference standard. CK-MB also determined
in the Cobas 6000.
Together with the examination of biochemical
parameters in patients above, we realized the
measurement of these two parameters in a group
of 50 normal individuals who control it as like a
vacation. These are individuals who are
submitted to the clinic to carry out a check-up-I,
whose responses were normal. This group was
chosen to determine normal values of CK-MB
and Troponines T in our population according to
the instructions of Roche Company, who rates it
recommends addition, each country or laboratory
in accordance with its specifications, determine
normal values in the population.
3. Results
Troponin T is the most powerful marker, the
sensitivity and specificity independently with the
highest in the diagnosis of myocardial infarction.
It is able to determine the minimal myocardial
heart attacks which can not do markers used so
far as CK-MB and ECG has. Diagnosis
performed by this marker is not only correct but
also quicker.
4. Results and Discussion
Patients received the study were 155 of which
60% were male and 40% female. Troponin levels
in them ranged from <0.01 mg / ml to 24.67 mg /
ml and CK-MB values from 1.09 to 729.320-U /
L (Tab 1). For ease of processing, values <0.01
were recorded as 0.009 mg / ml.
Table 1: Values of troponin T and CK-MB in the control group and patients with angina pectoris.
Parameter
Control
(N = 50)
Patients
(N = 155)
Troponin T (mg/ml) 0.009 – 0.03 0.009 – 24.67
CK-MB (U/L) 1.09 – 16.45 1.007 – 729.320
For convenience of study, since the number of
patients is large and there are a variety of values,
we have split into six groups, taking into account
levels of Troponines T as in the following table
(Tab 2). In addition to these six groups troponin
values are also set the respective values of CK-
MB-
3. Journal of Entomology and Zoology Studies
Vol. 1 No. 3 2013 www.entomoljournal.com Page | 31
Table 2: Grouping of patients according to the level of blood troponines.
Group I II III IV V VI
Troponin
(mg/ml)
<0.03 0.03-0.1 0.1-1.9 1.9-4.1 4.1-7.3 7.3-24.67
CK-MB
(U/L)
1.007-10.73 3.12-7.41 5.8-18.12 14.02-68.12 45.91-235.09 168.98- 729.32
No. Patients 83 11 33 8 3 17
Table 1: Appearance frequency of each group.
The first group includes those patients who are
characterized not only by low levels of troponin,
but also by low levels of CK-MB of blood. By
examining elektrokardiografik and cardiology
consultations, test results fall after initial
diagnosis with which they were presented at the
cardiology clinic. Exclude this group of patients
from the study because the entity arising out of
our study.
The second group includes those patients in
whom T troponin levels are much less mature,
but not really related to cardiac necrosis. The
reason for the increase of T Troponin trumpet
comes from the formation of a plaque
arthrosklerotike destroyed. The appearance of
increased levels of troponin trumpet cardiac
moderately. This is due to the destruction of the
left artery circulation (Tucher).
The third group represents the largest group of
cases with cardiac problems, provides patients
with pathological values Troponin T, and CK-
MB values are unchangeable. In order to prove
that Troponin level changes between control
group and third group are significant, we realized
the statistical processing of correlation Sperman
by SPSS program [3]
. It realized the same thing
for CK-MB-in.
Concerning the possible correlation of CK-MB
levels and Troponin T between the third and the
control, the statistical processing of data obtained
showed that: significant between control group
and third group troponin T, resulting the value p
= 0.363, coefficient value of correlation r = 0.33,
which shows no correlation between them. For
this group Troponines T values are very different
from the control group. Otherwise occurs in the
case of comparing the values of CK-MB of the
0
10
20
30
40
50
60
70
80
90
Group
I
Group
II
Group
III
Group
IV
Group
V
Group
VI
Frequency of
group
4. Journal of Entomology and Zoology Studies
Vol. 1 No. 3 2013 www.entomoljournal.com Page | 32
third group with those of CK-MB of the control
group, where r = 0.338 and P= 0.018 significant
of order (P<0.05) . While Troponines T levels
rise above the norm up to 1.9 mg / ml, CK-MB
values remain similar to those of the control
group. Precisely this is the group which emerges
more Troponin T value compared to CK-MB-in.
While Troponina T is able to detect minimal
myocardial heart attacks, CK-MB has not been
able to do it (Elisabeth). If we had used only the
analysis of CK-MB of only as a diagnostic
criterion for assessing the degree of myocardial
damage, 21.29% (33/155) of cases had not been
diagnosed (found). T Troponins analysis enabled
diagnosis and appropriate therapy, helping direct
their quality of life.
In the fourth group we compared the values of
CK-MB and T Troponin respective control
groups. The processing of data obtained turned
out: the value of P= 0.244 troponin and r = -
0.334, while for CK-MB P= 0.632 and r = 0.140.
In the group of fifth and sixth, based on
significantly increased levels Troponin T and
CK-MB, compared with control groups, to look
beat porting the correlation between these levels,
the computed value of the correlation coefficient .
In cases of severe heart attack myocardial
coefficient of correlation between two parameters
under consideration resulted r = 0.954, with
significance P<0.01. This shows that the level of
troponin -T, powerful correlated CK-MB level in
these two groups.
5. References
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targets cardiac injury” Learn about levels so
you can give your patient the best possible care.
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McCabe H. sCardiac specific Troponin I levels to
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performance and prognostic values of serum
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Arveiler D, Rajakangas A, Pajak A. Myocardial
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