Dr. Md. Nazmus Sakib discusses the history and management of septicemia. Key points include that Ignaz Semmelweiss first introduced hand washing to reduce childbirth mortality, Alexander Fleming discovered penicillin in 1928, and the Sepsis Six bundle recommends giving IV fluids, antibiotics, and oxygen and monitoring output while taking blood cultures, full blood counts, and lactate levels to reduce sepsis mortality. Septicemia occurs when bacteria enter the bloodstream from an infection and cause systemic symptoms, and if not promptly treated can lead to septic shock and multiple organ dysfunction syndrome.