Simultaneous Safety: Purposeful Physiological Monitoring
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The document discusses developing a prototype to simultaneously monitor multiple physiological signals like heart rate, breathing rate, temperature, and oxygen saturation from children to determine if they are well or unwell. It mentions collecting and validating data from the prototype, conducting external validation, and distributing and marketing the prototype with the vision of using it to simultaneously monitor safety and save lives and resources.
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FCPS Physiology
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MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
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Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
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Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
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Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
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Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
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Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
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Charaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
Charaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
Simultaneous Safety: Purposeful Physiological Monitoring
- 1. Simultaneous Safety…. …Purposeful physiological detection Dr. Damian Roland (@damian_roland)
- 2. Is this child….. Well or unwell?
- 3. What about this one….. Well or unwell?
- 4. and finally this….. Well or unwell?
- 5. Critical Observations Heart Rate Breathing Rate Temperature Oxygen Saturations
- 10. And now for something I prepared earlier…..
- 11. What would a million pounds do…
- 12. Developmental Prototype What would a million pounds do…
- 13. Developmental Prototype Data collection and validation … What would a million pounds do…
- 14. Developmental Prototype Data collection and validation External Validation What would a million pounds do…
- 15. Developmental Prototype Data collection and validation External Validation Distribution and Marketing What would a million pounds do…
- 16. “Vision without action is merely a dream. Action without vision just passes the time. Vision with action can change the world.” - Joel A Barker What would a million pounds do… Simultaneous Safety: Save lives, Save resources