This document provides information about syphilis from the National University School of Human Medicine in Lambayeque, Peru. It discusses the causative bacterium Treponema pallidum, stages of syphilis infection including primary, secondary, and congenital syphilis. It also describes clinical signs such as painless ulcers, rashes, and mucous patches. The document provides guidance on diagnosing syphilis through physical examination, darkfield microscopy, PCR testing, and biopsy of lesions.

1. NATIONAL UNIVERSITY
Pedro Ruiz Gallo
HUMAN MEDICINE SCHOOL
Lambayeque, September 2012

2. Pedro Ruiz
Gallo
NATIONAL UNIVERSITY
TEACHER:
TEAM:
Dra. Rosa Gonzales Llontop
Nº 03
CURSE:
Medical English
STUDENTS:
Carlos Elera Gustavo Hinostroza Huamán Adler
Farroñay Antón Iván Llanos Tenorio Edgar Jhasler
Guerrero Jaramillo Sergio Daniel Quesquén Neciosup Víctor

5. SYPHILIS
IS
A SEXUALLY TRANSMITTED DISEASE
CAUSED BY
THE BACTERIUM TREPONEMA PALLIDIUM

6. It is called
VENEREAL SYPHILIS It is known as
CONGENITAL SYPHILIS

7. PAINLESS ULCERS
CHANCRES

9. and
AFTER ABOUT TWO YEARS
AN INFECTED MAN
may

10. MANY ORGANS MAY BE AFFECTED

21. Chancroid Syphilis
Painless ulcers
Can be very
painful
hard (indurated) edge
have a soft edge
can occur in the pharynx
as well as on the genitals

24. STAGE DIAGNOSE OPINION
PRIMARY Physical examination findings:
Ulcer is usually single, hardened (genital or non-genital)
painless testing positive by darkfield / PCR, or
highly suspected chancre may be one based on the clinic.
SECONDARY Physical examination findings:
• Rash (local or generalized) without explanation
• Rash on the palms or soles
• mucous patches (lesions on the tongue, buccal mucosa, lips)
• Condyloma lata (flat, wet, gray-whitish plaques)
• patchy Alopecia

27. Immediate examination
Lesion moist
Lesion moist

28. • All patients with genital ulcer is due to take tests for Syphilis and Herpes
Virus as they are two differential diagnoses and present the association.
• Provides a review of the injury and is performed Gram stain which will
show Gram negative coccobacilli.
• Cultivation of the base of the ulcer or node aspirates (60-80% sensitivity, i.e
detects growing from 60 to 80% of infected individuals
• You can also perform a biopsy of the lesions which is always presented
diagnostic.