QuiremSpheres are the next generation of microspheres for radioembolisation treatment of liver cancer. They offer superior targeting of tumors with higher dose rates for more effective killing of cancer cells. QuiremSpheres are uniquely visible with imaging, enabling personalized and real-time image-guided treatment with evaluation of treatment response. The company was spun off from the University Medical Center Utrecht and is preparing for product launch in early 2015 with a seasoned management team and growing clinical evidence base. Main start-up challenges include assembling the right team, securing support and partners, and attracting the right investors.