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AIM: What are the overall factors
       causing evolution?


                Warm-up:
Briefly describe 2 mechanisms that could
           account for speciation.
5 Agents of evolutionary change
5 Agents of evolutionary change
    Mutation
5 Agents of evolutionary change
    Mutation   Gene Flow
5 Agents of evolutionary change
    Mutation   Gene Flow   Non-random mating
5 Agents of evolutionary change
    Mutation                   Gene Flow   Non-random mating




               Genetic Drift
5 Agents of evolutionary change
    Mutation                   Gene Flow        Non-random mating




               Genetic Drift               Selection
1. Mutation & Variation
1. Mutation & Variation
1. Mutation & Variation
 § Mutation creates variation
1. Mutation & Variation
 § Mutation creates variation
   u   new mutations are constantly appearing
1. Mutation & Variation
 § Mutation creates variation
   u   new mutations are constantly appearing
 § Mutation changes DNA sequence
1. Mutation & Variation
 § Mutation creates variation
   u   new mutations are constantly appearing
 § Mutation changes DNA sequence
   u   changes amino acid sequence
1. Mutation & Variation
 § Mutation creates variation
   u   new mutations are constantly appearing
 § Mutation changes DNA sequence
   u   changes amino acid sequence
   u   changes protein
1. Mutation & Variation
 § Mutation creates variation
   u   new mutations are constantly appearing
 § Mutation changes DNA sequence
   u   changes amino acid sequence
   u   changes protein
   u   changes in protein may
       change phenotype &
       therefore change fitness
2. Gene Flow
2. Gene Flow
2. Gene Flow
 § Movement of individuals &
  alleles in & out of populations
2. Gene Flow
 § Movement of individuals &
  alleles in & out of populations
   u   seed & pollen distribution by
       wind & insect
2. Gene Flow
 § Movement of individuals &
  alleles in & out of populations
   u   seed & pollen distribution by
       wind & insect
   u   migration of animals
2. Gene Flow
 § Movement of individuals &
  alleles in & out of populations
   u   seed & pollen distribution by
       wind & insect
   u   migration of animals
       § sub-populations may have
         different allele frequencies
2. Gene Flow
 § Movement of individuals &
  alleles in & out of populations
   u   seed & pollen distribution by
       wind & insect
   u   migration of animals
       § sub-populations may have
         different allele frequencies
       § causes genetic mixing
         across regions
2. Gene Flow
 § Movement of individuals &
  alleles in & out of populations
   u   seed & pollen distribution by
       wind & insect
   u   migration of animals
       § sub-populations may have
         different allele frequencies
       § causes genetic mixing
         across regions
       § reduce differences
         between populations
Human evolution today
§ Gene flow in human
  populations is
  increasing today
  u   transferring alleles
      between populations
Human evolution today
§ Gene flow in human
  populations is
  increasing today
  u   transferring alleles
      between populations
Human evolution today
§ Gene flow in human
  populations is
  increasing today
  u   transferring alleles
      between populations




Are we moving towards a blended world?
3. Non-random mating
 § Sexual selection
3. Non-random mating
 § Sexual selection
4. Genetic drift
4. Genetic drift
4. Genetic drift
§ Effect of chance events
4. Genetic drift
§ Effect of chance events
  u   founder effect
4. Genetic drift
§ Effect of chance events
  u   founder effect
      § small group splinters off & starts a new colony
4. Genetic drift
§ Effect of chance events
  u   founder effect
      § small group splinters off & starts a new colony




                          er
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                     finc h
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                                        es
4. Genetic drift
§ Effect of chance events
  u   founder effect
      § small group splinters off & starts a new colony
  u   bottleneck




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                                        es
4. Genetic drift
§ Effect of chance events
  u   founder effect
      § small group splinters off & starts a new colony
  u   bottleneck
      § some factor (disaster) reduces population to
        small number & then population recovers &
        expands again

                          er
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                     finc h
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                                        es
4. Genetic drift
§ Effect of chance events
  u   founder effect
      § small group splinters off & starts a new colony
  u   bottleneck
      § some factor (disaster) reduces population to
        small number & then population recovers &
        expands again

                          er
                    Warbl
                     finc h
                               Gr
               s
               he




                               ou
           inc




                                  n d
          ef




                                    fin
           e




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        Tr




                                        es
Founder effect
Founder effect
 § When a new population is started
   by only a few individuals
   u   some rare alleles may be at high
       frequency; others may
       be missing
   u   skew the gene pool of
       new population
       § human populations that
         started from small group
         of colonists
       § example:
         colonization of New World
Distribution of blood types
 § Distribution of the O type blood allele in native
   populations of the world reflects original settlement
Distribution of blood types
 § Distribution of the O type blood allele in native
   populations of the world reflects original settlement
Distribution of blood types
 § Distribution of the O type blood allele in native
   populations of the world reflects original settlement
Distribution of blood types
 § Distribution of the B type blood allele in native
   populations of the world reflects original migration
Distribution of blood types
 § Distribution of the B type blood allele in native
   populations of the world reflects original migration
Distribution of blood types
 § Distribution of the B type blood allele in native
   populations of the world reflects original migration
Distribution of blood types
 § Distribution of the B type blood allele in native
   populations of the world reflects original migration
Bottleneck effect
Bottleneck effect
§ When large population is drastically
 reduced by a disaster
Bottleneck effect
§ When large population is drastically
 reduced by a disaster
  u   famine, natural disaster, loss of habitat…
Bottleneck effect
§ When large population is drastically
 reduced by a disaster
  u   famine, natural disaster, loss of habitat…
  u   loss of variation by chance event
Bottleneck effect
§ When large population is drastically
 reduced by a disaster
  u   famine, natural disaster, loss of habitat…
  u   loss of variation by chance event
      § alleles lost from gene pool
Bottleneck effect
§ When large population is drastically
 reduced by a disaster
  u   famine, natural disaster, loss of habitat…
  u   loss of variation by chance event
      § alleles lost from gene pool
         w not due to fitness
Bottleneck effect
§ When large population is drastically
 reduced by a disaster
  u   famine, natural disaster, loss of habitat…
  u   loss of variation by chance event
      § alleles lost from gene pool
         w not due to fitness
      § narrows the gene pool
Cheetahs
Cheetahs
§ All cheetahs share a small number of alleles
Cheetahs
§ All cheetahs share a small number of alleles
  u   less than 1% diversity
Cheetahs
§ All cheetahs share a small number of alleles
  u   less than 1% diversity
  u   as if all cheetahs are
      identical twins
Cheetahs
§ All cheetahs share a small number of alleles
  u   less than 1% diversity
  u   as if all cheetahs are
      identical twins
§ 2 bottlenecks
Cheetahs
§ All cheetahs share a small number of alleles
  u   less than 1% diversity
  u   as if all cheetahs are
      identical twins
§ 2 bottlenecks
  u   10,000 years ago
Cheetahs
§ All cheetahs share a small number of alleles
  u   less than 1% diversity
  u   as if all cheetahs are
      identical twins
§ 2 bottlenecks
  u   10,000 years ago
      § Ice Age
Cheetahs
§ All cheetahs share a small number of alleles
  u   less than 1% diversity
  u   as if all cheetahs are
      identical twins
§ 2 bottlenecks
  u   10,000 years ago
      § Ice Age
  u   last 100 years
Cheetahs
§ All cheetahs share a small number of alleles
  u   less than 1% diversity
  u   as if all cheetahs are
      identical twins
§ 2 bottlenecks
  u   10,000 years ago
      § Ice Age
  u   last 100 years
      § poaching & loss of habitat
Peregrine Falcon
Conservation issues




                              Golden Lion
                                  Tamarin
Peregrine Falcon
Conservation issues
§ Bottlenecking is an important
  concept in conservation
  biology of endangered
  species




                                          Golden Lion
                                              Tamarin
Peregrine Falcon
Conservation issues
§ Bottlenecking is an important
  concept in conservation
  biology of endangered
  species
   u   loss of alleles from gene pool




                                                Golden Lion
                                                    Tamarin
Peregrine Falcon
Conservation issues
§ Bottlenecking is an important
  concept in conservation
  biology of endangered
  species
   u   loss of alleles from gene pool
   u   reduces variation




                                                Golden Lion
                                                    Tamarin
Peregrine Falcon
  Conservation issues
  § Bottlenecking is an important
     concept in conservation
     biology of endangered
     species
     u   loss of alleles from gene pool
     u   reduces variation
     u   reduces adaptability



Breeding programs must
consciously outcross                              Golden Lion
                                                      Tamarin
5. Natural selection
5. Natural selection
§ Differential survival & reproduction due
  to changing environmental conditions
5. Natural selection
§ Differential survival & reproduction due
  to changing environmental conditions
     § climate change
5. Natural selection
§ Differential survival & reproduction due
  to changing environmental conditions
     § climate change
     § food source availability
5. Natural selection
§ Differential survival & reproduction due
  to changing environmental conditions
     § climate change
     § food source availability
     § predators, parasites, diseases
5. Natural selection
§ Differential survival & reproduction due
  to changing environmental conditions
     § climate change
     § food source availability
     § predators, parasites, diseases
     § toxins
5. Natural selection
§ Differential survival & reproduction due
  to changing environmental conditions
      § climate change
      § food source availability
      § predators, parasites, diseases
      § toxins
  u   combinations of alleles
      that provide “fitness”
      increase in the population
5. Natural selection
§ Differential survival & reproduction due
  to changing environmental conditions
      § climate change
      § food source availability
      § predators, parasites, diseases
      § toxins
  u   combinations of alleles
      that provide “fitness”
      increase in the population
      § adaptive evolutionary change

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1.6

  • 1. AIM: What are the overall factors causing evolution? Warm-up: Briefly describe 2 mechanisms that could account for speciation.
  • 2. 5 Agents of evolutionary change
  • 3. 5 Agents of evolutionary change Mutation
  • 4. 5 Agents of evolutionary change Mutation Gene Flow
  • 5. 5 Agents of evolutionary change Mutation Gene Flow Non-random mating
  • 6. 5 Agents of evolutionary change Mutation Gene Flow Non-random mating Genetic Drift
  • 7. 5 Agents of evolutionary change Mutation Gene Flow Non-random mating Genetic Drift Selection
  • 8. 1. Mutation & Variation
  • 9. 1. Mutation & Variation
  • 10. 1. Mutation & Variation § Mutation creates variation
  • 11. 1. Mutation & Variation § Mutation creates variation u new mutations are constantly appearing
  • 12. 1. Mutation & Variation § Mutation creates variation u new mutations are constantly appearing § Mutation changes DNA sequence
  • 13. 1. Mutation & Variation § Mutation creates variation u new mutations are constantly appearing § Mutation changes DNA sequence u changes amino acid sequence
  • 14. 1. Mutation & Variation § Mutation creates variation u new mutations are constantly appearing § Mutation changes DNA sequence u changes amino acid sequence u changes protein
  • 15. 1. Mutation & Variation § Mutation creates variation u new mutations are constantly appearing § Mutation changes DNA sequence u changes amino acid sequence u changes protein u changes in protein may change phenotype & therefore change fitness
  • 18. 2. Gene Flow § Movement of individuals & alleles in & out of populations
  • 19. 2. Gene Flow § Movement of individuals & alleles in & out of populations u seed & pollen distribution by wind & insect
  • 20. 2. Gene Flow § Movement of individuals & alleles in & out of populations u seed & pollen distribution by wind & insect u migration of animals
  • 21. 2. Gene Flow § Movement of individuals & alleles in & out of populations u seed & pollen distribution by wind & insect u migration of animals § sub-populations may have different allele frequencies
  • 22. 2. Gene Flow § Movement of individuals & alleles in & out of populations u seed & pollen distribution by wind & insect u migration of animals § sub-populations may have different allele frequencies § causes genetic mixing across regions
  • 23. 2. Gene Flow § Movement of individuals & alleles in & out of populations u seed & pollen distribution by wind & insect u migration of animals § sub-populations may have different allele frequencies § causes genetic mixing across regions § reduce differences between populations
  • 24. Human evolution today § Gene flow in human populations is increasing today u transferring alleles between populations
  • 25. Human evolution today § Gene flow in human populations is increasing today u transferring alleles between populations
  • 26. Human evolution today § Gene flow in human populations is increasing today u transferring alleles between populations Are we moving towards a blended world?
  • 27. 3. Non-random mating § Sexual selection
  • 28. 3. Non-random mating § Sexual selection
  • 31. 4. Genetic drift § Effect of chance events
  • 32. 4. Genetic drift § Effect of chance events u founder effect
  • 33. 4. Genetic drift § Effect of chance events u founder effect § small group splinters off & starts a new colony
  • 34. 4. Genetic drift § Effect of chance events u founder effect § small group splinters off & starts a new colony er Warbl finc h Gr s he ou inc n d ef fin e ch Tr es
  • 35. 4. Genetic drift § Effect of chance events u founder effect § small group splinters off & starts a new colony u bottleneck er Warbl finc h Gr s he ou inc n d ef fin e ch Tr es
  • 36. 4. Genetic drift § Effect of chance events u founder effect § small group splinters off & starts a new colony u bottleneck § some factor (disaster) reduces population to small number & then population recovers & expands again er Warbl finc h Gr s he ou inc n d ef fin e ch Tr es
  • 37. 4. Genetic drift § Effect of chance events u founder effect § small group splinters off & starts a new colony u bottleneck § some factor (disaster) reduces population to small number & then population recovers & expands again er Warbl finc h Gr s he ou inc n d ef fin e ch Tr es
  • 39. Founder effect § When a new population is started by only a few individuals u some rare alleles may be at high frequency; others may be missing u skew the gene pool of new population § human populations that started from small group of colonists § example: colonization of New World
  • 40. Distribution of blood types § Distribution of the O type blood allele in native populations of the world reflects original settlement
  • 41. Distribution of blood types § Distribution of the O type blood allele in native populations of the world reflects original settlement
  • 42. Distribution of blood types § Distribution of the O type blood allele in native populations of the world reflects original settlement
  • 43. Distribution of blood types § Distribution of the B type blood allele in native populations of the world reflects original migration
  • 44. Distribution of blood types § Distribution of the B type blood allele in native populations of the world reflects original migration
  • 45. Distribution of blood types § Distribution of the B type blood allele in native populations of the world reflects original migration
  • 46. Distribution of blood types § Distribution of the B type blood allele in native populations of the world reflects original migration
  • 48. Bottleneck effect § When large population is drastically reduced by a disaster
  • 49. Bottleneck effect § When large population is drastically reduced by a disaster u famine, natural disaster, loss of habitat…
  • 50. Bottleneck effect § When large population is drastically reduced by a disaster u famine, natural disaster, loss of habitat… u loss of variation by chance event
  • 51. Bottleneck effect § When large population is drastically reduced by a disaster u famine, natural disaster, loss of habitat… u loss of variation by chance event § alleles lost from gene pool
  • 52. Bottleneck effect § When large population is drastically reduced by a disaster u famine, natural disaster, loss of habitat… u loss of variation by chance event § alleles lost from gene pool w not due to fitness
  • 53. Bottleneck effect § When large population is drastically reduced by a disaster u famine, natural disaster, loss of habitat… u loss of variation by chance event § alleles lost from gene pool w not due to fitness § narrows the gene pool
  • 55. Cheetahs § All cheetahs share a small number of alleles
  • 56. Cheetahs § All cheetahs share a small number of alleles u less than 1% diversity
  • 57. Cheetahs § All cheetahs share a small number of alleles u less than 1% diversity u as if all cheetahs are identical twins
  • 58. Cheetahs § All cheetahs share a small number of alleles u less than 1% diversity u as if all cheetahs are identical twins § 2 bottlenecks
  • 59. Cheetahs § All cheetahs share a small number of alleles u less than 1% diversity u as if all cheetahs are identical twins § 2 bottlenecks u 10,000 years ago
  • 60. Cheetahs § All cheetahs share a small number of alleles u less than 1% diversity u as if all cheetahs are identical twins § 2 bottlenecks u 10,000 years ago § Ice Age
  • 61. Cheetahs § All cheetahs share a small number of alleles u less than 1% diversity u as if all cheetahs are identical twins § 2 bottlenecks u 10,000 years ago § Ice Age u last 100 years
  • 62. Cheetahs § All cheetahs share a small number of alleles u less than 1% diversity u as if all cheetahs are identical twins § 2 bottlenecks u 10,000 years ago § Ice Age u last 100 years § poaching & loss of habitat
  • 64. Peregrine Falcon Conservation issues § Bottlenecking is an important concept in conservation biology of endangered species Golden Lion Tamarin
  • 65. Peregrine Falcon Conservation issues § Bottlenecking is an important concept in conservation biology of endangered species u loss of alleles from gene pool Golden Lion Tamarin
  • 66. Peregrine Falcon Conservation issues § Bottlenecking is an important concept in conservation biology of endangered species u loss of alleles from gene pool u reduces variation Golden Lion Tamarin
  • 67. Peregrine Falcon Conservation issues § Bottlenecking is an important concept in conservation biology of endangered species u loss of alleles from gene pool u reduces variation u reduces adaptability Breeding programs must consciously outcross Golden Lion Tamarin
  • 69. 5. Natural selection § Differential survival & reproduction due to changing environmental conditions
  • 70. 5. Natural selection § Differential survival & reproduction due to changing environmental conditions § climate change
  • 71. 5. Natural selection § Differential survival & reproduction due to changing environmental conditions § climate change § food source availability
  • 72. 5. Natural selection § Differential survival & reproduction due to changing environmental conditions § climate change § food source availability § predators, parasites, diseases
  • 73. 5. Natural selection § Differential survival & reproduction due to changing environmental conditions § climate change § food source availability § predators, parasites, diseases § toxins
  • 74. 5. Natural selection § Differential survival & reproduction due to changing environmental conditions § climate change § food source availability § predators, parasites, diseases § toxins u combinations of alleles that provide “fitness” increase in the population
  • 75. 5. Natural selection § Differential survival & reproduction due to changing environmental conditions § climate change § food source availability § predators, parasites, diseases § toxins u combinations of alleles that provide “fitness” increase in the population § adaptive evolutionary change