This editorial discusses the first year of the journal Molecular Cancer. It summarizes that in its first year, Molecular Cancer published 16 research papers after rejecting 32 submissions, with an average turnaround time of one month. It also discusses the journal's commitment to open access publishing and rapid peer review. The editorial highlights some of the most accessed papers from the first year and says readership and citation will prove the scientific merit of published papers. It concludes by stating the journal will continue publishing manuscripts in all areas of cancer science.