This document provides 13 steps to help recover from cancer. It discusses questioning treatment plans, checking all treatment options including alternative therapies, getting second opinions, hiring expert cancer coaches, preparing physically and mentally before treatment, starving cancer cells by reducing sugar and meat intake, detoxing and alkalizing the body, assembling a support team, being your own advocate, compiling a personal health record, managing physical and emotional pain and stress, and verifying that treatment is working through various laboratory tests.
SHARE Presentation: Integrative Medicine and Cancer with Dr. Heather Greenleebkling
Oncology doctors are considering new ways in addition to conventional care to improve cancer outcomes. Examples of integrative medicine include acupuncture, mind-body approaches, and botanicals. Dr. Heather Greenlee of Columbia University Mailman School of Public Health will discuss new guidelines developed within the Society for Integrative Oncology.
Developing a cancer survivorship research agenda - Prof Patricia GanzIrish Cancer Society
A presentation given at the Irish Cancer Society's Survivorship Research Day at the Aviva Stadium, Dublin on Thursday, September 20th, 2013.
Developing a cancer survivorship research agenda: challenges & opportunities - Prof Patricia Ganz, UCLA Fielding School of Public Health
Jefferson University Hospitals' April 2013 Cancer Survivorship Conference Pre...jeffersonhospital
At Jefferson University Hospitals' Cancer Survivorship Conference on April 12, 2013, Mary McCabe of Memorial Sloan-Kettering Cancer Center gave the keynote address. Jefferson's new Survivorship platform includes biannual conferences featuring keynote speakers and several breakout sessions to give cancer patients, survivors and caregivers a better understanding of survivorship and what comes next after a cancer diagnosis. This is a free event open to all cancer patients and survivors. Learn more: http://www.jeffersonhospital.org/departments-and-services/kimmel-cancer-center/cancer-survivorship-program
SHARE Presentation: Integrative Medicine and Cancer with Dr. Heather Greenleebkling
Oncology doctors are considering new ways in addition to conventional care to improve cancer outcomes. Examples of integrative medicine include acupuncture, mind-body approaches, and botanicals. Dr. Heather Greenlee of Columbia University Mailman School of Public Health will discuss new guidelines developed within the Society for Integrative Oncology.
Developing a cancer survivorship research agenda - Prof Patricia GanzIrish Cancer Society
A presentation given at the Irish Cancer Society's Survivorship Research Day at the Aviva Stadium, Dublin on Thursday, September 20th, 2013.
Developing a cancer survivorship research agenda: challenges & opportunities - Prof Patricia Ganz, UCLA Fielding School of Public Health
Jefferson University Hospitals' April 2013 Cancer Survivorship Conference Pre...jeffersonhospital
At Jefferson University Hospitals' Cancer Survivorship Conference on April 12, 2013, Mary McCabe of Memorial Sloan-Kettering Cancer Center gave the keynote address. Jefferson's new Survivorship platform includes biannual conferences featuring keynote speakers and several breakout sessions to give cancer patients, survivors and caregivers a better understanding of survivorship and what comes next after a cancer diagnosis. This is a free event open to all cancer patients and survivors. Learn more: http://www.jeffersonhospital.org/departments-and-services/kimmel-cancer-center/cancer-survivorship-program
SHARE Presentation: Palliative Care for Womenbkling
Dr. Michael Pearl discusses supportive palliative care for women with cancer, how it differs from hospice care, and the New York Palliative Care Information Act. Dr. Michael Pearl is Professor and Director of the Division of Gynecologic Oncology in the Department of Obstetrics, Gynecology and Reproductive Medicine at Stony Brook University Hospital.
Sharon L. Bober, Ph.D.
Director, Sexual Health Program
Dana-Farber Cancer Institute
Assistant Professor, Dept. of Psychiatry
Harvard Medical School
Boston, MA
Difficult Conversations: Bridging the Communication Gap with Your OncologistMelissa Sakow
Lidia Schapira, MD, Director of the Cancer Survivorship Program at Stanford University, shares her expertise to help you get the most out of your communication with your oncologist. Learn strategies to optimize your meetings with your health care team.
Ayurvedic medicine is a system of traditional Hindu medicine native to the Indian subcontinent. Contemporary practices derived from Ayurvedic traditions are a type of alternative medicine. Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues.People with cancer often use touch therapies such as massage and aromatherapy. Many people say these therapies help them to cope better with cancer and its treatment. Research is looking into whether some herbs or plant treatments used in Ayurvedic medicine could help to prevent or treat cancer.
We will cover the topic of Palliative Care – specialized medical care for people with serious illnesses. It focuses on providing patients with relief from the symptoms and stress of a serious illness. The goal is to improve quality of life for both the patient and the family.
Presented by Dr. Jean S. Kutner, MD, MSPH a tenured Professor of Medicine in the Divisions of General Internal Medicine (GIM), Geriatric Medicine, and Health Care Policy and Research at the University of Colorado School of Medicine (UC SOM)
2014 Cancer Survivorship Conference at Jefferson University Hospitalsjeffersonhospital
Jefferson's Cancer Survivorship Program will help you understand what it means to be a cancer survivor and what to expect from your cancer diagnosis, treatment and follow-up care. This Program is for current patients, cancer survivors and loved ones who have lived with a cancer diagnosis or have undergone cancer treatment at Jefferson.
Jeffrey A. Meyerhardt, MD, MPH
Associate Professor of Medicine, Harvard Medical School Active Medical Staff, Medical Oncology, Dana-Farber Cancer Institute - speaker for Tuesday Call-on Congress 2012
Hospice care and palliative care: Is there a difference between the two, and if so, what?
Many people still think that palliative care means hospice care. But today, hospice is only a small part of palliative care.
The goal of palliative care is to prevent or treat the symptoms and side effects of a disease; and it should be part of the picture from the first day a serious illness is diagnosed.
Dr. Jim Meadows, Director of Hospice and Palliative Care at Tennessee Oncology, will discuss this important topic. How does a family and a health care team best work together to guide a patient through a terminal illness? How does everyone continue to support quality, patient-centered, end-of-life care?
Don't miss our upcoming webinars. Subscribe today!
In part 2 of our empowerment series: Oncologist Rob Rutledge provides an overview of cancer, its treatment and how to get the best medical care in this empowering presentation. He follows with practical advice about diverse complementary treatments and techniques, and how to integrate them into your healing journey.
View the video:
https://youtu.be/8IM-okz7PSY
To learn more about CCSN, visit us at survivornet.ca
Follow CCSN on social media:
Twitter - https://twitter.com/survivornetca
Facebook - https://www.facebook.com/CanadianSurvivorNet
Instagram: https://www.instagram.com/survivornet_ca/
Pinterest - https://www.pinterest.com/survivornetwork
Is hating your work ruining your life? It seems like there might be an epidemic of people who dread going to work, hate what they do, and are desperate to make a change.
You don’t have to be unhappy at work, even when there are things that are out of your control. It’s those things that are in your control that can make you happier at work.
SHARE Presentation: Palliative Care for Womenbkling
Dr. Michael Pearl discusses supportive palliative care for women with cancer, how it differs from hospice care, and the New York Palliative Care Information Act. Dr. Michael Pearl is Professor and Director of the Division of Gynecologic Oncology in the Department of Obstetrics, Gynecology and Reproductive Medicine at Stony Brook University Hospital.
Sharon L. Bober, Ph.D.
Director, Sexual Health Program
Dana-Farber Cancer Institute
Assistant Professor, Dept. of Psychiatry
Harvard Medical School
Boston, MA
Difficult Conversations: Bridging the Communication Gap with Your OncologistMelissa Sakow
Lidia Schapira, MD, Director of the Cancer Survivorship Program at Stanford University, shares her expertise to help you get the most out of your communication with your oncologist. Learn strategies to optimize your meetings with your health care team.
Ayurvedic medicine is a system of traditional Hindu medicine native to the Indian subcontinent. Contemporary practices derived from Ayurvedic traditions are a type of alternative medicine. Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues.People with cancer often use touch therapies such as massage and aromatherapy. Many people say these therapies help them to cope better with cancer and its treatment. Research is looking into whether some herbs or plant treatments used in Ayurvedic medicine could help to prevent or treat cancer.
We will cover the topic of Palliative Care – specialized medical care for people with serious illnesses. It focuses on providing patients with relief from the symptoms and stress of a serious illness. The goal is to improve quality of life for both the patient and the family.
Presented by Dr. Jean S. Kutner, MD, MSPH a tenured Professor of Medicine in the Divisions of General Internal Medicine (GIM), Geriatric Medicine, and Health Care Policy and Research at the University of Colorado School of Medicine (UC SOM)
2014 Cancer Survivorship Conference at Jefferson University Hospitalsjeffersonhospital
Jefferson's Cancer Survivorship Program will help you understand what it means to be a cancer survivor and what to expect from your cancer diagnosis, treatment and follow-up care. This Program is for current patients, cancer survivors and loved ones who have lived with a cancer diagnosis or have undergone cancer treatment at Jefferson.
Jeffrey A. Meyerhardt, MD, MPH
Associate Professor of Medicine, Harvard Medical School Active Medical Staff, Medical Oncology, Dana-Farber Cancer Institute - speaker for Tuesday Call-on Congress 2012
Hospice care and palliative care: Is there a difference between the two, and if so, what?
Many people still think that palliative care means hospice care. But today, hospice is only a small part of palliative care.
The goal of palliative care is to prevent or treat the symptoms and side effects of a disease; and it should be part of the picture from the first day a serious illness is diagnosed.
Dr. Jim Meadows, Director of Hospice and Palliative Care at Tennessee Oncology, will discuss this important topic. How does a family and a health care team best work together to guide a patient through a terminal illness? How does everyone continue to support quality, patient-centered, end-of-life care?
Don't miss our upcoming webinars. Subscribe today!
In part 2 of our empowerment series: Oncologist Rob Rutledge provides an overview of cancer, its treatment and how to get the best medical care in this empowering presentation. He follows with practical advice about diverse complementary treatments and techniques, and how to integrate them into your healing journey.
View the video:
https://youtu.be/8IM-okz7PSY
To learn more about CCSN, visit us at survivornet.ca
Follow CCSN on social media:
Twitter - https://twitter.com/survivornetca
Facebook - https://www.facebook.com/CanadianSurvivorNet
Instagram: https://www.instagram.com/survivornet_ca/
Pinterest - https://www.pinterest.com/survivornetwork
Is hating your work ruining your life? It seems like there might be an epidemic of people who dread going to work, hate what they do, and are desperate to make a change.
You don’t have to be unhappy at work, even when there are things that are out of your control. It’s those things that are in your control that can make you happier at work.
Este material se comparte con el animo que compartir material de investigacion. del profesor Rene. y el Doctor Sergio Tobon, para mayor informacion consultarsu pagina web.
CANCER IS THE WORLD’S LEADING CAUSE OF DEATH, BUT ABOUT 1 IN 3 CASES CAN BE PREVENTED, ACCORDING TO THE WORLD HEALTH ORGANIZATION.
THERE’S NO MAGIC PILL TO KEEP YOU FROM GETTING CANCER, BUT YOU Can DO SOME THINGS TO IMPROVE YOUR ODDS
AN EYE OPENER
I am not telling you that you have to do this, I am nearly asking you to have an open mind and research the information I am providing.
Last week my husband and I had the opportunity to be part of the Annual Cancer Convention/Alternative therapies. We heard well-known medical doctors, clinical researchers, nutritionists and authors speak on prevention and control of cancer along with other diseases through nutrition, tests and non-toxic therapies.
For nearly seven years of research, since I was diagnosed with breast cancer stage 2 and I have always believed in non-toxic treatments. My husband and I both were struck with this disease and neither of us had surgery, chemo and radiation. To this day we are striving to educate others in the cause of managing a healthier lifestyle, for this is the first step to a cleaner life. Through opening others minds to what is out there, for them to see that you do not need chemicals and toxins to heal this disease.
By going to the convention, it just broadens our knowledge in just what is out there as far as products, assistance, and treatments. Here are some slides and pictures from this amazing three days of listening to speakers, talking to vendors and patients from all over.
REMEMBER THERE ARE NO MISTAKES JUST LESSONS.
TRUST YOUR SELF AND LOVE YOUR SELF.
WITH THIS ANYTHING IS POSSIBLE.
KNOWLEDGE IS POWER
Cancer for the survivors of this great disease, the support and early detection is key to managing this disease which has taken both the rich and the poor, the famous and the unprivileged on the same scale.
The outlook for cancer treatment options is a promising one. Researchers and physicians are discovering new ways to identify the best care for patients through targeted treatments. With the large number of cancer types, a treatment plan that works well for one person may not be the best plan for another. Through collaboration, rapidly evolving technology, and research in genetics and the molecular profiling of tumors, researchers and physicians have made astounding strides in the development of personalized cancer care.
Stage 4 Breast Cancer | Breast Cancer Treatment in India | Oncology IndiaOncology India
Breast Cancer Treatment in India | Oncology India have a specialized Top Breast Cancer Specialist in Bangalore to cure breast cancer related issues.
To Know More,
Click Here,
http://www.oncologyinternational.com/
The psychological impact of living with and beyond cancer - reportAlex King
Earlier diagnosis and advances in treatment mean that more people are living with and beyond cancer,1 with approximately half of those diagnosed today living for ten years or more.2 Alongside positive clinical outcomes is the need to identify the key psychological challenges faced by individuals experiencing longterm cancer survival, and whether current provision of psychological support and services meet the needs of this relatively new group of patients. It is important to note that the psychological challenges faced during long-term survivorship are often not independent of those experienced at other points in a patient’s journey, including diagnosis, during or at completion of treatment, remission or at no evidence of disease (NED). As such, a broader view is necessary to ensure that psychological challenges faced in long-term survivorship are not addressed in isolation and individual impact is acknowledged.
Many European countries include referral pathways to psychological support in cancer care guidelines however, this is not always the case in the UK. For example, lung cancer guidelines do not include psychological assessment, referral pathways to psychological support or mention psychological burden.3 Existing guidance relating to the supportive and palliative care for adults with cancer was published by the National Institute for Health and Care Excellence (NICE) in 2004.4 Since then, the cancer treatment landscape has seen significant advances with earlier diagnosis and improved survival rates alongside changes within the wider environment including the advent of social media and other digital resources.
The ‘Psychological Support for Patients Living with Cancer - Patient Workshop’ aimed to identify the uniting, unmet psychological needs of people living with and beyond cancer. The workshop found the following key themes: • Prioritising quality of life (QoL) • Challenge of re-introduction to the community following treatment • The impact of cancer on families and carers
When addressing the provision of psychological support and ways in which current services could be improved, the following areas were discussed: • Integrating psychological support into the treatment pathway • Improving timing and communication • Securing timely support • Acknowledging differences • Getting support for families and carers
The wider environment, existing initiatives and the resulting workshop learnings will help inform MSD’s wider understanding of this topic and help to shape future planning regarding MSD’s contribution to support the psychological well-being of patients living with and beyond cancer.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
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We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdf
13 steps to aid recovery from cancer
1. Thirteen Steps to Help You Recover from Cancer
1. Question Everything You Are Told
Whether you beat cancer or die from it depends a lot on the Treatment Plan you follow.
When your medical team proposes a Treatment Plan, you absolutely need to ask:
How effective is this treatment for my type of cancer?
Will you show me a few studies that will verify this treatment will prolong my life, when
directly compared to no treatment at all?
Will you get permission from a few of the patients you have treated with this method so
that I can speak to them?
Will this treatment cause secondary cancers?
What is the chance that the cancer will come back after treatment?
Could the side-effects cause serious pain, damage to vital organs or death?
What tests could help determine the treatment most likely to work for me?
(if you opt for chemo, ask about Chemo-sensitivity testing to determine the best drugs)
See a full list of questions at cancerireland.ie
2. Thirteen Steps to Help You Recover from Cancer
2. Check out all your treatment options
If you are referred to a mainstream oncology department in your local hospital, you will be
offered Conventional Treatment. The most commonly used Conventional Treatments are
Surgery, Chemotherapy and Radiotherapy. You may be offered a combination of these
treatments depending on your cancer type and a whole range of other considerations.
Regrettably, you will not be offered (or even told about) Alternative Cancer Treatments.
These are natural or other treatments that are being used successfully around the world and
include High Intensity Focused Ultrasound (HIFU), Gerson therapy, Budwig Protocol, Iscador
and others.
Many cancer clinics now successfully use a mix of conventional and alternative treatments for
better outcomes. This is known as Integrative Medicine.
There are also numerous Complementary therapies. These are used to augment your
primary treatment(s), reduce pain and stress, boost your immune system etc.
See a full list of treatments at cancerireland.ie
3. Thirteen Steps to Help You Recover from Cancer
3. Get a Second Opinion
Doctors can have their own opinions and thoughts about how to practice medicine. They can
have different ideas about how to diagnose and treat conditions or diseases. Some doctors
take a more conservative, or traditional, approach to treating their patients.
Not every doctor can be skilled in using all the latest technology. Getting a second opinion
from a different doctor might give you a fresh perspective and new information. It could
provide you with new options for treating your condition. Then you can make more informed
choices.
Ask your doctor for a recommendation.
Ask someone you trust for a recommendation.
Check with your health insurance provider.
Ask to have medical records sent to the second doctor.
Learn as much as you can about your condition.
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4. Thirteen Steps to Help You Recover from Cancer
4. Get Expert Personal Cancer Coaching
You can get expert advice from experienced Cancer Coaches to help you decide which
treatment gives you the best possible chance of returning to full health. It doesn’t cost much
and you can speak directly to the coaches by telephone and online.
Two well-known successful coaches are Ralph Moss and Burton Goldberg.
Burton Goldberg has traveled the world in search of the top therapies and treatments
available from the fields of alternative medicine, natural healthcare, integrative medicine and
conventional medicine. He is available for healthcare consultations by telephone to help you
and your family choose the top healthcare treatments available for all types of cancer.
Ralph W. Moss, PhD, offers phone consultations to help patients individualize their cancer
treatment. In pursuing this goal, he not only studies the relevant scientific literature, but
frequently travels the world in search of doctors, clinics and hospitals offering new and
effective approaches. He also investigates new food supplements and other purported
treatments. Dr. Moss maintains an attitude of “friendly skepticism.” While he is open to
credible new treatment options, both conventional and alternative, he demands proof of
both their safety and effectiveness. He will not be swayed by anything less than rigorous
scientific evidence.
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5. Thirteen Steps to Help You Recover from Cancer
5. Check out “Prehabilitation”
Time between diagnosis and treatment provides a ‘window of opportunity’ to optimize
health. For patients with cancer, “prehabilitation”— interventions given between the time of
diagnosis and the start of treatment—has the potential to reduce complications from
treatments and improve physical and mental health outcomes, according to a report in the
American Journal of Physical Medicine & Rehabilitation.
Some studies have shown that prehabilitation interventions, individually or in combination,
can increase the range of treatment options, lower complication rates, and improve physical
and mental health outcomes. Benefits include a reduced risk of hospital readmission and
lower health care costs.
Studies have begun to show that physical and psychological prehabilitation interventions can
reduce treatment-related complications, decrease length of hospital stay and/or
readmissions, increase available treatment options for patients who would not otherwise be
candidates, and quickly facilitate return of patients to the highest level of function possible.
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6. Thirteen Steps to Help You Recover from Cancer
6. Starve Your Cancer
A number of medical scientists and alternative practitioners know that the most logical,
effective and safe way to treat cancer is to cut off the supply of food to tumors and cancer
cells, starving them with a lack of glucose (sugar).
Cancer cells derive their energy from an process known as glycolysis. Glycolysis requires
glucose; without it most cancer cells simply cannot survive.
Like sugar, meat feeds cancer cells.
Oncologists generally agree that the actual cause of death in cancer patients is cachexia, a
condition of severe weight loss and wasting associated with protein mal-absorption.
Meat, especially red meat, being the most readily assimilable protein, becomes a banquet for
cancer cells.
Emphasizing the use of plant sources of vegetable protein such as legumes and beans that
contain cancer-fighting compounds should be a prominent part of an anti-cancer diet.
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7. Thirteen Steps to Help You Recover from Cancer
7. Detox and Alkalize Your Body
Detoxification is a very important factor in dealing with disease in general but especially cancer.
Nowadays, every person has a body overloaded with toxins. The WORSE toxins are those you put on your
body, including cosmetics and shampoo.
There are a number of ways to detox, including:
Induced sweating (physical exercise)
Alpha lipoic acid (ALA) is the most biologically active form of lipoic acid and is the form that the body
produces naturally. ALA is a powerful antioxidant and mercury chelator.
Magnesium is a crucial factor in the natural self-cleansing and detoxification response of the body.
Other ways to detox include Vitamin C, Raw Food Diet, Yoga.
Alkalization
In the 1930’s, an interesting natural cancer treatment was proposed as a simple, effective answer to
cancer – almost any cancer. This treatment approach is called alkaline therapy or pH therapy.
Ideally, this approach begins with an alkaline diet. There is general agreement amongst natural healers
and medical professionals alike, that changing a cancer patient’s diet is extremely helpful when someone
is confronted with a cancer diagnosis
The second step is to use some nutritional mechanism to move the internal cancer cell pH from the
optimal mitosis range of pH 6.5 to 7.5, to above 8, which shortens the life of the cancer cell.
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8. Thirteen Steps to Help You Recover from Cancer
8. Recruit Your Support Team
Even though your needs are greater when you have cancer, it can be hard to ask for help to meet
those needs. To get the help you need, think about turning to:
→ family and friends can keep you company, help with meals, errands, go with you to doctor’s
visits or treatment sessions etc
→ others who also have cancer can talk with you about what to expect. give you hope for the
future, tell you how they cope with cancer and live a normal life etc
→ people in support groups can help each other feel better, more hopeful and not so alone and
learn about what’s new in cancer treatment
→ people from your spiritual or religious community can help with your struggle to understand
why you have cancer or wonder about life’s purpose and how cancer fits in the “fabric of life”
→ health care providers: Doctors , Nurses, Pharmacists, Social Workers, Psychologists can all help
you with physical or mental pain or anxiety.
→ caregivers are the people who help with your daily tasks such as bathing, getting dressed, or
eating. Caregivers are often family members or close friends.
People feel good when they help others.
No one needs to face cancer alone. When people with cancer seek and receive help from others,
they often find it easier to cope.
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9. Thirteen Steps to Help You Recover from Cancer
9. Be Your Own Advocate
Even though your needs are greater when you have cancer, it can be hard to ask for help to meet
those needs. To get the help you need, remember:
→ family and friends can keep you company, help with meals, errands, go with you to doctor’s
visits or treatment sessions etc
→ others who also have cancer can talk with you about what to expect. give you hope for the
future, tell you how they cope with cancer and live a normal life etc
→ people in support groups can help each other feel better, more hopeful and not so alone and
learn about what’s new in cancer treatment
→ people from your spiritual or religious community can help with your struggle to understand
why you have cancer or wonder about life’s purpose and how cancer fits in the “fabric of life”
→ health care providers: Doctors , Nurses, Pharmacists, Social Workers, Psychologists can all help
you with physical or mental pain or anxiety.
→ caregivers are the people who help with your daily tasks such as bathing, getting dressed, or
eating. Caregivers are often family members or close friends.
People feel good when they help others.
No one needs to face cancer alone. When people with cancer seek and receive help from others,
they often find it easier to cope.
See more at cancerireland.ie
10. Thirteen Steps to Help You Recover from Cancer
10. Compile a Personal Health Record
The Personal Health Record is a tool that you can use to collect, track and share past and current
information about your health and can give your medical care providers more insight into your personal
health story.
You are ultimately responsible for making decisions about your health. A Personal Health Record can help
you accomplish that.
Medical records and your personal health record are not the same thing.
Medical records contain information about your health compiled and maintained by each of your
healthcare providers. A Personal Health Record is information about your health compiled and
maintained by you.
There are several reasons to keep a personal medical record, including:
• Each facility or doctor involved in your care has a separate medical record for you. A personal medical
record combines these separate files into a single, more complete medical record.
• A personal medical record is always available when you need it. This is especially important if you go
to a new doctor or facility or if a record is lost or destroyed.
• A complete and accurate medical record gives new doctors the information they need to provide you
with the best possible care, including follow-up care and management of any side effects.
• Having your medical records at home gives you private time to read and understand them, which may
help you feel more in control of your health care.
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11. Thirteen Steps to Help You Recover from Cancer
11. Manage Physical Pain
Cancer or treatment for cancer may cause you to feel pain.
Tumors, surgery, chemotherapy, or radiation therapy may cause you pain. Patients with advanced cancer
have more severe pain, and many cancer survivors have pain that continues after cancer treatment ends.
Pain control can improve your quality of life.
Pain can be controlled in most patients with cancer. Although cancer pain cannot always be relieved
completely, there are ways to lessen pain in most patients. Pain control can improve your quality of life all
through your cancer treatment and after it ends.
Pain can be managed before, during, and after diagnostic and treatment procedures.
Many diagnostic and treatment procedures are painful. It helps to start pain control before the procedure
begins. Some drugs may be used to help you feel calm or fall asleep. Treatments such as imagery or
relaxation can also help control pain and anxiety related to treatment. Knowing what will happen during
the procedure and having a relative or friend stay with you may also help lower anxiety.
Pain can be treated in a number of ways, including:
• Drugs
• Radiation
• Nerve Blocks
• Physical treatments, such as heat, cold, and exercise
• Integrative treatments include massage therapy, acupuncture, and music.
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12. Thirteen Steps to Help You Recover from Cancer
12. Manage Anxiety and Stress
Anxiety and distress can affect the quality of life of patients with cancer and their families.
Patients living with cancer feel many different emotions, including anxiety and distress.
Anxiety is fear, dread, and uneasiness caused by stress.
Distress is emotional, mental, social, or spiritual suffering. Patients who are distressed may have a range
of feelings from vulnerability and sadness to depression, anxiety, panic, and isolation.
Anxiety and distress may affect a patient’s ability to cope with a cancer diagnosis or treatment. It may
cause patients to miss check-ups or delay treatment. Anxiety may increase pain, affect sleep, and cause
nausea and vomiting. Even mild anxiety can affect the quality of life for cancer patients and their families
and may need to be treated.
Treatment can include the following:
• Individual (one-to-one) counselling.
• Group therapy.
• Self-help groups.
• Hypnosis.
• Meditation.
• Relaxation training.
• Guided imagery.
• Biofeedback.
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13. Thirteen Steps to Help You Recover from Cancer
13. Verify Your Treatment Is Working
There are a number of laboratory tests available to check whether your treatment is working,
including:
CellSearch ®
The test identifies and counts the number of circulating tumor cells, down to 1 cell, and from an ordinary
7.5 ml blood sample. The cut off limit is 5, so if the patient has less than 5 CTCs the prognosis is far better
than if the number is above.
With the CTC test it is possible, after as early as 3 weeks, to see if a given treatment works. If not, it can
be stopped immediately and replaced by another type of treatment. This saves valuable time by avoiding
unnecessary treatment often associated with many side effects, and the CTC test is capable, much better
than previously, of predicting a specific prognosis.
ONCOTRACE
This test will report the number of Circulating Tumor Cells and any positive Circulating Cancer Stem Cells,
and the immunophenotype of these cells.
Other Tests:
The AMAS Test
The CA Profile
HCG Urine Immunoassay
Maintrac
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