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#Closingthegap
The Gradual Rise
of Women in
STEM Fields
New Horizons
Top Tech Trends
Shaping the Biotech
Industry
LEE ANN
KIMAK
Committed to Saving Lives through Exemplary Leadership
Most
Leaders in
for 2021
Admirable
Women
Biotech
0
NOVEMBER
ISSUE 04
2021
do not know what I may appear to the world, but to
Imyself, I seem to have been only like a boy playing on
the sea-shore and diverting myself in now and then
finding a smoother pebble or a prettier shell than ordinary,
whilst the great ocean of truth lay all undiscovered before
me.”
In this quote, Sir Isaac Newton believes that even though
our knowledge of the universe has expanded, it still stands
on the shore of the 'Great Ocean of Truth'. We are yet to
uncover the tiniest part of the wonders the universe holds.
But more importantly, there seems to be a strong desire in
humans to constantly expand this body of knowledge
because of the historical scientific wonders achieved so far.
From cloning of 'Dolly the Sleep' to 'Resurrection of
Species,' biotechnology has made it possible to discover
great marvels of science to be specific.
One such wonder was the discovery of mobile genetic
elements done by Dr Barbara McClintock in the year 1951.
Her research on plant breeding and genetic engineering
made her win the noble prize in Physiology, in 1983.
That's around three decades later!
Well, why do you think so?
Dr McClintock's work was 'ignored' for many years by her
peers in the scientific community. In the face of such
resistance, she stopped trying to convince people about her
discoveries but never stopped pursuing her theories.
Until a decade after her discovery, the scientific community
began to come up with the same conclusions and validated
her findings by giving her the credits that were long due.
She was a woman who changed science.
Likewise, multiple women are fighting against the odds and
making a big difference in the biotech industry. They have
ensured that the momentum doesn't die out. Women have
worked with passion, zeal, and an innovative approach.
As this awareness is growing, the biotech industry is taking
strides to encourage and represent women within the
industry.
In this edition, 10 Most Admirable Women Leaders in
Biotech for 2021, Insights Care has enlisted women who
have significantly impacted the biotech industry. By
highlighting this, I believe it is important to note that
women are not just demanding space in the industry
anymore. They are taking it.
We're proud to present these 10 women who inspire, lead,
and rebuild the Biotech industry. To know more about them,
kindly scroll through.
Also, don't forget to go through the articles written by our
in-house editorial team and a piece of CXO advice.
Dive in to have a happy read!
-Shrutika Khedekar
Whenever Suppressed,
'She' Rose!
“
e.
s and
ave
ve
.
aking
in
ho
ead,
them,
our
dekar
Editor’s Note
C
O
N
T
E
N
T
S Articles
#Closingthegap
The Gradual Rise of
Women in STEM Fields
New Horizons
Top Tech Trends Shaping
the Biotech Industry
24 38
Mindfully Driving the
Revolu on in Women's
Healthcare
Chia Chia Sun
An Ardent Advocate of
Digital Transforma on
of the Healthcare Industry
Maree Beare
An Ardent Advocate
of AI-driven Drug
Discovery
Noor Shaker
20
16
34
28
Natalie Bartlett
Chauffeur of Modern Change
in the Biotech Industry
CXO
08
Top 5 trends
in Radiology and
Imaging 44
Lee Ann Kimak
Commi ed to Saving Lives through
Exemplary Leadership
Cover Story
Co-designer Paul Belin
Art & Picture Editor Mrunalinee Deshmukh
Art & Design Head
Editor-in-Chief Sumita Sarkar
Managing Editor Abhishaj Sajeev
Senior Editor Anish Miller
Visualiser David King
Rohil Shinganapurkar
Circulation Manager Tanaji
Research Analyst Eric Smith
Sarah Wilson, John Smith, Alex Vincent
Business Development Executives
Amy Jones
Business Development Manager
Sales Executives Kelli, Bill, Anna
SME-SMO Executives Atul, Gemson
Digital Marketing Manager Alina Sege
Technical Consultants David, Robert
Technical Head Jacob Smile
Marketing Manager John Smith
Assistant Technical Head Pratiksha Patil
Assistant Digital Marketing Manager Amol Wadekar
Copyright © 2021 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or
transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights success.
Reprint rights remain solely with Insights Success Media and Technology Pvt. Ltd. Insights Care is powered by Insights Success Media and Technology Pvt. Ltd.
November, 2021
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Corporate Offices:
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td.
Description
Featuring
Bloody Good Period is now a charity, with a vision to
achieve menstrual equity - where the simple fact of bleeding
doesn't stop anyone from participating fully in society or
life.
Company Name
Bloody Good Period
Glamorous AI
Mesa Biotech
Gabby Edlin, CEO
Noor Shaker, Senior
Vice President,
and General Manager
Vipul Singh,
Director and COO
10 Most Admirable Women Leaders in Biotech for 2021
Vor Biopharma is a cell therapy company that combines a
novel patient engineering approach with targeted therapies
to provide a solution for patients suffering from
hematological malignancies.
Vor Biopharma
Amy Mendel,
Chief Legal Officer
Korro Bio’s team of experts is working to overcome the
challenges that have limited existing gene editing and gene
therapy approaches, and treat diseases that have previously
been unreachable by other methods.
Korro Bio, Inc.
Anna Barry, COO
Turning Point Therapeutics is a clinical-stage precision
oncology company with a pipeline of internally discovered
investigational drugs designed to address key limitations of
existing cancer therapies.
Turning Point
Therapeutics, Inc
Athena M.
Countouriotis, CEO
Damiva is the women's health company that makes 100%
natural products for women’s health and beauty at any
age.
Damiva
Chia Chia Sun,
CEO and Co-founder
Bavarian Nordic is a fully integrated vaccine company
focused on the development, manufacturing and
commercialization of life-saving vaccines.
Bavarian Nordic
Lee Ann Kimak,
US Commercial Lead
Wanngi
Maree Beare,
Founder and CEO
Wanngi is a health management app that allows you to track
symptoms, immunisations, set medication reminders and
manage medical and fitness information, in one secure HIPAA
Compliant online location
GlamorousAI is bringing drugs to every target though its
AI-first SaaS platform for drug discovery, RosalindAI.
ZAGENO is on a mission to accelerate scientific innovation
by streamlining biotech purchasing processes with its award-
winning, first-of-its-kind e-commerce platform.
Zageno
Natalie Bartlett,
Enterprise Business
Development
Mesa Biotech is a healthcare test and data company that
provides actionable information through trusted, PCR-based
infectious disease testing—anytime, anywhere.*
LEE ANN
KIMAK
Committed to Saving Lives through Exemplary Leadership
“
Our industry is fueled on a constant stream of
discovery which requires talented and creative
research teams as well as the functions needed to
bring new products to market.
“
10 Most Admirable Women Leaders in Biotech for 2021
hip
COVER STORY
“Lowering the risk of infectious disease
for the greater good of our global
community is our main mission.
Lee Ann Kimak
US Commercial Lead
Bavarian Nordic
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As the business world continues to evolve and
disrupt, so does the need for efficient and impactful
leadership. As evident as it could be, leadership is
crucial to a company’s ascension towards the zeniths of
success.
Leadership is an integral part of running any successful
organisation – large or small. The type of leadership needed
may differ depending on what industry you’re in. Still, the
qualities of a good leader remain similar
regardless—having strong interpersonal skills, being
decisive yet open-minded, knowing when to delegate
responsibility appropriately, and leading through example.
We at Insights Care are on a ceaseless endeavour to seek
such impactful leaders. In this edition—10 Most Admirable
Women Leaders in Biotech for 2021—we came across
some of the most accomplished women who’ve left no
stones unturned when it comes to inspiring the world
through their journey towards excellence.
One prominent name among such leaders is Lee Ann
Kimak, the US Commercial Lead at Bavarian Nordic.
Lee Ann joined Bavarian Nordic in January 2020 as the US
Commercial Lead following the acquisition of two
marketed vaccines from GSK. The ability to leverage her
previous experience in vaccines and the integration of
vaccines into a company made this an interesting
opportunity for her.
“Having the opportunity to build a US organisation from
the beginning—building a team, establishing the processes
and infrastructure needed to be successful—was an exciting
challenge for me. The company leadership and culture are
inclusive, collaborative, and agile, which makes it an
enriching working environment,” says Lee Ann.
Good business is about hiring good people;
without them, it is hard to grow and sustain
momentum over time.
“
Setting Benchmarks
Bavarian Nordic is a fully integrated vaccines company
focused on developing, manufacturing, and
commercialising life-saving vaccines. The company’s
fundamental mission is to save and improve lives by
unlocking the immune system’s power.
“We have established a bold vision and aspiration to
become one of the largest pure-play vaccine companies by
2025,” says Lee Ann.
Bavarian Nordic has a strong heritage in vaccine research
and development and proven successful technology.
Innovation remains a cornerstone in developing a strong
product pipeline to help fight existing and emerging
diseases around the globe.
Overcoming Adversities
We asked Lee Ann about the challenges that the COVID-19
pandemic imposed on the global biotech industry and
Bavarian Nordic and how she and her team pivoted to
surpass those challenges. Her response: The pandemic has
spurred global leadership to look to biotechnology and
pharmaceutical companies for solutions to the pandemic,
including diagnostics, assays, therapeutics, and vaccines.
Our industry is uniquely suited for this task as we have
invested in scientific acumen and the regulatory, clinical,
and manufacturing capabilities to deliver these needed
solutions.
“The global COVID-19 pandemic did, unfortunately,
impact many parts of our business. However, a highlight
earlier this year is that Bavarian Nordic reported
encouraging preclinical data for a COVID-19 vaccine
candidate ahead of first-in-human trials.”
“The pandemic also caused business challenges to
collaboration, hiring and of course travel and interactions
with customers. Bavarian Nordic took complete care to
assure that appropriate precautionary measures are in place
and consistent communication and check-ins with our team
members occur.”
“Our top priority is the safety and wellbeing of our team
members, customers, and communities we serve. We
immediately moved to remote working, and like many
companies, became accomplished at leveraging team
platforms to collaborate, hire talent, and interact with
customers. Several working groups across the globe were
formed to evaluate areas of business, including the outlook
for our future workplaces and more flexible ways of
working,” Lee Ann added.
Opinions that Matter
We asked Lee Ann for her opinion on the necessity for
biotech companies to align their offerings with newer
technological developments, which she answered saying,
“As I mentioned before, Bavarian Nordic has a strong
heritage in vaccine research and development, and with a
proven technology, innovation remains a cornerstone in the
development of a strong product pipeline to help fight
existing and emerging diseases around the globe.”
“We are experts in live virus vaccine manufacturing, and
with the recent addition of fill and finish capabilities, we
have enabled end-to-end commercial-scale manufacturing.
Lowering the risk of infectious disease for the greater good
of our global community is our main mission,” she
expressed.
Sharing her opinion on the probable future of the biotech
sector post the pandemic, Lee Ann says, “Our industry is
fuelled on a constant stream of discovery which requires
talented and creative research teams as well as the functions
needed to bring new products to market. Our organisation is
learning how to identify the most creative and talented
teams to focus on bringing innovative products to market,
like an RSV vaccine and COVID booster. When you give a
great team the job of working on these life-saving products
and the tools to do it, they can change the world! You’re
doing something useful for society, which is an incredible
thing.”
A Necessary Change
When asked, what would be things she would change about
the global biotech industry, Lee Ann expressed, “The
pandemic spurred intense government, media, and public
attention on biotech. Maintaining a high level of innovation
and development is critical to the success of our industry,
but we also need to have highly skilled talent in other areas
beyond discovery and development.”
“We need to focus on building and retaining good talent,
managing complexity, and improving commercial and
development execution. Bringing good products and
vaccines to approval is only part of the process. We need to
make sure that we are doing the market development and
otherwise providing the commercial support to assure that
valuable products are accessible to the patients who can
benefit from them.”
Bequeathing the Keys to Excellence
As an excerpt from her professional journey, Lee Ann
shares valuable advice to those aspiring to venture into the
Biotechnology space, saying, “Don’t give up easily is one
piece of advice. Working in small or start-up biotech’s can
be challenging, and there is a new problem to be solved
every day. Resilience needs to be developed as well as a
willingness to operate with a high level of ambiguity and
not a lot of processes.”
“We have established a bold vision and aspiration
to become one of the largest pure-play vaccine
companies by 2025.
Voy
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Voyaging towards New Horizons
Talking about her vision for scaling Bavarian Nordic’s
operations and competency, Lee Ann says, “Currently,
Bavarian Nordic’s RabAvert is the market leader in rabies
vaccination, and we look forward to adding additional
market-leading products to our portfolio in the coming
years. We have multiple product candidates for infectious
diseases and cancer, including candidates for COVID and
RSV, which are large scale programs.”
“Good business is about hiring good people; without them,
it is hard to grow and sustain momentum over time. My
goal is to build on our existing team by adding more
outstanding talent that can make sure we
effectively deliver these products to the market
for the patients who need them,” Lee Ann
concludes.
Stay in touch.
Subscribe to Insightscare Get Insightssuccess
Magazine in print, & digital on www.insightscare.com
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Chia Chia Sun
Mindfully Driving the Revolution in Women’s Healthcare
Chia Chia Sun
CEO and Co-founder
Our mission
is to develop products
that are helping,
not harming, women
with a focus on
prevention.
16|November 2021|www.insightscare.com
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Modern science and the
perseverance and
contribution of several
individuals towards women’s health
have made some significant discoveries
in the sector. The negligence and
ignorance regarding women’s health
and wellness are now being slowly
overcome as people have begun to talk
about it and break the stigma around
the topic.
One prominent name on the list of
people striving relentlessly to improve
women’s health by leveraging science
is Chia Chia Sun, the CEO and Co-
founder of Damiva Inc.
In the following interview, Chia Chia
Sun talks about her inspiring journey in
the women’s health arena, how she
faced the challenges arising from the
pandemic and the prospects of her
firm.
Give us a brief overview of your
journey as the CEO of Damiva and
tell us what inspired you to venture
into the women's health space.
About ten years ago, when I was
perimenopausal - I'm menopausal now
- I realized that there was so much I
didn't know about myself and my
future menopause. I was stunned by
the lack of information - and my lack
of knowledge - about the stages of a
woman's life, our hormonal fluxes, and
our bodily changes.
I started Damiva after a trip to the
drugstore, looking for a product for
vaginal dryness. What I found was that
there was absolutely nothing I wanted
to use because all the products
contained so many chemicals and
toxins. After formulating a 100%
natural product - called Mae by
Damiva - with several partners,
including my husband Gardiner Smith,
who is a protein chemist and lawyer by
training, and a couple of stints on
reality TV shows, Damiva came into
existence.
It became my passion and life mission
to develop products for women that are
good for us for a lifetime, and we can
use them at any age. I decided that, due
to the dire unmet need, I would only
work in women's health for the rest of
my career.
Tell us more about Damiva, its
vision, and the key aspects of its
expertise in health and wellness.
The core vision for Damiva is to create
products that are good for women. To
us, this means 100% natural feminine
care and skincare products that are pH
balanced for each stage of life and - as
a priority - do not contain any
chemicals that are toxic, disrupt
hormones, and contribute to the
climate crisis.
Creating an all-natural, shelf-stable
product is much harder than you might
imagine (think Buzzfeed's Burger
Experiment). So, we have proprietary
formulations and patents that speak the
unique nature of our health and
wellness products. For example, by
removing water from our formulations,
we don't need to use chemical
preservatives and can still maintain a
shelf life of three to five years without
bacterial growth.
From a leadership perspective, what
is your opinion on the impact of the
pandemic on the global healthcare
sector, and how did you aid your
organization to overcome the
challenges rooting from the
pandemic?
The pandemic focused a lot of
attention on the global healthcare
sector and helped create more
awareness of the need for health care
innovation. On the plus side, there is
more capital and consumer acceptance
and adoption of new health
technologies. On the downside, larger
companies benefited from the massive
shift in public opinion and government
funding more than smaller companies.
Our retail revenues were impacted by
COVID-19 due to the drop in-store
traffic by our retailers such as CVS,
Target, and Rite-Aid. We were already
expanding our online sales, and we put
much more effort into the endeavor as
the pandemic unfolded. We realized
immediately that the pandemic gave us
an opportunity to connect much more
closely with our customers, and the
learnings have significantly impacted
our business and improved our product
development.
What is your opinion on the
necessity for health and wellness
companies to align their offerings
with newer technological
developments, especially when it
comes to catering to the ever-
evolving needs of the industry?
A significant lesson from our
expansion of online sales was that our
customer is highly sensitive, not just to
toxic chemicals in formulations but
also to the changing world around us,
including technology, information, and
macroeconomic factors such as climate
change.
Our philosophy at Damiva is to listen
to our customers and their needs.
Accordingly, we packaged our
next-generation products in discrete
sachets (instead of a large bottle),
reducing our packaging footprint by
over 50%.
We also developed a customer-centric
educational membership program that
is entirely online and geared to specific
life stages.
Regarding the alignment of health and
wellness companies with advances in
technology, while I'm personally
invested in innovation, as the
co-inventor on several patents, I
believe that the field of women's health
needs more than innovation; it needs
innovation communication.
10 Most Admirable Women Leaders in Biotech for 2021
17|November 2021|www.insightscare.com
We need to try harder to understand
women's needs, even if these
conversations are awkward or
uncomfortable. We need to break down
the taboos that prevent women from
expressing their needs. Vera Rubin,
who is one of my heroines and should
have won the Nobel Prize for Physics
as the physicist who discovered dark
matter, said it best when she said,
"Don't shoot for the stars; we already
know what's there. Shoot for the space
in between because that's where the
real mystery lies."
What efforts did you and your team
at Damiva take during the pandemic
to sustain operations and ensure the
safety of your employees at the same
time?
Our team is in Canada, the United
States, Europe, and India. While we
were accustomed to virtual business
already, we made the switch from
working exclusively in our Toronto
offices to the entire staff working
virtually from home during the
pandemic.
In your opinion, what could be the
future of the women's health space
post the pandemic? And how are you
strategizing Dative’s operations for
that future?
Women are already the ‘Chief Medical
Officers’ of our households as 80% of
us make the medical decisions for our
families. The women's health space is
already changing post-pandemic as
households are increasingly
accustomed to at-home testing,
diagnostics, and preventive medicine,
with women leading the charge.
The new norm will continue to be
more technology, less travel, and more
local support for women's well-being.
The cons of a post-pandemic era for
women's health are that, while women
took on more of a role at home with
respect to childcare, children's
schooling, and family health, areas
such as career growth and mental
health have suffered. To remedy this,
we women need to spend some time
putting ourselves and our health first.
At Damiva, our future operations post-
pandemic will focus on prevention,
self-care, and the use of technology to
deliver highly informative and
specialized content.
Our mission is to develop products that
are helping, not harming, women with
a focus on prevention. As our products
are completely natural and pH
balanced, they help preserve the skin
microbiome and include preventive
ingredients such as probiotics that are
stable at room temperature.
With respect to self-care, our strategy
for 2022 and beyond is to continue to
have fun with our products while
creating a supportive environment with
our online content membership
program. For example, we will always
have cheeky slogans such as "lip balm
for your other lips" for our labial balm.
Now, we will help women understand
the different parts of the labia and
genital regions and how they change
over time.
In response to inquiries from health
professionals, we have also started a
collaborative Professional Program to
work with pelvic health experts, such
as menopause practitioners, nurses,
physicians, and physiotherapists, to
educate women about our products.
If given a chance, what is the one
thing that you would change about
the global healthcare industry?
I would change the ratio of male to
female leaders in the industry.
Depending on the area, female CEOs
comprise 3% to 6% of the total
number, and this is an appalling
statistic.
To quote Vera Rubin again,
"Worldwide, half of all brains are in
women," and another great quote: "We
all need permission to do science, but
for reasons that are deeply ingrained in
history, this permission is more often
given to men than to women."
As an established leader, what would
be your advice to the budding
entrepreneurs aspiring to venture
into the women's health space?
Just go for it! Feet first, as fast as you
can. We need many more women to
expand this important industry that
affects half the human race.
Pertaining to your role as Damiva's
CEO, how do you envision scaling
your company's operations and
offerings in 2022 and beyond?
One of the major initiatives we put into
place during the pandemic was to
redesign our packaging to withstand a
variety of extreme temperatures that
we are experiencing with global
warming and climate change. This
redesign will enable us to grow quickly
and scale our operations in North
America and beyond. We are
partnering at home here in the U.S.
with our manufacturer to be the largest
100% natural women's health company
globally.
First and foremost, as always, our
offerings continue to put women first
by giving women what we need and
want: completely natural, vegan,
ethical, and sustainable products that
are free of hormone disruptors and
toxins.
18|November 2021|www.insightscare.com
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Maree Beare
An Ardent Advocate of Digital Transformation of
the Healthcare Industry
Founder and CEO
20|November 2021|www.insightscare.com
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Modern hospitals and clinical
institutions have become
increasingly reliant on
healthcare software systems. Touch
screens, tablets, and internet reports
have quickly replaced paper-based files
and written patient information. All of
this has been made possible by huge
advances in the realms of information
technology. Technological
improvements have made life easier
for hospital administrators around the
world.
The requirement for a comprehensive
patient information system spawned
the concept of healthcare management
platforms. The primary focus of these
platforms is managing patient records.
The demand for healthcare
management solution is attracting
many entrepreneurs to develop such
platforms. To cater to this demand,
Maree Baeree an enthusiastic
entrepreneur established her companies
Wanngi and Clinials, to track and
communicate the health of people.
Maree Beare is a sector leader in
HealthTech, Femtech, and Biotech, and
has been listed by Forbes in the top 50
women-led startups disrupting
Healthtech. She has over 30 years
innovation experience, navigating
global software companies and
executed many large and high-profile
projects to meet company and
government strategy. Maree now
brings this leadership to the Startup
and Innovation sector and the
healthtech, femtech, and biotechnology
sectors globally.
The Inception Story of Wanngi and
Clinials
In 2017, Maree created Wanngi when
she realized that it was a problem for
consumers to make decisions about
their own health when they had no
access to their own health data. “I
imagined a world where people could
improve their chances of being
diagnosed by providing their health
history to the various doctors and
hospitals they might see during their
life,” says Maree.
Maree is of the opinion that hospitals
and doctor’s health systems are not
connected, resulting in people having
to repeat their health history over and
over at each health appointment
leading to miscommunication and
misdiagnosis.
Fast forward to 2020, Maree’s husband
went on a clinical trial and was
required to report any adverse events
by completing a paper form. Opening
Maree’s eyes to the issues with
participating on clinical trials where
lifesaving treatments are not making it
to market as 80% research trials fail to
find enough people.
In 2021, Maree launched Clinials,
providing efficiencies in the $47
Billion clinical trials market by
disrupting the existing study
participant recruitment process, so
people are getting access to more
effective treatment sooner. “We aim to
Enhance patent recruitment per clinical
trial to improve site economics for
clinical trials leading to Improved
treatment and patient outcomes and for
many, this means improving life
quality (QALY),” shared Maree.
Braving the Pandemic
During the outbreak of the COVID-19
pandemic, Maree and her team
switched to working from home and
returned to the office only when
officials allowed. Maree believes that
the pandemic has sped up innovation in
healthcare due to the dire necessity. It
led to the increased use of telehealth
for safety and convenience of
continued care.
I imagine a world
where people could
improve their
chances of being
diagnosed by providing
their health history
to the various doctors
and hospitals they
might see during
their life.
10 Most Admirable Women Leaders in Biotech for 2021
21|November 2021|www.insightscare.com
The pandemic has escalated the need
for decisions around a person’s health
status and the requirement for access to
COVID-19 test results and vaccination
status. There’s a great deal of noise and
uncertainty about accessing this data
for consumers.
However, Wanngi is fit for purpose as a
consumer personal health record, so it
was ready and able to store and
provide evidence of COVID-19 tests
and continues to help people provide
their health history during a telehealth
appointment.
However, with the focus on COVID-
19, the health management of people
with chronic illness declines and the
aftermath of pandemic will see a
burden of late-stage chronic illness on
the healthcare system. Clinials will
provide the platform to connect these
patients to any clinical trial relevant to
their health conditions, where they
meet the inclusions and exclusions of
the study.
Leveraging Technology
When asked for her opinion on the
importance of technology in the
healthcare industry, Maree says,
“Companies seek to be economically
sustainable, and healthcare is no
exception. Technology will drive
efficiencies in healthcare as well as
improving patient outcomes with AI
and innovation, and in the future, it
will continue to develop in dramatic
ways.”
“While we can take a glimpse and
debate the details of future trends in
healthcare, we need to be clear about
the drivers so we can align with them
and actively work to ensure the best
outcomes for society as a whole,” adds
Maree.
Maree aspires to overthrow the
misconception that investment cycles
in healthcare are the same as traditional
investments. “History tells us that it
takes 10 years to be an overnight
success in Healthtech,” she added.
Envisaging Future Endeavors
Clinials is uniquely positioned to
secure product led growth moving
forward into 2022 and beyond. Having
raised pre-seed funding in 2021 and
preparing for a larger raise in early
2022, the company is ready to expand
the team to support its customers. It is
focused on building the innovation
roadmap to decrease cost of trial
marketing, recruitment and leveraging
Machine learning and AI to accelerate
product-led growth and continue
Clinials customer retention.
“I have already delivered on the future
strategy by launching Clinials this year
in response to the opportunities of
Australia being relatively COVID-19
free, and there being a verified problem
to solve with participant recruitment in
clinical trials to enable Australia to be
globally competitive in research of
new treatments,” concludes Maree.
22|November 2021|www.insightscare.com
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24|November 2021|www.insightscare.com
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STEM Fields
STEM Fields
#Closingthegap
Science, technology, engineering, and mathematics
(STEM) fields are significantly important to power
innovative advancements and enhance technological
developments. These are the factors that in turn are seen as
drivers of social and economical growth.
As a result, researchers and policymakers are paying
substantial attention to analyse and promote high-growth
ventures in STEM fields. The consistent analysis has
resulted in making STEM a valuable part of education in
universities and also in the accommodation of jobs in
developing countries.
As every coin has two sides, one of the major criticisms of
STEM has to do with the gender disparity in students who
graduate with STEM degrees and enter career mainstreams
related to these fields.
Research data has conventionally displayed that 'women are
far less likely to graduate with a STEM degree or enter a
mainstream career in this field,' when compared to their
male opposite number.
Vanquishing a Gender Gap
Proponents of closing this gender gap in the STEM field
points out that this gap not only reflects unfair conditions
and poor treatment of women in this field. Furthermore, it
also reduces the quality of work and innovations being
extracted from these fields.
It is a subject of recommendation and facts that indicate
scientific progress relies on unique solutions that are
emerging from different perspectives. Closing the gender
gap make STEM fields more diverse, also, redefines the
assurance of problem-solving approaches with a variety of
different perspectives.
Although the broad gender gap that exists across the STEM
fields becomes a topic of discussion, there is a great deal of
variety among different STEM subfields when it comes to
the exact scale and nature of this gap.
Some subfields have no gap at all and favour women in
graduation, and job placement. In subjects like social
science, there is a greater number of women if compared to
men, and it remains strongly favourable towards women.
25|November 2021|www.insightscare.com
Enabling Innovations
It is a fact of assurance that women would benefit from the
creation of more inclusive atmospheres in STEM fields,
these fields as a whole can become more engaging.
A field like science works and functions at its best when it
considers a wide range of diverse perspectives. By
excluding women, such fields not only exclude a wide
range of extremely talented future leaders but also fresh
perspectives that could be used to create innovative
approaches to resolve problems.
Engaging women in stem fields has improved the quality of
work being executed in those fields and it has opened up
distinguished career opportunities for women.
In general, research has displayed that, 'diverse workplaces
are happier in nature and more productive,' indicating that
STEM organizations could do better for themselves by
being more inclusive.
Breaking the Stereotypes
The idea of the gender equality paradox is not without its
problems. Critics point out that countries with poor
representation in STEM fields have a long history of
excluding women from science and mathematics, which has
been deeply embedded into the culture that surrounds
young girls as they are growing up.
They also point out that there is no gap in ability since
researchers found that girls performed as well or better than
boys on STEM tests in most countries.
True solutions to the gender gap in STEM fields work on
multiple levels. Exclusion begins in childhood, when young
girls have been pushed away from creative fields like
science, and mathematics, and are encouraged to adopt
more care-oriented work.
This scenario is drastically changing as parents are
encouraging and reminding their children that they can
grow up to do anything that they want. Parents are also
providing a wide range of opportunities for children to
explore their interests, including those related to STEM,
such as coding camps and science fairs.
In education, scholarships and grants are striving hard to
bring women into STEM departments. However, these
departments must do everything in their power to prevent
discrimination and sexism against female students to
improve preservation rates.
In the workplace, employees must identify and address the
discrimination in their hiring practices so they can generate
a diverse workplace that enhances productivity among their
employees.
Outside of school and the workplace, broader societal
changes are also called for. Women are often harder hit by a
couple's decision to raise a family, forcing them to take
more time off of work during critical periods in their
careers, such as early on at a new job or even during their
doctoral studies.
Despite these situations, women are making noteworthy
progress not only in STEM fields, but also in their
profession, and are breaking the stereotypes.
The Profound Leaders in STEM
Many women have made significant contributions to our
understanding of the world and these contributions are now
being recognized as an example for the young generation.
Below are just a few of the women who have changed the
world with their knowledge and expertise in STEM fields.
Ada Lovelace
Ada was one of the early computer scientists. Her work was
instrumental to the advancements of early computer science
as she developed an algorithm for Charles Baggage's
analytical engine that would output Bernoulli numbers.
Marie Curie
Marie Curie is recognized as the most inspirational female
scientist of all time. She was the first person to win the
Noble Price twice in her career. Marie's work involved
radioactivity, including the discovery of a few radioactive
elements.
Rosalind Franklin
Rosalind was an English chemist whose work on molecular
structures established a foundation of our comprehension of
the fundamental workings of things like DNA, RNA, and
viruses.
Sally Ride
Sally Ride was an astronaut, engineer, and physicist. Sally's
position as the first American female astronaut and the third
woman to travel into space, as well as her science books
aimed at children, have created the legacy of an
inspirational figure for many young women and girls
interested in STEM fields.
The Journey Ahead...
Although increasing comprehensiveness for women in
STEM has recently become a trending topic, women have
been making waves in STEM fields since humans began to
examine the natural world.
One way to bolster the ranks of future women in STEM is
to acknowledge the contributions women have made in the
subfields of STEM in the past.
- Abhishek Joshi
26|November 2021|www.insightscare.com
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Natalie Bartlett
Chauffeur of Modern Change in the Biotech Industry
Pharma R&D is one of the most
booming industries that always
supported the world even when
the pandemic hit it; thanks to its
bloodline, the leaders of lab supply
chain companies have always kept it
running. In the last few years, the
biotechnology industry has witnessed
digitalization and enhancement of
technology in its every code of conduct
as people are looking for an advanced
way of coxswaining everything.
The demand for digitalization in the
biotechnology supply sector is very
28|November 2021|www.insightscare.com
Natalie Bartle
Enterprise Business
Development
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high as many are still following the
same outdated method of purchasing
lab supplies with catalogs, fax,
telephones, and so on, and buyers are
looking for a better alternative.
To fulfill this need of the
biotechnology industry, one of the
prominent leaders Natalie Bartlett, the
Enterprise Business Development
of ZAGENO, has worked very hard to
solve many issues through the
company's in-depth solutions. These
include online monthly spending data,
comparison of products, best
alternatives, tracking order status, etc.,
making the industry's procedures
extremely convenient. Also, by
eliminating various steps, Natalie
Bartlett has given her best to save her
client's time and money potential by
developing the company's top services.
In the following interview, Natalie tells
us about the various challenges she
sailed through to provide ZAGENO's
clients with excellent services.
Following are the highlights of the
interview:
Give us a brief overview of your
journey through your role at
ZAGENO, and also tell us what
inspired you to venture into the
biotechnology sector.
I started working in venture capital and
focused on early-stage startups within
life sciences and software. Growing up
in a family of healthcare providers, this
was a good fit because I always had an
interest in the space. While at General
Catalyst, I sourced and invested in
ZAGENO, a startup reimagining life
sciences commerce with an initial
focus on R&D supplies.
I found myself intrigued by how
outdated purchasing products for lab
supplies was and how a team and
technology like ZAGENO's could help
solve this. I decided to roll up my
sleeves and help make a direct impact
on myself. Today, I work on
ZAGENO's enterprise business
development team, focusing on helping
large pharma organizations improve
their research efficiency when ordering
supplies.
Tell us more about ZAGENO, its
vision, and the key aspects of its
stronghold in the global
biotechnology space.
ZAGENO's vision is to accelerate the
time between scientific milestones.
While simple to articulate, it is quite
complex in executing this vision. It
begins by completely rethinking the
industry's lifecycle, which begins with
identifying where other business
markets have successfully transformed,
modernized, and automated. We
sometimes take the kernel of other
innovations and customize them for
biotechnology.
Our interpretation of the well-
established subscriber model is
experienced through ZAGENO's
marketplace and services. Through it,
our subscribers benefit from various
unique advantages such as data on
historical spending, detailed product
comparisons, and alternatives to
products on backorder or with long
lead times.
At a high level, ZAGENO seeks to
democratize the buyer-seller
relationship through lab supplies - the
very lifeblood of scientific discovery.
Historically, this part of the industry
was dictated by manufacturers and
distributors. Without an alternative,
scientists had little choice but to accept
this status quo. But just as the
subscription economy has redefined the
buyer-seller relationship in consumer
markets, so is it changing these
relationships in biotechnology.
The future of the industry will be a
more harmonious one, equally dictated
by manufacturers and users. Because
ZAGENO provides a platform to
support this evolution, we are at the
epicenter of this change.
From the business development
perspective, what is your opinion on
the impact of the pandemic on the
biotech space? How did you aid your
organization to overcome the
challenges rooting from the
pandemic?
From ZAGENO's perspective, the
pandemic has divided the industry into
groups of haves and have nots. The
thing that is often overlooked is the
running cost of biotech, which can
range from $10,000-40,000 per day.
So, any downtime in productivity can
have profound business implications to
the bottom line.
COVID's impact on the supply chain
caused some labs to go dark and their
scientists to be furloughed. But
biotechs that subscribe to ZAGENO
benefit from access to a marketplace
10 Most Admirable Women Leader in Biotech for 2021
29|November 2021|www.insightscare.com
.
where they are able to forecast
accurately and manage supply levels
and face challenges like backorders
and extended lead times with suitable
alternatives to ensure labs remain open
and productive.
What is your opinion on the
necessity for biotech companies to
align their offerings with newer
technological developments,
especially when catering to the ever-
evolving healthcare needs?
While focusing on investing in early-
stage startups at the intersection of life
sciences and software at General
Catalyst, I witnessed the burgeoning of
startups looking to accelerate the drug
discovery process from R&D through
clinical and beyond.
In my opinion, the software has not
impacted the life sciences field in the
same way it has in other industries, so
the opportunity to accelerate the drug
discovery process (which today
averages ten years) through the use of
the software is immense.
For R&D purchasing in particular
(ZAGENO's focus), a vast majority of
research scientists are still purchasing
supplies in the same way consumers
purchased goods in the 1970s! They
are still phoning and faxing in orders
via paper catalogs. While today's
consumers can buy groceries in one
click and have them arrive the same
day, scientists spend 4-8 hours just
finding and purchasing supplies. If
technology can reduce wait times from
weeks to days and even hours, imagine
the savings potential, both in time and
money, of the drug development
process at large!
Through your role as Enterprise
Business Development, what efforts
did you and your team at ZAGENO
take during the pandemic to sustain
operations and ensure the safety of
your employees at the same time?
As you may imagine, the demand for
R&D supplies during COVID has been
immense. As our team transitioned to a
work-from-home setup, our order
volume simultaneously skyrocketed.
Personally speaking, I cannot imagine
starting a new role or even a first job
completely remote! But with half of
ZAGENO based in Berlin, we were
already accustomed to remote
collaboration through video meetings,
slack, and other web-based tools. To
further support a work-from-home
environment, our team also focused on
several initiatives, such as new daily
and weekly stand-up meetings.
We also provided our leadership with
resources for remote management and
guidelines for remote work to all
employees. To provide additional
support for new employees, we
established a buddy system so that new
hires had a dedicated ZAGENO alum
as a resource. For all employees,
ZAGENO also sent care packages to
ensure everyone had proper at-home
office and technology setups.
Despite a majority of ZAGENO never
having met one another, as a company,
we have been quite productive, which
is evidenced by a doubling in revenue
over the past year.
In your opinion, what could be the
future of the biotech sector post the
pandemic? And how are you
strategizing your organization's
operations for that future?
30|November 2021|www.insightscare.com
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We have witnessed a few trends during
the pandemic for remote lab work,
which I believe will continue in the
future.
After the initial closure of research
labs, we saw that research scientists
began to return for critical work only,
splitting into teams to reduce risk and
performing all operational
management remotely.
It became even more critical that
supplies were there for research
scientists when they did spend time in
the lab, especially amidst an increase
in product backorder rates. I believe
that remote lab management will be a
long-lasting effect of the pandemic,
even beyond just ordering supplies.
ZAGENO is strategizing its operations
to enhance these capabilities through
mobile optimization and integration
into inventory management solutions.
Meanwhile, our operations and
customer success teams are equipped
to support research scientists whether
they are at the bench or at home.
As an established leader, what would
be your advice to the entrepreneurs
aspiring to venture into the biotech
space?
For entrepreneurs looking to build
software companies in the life sciences
space, in particular, my biggest advice
would be to create a well-rounded team
with experience from both the life
sciences and software industries.
Given that startups in this space are
still emerging identifying and hiring
individuals with blended expertise is
quite challenging. However, there is
unique knowledge from both sides that
needs to be combined in order to build
a successful company, so instilling this
balance through your team from the
start as well as while you grow is
essential.
How do you envision contributing
towards the goal of sustaining your
company's stronghold in 2021?
I have recently taken on a role in
enterprise business development, with
a particular focus on enhancing their
purchasing experience for the
industry's largest pharmaceutical
companies.
In this time, I've witnessed the huge
trend happening across pharma R&D
to provide a superior user experience,
consolidate buying channels, and drive
digital adoption for both time savings
for research scientists and cost savings
for the research team at large.
Building supply and demand are
crucial to winning the market with any
new subscriber service (e.g., a
marketplace). I believe that working
with large pharma will not only drive
our stronghold within the market to
realize our company's full potential but
will also simultaneously bring
efficiency to the lengthy R&D drug
development process. It's a true win-
win, which aligns with ZAGENO's
greater mission to accelerate life
sciences.
31|November 2021|www.insightscare.com
Noor Shaker,
Senior Vice President,
and General Manager
Our focus on hiring
self-motivated, highly
productive individuals has
certainly helped us scale
while sustaining
healthy growth.
34|November 2021|www.insightscare.com
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Amidst the ongoing pandemic, AI-driven drug
discovery has been at the forefront of the
healthcare sector, consisting of molecular features,
interactions, and behavior in order to build better materials,
processes, and systems for specific purposes. Traditional
processes require clinical trials on patients to investigate the
efficacy and optimum combination of drugs or dosage in
developing viable therapies. But an AI-based drug
combination therapy is proving to be a critical technique for
identifying optimum and effective regimens.
AI accelerates the drug development process along with
saving time, money, and human efforts. In short, it is a
catalyst that speeds up drug discovery. Hence, the
implementation of AI in the healthcare space has become a
go-to option for pharmaceutical companies and their leaders
who are aspiring to dominate the drug discovery market.
While many such health leaders are charting strategies for
the healthcare sector, we came across Noor Shaker, the
Senior Vice President and General Manager of
GlamorousAI, who chose to take the unbeaten path.
In an interview with Insights Care, Noor sheds light on the
journey of her company, its services, and how the adoption
of AI is transforming the healthcare sector.
Noor, give us a brief overview of your journey through
your role at GlamorousAI and also tell us what inspired
you to venture into the biotechnology sector.
My journey started as a computer science engineer in my
home country, Syria. I got fascinated by Artificial
Intelligence early on, and I realized that the field would
have a great impact on so many aspects of our lives. I,
therefore, decided to pursue a career in AI, and that led to
my assistant professorship in AI from the Aalborg
University of Copenhagen.
The time at which I got my assistant professorship
coincided with the heartbreaking passing of my mother
after a long fight with lung cancer. Shortly after, I decided
to drop my academic position and focus on the translation
of AI research to the drug discovery space. I co-founded
Glamorous AI in 2020 to deliver on my mission to cure
diseases with the power of AI.
Tell us more about GlamorousAI, its vision, and the key
aspects of its stronghold in the global biotechnology
space.
GlamorousAI’s vision is to bring drugs to every disease. We
are doing this through innovative AI solutions that are
data-efficient and through putting these tools in the hands of
drug hunters. Our AI allows us to extract information and
patterns about the disease and potential drugs from
challenging datasets.
This is a key in biomedical research where data is usually
noisy, unbalanced, and small. We’ve recently joined forces
with X-Chem, a leading service provider in the
Shaker An Ardent Advocate of
AI-driven Drug Discovery
10 Most Admirable Women Leaders in Biotech for 2021
35|November 2021|www.insightscare.com
DNA-Encoded Library space, and we believe that together,
we can bring AI, data, and expertise under one roof to
provide the best services to the pharmaceutical industry.
What is your opinion on the impact of the pandemic on
the biotech space, and how did you aid your
organization to overcome the challenges rooting from
the pandemic?
I think the pandemic had a positive impact on the biotech
sector; it certainly increased the public awareness of the
field and the difficulties associated with the discovery of
new medicines. Glamorous AI’s inception was just after
COVID-19 hit, and that meant that we had to build a remote
working environment and culture from the get-go. That has
actually helped us build a global hiring strategy and tap into
the international talent market.
What is your opinion on the necessity for biotech
companies to align their offerings with newer
technological developments, especially when it comes to
catering to the ever-evolving healthcare needs?
I think the biotech industry needs to keep up with the fast
pace of innovation to ensure the best outcomes for patients.
Startups and small businesses in this sector are leading the
way with innovative solutions that will soon become the
mainstream to how we discover and treat patients.
Through your role as SVP and General Manager, what
efforts did you and your team at GlamorousAI take
during the pandemic to sustain operations and ensure
the safety of your employees at the same time?
We have a great multidisciplinary team of international
experts located in different geographies. We have been
hiring for remote positions since the company’s inception,
and that meant that we needed to put processes in place to
ensure clear communication and a healthy, scalable culture.
Our focus on hiring self-motivated, highly productive
individuals has certainly helped us scale while sustaining
healthy growth.
In your opinion, what could be the future of the biotech
sector post the pandemic? And how are you strategizing
your organization’s operations for that future?
It became evident just over the past year, or so that AI will
play a big role in how we develop new cures. AI innovation
and adoption in the biotech sector are set to increase over
the next few years. I believe success in this sector will be
led by organizations who understand the multidisciplinary
nature of innovation required and, therefore, the need to
build cohesive multidisciplinary teams.
I’m also a believer in open innovation and that AI tools and
advancements should be integrated with every drug
discovery program. We are therefore focused on not only
building best-in-class AI but also on democratizing access
to our AI solutions through our SaaS platform, RosalindAI.
As an established leader, what would be your advice to
the entrepreneurs aspiring to venture into the biotech
space?
Personally, I find the biotech sector one of the most, if not
the most, exciting fields to be in. It combines the social
drive of improving human lives with the intellectual cursory
necessary to find innovative ways to advance science.
How do you envision scaling your company’s operations
and offerings in 2022 and beyond?
We are looking to enable every drug hunter with the best-
in-class AI solutions to drive the discovery of more
effective medicines. To deliver on this, we are hiring the
best talent and expanding our customer base to enable the
democratization of AI in drug discovery.
36|November 2021|www.insightscare.com
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Biotech
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Tech Trends
Shaping the
Top
iotech Innovations: Casting a new net
B
Pandemic brought Biotech from the shadows to the
limelight. The industry which was earlier catering mostly to
medicine, biopharma, and healthcare, is now opening for
consumers of Biotech and customers of Biotech.
They have already been re-casted by scaleups and start-ups
in developing repurposed drugs, rapid testing kits and
vaccines. US remains the main Biotech Innovator
worldwide. And US is again casting a new net of Biotech
Innovation, with huge investment pouring in from both
public and private sources.
Biotech Trends: Shaping an Industry
The novel innovative threads (read trends) of this net are,
#AI (Artificial Intelligence): Start-ups are using
Automation for discovering the treasure of new drugs,
products, and processes and screening biomarkers. They are
also using Image classification algorithm to detect different
38|November 2021|www.insightscare.com
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traits (like crop disease symptoms from leaf images and
cancer cells from medical scans) quickly.
Furthermore, start-ups are developing rapid diagnostics,
analyzing microbiomes, and screening phenotypes by
leveraging deep learning. Firms are also developing RNA
platform which are guiding therapeutic development.
While others are identifying genetic markers which
analyzes genomic data to understand genetic mechanism of
a trait and then developing applications for novel drug
39|November 2021|www.insightscare.com
design, plant and livestock breeding, and diagnostic
development.
#Big Data and Analytics: This solution is enabling start-
ups to tap into ever growing wealth of data coming in from
omics tech, sensors integration, and IoT (Internet of Things)
devices. This allows such firms to recruit patients and
perform clinical trials on them more effectively. It can
further find out suitable and safer treatment regimens as
well as develop such regimens from disparate and
unstructured data sources. They can also deploy such
solutions to develop better feed, explore yet undiscovered
microbes and improve varieties of crop and livestock.
Firms have developed a platform of genomic data analytics,
by using a data library, to manage all data, samples, and
modules, and run bioinformatic pipelines via cloud
computing.
#Gene Editing: Today instead of genetically modifying
organisms, gene editing can precisely and efficiently edit
genome, leveraging developments in CRISPR (as molecular
scissors), and engineered nucleases to treat genetic
disorders by editing (adding, replacing, and/or silencing)
that gene. This can also create genome edited and
transgenic plants, and animals.
There is also a next generation delivery tech, where
chloroplast engineered traits are integrated into breeding
processes suitable for engineering of metabolic pathways
and modification of photosynthetic pathways.
#Precision Medicine: Biotech start-ups are leveraging this
solution to discover new drugs, identify novel targets,
develop new drug delivery tech, and offer gene therapies.
There are also patient-centric, AI-powered gene therapies
and drug development programs for non-invasive, precise,
and personalized drug delivery mechanisms and gene
therapy vectors.
#Gene Sequencing: The reduced cost of gene sequencing
has opened a wide range of applications like large cohort
setups with extensive phenotyping, identification of
pediatric disorders, personalized treatments, detecting
microbes' presence (pathogens in clinical, beneficial soil
microbes).
By using defined input sequences, start-ups are providing a
solution for the quick and accurate identification of active
COVID-19 infections.
#Biomanufacturing: Utilizing biological systems it
produces medical products and therapies, food and
beverages, biomaterials, and specialty chemicals. To make
it inexpensive and scalable, startups are advancing
recombinant production technologies, fermentation, and
different cell culture.
The sustainability is enhanced by using biological raw
materials. The industry's production models are also
adopting machine learning and automation. Integrating
Industry 4.0 models of automation and machine learning,
startups are offering bioprocessing 4.0 to optimize each
stage of the production process.
#Bioprinting: By utilizing bioprinters which work with
bio-inks developed from bio-based and biomaterials
extracted from patients own cells, start-ups are enabling
skin, bone, personalized medicines, and vascular grafts
development.
#Synthetic Biology: It offers increased standardization and
reproducibility, allowing organisms manipulation at the
gene networks level. A high yield of valuable biochemicals
is provided by bacterial cell factories with applications in
food, pharma, and materials. Moving beyond microbes,
mammalian synthetic biology solutions are also in
development.
#Microfluidics: LOC or lab-on-a-chip devices needs
microfluidics. These miniature labs facilitate POC or point-
of-care diagnostics, quick and inexpensive testing of
infectious diseases.
For diagnostics and environmental monitoring, start-ups are
also developing paper-based microfluidics. The tech finds
more biopharma applications in OOC or organ-on-a-chip
devices, which simulate the physiology of organs/organ
types on little chips. OOC systems are useful in disease
modeling and drug screening.
#Tissue Engineering: Due to developments in Bioprinting,
Synthetic Biology and Microfluidics, Tissue engineering
enables regenerative medicines, treatment of burns, and
organ transplant by creating grafts of autologous tissues. To
create sustainable alternatives to meat, leather and such
animal products, start-ups are using tissue engineering
widening its scope from limited biomedical applications.
Touching New Horizons:
The most impactful trends from the list are AI (with 26% of
the Biotech sector impacted), Big Data and Analytics
(19%), Gene Editing (12%), and Precision medicine (10%).
The remaining 33% shows impact of the rest from Gene
Sequencing to Tissue Engineering. Surely Biotech is rapidly
touching new horizons of our modern life.
40|November 2021|www.insightscare.com
,
and
als
n
nt-
are
s
p
ng,
To
.
% of
%).
idly
Radiology
and
Imaging
5
trends in
- by Meenakshi Singh, Co-founder and CEO, Synapsica
With the growing popularity of minimally
invasive procedures, there is a rising demand
for accurate and efficient imaging technologies
in both developed and developing countries. Radiology is
one branch of diagnostic imaging that has kept up to date
with the technological advances.
In this year's conference of Radiological Society of North
America, a society formed by radiologists and health
scientists around the world, revolved
the discussions mainly
around technology and its adoption. The general trend is
that Healthcare as an industry is quick when it comes to
adapting to innovations and radiology as a subfield leads
this change.
Technological advancements, in the past few years, have
led to major changes in the radiology industry and delivered
crucial advantages to both the radiologists and the patients.
Many radiologists and radiology centers today are
employing AI to assist them for faster, more accurate and
subjective reports.
AI can easily spot a difference, as small as .001
micrometers, something which is not possible for the
human eye to detect. It is because of this reason that
radiologists and radiology centers that provide AI generated
reports are seeing an uptick in the number of doctors
approaching them for more reliable reports in the fastest
possible time. In fact, when it comes to emergency and
trauma cases, a 3X jump has been seen for AI powered
reporting requests over the last few years.
Other than the benefits of subjectivity, speed, remote
reporting and more accuracy that AI is bringing in the
radiology reporting, AI is also making it possible to detect a
number of health issues precisely that are difficult to predict
via traditional routes, like breast cancer, hemorrhagic stroke
and lung cancer and spine degenerative diseases in advance
and researches are on to detect more health issues that get
missed especially at early stages.
Also, thanks to technology, more and more radiologists are
able to work remotely and handle almost 3X more caseload.
Earlier, a lot of their time used to get lost in travelling to at
least 3-4 centers in a day. It's a great support to the
healthcare infrastructure in the country especially during
the ongoing COVID pandemic when everyone must remain
home to contain the spread.
With these ongoing advancements and the potential in the
field, lets look at a few trends in the Radiology and Imaging
industry that we can expect in 2022.
Trend #1 - AI in healthcare
The pandemic accelerated the clinical adoption of AI. AI
applications which were considered experimental
applications pre-pandemic are now an integral part of
44|November 2021|www.insightscare.com
y
gsica
ct a
dict
oke
nce
et
are
oad.
at
ain
e
ging
Meenakshi Singh is the Co-founder
and CEO at Synapsica, a health-tech
platform for automating clinical and
back-office radiology processes.
Synapsica's AI based solutions
automatically generate clinical
interpretations of radiology scans
right after the image capture, without
any radiologist intervention.
Meenakshi founded Synapsica in 2019
along with her co-founders, Kuldeep
Singh Chauhan (CTO) and Dr Cherian
(COO). She is responsible for
fundraising, marketing and leads
efforts for clinical validation and
international regulatory compliance of
the company's products. Under her
aegis, Synapsica has helped in
examining more than ten lakh
patients.
Before starting her entrepreneurial
journey, Meenakshi worked with
multiple giants including - Google,
LoanIQ, Manhattan associates and
Goldman Sachs. During her four years
stint at Goldman Sachs, Meenakshi
was instrumental in building quant-fin
data analytics solutions to detect and
prevent fraud and manipulation in the
US financial markets for fixed income
securities and complex derivatives.
Time after time, Meenakshi has
proven her tech acumen by
implementing technology led changes
in multiple companies.
Meenakshi is a postgraduate from IIM
Ahmedabad and pursued B.E
Computer Science from Manipal
Institute of Technology. She is an
ardent mountaineer, and her goal is to
climb mountains 6000 meters and
above.
About the Author
45|November 2021|www.insightscare.com
clinical reporting flows in several large-scale medical
centers.
AI can be used for various functions such as diagnosis,
triaging and workflow automation. Many organizations are
looking to integrate AI and accelerate its usage for
diagnosis.
Trend #2 - Advances in imaging scanners and
Hyperautomation
Imaging scanners today are providing much in-depth
information about a patient's body. For instance, Siemens
PCD (Photon Counting Detector) CT machine, which was
unveiled at this year's RSNA conference, can provide
substantially better contrast and spatial resolution for near-
realistic, cross-sectional images – a which means the
system can capture even the most minute anatomical
structures in a patient's body like- the smaller bronchi of the
lungs or metastases in bones.
This technology further reduces radiation exposure for
patients while providing better diagnoses and hence
opening up more use cases for CT scans. This is something
which was unthinkable till just four years ago.
Similarly, MRI and x-rays motion scanners today are using
AI-based image reconstruction techniques which makes it
much more economical and uncomplicated to maintain.
Usage of advanced modalities has already increased by
43% and these advancements promise to further support
this trend and further entrench diagnostic imaging in patient
management protocols.
Hyperautomation
India has only 10,000 radiologists for a billion people. This
shortage means that radiologists work overtime to report.
However, technology has brought in an easier way for
healthcare professionals to reduce their work by automating
tasks. This is known as Hyperautomation.
Advanced technologies such as AI and ML automate
numerous tasks bringing down the rate of error and
allowing professionals to concentrate on important cases. In
fact, it is expected that by 2024, organizations can bring
down their operational costs by 30% through the
combination of Hyperautomation and redesigned
operational processes.
Trend #3 - Cross-discipline Collaboration Within
Departments
The internet has forever changed the healthcare landscape.
It allows data to be shared through web APIs, enabling
cross-disciplinary collaboration and knowledge pooling.
With specialists collaborating with other healthcare experts,
radiologists can apply integrated diagnostics using digital
technology and move towards digitally reviewing images.
Trend #4 - Telemedicine and teleradiology
COVID-19 has created a need for telemedicine and
teleradiology with even in-house panels reporting remotely.
Traditional in-house PACS are being replaced with imaging
systems that allow for collaboration remotely. There is an
increasing need in healthcare for professionals to be able to
access the patients records remotely and from across
departments.
Trend #5 - AI Orchestration
AI orchestrations are the newest addition to the suite of
software solutions available for the radiology industry. AI
orchestration provides organizations with intelligence to
automate the daily operations of the business. This helps
reduce repetitive tasks and the workload of professionals
enabling them to focus on specific cases.
46|November 2021|www.insightscare.com
it
ient
his
.
ing
. In
pe.
rts,
al
s.
ely.
ing
n
e to
AI
s
10 Most Admirable Women Leader in Biotech for 2021.pdf
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10 Most Admirable Women Leader in Biotech for 2021.pdf

  • 1. #Closingthegap The Gradual Rise of Women in STEM Fields New Horizons Top Tech Trends Shaping the Biotech Industry LEE ANN KIMAK Committed to Saving Lives through Exemplary Leadership Most Leaders in for 2021 Admirable Women Biotech 0 NOVEMBER ISSUE 04 2021
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  • 4. do not know what I may appear to the world, but to Imyself, I seem to have been only like a boy playing on the sea-shore and diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, whilst the great ocean of truth lay all undiscovered before me.” In this quote, Sir Isaac Newton believes that even though our knowledge of the universe has expanded, it still stands on the shore of the 'Great Ocean of Truth'. We are yet to uncover the tiniest part of the wonders the universe holds. But more importantly, there seems to be a strong desire in humans to constantly expand this body of knowledge because of the historical scientific wonders achieved so far. From cloning of 'Dolly the Sleep' to 'Resurrection of Species,' biotechnology has made it possible to discover great marvels of science to be specific. One such wonder was the discovery of mobile genetic elements done by Dr Barbara McClintock in the year 1951. Her research on plant breeding and genetic engineering made her win the noble prize in Physiology, in 1983. That's around three decades later! Well, why do you think so? Dr McClintock's work was 'ignored' for many years by her peers in the scientific community. In the face of such resistance, she stopped trying to convince people about her discoveries but never stopped pursuing her theories. Until a decade after her discovery, the scientific community began to come up with the same conclusions and validated her findings by giving her the credits that were long due. She was a woman who changed science. Likewise, multiple women are fighting against the odds and making a big difference in the biotech industry. They have ensured that the momentum doesn't die out. Women have worked with passion, zeal, and an innovative approach. As this awareness is growing, the biotech industry is taking strides to encourage and represent women within the industry. In this edition, 10 Most Admirable Women Leaders in Biotech for 2021, Insights Care has enlisted women who have significantly impacted the biotech industry. By highlighting this, I believe it is important to note that women are not just demanding space in the industry anymore. They are taking it. We're proud to present these 10 women who inspire, lead, and rebuild the Biotech industry. To know more about them, kindly scroll through. Also, don't forget to go through the articles written by our in-house editorial team and a piece of CXO advice. Dive in to have a happy read! -Shrutika Khedekar Whenever Suppressed, 'She' Rose! “
  • 6. C O N T E N T S Articles #Closingthegap The Gradual Rise of Women in STEM Fields New Horizons Top Tech Trends Shaping the Biotech Industry 24 38 Mindfully Driving the Revolu on in Women's Healthcare Chia Chia Sun An Ardent Advocate of Digital Transforma on of the Healthcare Industry Maree Beare An Ardent Advocate of AI-driven Drug Discovery Noor Shaker 20 16 34 28 Natalie Bartlett Chauffeur of Modern Change in the Biotech Industry
  • 7. CXO 08 Top 5 trends in Radiology and Imaging 44 Lee Ann Kimak Commi ed to Saving Lives through Exemplary Leadership Cover Story
  • 8. Co-designer Paul Belin Art & Picture Editor Mrunalinee Deshmukh Art & Design Head Editor-in-Chief Sumita Sarkar Managing Editor Abhishaj Sajeev Senior Editor Anish Miller Visualiser David King Rohil Shinganapurkar Circulation Manager Tanaji Research Analyst Eric Smith Sarah Wilson, John Smith, Alex Vincent Business Development Executives Amy Jones Business Development Manager Sales Executives Kelli, Bill, Anna SME-SMO Executives Atul, Gemson Digital Marketing Manager Alina Sege Technical Consultants David, Robert Technical Head Jacob Smile Marketing Manager John Smith Assistant Technical Head Pratiksha Patil Assistant Digital Marketing Manager Amol Wadekar Copyright © 2021 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights success. Reprint rights remain solely with Insights Success Media and Technology Pvt. Ltd. Insights Care is powered by Insights Success Media and Technology Pvt. Ltd. November, 2021 Follow us on : www.facebook.com/InsightsCare/ https://twitter.com/Insightscare Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - 302-319-9947 Email: info@insightscare.com For Subscription: www.insightscare.com Insights Success Media and Technology Pvt. Ltd. Office No. 22, Rainbow Plaza, Shivar Chowk, Pimple Saudagar, Pune, Maharashtra 411017 Phone - India: 7410033802, 74100058552 Email: info@insightscare.com For Subscription: www.insightscare.com Assisting Editors Trishika, Shrutika sales@insightscare.com Corporate Offices:
  • 9. ed or td. Description Featuring Bloody Good Period is now a charity, with a vision to achieve menstrual equity - where the simple fact of bleeding doesn't stop anyone from participating fully in society or life. Company Name Bloody Good Period Glamorous AI Mesa Biotech Gabby Edlin, CEO Noor Shaker, Senior Vice President, and General Manager Vipul Singh, Director and COO 10 Most Admirable Women Leaders in Biotech for 2021 Vor Biopharma is a cell therapy company that combines a novel patient engineering approach with targeted therapies to provide a solution for patients suffering from hematological malignancies. Vor Biopharma Amy Mendel, Chief Legal Officer Korro Bio’s team of experts is working to overcome the challenges that have limited existing gene editing and gene therapy approaches, and treat diseases that have previously been unreachable by other methods. Korro Bio, Inc. Anna Barry, COO Turning Point Therapeutics is a clinical-stage precision oncology company with a pipeline of internally discovered investigational drugs designed to address key limitations of existing cancer therapies. Turning Point Therapeutics, Inc Athena M. Countouriotis, CEO Damiva is the women's health company that makes 100% natural products for women’s health and beauty at any age. Damiva Chia Chia Sun, CEO and Co-founder Bavarian Nordic is a fully integrated vaccine company focused on the development, manufacturing and commercialization of life-saving vaccines. Bavarian Nordic Lee Ann Kimak, US Commercial Lead Wanngi Maree Beare, Founder and CEO Wanngi is a health management app that allows you to track symptoms, immunisations, set medication reminders and manage medical and fitness information, in one secure HIPAA Compliant online location GlamorousAI is bringing drugs to every target though its AI-first SaaS platform for drug discovery, RosalindAI. ZAGENO is on a mission to accelerate scientific innovation by streamlining biotech purchasing processes with its award- winning, first-of-its-kind e-commerce platform. Zageno Natalie Bartlett, Enterprise Business Development Mesa Biotech is a healthcare test and data company that provides actionable information through trusted, PCR-based infectious disease testing—anytime, anywhere.*
  • 10. LEE ANN KIMAK Committed to Saving Lives through Exemplary Leadership “ Our industry is fueled on a constant stream of discovery which requires talented and creative research teams as well as the functions needed to bring new products to market. “ 10 Most Admirable Women Leaders in Biotech for 2021
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  • 12. COVER STORY “Lowering the risk of infectious disease for the greater good of our global community is our main mission. Lee Ann Kimak US Commercial Lead Bavarian Nordic A cruc succ Lea orga may qua rega deci resp We such Wom som ston thro One Kim Lee Com mar prev vacc opp “Ha the and chal incl enri
  • 13. As the business world continues to evolve and disrupt, so does the need for efficient and impactful leadership. As evident as it could be, leadership is crucial to a company’s ascension towards the zeniths of success. Leadership is an integral part of running any successful organisation – large or small. The type of leadership needed may differ depending on what industry you’re in. Still, the qualities of a good leader remain similar regardless—having strong interpersonal skills, being decisive yet open-minded, knowing when to delegate responsibility appropriately, and leading through example. We at Insights Care are on a ceaseless endeavour to seek such impactful leaders. In this edition—10 Most Admirable Women Leaders in Biotech for 2021—we came across some of the most accomplished women who’ve left no stones unturned when it comes to inspiring the world through their journey towards excellence. One prominent name among such leaders is Lee Ann Kimak, the US Commercial Lead at Bavarian Nordic. Lee Ann joined Bavarian Nordic in January 2020 as the US Commercial Lead following the acquisition of two marketed vaccines from GSK. The ability to leverage her previous experience in vaccines and the integration of vaccines into a company made this an interesting opportunity for her. “Having the opportunity to build a US organisation from the beginning—building a team, establishing the processes and infrastructure needed to be successful—was an exciting challenge for me. The company leadership and culture are inclusive, collaborative, and agile, which makes it an enriching working environment,” says Lee Ann. Good business is about hiring good people; without them, it is hard to grow and sustain momentum over time. “ Setting Benchmarks Bavarian Nordic is a fully integrated vaccines company focused on developing, manufacturing, and commercialising life-saving vaccines. The company’s fundamental mission is to save and improve lives by unlocking the immune system’s power. “We have established a bold vision and aspiration to become one of the largest pure-play vaccine companies by 2025,” says Lee Ann. Bavarian Nordic has a strong heritage in vaccine research and development and proven successful technology. Innovation remains a cornerstone in developing a strong product pipeline to help fight existing and emerging diseases around the globe. Overcoming Adversities We asked Lee Ann about the challenges that the COVID-19 pandemic imposed on the global biotech industry and Bavarian Nordic and how she and her team pivoted to surpass those challenges. Her response: The pandemic has spurred global leadership to look to biotechnology and pharmaceutical companies for solutions to the pandemic, including diagnostics, assays, therapeutics, and vaccines. Our industry is uniquely suited for this task as we have invested in scientific acumen and the regulatory, clinical, and manufacturing capabilities to deliver these needed solutions. “The global COVID-19 pandemic did, unfortunately, impact many parts of our business. However, a highlight earlier this year is that Bavarian Nordic reported encouraging preclinical data for a COVID-19 vaccine candidate ahead of first-in-human trials.”
  • 14. “The pandemic also caused business challenges to collaboration, hiring and of course travel and interactions with customers. Bavarian Nordic took complete care to assure that appropriate precautionary measures are in place and consistent communication and check-ins with our team members occur.” “Our top priority is the safety and wellbeing of our team members, customers, and communities we serve. We immediately moved to remote working, and like many companies, became accomplished at leveraging team platforms to collaborate, hire talent, and interact with customers. Several working groups across the globe were formed to evaluate areas of business, including the outlook for our future workplaces and more flexible ways of working,” Lee Ann added. Opinions that Matter We asked Lee Ann for her opinion on the necessity for biotech companies to align their offerings with newer technological developments, which she answered saying, “As I mentioned before, Bavarian Nordic has a strong heritage in vaccine research and development, and with a proven technology, innovation remains a cornerstone in the development of a strong product pipeline to help fight existing and emerging diseases around the globe.” “We are experts in live virus vaccine manufacturing, and with the recent addition of fill and finish capabilities, we have enabled end-to-end commercial-scale manufacturing. Lowering the risk of infectious disease for the greater good of our global community is our main mission,” she expressed. Sharing her opinion on the probable future of the biotech sector post the pandemic, Lee Ann says, “Our industry is fuelled on a constant stream of discovery which requires talented and creative research teams as well as the functions needed to bring new products to market. Our organisation is learning how to identify the most creative and talented teams to focus on bringing innovative products to market, like an RSV vaccine and COVID booster. When you give a great team the job of working on these life-saving products and the tools to do it, they can change the world! You’re doing something useful for society, which is an incredible thing.” A Necessary Change When asked, what would be things she would change about the global biotech industry, Lee Ann expressed, “The pandemic spurred intense government, media, and public attention on biotech. Maintaining a high level of innovation and development is critical to the success of our industry, but we also need to have highly skilled talent in other areas beyond discovery and development.” “We need to focus on building and retaining good talent, managing complexity, and improving commercial and development execution. Bringing good products and vaccines to approval is only part of the process. We need to make sure that we are doing the market development and otherwise providing the commercial support to assure that valuable products are accessible to the patients who can benefit from them.” Bequeathing the Keys to Excellence As an excerpt from her professional journey, Lee Ann shares valuable advice to those aspiring to venture into the Biotechnology space, saying, “Don’t give up easily is one piece of advice. Working in small or start-up biotech’s can be challenging, and there is a new problem to be solved every day. Resilience needs to be developed as well as a willingness to operate with a high level of ambiguity and not a lot of processes.” “We have established a bold vision and aspiration to become one of the largest pure-play vaccine companies by 2025. Voy Talk ope Bav vacc mar year dise RSV “Go it is goa outs effe for t con
  • 15. n is t, e a cts e out c ion y, eas to d at he e an d Voyaging towards New Horizons Talking about her vision for scaling Bavarian Nordic’s operations and competency, Lee Ann says, “Currently, Bavarian Nordic’s RabAvert is the market leader in rabies vaccination, and we look forward to adding additional market-leading products to our portfolio in the coming years. We have multiple product candidates for infectious diseases and cancer, including candidates for COVID and RSV, which are large scale programs.” “Good business is about hiring good people; without them, it is hard to grow and sustain momentum over time. My goal is to build on our existing team by adding more outstanding talent that can make sure we effectively deliver these products to the market for the patients who need them,” Lee Ann concludes.
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  • 17. Stay in touch. Subscribe to Insightscare Get Insightssuccess Magazine in print, & digital on www.insightscare.com Check should be drawn in favor of : INSIGHTS SUCCESS MEDIA TECH LLC
  • 18. Chia Chia Sun Mindfully Driving the Revolution in Women’s Healthcare Chia Chia Sun CEO and Co-founder Our mission is to develop products that are helping, not harming, women with a focus on prevention. 16|November 2021|www.insightscare.com M indi hav in th igno and ove abo the One peo wom is C foun In th Sun the face pan firm Giv jour tell into Abo peri - I r didn futu the of k wom our I sta drug vag ther to u con toxi natu Dam incl who train real exis
  • 19. s Modern science and the perseverance and contribution of several individuals towards women’s health have made some significant discoveries in the sector. The negligence and ignorance regarding women’s health and wellness are now being slowly overcome as people have begun to talk about it and break the stigma around the topic. One prominent name on the list of people striving relentlessly to improve women’s health by leveraging science is Chia Chia Sun, the CEO and Co- founder of Damiva Inc. In the following interview, Chia Chia Sun talks about her inspiring journey in the women’s health arena, how she faced the challenges arising from the pandemic and the prospects of her firm. Give us a brief overview of your journey as the CEO of Damiva and tell us what inspired you to venture into the women's health space. About ten years ago, when I was perimenopausal - I'm menopausal now - I realized that there was so much I didn't know about myself and my future menopause. I was stunned by the lack of information - and my lack of knowledge - about the stages of a woman's life, our hormonal fluxes, and our bodily changes. I started Damiva after a trip to the drugstore, looking for a product for vaginal dryness. What I found was that there was absolutely nothing I wanted to use because all the products contained so many chemicals and toxins. After formulating a 100% natural product - called Mae by Damiva - with several partners, including my husband Gardiner Smith, who is a protein chemist and lawyer by training, and a couple of stints on reality TV shows, Damiva came into existence. It became my passion and life mission to develop products for women that are good for us for a lifetime, and we can use them at any age. I decided that, due to the dire unmet need, I would only work in women's health for the rest of my career. Tell us more about Damiva, its vision, and the key aspects of its expertise in health and wellness. The core vision for Damiva is to create products that are good for women. To us, this means 100% natural feminine care and skincare products that are pH balanced for each stage of life and - as a priority - do not contain any chemicals that are toxic, disrupt hormones, and contribute to the climate crisis. Creating an all-natural, shelf-stable product is much harder than you might imagine (think Buzzfeed's Burger Experiment). So, we have proprietary formulations and patents that speak the unique nature of our health and wellness products. For example, by removing water from our formulations, we don't need to use chemical preservatives and can still maintain a shelf life of three to five years without bacterial growth. From a leadership perspective, what is your opinion on the impact of the pandemic on the global healthcare sector, and how did you aid your organization to overcome the challenges rooting from the pandemic? The pandemic focused a lot of attention on the global healthcare sector and helped create more awareness of the need for health care innovation. On the plus side, there is more capital and consumer acceptance and adoption of new health technologies. On the downside, larger companies benefited from the massive shift in public opinion and government funding more than smaller companies. Our retail revenues were impacted by COVID-19 due to the drop in-store traffic by our retailers such as CVS, Target, and Rite-Aid. We were already expanding our online sales, and we put much more effort into the endeavor as the pandemic unfolded. We realized immediately that the pandemic gave us an opportunity to connect much more closely with our customers, and the learnings have significantly impacted our business and improved our product development. What is your opinion on the necessity for health and wellness companies to align their offerings with newer technological developments, especially when it comes to catering to the ever- evolving needs of the industry? A significant lesson from our expansion of online sales was that our customer is highly sensitive, not just to toxic chemicals in formulations but also to the changing world around us, including technology, information, and macroeconomic factors such as climate change. Our philosophy at Damiva is to listen to our customers and their needs. Accordingly, we packaged our next-generation products in discrete sachets (instead of a large bottle), reducing our packaging footprint by over 50%. We also developed a customer-centric educational membership program that is entirely online and geared to specific life stages. Regarding the alignment of health and wellness companies with advances in technology, while I'm personally invested in innovation, as the co-inventor on several patents, I believe that the field of women's health needs more than innovation; it needs innovation communication. 10 Most Admirable Women Leaders in Biotech for 2021 17|November 2021|www.insightscare.com
  • 20. We need to try harder to understand women's needs, even if these conversations are awkward or uncomfortable. We need to break down the taboos that prevent women from expressing their needs. Vera Rubin, who is one of my heroines and should have won the Nobel Prize for Physics as the physicist who discovered dark matter, said it best when she said, "Don't shoot for the stars; we already know what's there. Shoot for the space in between because that's where the real mystery lies." What efforts did you and your team at Damiva take during the pandemic to sustain operations and ensure the safety of your employees at the same time? Our team is in Canada, the United States, Europe, and India. While we were accustomed to virtual business already, we made the switch from working exclusively in our Toronto offices to the entire staff working virtually from home during the pandemic. In your opinion, what could be the future of the women's health space post the pandemic? And how are you strategizing Dative’s operations for that future? Women are already the ‘Chief Medical Officers’ of our households as 80% of us make the medical decisions for our families. The women's health space is already changing post-pandemic as households are increasingly accustomed to at-home testing, diagnostics, and preventive medicine, with women leading the charge. The new norm will continue to be more technology, less travel, and more local support for women's well-being. The cons of a post-pandemic era for women's health are that, while women took on more of a role at home with respect to childcare, children's schooling, and family health, areas such as career growth and mental health have suffered. To remedy this, we women need to spend some time putting ourselves and our health first. At Damiva, our future operations post- pandemic will focus on prevention, self-care, and the use of technology to deliver highly informative and specialized content. Our mission is to develop products that are helping, not harming, women with a focus on prevention. As our products are completely natural and pH balanced, they help preserve the skin microbiome and include preventive ingredients such as probiotics that are stable at room temperature. With respect to self-care, our strategy for 2022 and beyond is to continue to have fun with our products while creating a supportive environment with our online content membership program. For example, we will always have cheeky slogans such as "lip balm for your other lips" for our labial balm. Now, we will help women understand the different parts of the labia and genital regions and how they change over time. In response to inquiries from health professionals, we have also started a collaborative Professional Program to work with pelvic health experts, such as menopause practitioners, nurses, physicians, and physiotherapists, to educate women about our products. If given a chance, what is the one thing that you would change about the global healthcare industry? I would change the ratio of male to female leaders in the industry. Depending on the area, female CEOs comprise 3% to 6% of the total number, and this is an appalling statistic. To quote Vera Rubin again, "Worldwide, half of all brains are in women," and another great quote: "We all need permission to do science, but for reasons that are deeply ingrained in history, this permission is more often given to men than to women." As an established leader, what would be your advice to the budding entrepreneurs aspiring to venture into the women's health space? Just go for it! Feet first, as fast as you can. We need many more women to expand this important industry that affects half the human race. Pertaining to your role as Damiva's CEO, how do you envision scaling your company's operations and offerings in 2022 and beyond? One of the major initiatives we put into place during the pandemic was to redesign our packaging to withstand a variety of extreme temperatures that we are experiencing with global warming and climate change. This redesign will enable us to grow quickly and scale our operations in North America and beyond. We are partnering at home here in the U.S. with our manufacturer to be the largest 100% natural women's health company globally. First and foremost, as always, our offerings continue to put women first by giving women what we need and want: completely natural, vegan, ethical, and sustainable products that are free of hormone disruptors and toxins. 18|November 2021|www.insightscare.com
  • 22. Maree Beare An Ardent Advocate of Digital Transformation of the Healthcare Industry Founder and CEO 20|November 2021|www.insightscare.com M heal scre hav and this adv tech imp for h wor The pati the plat plat The man man plat Ma entr Wa com Mar Hea has wom Hea inno glob exec proj gov brin and heal sect The Clin In 2 she con thei acce
  • 23. e of ry Modern hospitals and clinical institutions have become increasingly reliant on healthcare software systems. Touch screens, tablets, and internet reports have quickly replaced paper-based files and written patient information. All of this has been made possible by huge advances in the realms of information technology. Technological improvements have made life easier for hospital administrators around the world. The requirement for a comprehensive patient information system spawned the concept of healthcare management platforms. The primary focus of these platforms is managing patient records. The demand for healthcare management solution is attracting many entrepreneurs to develop such platforms. To cater to this demand, Maree Baeree an enthusiastic entrepreneur established her companies Wanngi and Clinials, to track and communicate the health of people. Maree Beare is a sector leader in HealthTech, Femtech, and Biotech, and has been listed by Forbes in the top 50 women-led startups disrupting Healthtech. She has over 30 years innovation experience, navigating global software companies and executed many large and high-profile projects to meet company and government strategy. Maree now brings this leadership to the Startup and Innovation sector and the healthtech, femtech, and biotechnology sectors globally. The Inception Story of Wanngi and Clinials In 2017, Maree created Wanngi when she realized that it was a problem for consumers to make decisions about their own health when they had no access to their own health data. “I imagined a world where people could improve their chances of being diagnosed by providing their health history to the various doctors and hospitals they might see during their life,” says Maree. Maree is of the opinion that hospitals and doctor’s health systems are not connected, resulting in people having to repeat their health history over and over at each health appointment leading to miscommunication and misdiagnosis. Fast forward to 2020, Maree’s husband went on a clinical trial and was required to report any adverse events by completing a paper form. Opening Maree’s eyes to the issues with participating on clinical trials where lifesaving treatments are not making it to market as 80% research trials fail to find enough people. In 2021, Maree launched Clinials, providing efficiencies in the $47 Billion clinical trials market by disrupting the existing study participant recruitment process, so people are getting access to more effective treatment sooner. “We aim to Enhance patent recruitment per clinical trial to improve site economics for clinical trials leading to Improved treatment and patient outcomes and for many, this means improving life quality (QALY),” shared Maree. Braving the Pandemic During the outbreak of the COVID-19 pandemic, Maree and her team switched to working from home and returned to the office only when officials allowed. Maree believes that the pandemic has sped up innovation in healthcare due to the dire necessity. It led to the increased use of telehealth for safety and convenience of continued care. I imagine a world where people could improve their chances of being diagnosed by providing their health history to the various doctors and hospitals they might see during their life. 10 Most Admirable Women Leaders in Biotech for 2021 21|November 2021|www.insightscare.com
  • 24. The pandemic has escalated the need for decisions around a person’s health status and the requirement for access to COVID-19 test results and vaccination status. There’s a great deal of noise and uncertainty about accessing this data for consumers. However, Wanngi is fit for purpose as a consumer personal health record, so it was ready and able to store and provide evidence of COVID-19 tests and continues to help people provide their health history during a telehealth appointment. However, with the focus on COVID- 19, the health management of people with chronic illness declines and the aftermath of pandemic will see a burden of late-stage chronic illness on the healthcare system. Clinials will provide the platform to connect these patients to any clinical trial relevant to their health conditions, where they meet the inclusions and exclusions of the study. Leveraging Technology When asked for her opinion on the importance of technology in the healthcare industry, Maree says, “Companies seek to be economically sustainable, and healthcare is no exception. Technology will drive efficiencies in healthcare as well as improving patient outcomes with AI and innovation, and in the future, it will continue to develop in dramatic ways.” “While we can take a glimpse and debate the details of future trends in healthcare, we need to be clear about the drivers so we can align with them and actively work to ensure the best outcomes for society as a whole,” adds Maree. Maree aspires to overthrow the misconception that investment cycles in healthcare are the same as traditional investments. “History tells us that it takes 10 years to be an overnight success in Healthtech,” she added. Envisaging Future Endeavors Clinials is uniquely positioned to secure product led growth moving forward into 2022 and beyond. Having raised pre-seed funding in 2021 and preparing for a larger raise in early 2022, the company is ready to expand the team to support its customers. It is focused on building the innovation roadmap to decrease cost of trial marketing, recruitment and leveraging Machine learning and AI to accelerate product-led growth and continue Clinials customer retention. “I have already delivered on the future strategy by launching Clinials this year in response to the opportunities of Australia being relatively COVID-19 free, and there being a verified problem to solve with participant recruitment in clinical trials to enable Australia to be globally competitive in research of new treatments,” concludes Maree. 22|November 2021|www.insightscare.com
  • 27. Gradual Rise Women The of in STEM Fields STEM Fields #Closingthegap Science, technology, engineering, and mathematics (STEM) fields are significantly important to power innovative advancements and enhance technological developments. These are the factors that in turn are seen as drivers of social and economical growth. As a result, researchers and policymakers are paying substantial attention to analyse and promote high-growth ventures in STEM fields. The consistent analysis has resulted in making STEM a valuable part of education in universities and also in the accommodation of jobs in developing countries. As every coin has two sides, one of the major criticisms of STEM has to do with the gender disparity in students who graduate with STEM degrees and enter career mainstreams related to these fields. Research data has conventionally displayed that 'women are far less likely to graduate with a STEM degree or enter a mainstream career in this field,' when compared to their male opposite number. Vanquishing a Gender Gap Proponents of closing this gender gap in the STEM field points out that this gap not only reflects unfair conditions and poor treatment of women in this field. Furthermore, it also reduces the quality of work and innovations being extracted from these fields. It is a subject of recommendation and facts that indicate scientific progress relies on unique solutions that are emerging from different perspectives. Closing the gender gap make STEM fields more diverse, also, redefines the assurance of problem-solving approaches with a variety of different perspectives. Although the broad gender gap that exists across the STEM fields becomes a topic of discussion, there is a great deal of variety among different STEM subfields when it comes to the exact scale and nature of this gap. Some subfields have no gap at all and favour women in graduation, and job placement. In subjects like social science, there is a greater number of women if compared to men, and it remains strongly favourable towards women. 25|November 2021|www.insightscare.com
  • 28. Enabling Innovations It is a fact of assurance that women would benefit from the creation of more inclusive atmospheres in STEM fields, these fields as a whole can become more engaging. A field like science works and functions at its best when it considers a wide range of diverse perspectives. By excluding women, such fields not only exclude a wide range of extremely talented future leaders but also fresh perspectives that could be used to create innovative approaches to resolve problems. Engaging women in stem fields has improved the quality of work being executed in those fields and it has opened up distinguished career opportunities for women. In general, research has displayed that, 'diverse workplaces are happier in nature and more productive,' indicating that STEM organizations could do better for themselves by being more inclusive. Breaking the Stereotypes The idea of the gender equality paradox is not without its problems. Critics point out that countries with poor representation in STEM fields have a long history of excluding women from science and mathematics, which has been deeply embedded into the culture that surrounds young girls as they are growing up. They also point out that there is no gap in ability since researchers found that girls performed as well or better than boys on STEM tests in most countries. True solutions to the gender gap in STEM fields work on multiple levels. Exclusion begins in childhood, when young girls have been pushed away from creative fields like science, and mathematics, and are encouraged to adopt more care-oriented work. This scenario is drastically changing as parents are encouraging and reminding their children that they can grow up to do anything that they want. Parents are also providing a wide range of opportunities for children to explore their interests, including those related to STEM, such as coding camps and science fairs. In education, scholarships and grants are striving hard to bring women into STEM departments. However, these departments must do everything in their power to prevent discrimination and sexism against female students to improve preservation rates. In the workplace, employees must identify and address the discrimination in their hiring practices so they can generate a diverse workplace that enhances productivity among their employees. Outside of school and the workplace, broader societal changes are also called for. Women are often harder hit by a couple's decision to raise a family, forcing them to take more time off of work during critical periods in their careers, such as early on at a new job or even during their doctoral studies. Despite these situations, women are making noteworthy progress not only in STEM fields, but also in their profession, and are breaking the stereotypes. The Profound Leaders in STEM Many women have made significant contributions to our understanding of the world and these contributions are now being recognized as an example for the young generation. Below are just a few of the women who have changed the world with their knowledge and expertise in STEM fields. Ada Lovelace Ada was one of the early computer scientists. Her work was instrumental to the advancements of early computer science as she developed an algorithm for Charles Baggage's analytical engine that would output Bernoulli numbers. Marie Curie Marie Curie is recognized as the most inspirational female scientist of all time. She was the first person to win the Noble Price twice in her career. Marie's work involved radioactivity, including the discovery of a few radioactive elements. Rosalind Franklin Rosalind was an English chemist whose work on molecular structures established a foundation of our comprehension of the fundamental workings of things like DNA, RNA, and viruses. Sally Ride Sally Ride was an astronaut, engineer, and physicist. Sally's position as the first American female astronaut and the third woman to travel into space, as well as her science books aimed at children, have created the legacy of an inspirational figure for many young women and girls interested in STEM fields. The Journey Ahead... Although increasing comprehensiveness for women in STEM has recently become a trending topic, women have been making waves in STEM fields since humans began to examine the natural world. One way to bolster the ranks of future women in STEM is to acknowledge the contributions women have made in the subfields of STEM in the past. - Abhishek Joshi 26|November 2021|www.insightscare.com
  • 30. Natalie Bartlett Chauffeur of Modern Change in the Biotech Industry Pharma R&D is one of the most booming industries that always supported the world even when the pandemic hit it; thanks to its bloodline, the leaders of lab supply chain companies have always kept it running. In the last few years, the biotechnology industry has witnessed digitalization and enhancement of technology in its every code of conduct as people are looking for an advanced way of coxswaining everything. The demand for digitalization in the biotechnology supply sector is very 28|November 2021|www.insightscare.com Natalie Bartle Enterprise Business Development high sam lab tele look To f biot prom Ent of Z solv com incl com alte mak extr elim Bar clie dev In th us a saile clie Foll inte Giv jour ZAG insp biot I sta focu life in a was inte Cata ZAG scie focu I fou outd supp tech
  • 31. t ed e high as many are still following the same outdated method of purchasing lab supplies with catalogs, fax, telephones, and so on, and buyers are looking for a better alternative. To fulfill this need of the biotechnology industry, one of the prominent leaders Natalie Bartlett, the Enterprise Business Development of ZAGENO, has worked very hard to solve many issues through the company's in-depth solutions. These include online monthly spending data, comparison of products, best alternatives, tracking order status, etc., making the industry's procedures extremely convenient. Also, by eliminating various steps, Natalie Bartlett has given her best to save her client's time and money potential by developing the company's top services. In the following interview, Natalie tells us about the various challenges she sailed through to provide ZAGENO's clients with excellent services. Following are the highlights of the interview: Give us a brief overview of your journey through your role at ZAGENO, and also tell us what inspired you to venture into the biotechnology sector. I started working in venture capital and focused on early-stage startups within life sciences and software. Growing up in a family of healthcare providers, this was a good fit because I always had an interest in the space. While at General Catalyst, I sourced and invested in ZAGENO, a startup reimagining life sciences commerce with an initial focus on R&D supplies. I found myself intrigued by how outdated purchasing products for lab supplies was and how a team and technology like ZAGENO's could help solve this. I decided to roll up my sleeves and help make a direct impact on myself. Today, I work on ZAGENO's enterprise business development team, focusing on helping large pharma organizations improve their research efficiency when ordering supplies. Tell us more about ZAGENO, its vision, and the key aspects of its stronghold in the global biotechnology space. ZAGENO's vision is to accelerate the time between scientific milestones. While simple to articulate, it is quite complex in executing this vision. It begins by completely rethinking the industry's lifecycle, which begins with identifying where other business markets have successfully transformed, modernized, and automated. We sometimes take the kernel of other innovations and customize them for biotechnology. Our interpretation of the well- established subscriber model is experienced through ZAGENO's marketplace and services. Through it, our subscribers benefit from various unique advantages such as data on historical spending, detailed product comparisons, and alternatives to products on backorder or with long lead times. At a high level, ZAGENO seeks to democratize the buyer-seller relationship through lab supplies - the very lifeblood of scientific discovery. Historically, this part of the industry was dictated by manufacturers and distributors. Without an alternative, scientists had little choice but to accept this status quo. But just as the subscription economy has redefined the buyer-seller relationship in consumer markets, so is it changing these relationships in biotechnology. The future of the industry will be a more harmonious one, equally dictated by manufacturers and users. Because ZAGENO provides a platform to support this evolution, we are at the epicenter of this change. From the business development perspective, what is your opinion on the impact of the pandemic on the biotech space? How did you aid your organization to overcome the challenges rooting from the pandemic? From ZAGENO's perspective, the pandemic has divided the industry into groups of haves and have nots. The thing that is often overlooked is the running cost of biotech, which can range from $10,000-40,000 per day. So, any downtime in productivity can have profound business implications to the bottom line. COVID's impact on the supply chain caused some labs to go dark and their scientists to be furloughed. But biotechs that subscribe to ZAGENO benefit from access to a marketplace 10 Most Admirable Women Leader in Biotech for 2021 29|November 2021|www.insightscare.com .
  • 32. where they are able to forecast accurately and manage supply levels and face challenges like backorders and extended lead times with suitable alternatives to ensure labs remain open and productive. What is your opinion on the necessity for biotech companies to align their offerings with newer technological developments, especially when catering to the ever- evolving healthcare needs? While focusing on investing in early- stage startups at the intersection of life sciences and software at General Catalyst, I witnessed the burgeoning of startups looking to accelerate the drug discovery process from R&D through clinical and beyond. In my opinion, the software has not impacted the life sciences field in the same way it has in other industries, so the opportunity to accelerate the drug discovery process (which today averages ten years) through the use of the software is immense. For R&D purchasing in particular (ZAGENO's focus), a vast majority of research scientists are still purchasing supplies in the same way consumers purchased goods in the 1970s! They are still phoning and faxing in orders via paper catalogs. While today's consumers can buy groceries in one click and have them arrive the same day, scientists spend 4-8 hours just finding and purchasing supplies. If technology can reduce wait times from weeks to days and even hours, imagine the savings potential, both in time and money, of the drug development process at large! Through your role as Enterprise Business Development, what efforts did you and your team at ZAGENO take during the pandemic to sustain operations and ensure the safety of your employees at the same time? As you may imagine, the demand for R&D supplies during COVID has been immense. As our team transitioned to a work-from-home setup, our order volume simultaneously skyrocketed. Personally speaking, I cannot imagine starting a new role or even a first job completely remote! But with half of ZAGENO based in Berlin, we were already accustomed to remote collaboration through video meetings, slack, and other web-based tools. To further support a work-from-home environment, our team also focused on several initiatives, such as new daily and weekly stand-up meetings. We also provided our leadership with resources for remote management and guidelines for remote work to all employees. To provide additional support for new employees, we established a buddy system so that new hires had a dedicated ZAGENO alum as a resource. For all employees, ZAGENO also sent care packages to ensure everyone had proper at-home office and technology setups. Despite a majority of ZAGENO never having met one another, as a company, we have been quite productive, which is evidenced by a doubling in revenue over the past year. In your opinion, what could be the future of the biotech sector post the pandemic? And how are you strategizing your organization's operations for that future? 30|November 2021|www.insightscare.com We the whi futu Afte labs beg spli perf man It be supp scie the in p that long even ZAG to e mob into Mea cust to su they
  • 33. gs, o on y th nd new m o e ver ny, ch ue e he We have witnessed a few trends during the pandemic for remote lab work, which I believe will continue in the future. After the initial closure of research labs, we saw that research scientists began to return for critical work only, splitting into teams to reduce risk and performing all operational management remotely. It became even more critical that supplies were there for research scientists when they did spend time in the lab, especially amidst an increase in product backorder rates. I believe that remote lab management will be a long-lasting effect of the pandemic, even beyond just ordering supplies. ZAGENO is strategizing its operations to enhance these capabilities through mobile optimization and integration into inventory management solutions. Meanwhile, our operations and customer success teams are equipped to support research scientists whether they are at the bench or at home. As an established leader, what would be your advice to the entrepreneurs aspiring to venture into the biotech space? For entrepreneurs looking to build software companies in the life sciences space, in particular, my biggest advice would be to create a well-rounded team with experience from both the life sciences and software industries. Given that startups in this space are still emerging identifying and hiring individuals with blended expertise is quite challenging. However, there is unique knowledge from both sides that needs to be combined in order to build a successful company, so instilling this balance through your team from the start as well as while you grow is essential. How do you envision contributing towards the goal of sustaining your company's stronghold in 2021? I have recently taken on a role in enterprise business development, with a particular focus on enhancing their purchasing experience for the industry's largest pharmaceutical companies. In this time, I've witnessed the huge trend happening across pharma R&D to provide a superior user experience, consolidate buying channels, and drive digital adoption for both time savings for research scientists and cost savings for the research team at large. Building supply and demand are crucial to winning the market with any new subscriber service (e.g., a marketplace). I believe that working with large pharma will not only drive our stronghold within the market to realize our company's full potential but will also simultaneously bring efficiency to the lengthy R&D drug development process. It's a true win- win, which aligns with ZAGENO's greater mission to accelerate life sciences. 31|November 2021|www.insightscare.com
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  • 36. Noor Shaker, Senior Vice President, and General Manager Our focus on hiring self-motivated, highly productive individuals has certainly helped us scale while sustaining healthy growth. 34|November 2021|www.insightscare.com A inte proc proc effic dev com iden AI a savi cata imp go-t who Wh the Sen Gla In a jour of A Noo you you
  • 37. Noor Amidst the ongoing pandemic, AI-driven drug discovery has been at the forefront of the healthcare sector, consisting of molecular features, interactions, and behavior in order to build better materials, processes, and systems for specific purposes. Traditional processes require clinical trials on patients to investigate the efficacy and optimum combination of drugs or dosage in developing viable therapies. But an AI-based drug combination therapy is proving to be a critical technique for identifying optimum and effective regimens. AI accelerates the drug development process along with saving time, money, and human efforts. In short, it is a catalyst that speeds up drug discovery. Hence, the implementation of AI in the healthcare space has become a go-to option for pharmaceutical companies and their leaders who are aspiring to dominate the drug discovery market. While many such health leaders are charting strategies for the healthcare sector, we came across Noor Shaker, the Senior Vice President and General Manager of GlamorousAI, who chose to take the unbeaten path. In an interview with Insights Care, Noor sheds light on the journey of her company, its services, and how the adoption of AI is transforming the healthcare sector. Noor, give us a brief overview of your journey through your role at GlamorousAI and also tell us what inspired you to venture into the biotechnology sector. My journey started as a computer science engineer in my home country, Syria. I got fascinated by Artificial Intelligence early on, and I realized that the field would have a great impact on so many aspects of our lives. I, therefore, decided to pursue a career in AI, and that led to my assistant professorship in AI from the Aalborg University of Copenhagen. The time at which I got my assistant professorship coincided with the heartbreaking passing of my mother after a long fight with lung cancer. Shortly after, I decided to drop my academic position and focus on the translation of AI research to the drug discovery space. I co-founded Glamorous AI in 2020 to deliver on my mission to cure diseases with the power of AI. Tell us more about GlamorousAI, its vision, and the key aspects of its stronghold in the global biotechnology space. GlamorousAI’s vision is to bring drugs to every disease. We are doing this through innovative AI solutions that are data-efficient and through putting these tools in the hands of drug hunters. Our AI allows us to extract information and patterns about the disease and potential drugs from challenging datasets. This is a key in biomedical research where data is usually noisy, unbalanced, and small. We’ve recently joined forces with X-Chem, a leading service provider in the Shaker An Ardent Advocate of AI-driven Drug Discovery 10 Most Admirable Women Leaders in Biotech for 2021 35|November 2021|www.insightscare.com
  • 38. DNA-Encoded Library space, and we believe that together, we can bring AI, data, and expertise under one roof to provide the best services to the pharmaceutical industry. What is your opinion on the impact of the pandemic on the biotech space, and how did you aid your organization to overcome the challenges rooting from the pandemic? I think the pandemic had a positive impact on the biotech sector; it certainly increased the public awareness of the field and the difficulties associated with the discovery of new medicines. Glamorous AI’s inception was just after COVID-19 hit, and that meant that we had to build a remote working environment and culture from the get-go. That has actually helped us build a global hiring strategy and tap into the international talent market. What is your opinion on the necessity for biotech companies to align their offerings with newer technological developments, especially when it comes to catering to the ever-evolving healthcare needs? I think the biotech industry needs to keep up with the fast pace of innovation to ensure the best outcomes for patients. Startups and small businesses in this sector are leading the way with innovative solutions that will soon become the mainstream to how we discover and treat patients. Through your role as SVP and General Manager, what efforts did you and your team at GlamorousAI take during the pandemic to sustain operations and ensure the safety of your employees at the same time? We have a great multidisciplinary team of international experts located in different geographies. We have been hiring for remote positions since the company’s inception, and that meant that we needed to put processes in place to ensure clear communication and a healthy, scalable culture. Our focus on hiring self-motivated, highly productive individuals has certainly helped us scale while sustaining healthy growth. In your opinion, what could be the future of the biotech sector post the pandemic? And how are you strategizing your organization’s operations for that future? It became evident just over the past year, or so that AI will play a big role in how we develop new cures. AI innovation and adoption in the biotech sector are set to increase over the next few years. I believe success in this sector will be led by organizations who understand the multidisciplinary nature of innovation required and, therefore, the need to build cohesive multidisciplinary teams. I’m also a believer in open innovation and that AI tools and advancements should be integrated with every drug discovery program. We are therefore focused on not only building best-in-class AI but also on democratizing access to our AI solutions through our SaaS platform, RosalindAI. As an established leader, what would be your advice to the entrepreneurs aspiring to venture into the biotech space? Personally, I find the biotech sector one of the most, if not the most, exciting fields to be in. It combines the social drive of improving human lives with the intellectual cursory necessary to find innovative ways to advance science. How do you envision scaling your company’s operations and offerings in 2022 and beyond? We are looking to enable every drug hunter with the best- in-class AI solutions to drive the discovery of more effective medicines. To deliver on this, we are hiring the best talent and expanding our customer base to enable the democratization of AI in drug discovery. 36|November 2021|www.insightscare.com
  • 40. Biotech Industry Tech Trends Shaping the Top iotech Innovations: Casting a new net B Pandemic brought Biotech from the shadows to the limelight. The industry which was earlier catering mostly to medicine, biopharma, and healthcare, is now opening for consumers of Biotech and customers of Biotech. They have already been re-casted by scaleups and start-ups in developing repurposed drugs, rapid testing kits and vaccines. US remains the main Biotech Innovator worldwide. And US is again casting a new net of Biotech Innovation, with huge investment pouring in from both public and private sources. Biotech Trends: Shaping an Industry The novel innovative threads (read trends) of this net are, #AI (Artificial Intelligence): Start-ups are using Automation for discovering the treasure of new drugs, products, and processes and screening biomarkers. They are also using Image classification algorithm to detect different 38|November 2021|www.insightscare.com trait canc Furt anal leve plat Wh anal a tra
  • 41. h , are ent traits (like crop disease symptoms from leaf images and cancer cells from medical scans) quickly. Furthermore, start-ups are developing rapid diagnostics, analyzing microbiomes, and screening phenotypes by leveraging deep learning. Firms are also developing RNA platform which are guiding therapeutic development. While others are identifying genetic markers which analyzes genomic data to understand genetic mechanism of a trait and then developing applications for novel drug 39|November 2021|www.insightscare.com
  • 42. design, plant and livestock breeding, and diagnostic development. #Big Data and Analytics: This solution is enabling start- ups to tap into ever growing wealth of data coming in from omics tech, sensors integration, and IoT (Internet of Things) devices. This allows such firms to recruit patients and perform clinical trials on them more effectively. It can further find out suitable and safer treatment regimens as well as develop such regimens from disparate and unstructured data sources. They can also deploy such solutions to develop better feed, explore yet undiscovered microbes and improve varieties of crop and livestock. Firms have developed a platform of genomic data analytics, by using a data library, to manage all data, samples, and modules, and run bioinformatic pipelines via cloud computing. #Gene Editing: Today instead of genetically modifying organisms, gene editing can precisely and efficiently edit genome, leveraging developments in CRISPR (as molecular scissors), and engineered nucleases to treat genetic disorders by editing (adding, replacing, and/or silencing) that gene. This can also create genome edited and transgenic plants, and animals. There is also a next generation delivery tech, where chloroplast engineered traits are integrated into breeding processes suitable for engineering of metabolic pathways and modification of photosynthetic pathways. #Precision Medicine: Biotech start-ups are leveraging this solution to discover new drugs, identify novel targets, develop new drug delivery tech, and offer gene therapies. There are also patient-centric, AI-powered gene therapies and drug development programs for non-invasive, precise, and personalized drug delivery mechanisms and gene therapy vectors. #Gene Sequencing: The reduced cost of gene sequencing has opened a wide range of applications like large cohort setups with extensive phenotyping, identification of pediatric disorders, personalized treatments, detecting microbes' presence (pathogens in clinical, beneficial soil microbes). By using defined input sequences, start-ups are providing a solution for the quick and accurate identification of active COVID-19 infections. #Biomanufacturing: Utilizing biological systems it produces medical products and therapies, food and beverages, biomaterials, and specialty chemicals. To make it inexpensive and scalable, startups are advancing recombinant production technologies, fermentation, and different cell culture. The sustainability is enhanced by using biological raw materials. The industry's production models are also adopting machine learning and automation. Integrating Industry 4.0 models of automation and machine learning, startups are offering bioprocessing 4.0 to optimize each stage of the production process. #Bioprinting: By utilizing bioprinters which work with bio-inks developed from bio-based and biomaterials extracted from patients own cells, start-ups are enabling skin, bone, personalized medicines, and vascular grafts development. #Synthetic Biology: It offers increased standardization and reproducibility, allowing organisms manipulation at the gene networks level. A high yield of valuable biochemicals is provided by bacterial cell factories with applications in food, pharma, and materials. Moving beyond microbes, mammalian synthetic biology solutions are also in development. #Microfluidics: LOC or lab-on-a-chip devices needs microfluidics. These miniature labs facilitate POC or point- of-care diagnostics, quick and inexpensive testing of infectious diseases. For diagnostics and environmental monitoring, start-ups are also developing paper-based microfluidics. The tech finds more biopharma applications in OOC or organ-on-a-chip devices, which simulate the physiology of organs/organ types on little chips. OOC systems are useful in disease modeling and drug screening. #Tissue Engineering: Due to developments in Bioprinting, Synthetic Biology and Microfluidics, Tissue engineering enables regenerative medicines, treatment of burns, and organ transplant by creating grafts of autologous tissues. To create sustainable alternatives to meat, leather and such animal products, start-ups are using tissue engineering widening its scope from limited biomedical applications. Touching New Horizons: The most impactful trends from the list are AI (with 26% of the Biotech sector impacted), Big Data and Analytics (19%), Gene Editing (12%), and Precision medicine (10%). The remaining 33% shows impact of the rest from Gene Sequencing to Tissue Engineering. Surely Biotech is rapidly touching new horizons of our modern life. 40|November 2021|www.insightscare.com
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  • 46. Radiology and Imaging 5 trends in - by Meenakshi Singh, Co-founder and CEO, Synapsica With the growing popularity of minimally invasive procedures, there is a rising demand for accurate and efficient imaging technologies in both developed and developing countries. Radiology is one branch of diagnostic imaging that has kept up to date with the technological advances. In this year's conference of Radiological Society of North America, a society formed by radiologists and health scientists around the world, revolved the discussions mainly around technology and its adoption. The general trend is that Healthcare as an industry is quick when it comes to adapting to innovations and radiology as a subfield leads this change. Technological advancements, in the past few years, have led to major changes in the radiology industry and delivered crucial advantages to both the radiologists and the patients. Many radiologists and radiology centers today are employing AI to assist them for faster, more accurate and subjective reports. AI can easily spot a difference, as small as .001 micrometers, something which is not possible for the human eye to detect. It is because of this reason that radiologists and radiology centers that provide AI generated reports are seeing an uptick in the number of doctors approaching them for more reliable reports in the fastest possible time. In fact, when it comes to emergency and trauma cases, a 3X jump has been seen for AI powered reporting requests over the last few years. Other than the benefits of subjectivity, speed, remote reporting and more accuracy that AI is bringing in the radiology reporting, AI is also making it possible to detect a number of health issues precisely that are difficult to predict via traditional routes, like breast cancer, hemorrhagic stroke and lung cancer and spine degenerative diseases in advance and researches are on to detect more health issues that get missed especially at early stages. Also, thanks to technology, more and more radiologists are able to work remotely and handle almost 3X more caseload. Earlier, a lot of their time used to get lost in travelling to at least 3-4 centers in a day. It's a great support to the healthcare infrastructure in the country especially during the ongoing COVID pandemic when everyone must remain home to contain the spread. With these ongoing advancements and the potential in the field, lets look at a few trends in the Radiology and Imaging industry that we can expect in 2022. Trend #1 - AI in healthcare The pandemic accelerated the clinical adoption of AI. AI applications which were considered experimental applications pre-pandemic are now an integral part of 44|November 2021|www.insightscare.com
  • 47. y gsica ct a dict oke nce et are oad. at ain e ging Meenakshi Singh is the Co-founder and CEO at Synapsica, a health-tech platform for automating clinical and back-office radiology processes. Synapsica's AI based solutions automatically generate clinical interpretations of radiology scans right after the image capture, without any radiologist intervention. Meenakshi founded Synapsica in 2019 along with her co-founders, Kuldeep Singh Chauhan (CTO) and Dr Cherian (COO). She is responsible for fundraising, marketing and leads efforts for clinical validation and international regulatory compliance of the company's products. Under her aegis, Synapsica has helped in examining more than ten lakh patients. Before starting her entrepreneurial journey, Meenakshi worked with multiple giants including - Google, LoanIQ, Manhattan associates and Goldman Sachs. During her four years stint at Goldman Sachs, Meenakshi was instrumental in building quant-fin data analytics solutions to detect and prevent fraud and manipulation in the US financial markets for fixed income securities and complex derivatives. Time after time, Meenakshi has proven her tech acumen by implementing technology led changes in multiple companies. Meenakshi is a postgraduate from IIM Ahmedabad and pursued B.E Computer Science from Manipal Institute of Technology. She is an ardent mountaineer, and her goal is to climb mountains 6000 meters and above. About the Author 45|November 2021|www.insightscare.com
  • 48. clinical reporting flows in several large-scale medical centers. AI can be used for various functions such as diagnosis, triaging and workflow automation. Many organizations are looking to integrate AI and accelerate its usage for diagnosis. Trend #2 - Advances in imaging scanners and Hyperautomation Imaging scanners today are providing much in-depth information about a patient's body. For instance, Siemens PCD (Photon Counting Detector) CT machine, which was unveiled at this year's RSNA conference, can provide substantially better contrast and spatial resolution for near- realistic, cross-sectional images – a which means the system can capture even the most minute anatomical structures in a patient's body like- the smaller bronchi of the lungs or metastases in bones. This technology further reduces radiation exposure for patients while providing better diagnoses and hence opening up more use cases for CT scans. This is something which was unthinkable till just four years ago. Similarly, MRI and x-rays motion scanners today are using AI-based image reconstruction techniques which makes it much more economical and uncomplicated to maintain. Usage of advanced modalities has already increased by 43% and these advancements promise to further support this trend and further entrench diagnostic imaging in patient management protocols. Hyperautomation India has only 10,000 radiologists for a billion people. This shortage means that radiologists work overtime to report. However, technology has brought in an easier way for healthcare professionals to reduce their work by automating tasks. This is known as Hyperautomation. Advanced technologies such as AI and ML automate numerous tasks bringing down the rate of error and allowing professionals to concentrate on important cases. In fact, it is expected that by 2024, organizations can bring down their operational costs by 30% through the combination of Hyperautomation and redesigned operational processes. Trend #3 - Cross-discipline Collaboration Within Departments The internet has forever changed the healthcare landscape. It allows data to be shared through web APIs, enabling cross-disciplinary collaboration and knowledge pooling. With specialists collaborating with other healthcare experts, radiologists can apply integrated diagnostics using digital technology and move towards digitally reviewing images. Trend #4 - Telemedicine and teleradiology COVID-19 has created a need for telemedicine and teleradiology with even in-house panels reporting remotely. Traditional in-house PACS are being replaced with imaging systems that allow for collaboration remotely. There is an increasing need in healthcare for professionals to be able to access the patients records remotely and from across departments. Trend #5 - AI Orchestration AI orchestrations are the newest addition to the suite of software solutions available for the radiology industry. AI orchestration provides organizations with intelligence to automate the daily operations of the business. This helps reduce repetitive tasks and the workload of professionals enabling them to focus on specific cases. 46|November 2021|www.insightscare.com