The document discusses the management of stable COPD patients and acute exacerbations. For stable patients, management includes preventative measures like smoking cessation, nonpharmacological options like pulmonary rehabilitation, and pharmacological treatments like recommended guideline drugs or newer drugs. Acute exacerbation management involves bronchodilators, corticosteroids, and antibiotics. The document also reviews newer drug candidates for COPD like CXCR2 antagonists, P38 MAPK inhibitors, and mesenchymal stem cell therapy.