Additive manufacturing (AM) offers a few major benefits to biomedical applications. To improve the knowledge on AM possibilities, Sirris is organizing two different masterclasses. The first will address the technology, materials used and applications, with experts in the matter explaining all relevant aspects.
1. Masterclass:
Biomedical applications of
Additive Manufacturing
Part 01: General considerations and clinical case studies
2. Masterclass:
Biomedical applications of
Additive Manufacturing
Taking into consideration the biomechanical aspects:
anatomy and functional aspects of the body.
Prof. Bernardo Innocenti, PhD
BEAMS Department (Bio Electro and Mechanical Systems)
Ecole Polytechnique
Université Libre de Bruxelles
Av. F. Roosevelt, 50 CP165/56
1050 Bruxelles
3. The Speaker
Why Anatomy and Function
How we can determine Anatomy
How we can measure Function
What happen if Anatomy or Function changes
Take Home Message
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
3
4. Master Degree in Mechanical Engineering,
Department of Mechanical and Industrial Technology,
University of Florence;
PhD in Mechanical Design,
Department of Mechanical and Industrial Technology,
University of Florence
September 2003 - April 2007: Contract Professor,
University of Florence
January 2006 – April 2007: PostDoc,
Responsible of BioLAB
bernardo.innocenti@ulb.ac.be
May 2007 – September 2012:Lead Project Manager Numerical Kinematics
European Center for Knee Research, Smith & Nephew
Haasrode, Leuven, Belgium
2011 – Present: Guest Professor, Division of Biomechanics,
Department of Mechanical Engineering, KU Leuven
October 2012 - Present: Professor of Biomechanics
Université Libre de Bruxelles
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
4
5. Orthopaedic Numerical Knee
Biomechanics modeling biomechanics
Patient specific modeling
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
5
11. Patient profile is changing!!
Age Activity Higher
expectation
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
11
15. Frame
Upper leg (femur - Two dof)
• vertical movement
• rotation around ML axis
Lower leg (Tibia - Five dof)
• three rotations
• two translations
Two actuators
• One exerting a load on the hip (vertical sliding)
• One pulling the quadriceps
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
15
17. Hamstring Quadriceps
Extensometer TekScan Contact
Pressure Sensor
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
17
25. Lateral Condylar Centre Medial Condylar Centre
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
25
26. Hip Centre
FEMORAL MECHANICAL AXIS (FMA)
Insertion LCL
Knee Centre
Insertion MCL
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
26
27. FMA
Frontal plane FPF Includes FMAx and is parallel to EPI Ax
Sagittal plane SPF Includes FMAx and is perpendicular to FPF
Horizontal plane HPF Includes knee ctr and is perpendicular to FPF and SPF
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
27
28. Ankle
Centre
TIBIAL MECHANICAL AXIS (TMAx)
Medial
Lateral Condylar
Condylar Tibia Centre
Centre Centre
Frontal plane FPT Includes TMAx and is parallel to TTAx
Sagittal plane SPT Includes TMAx and is perpendicular to FPT
Horizontal plane HPT Includes tib ctr and is perpendicular to FPT and SPT
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
28
29. • 30 points pre-op CT scan
• 25 points post-op CT scan
• Identification protocol for each point
• Bony landmark definitions from literature when possible
LaPrade AJSM
LaPrade JBJS
• Control frame integrity on post-op CAT scan
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
29
30. kn
0
0.5
1
1.5
2
2.5
3
ee
ct
r
t ib
tu
b
hi
p
in ct
r
s
M
PF
L
F
an
kl
ct
r
in lcc
s
sM
CL
in F
s
LC
L
F
m
m cp
ed
co
nd
c
ad
d
tu
la b
tc
on
m d
ed c
co
nd
p
Masterclass: Biomedical applications of Additive Manufacturing
m
cc
Mean
pa
t ap
ex
m
ed
ep
i
pa
t la
t
t ib
ct
r
la
te
pi
pa
t pc
in r
s
LC
L
la fi
tc
on
d
p
t ip
f ib
pa
t dc
r
lcp
ga
st
tu
Organized by SIRRIS the 12th of March 2013
tro b
ch
pr
ox
30
33. Database Kinematics and Kinetics
70 cadaveric specimen(in progress)
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
33
36. Experimental Numerical
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
36
37. CT scan of a full Theoretical
cadaver leg Locations of tissues
physiological
insertion points
Bones reconstruction model
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
37
38. Analyzed TKA
Hinge
Fix Bearing
BCS design
Mobile
Bearing
Fix Bearing
PS design
Virtual cutting of the bones Theoretical
Design
design according to surgical replaced
technique model
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
38
39. Tibial Component Patellar Component
IE rotation
± 10°
Patella Alta/Baha
Tibial IE ± 3° configuration
Abb/Add ± 3°
Tibial Slope ± 3° BPI =0.59 - 1.29
ML translation ± 5mm
AP translation ± 5mm
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
39
40. Patellar Tendon
LCL and MCL
PD translation
PD translation ±5mm; ±5mm
AP translation ±5mm;
ML translation ±5mm;
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
40
41. [Innocenti et al., 2009a and 2009b; Victor et al., 2009 and 2010]
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
41
42. Maximum Patello-Femoral force
Alta Theoretical Baha
7
6
5
Patella Alta/Baja configurations
4
BW
3
2
1
0
PS Design BCS Design Hinge Design Mobile Bearing
Design
Medial and Lateral maximum Femoro-Tibial force
Alta lat Theoretical lat Baha lat
Singerman et al. (1994): 4 Alta med Theoretical med Baha med
3.5
PF contact force depends on patellar height; 3
2.5
Luyckx et al. (2009):
BW
2
PF force increases with patellar height; 1.5
1
Innocenti et al. (2009): 0.5
0
PF increases linearly with the increase of BP PS Design BCS Design Hinge Design Mobile Bearing
index. Design
Masterclass: Biomedical applications of Additive Manufacturing Organized by SIRRIS the 12th of March 2013
42