Contractile Filament Theory: Explained in three phases.

1. LykbfMax fQykesaV fl)kUr
(Sliding Filament Theory)
Dr. S. N. Singh
Department of Physical Education
S.D. (P.G.) College, Muzaffarnagar
Dr. S. N. Singh
Department of Physical Education
S.D. (P.G.) College, Muzaffarnagar

2. dksuVªsDVkbZy çfØ;k - LykbfMax
fQykesaV fl)kUr (Contractile Process - Sliding
Filament Theory)
bl fl)kr dk çfriknu ,p0 bZ0 gDlys (Hugh Esmor
Huxley - United Kingdom) us lu~ 1965 eas fd;k
FkkA buds lkFk bl [kkst esa ,.M: gDlys] jkYQ
fu,MjtsZdsZ rFkk thu gsulu (Andrew Huxley,
Ralph Niederjerke and Jean Henson) dk Hkh uke
vkrk gSA bldh [kkst ds fy;s ,p0 bZ0 gDlys dks
ukscy iq:Ldkj (Noble Prize) Hkh çnku fd;k x;k
FkkA ftlesa 'kks/k djus ds i'pkr ;g Lohdkj fd;k
x;k fd ekalis'kh; ladqpu LykbfMax fQykesaV
fl)kUr (Sliding filament Theory) ij vk/kfjr jgrh
dksuVªsDVkbZy çfØ;k - LykbfMax
fQykesaV fl)kUr (Contractile Process - Sliding
Filament Theory)
bl fl)kr dk çfriknu ,p0 bZ0 gDlys (Hugh Esmor
Huxley - United Kingdom) us lu~ 1965 eas fd;k
FkkA buds lkFk bl [kkst esa ,.M: gDlys] jkYQ
fu,MjtsZdsZ rFkk thu gsulu (Andrew Huxley,
Ralph Niederjerke and Jean Henson) dk Hkh uke
vkrk gSA bldh [kkst ds fy;s ,p0 bZ0 gDlys dks
ukscy iq:Ldkj (Noble Prize) Hkh çnku fd;k x;k
FkkA ftlesa 'kks/k djus ds i'pkr ;g Lohdkj fd;k
x;k fd ekalis'kh; ladqpu LykbfMax fQykesaV
fl)kUr (Sliding filament Theory) ij vk/kfjr jgrh

4. ekalis'kh; ladqpu dh
voLFkk fuEufyf[kr rhu
pj.kksa esa le>k;k tkrk
gSa :
A. vkjke dh voLFkk
(At Rest/ Relaxed)

5. eklis'kh;ksa esa dksbZ raf=dk vkosx (Nerve
Stimulus) ugha vkrsA
ek;ksflu esa dksbZ vkosx ugha gksrs (Myosin
uncharged) ftlds dkj.k ,0Vh0ih0 Økl fczt (ATP
cross bridge) nwj- nwj jgrs gS D;ksadh ,
0Vh0ih0 (A.T.P.) rFkk ,fDVu fQykeasV (Actin
Filament) dk Vªksiksfuu (Troponin) nksuks gh
nks usxsfVo pktZ (Negative Charge) ds lkFk
jgrs gSaA
,fDVu fQykeasV (Actin Filament) ds lkFk nks
izksVhu & Vªksiksfuu rFkk Vªksiksek;ksflu
(Troponin and Tropomyosin) jgrs gSa, ftlesa
Vªksiksfuu (Troponin) nks usxsfVo pktZ

6. dSfYl;e vk;u nks iksftfVo pktZ (Ca++
) ds
lkFk ekalisf'k;s dksf'kdk ds lkdksZIyklfed
jsfVdqye@,.MksIyklfedjsfVdqye(Sarcopla
smic Reticulam/Endoplasmic Reticulum)
esa ,df=r jgrs gSaA lkdksZIyklfed
jsfVdqye dks dSfYl;e vk;u dk Hk.Mkj x`g
dgk tkrk gSA
dSfYl;e vk;u nks iksftfVo pktZ (Ca++
) ds
lkFk ekalisf'k;s dksf'kdk ds lkdksZIyklfed
jsfVdqye@,.MksIyklfedjsfVdqye(Sarcopla
smic Reticulam/Endoplasmic Reticulum)
esa ,df=r jgrs gSaA lkdksZIyklfed
jsfVdqye dks dSfYl;e vk;u dk Hk.Mkj x`g
dgk tkrk gSA

7. ,fDVu fQykeasV (Actin Filament) ds nks çksVhu
Vªksiksfuu rFkk Vªksiksek;ksflu (Troponin and
Tropomyosin) viuh ,d fo'ks"k lajpuk ds dkj.k ,fDVu
(Actin) vkSj ek;ksflu (Myocin) dks vkil esa feyus
ugha nsrs D;ksafd Vªksiksfuu (Troponin) nks
usxsfVo pktZ (Negative charge) ds lkFk jgrk gaS,
rFkk ,0Vh0ih0 (ATP) Hkh ek;ksflu Øksl fczt
(Myosin Cross Bridge) ds ,d fljs ij nks usxsfVo
pktZ (Negative Charge) ds lkFk jgrk gS ftlds dkj.k
nksuks ,d nwljs ls nwj jgrs gSaA
H Zone fn[kkbZ nsrk gSA Z Line nwj &nwj jgrh
gSa vkSj ,fDVu (Actin) vkSj ek;ksflu vudiy fLFkfr
(Myosin uncoupled position) esa jgrs gSa, dgus dk
rkRi;Z nwj&nwj jgrs gSaA
,fDVu fQykeasV (Actin Filament) ds nks çksVhu
Vªksiksfuu rFkk Vªksiksek;ksflu (Troponin and
Tropomyosin) viuh ,d fo'ks"k lajpuk ds dkj.k ,fDVu
(Actin) vkSj ek;ksflu (Myocin) dks vkil esa feyus
ugha nsrs D;ksafd Vªksiksfuu (Troponin) nks
usxsfVo pktZ (Negative charge) ds lkFk jgrk gaS,
rFkk ,0Vh0ih0 (ATP) Hkh ek;ksflu Øksl fczt
(Myosin Cross Bridge) ds ,d fljs ij nks usxsfVo
pktZ (Negative Charge) ds lkFk jgrk gS ftlds dkj.k
nksuks ,d nwljs ls nwj jgrs gSaA
H Zone fn[kkbZ nsrk gSA Z Line nwj &nwj jgrh
gSa vkSj ,fDVu (Actin) vkSj ek;ksflu vudiy fLFkfr
(Myosin uncoupled position) esa jgrs gSa, dgus dk
rkRi;Z nwj&nwj jgrs gSaA

9. B. ladqpu dh voLFkk (At Contraction)
rafU=dk vkosx rafU=dk ds ,Dlksu (Axon)
ls ,lhVkbydksykbu ,UtkbZe (Acetylcoline
Enzyme - Ach) ds ekè;e ls fØ;kRed
ek¡lisf'k;ksa dh rjQ fØ;k djus (Action
Potential) ds fy, lkdksZfyek (Sarcolema) ds
ikl vkrs gSa, tgak ls ;g rUrq (Fibre)
ek¡lis'kh dh dksf'kdkvksa rd tkrs gSaA
fØ;k (Action-Potential) gsrq rUrq (Fibre) ds
ek;ksQkbcjhy (Myofibril) ds lkdksZIyklfed
jsfVdqye (Sarcoplasmic Reticulum) esa ls
dsfYl;e vk;u nks iksftfVo pktZ ds lkFk
(Ca++
) ckgj fudyrs gSaA

10. Vªksiksek;ksflu (Tropomyosin) dh jlk;fud
çfØ;k ds dkj.k dsfYl;e vk;u (Ca++
) dks ,fDVu
fQykeasV (Actin Filament) dk Vªksiksfuu
(Troponin) tks nks usxsfVo pktZ (Negative
Charge) ds lkFk gksrk gS vius nks usxsfVo
pktZ ds dkj.k viuh rjQ [khap ysrk gSaA
dSfYl;e vk;u dss nks ikWftfVo pktZ (Ca++
)
ek;ksflu ,0Vh0ih0 ØkWl fczt (Myosin ATP
Cross Bridge) ds nks usxsfVo pktZ dks
vkdf"kZr djrk gaSA

12. ,fDVu (Actin) vkSj ek;ksflu
(Myocin) ,d nwljs dh rjQ vkdf"kZr
gksdj f[kaprs gS vkSj ,fDVksek;ksflu
(Actomyosin) dk :i ys ysrs gaSA (A +
M - AM)
eks;ksflu (Myosin) ds fljs ij fLFkr ,
0Vh0ih0 (ATP) ls QksLQsV VwVdj ,
0Mh0ih0 rFkk buvksjxsfud QksLQsV
(ADP + Pi) esa ifjofrZr gks dj ÅtkZ
çnku djrk gaS, ftldks ge eks;ksflu

15. ek¡lis'kh ladfqpr (Muscle Contract) gks tkrh
gSA (ATP ADP + Pi Energy) gks bl fdz;k
dks ek;ksflu ,fVisl (Myosin ATPase) dgrs
gSaA
,p&tksu xk;c (H - zone Disappear) gks tkrs
gaS, rFkk ,fDVu (Actin), eks;ksflu
(Myosin) ij LykbM (Slide) dj tkrk gSA dgus
dk rkRi;Z ,fDVu (Actin) vkSj eks;ksflu
(Myosin) diy fLFkfr (Couple Position) esa
vk tkrs gSaA
ek¡lis'kh ladfqpr (Muscle Contract) gks tkrh
gSA (ATP ADP + Pi Energy) gks bl fdz;k
dks ek;ksflu ,fVisl (Myosin ATPase) dgrs
gSaA
,p&tksu xk;c (H - zone Disappear) gks tkrs
gaS, rFkk ,fDVu (Actin), eks;ksflu
(Myosin) ij LykbM (Slide) dj tkrk gSA dgus
dk rkRi;Z ,fDVu (Actin) vkSj eks;ksflu
(Myosin) diy fLFkfr (Couple Position) esa
vk tkrs gSaA

16. C. {kfriwfrZ voLFkk [At relaxation
(Recovery Phase)]
rafU=dk ds vkosx :d tkrs gaSA
Vªksiksfuu (Troponin) ls dsfYl;e vk;u (Ca++
)
fudydj lkdksZIyklfed jsfVdqye (Sarcoplasmic
Reticulum) esa okil ços'k dj tkrs gSA
ek;ksflu ,0Vh0ih0 Økl fczt vupktZ (Myosin
ATP Cross Bridge Uncharge) gks tkrk gaSA
,fDVu (Actin) vkSj ek;ksflu (Myosin) vudiy
fLFkfr (Uncouple Position) esa vk tkrs gSaA
dgus dk rkRi;Z nwj nwj gks tkrs gSaA
,0Vh0ih0 (ATP) iqu% curs (Resynthesis) gaSA
ek¡lis'kh vkjke dh fLFkfr esa vk tkrh gSA

17. /kU;okn