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1. ACUTE MYELOIDACUTE MYELOID
LEUKAEMIALEUKAEMIA
WHOWHO
CLASSIFICATIONCLASSIFICATION

2. AML with Recurrent GeneticAML with Recurrent Genetic
AbnormalitiesAbnormalities
 AML with t(8;21) RUNX1-RUNX1T1AML with t(8;21) RUNX1-RUNX1T1
 AML with inv (16) or t(16;16)AML with inv (16) or t(16;16)
 Acute promyelocytic leukaemia withAcute promyelocytic leukaemia with
t(15;17), PML-RARAt(15;17), PML-RARA
 AML with t(9;11), MLLT3-MLLAML with t(9;11), MLLT3-MLL
 AML with t(6;9),DEK-NUP214AML with t(6;9),DEK-NUP214
 AML with inv (3)AML with inv (3)

3. AML with Recurrent GeneticAML with Recurrent Genetic
AbnormalitiesAbnormalities
 AML (megakaryoblastic) with t(1;22),AML (megakaryoblastic) with t(1;22),
RBM15-MKL1RBM15-MKL1
 AML with mutated NPM1AML with mutated NPM1
 AML with mutated CEBPAAML with mutated CEBPA

4.  AML with myelodysplasia relatedAML with myelodysplasia related
changes.changes.
 Therapy related myeloid neoplasms.Therapy related myeloid neoplasms.
 Myeloid sarcoma.Myeloid sarcoma.
 Blastic plasmacytoid dendritic cellBlastic plasmacytoid dendritic cell
neoplasm.neoplasm.

5.  Acute myeloid leukaemia, NOSAcute myeloid leukaemia, NOS
 AML with minimal differentiationAML with minimal differentiation
 AML without maturationAML without maturation
 AML with maturationAML with maturation
 Acute myelomonocytic leukaemiaAcute myelomonocytic leukaemia
 Acute monoblastic and monocyticAcute monoblastic and monocytic
leukaemia.leukaemia.

6.  Acute erythroid leukaemiaAcute erythroid leukaemia
 Acute megakaryoblastic leukaemiaAcute megakaryoblastic leukaemia
 Acute basophilic leukaemiaAcute basophilic leukaemia
 Acute panmyelosis with myelofibrosis.Acute panmyelosis with myelofibrosis.

7.  Myeloid proliferations related toMyeloid proliferations related to
Down syndromeDown syndrome
 Transient abnormal myelopoiesisTransient abnormal myelopoiesis
 Myeloid leukaemia associated with DownMyeloid leukaemia associated with Down
syndromesyndrome