Enjoy our hands-on demonstration of the Doppler Flow Velocity System, a non-invasive, real-time pulsed Doppler measurement device for studying cardiovascular function in a variety of small animal models, such as mice and rats.
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Doppler Flow Velocity System
• Noninvasively evaluate cardiovascular physiology and
function.
• The system consists of four components:
• Pulsed Doppler Transceiver,
• Doppler Signal Digitizer,
• Doppler Workstation,
• and Handheld Probe.
• Surgical warming and real-time integration of ECG signals to
the DFVS software from the Rodent Surgical Monitor+.
• 2mm diameter handheld probe achieves ~15° angles.
Doppler Flow Velocity System 2
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Pulsed Doppler Ultrasound
• Achieving consistency and accuracy with
proper measurement angle…
• V = (c Δf) / (2fo cos θ)
• θ = angle between velocity vector & beam
vector
Doppler Flow Velocity
System
3
Optimal Angle = ~15°
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Using Pulsed Doppler Ultrasound
4
Advantages
Noninvasive - longitudinal studies
Short signal acquisition times
Can be measured at various locations
Signals from 2 sites can be combined
Possible to achieve small angles
Know-How
Knowledge of anatomy
Shapes and timing of waveforms
Doppler Flow Velocity
System
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Main Applications
Systolic & Diastolic Function
Confirmation and Stratification of TAC
Coronary Flow Reserve
Aortic/Arterial Stiffness
Peripheral Flow Perfusion
Doppler Flow Velocity System 5
Mouse Heart Mouse Aorta
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(Theta) is the angle between the line of blood flow and the doppler sound beam. This angle is important as anything under 15deg you wont see much difference in error, but above 15deg you’ll see exponential error increase and thus need angle correction, which also inherently has error.
SV is sample volume and represents