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HUMAN
CIRCULATORY
SYSTEM
www.yogalife.co.in
THE CIRCULATORY
SYSTEM
• Humans have a closed circulatory system, typical of
all vertebrates, in which blood is confined to vessels and is
distinct from the interstitial fluid.
• The heart pumps blood into large vessels
that branch into smaller ones leading into the organs, thus
also known as Cardio Vascular System.
• Materials are exchanged by diffusion between the blood
and the interstitial fluid bathing the cells.
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THE CARDIOVASCULAR
SYSTEM
3 Major Elements –
Heart
Blood Vessels
Blood
The Heart-
Cardiac muscle tissue with
highly interconnected cells.
Beats in a rhythmic manner,
72 times/min.
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HUMAN HEART
• Size
Of a closed fist
• Shape
Blunt cone
• Location
In the centre of the
thoracic cavity between
lungs. Lower tip is resting
on diaphragm slightly
towards left.
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CARDIOVASCULAR SYSTEM
THE HEART
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INTERNAL STRUCTURE OF
HUMAN HEART
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FUNCTIONS OF THE HEART
• Generating blood pressure
• Routing blood
– Heart separates pulmonary and systemic
circulations
• Ensuring one-way blood flow
– Heart valves ensure one-way flow
• Regulating blood supply
– Changes in contraction rate and force match blood
delivery to changing metabolic needs
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BLOOD FLOW THROUGH
HEART
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CIRCUITS
• Pulmonary circuit
The blood pathway
between the right side of
the heart, to the lungs, and
back to the left side of the
heart.
• Systemic circuit
The pathway between the
left and right sides of the
heart via body organs.
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CARDIAC CYCLE
• Right and left halves of the Heart represent two pumps that
work together.
• Repetitive contraction (systole) and relaxation (diastole) of
heart chambers, one after the other.
• Blood moves through circulatory system from areas of
higher to lower pressure.
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CONDUCTING SYSTEM OF
HEART
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HEART SOUNDS
• First heart sound or “lubb”
– Atrioventricular valves and surrounding fluid vibrations
as valves close at beginning of ventricular systole
• Second heart sound or “dupp”
– Results from closure of aortic and pulmonary semilunar
valves at beginning of ventricular diastole, lasts longer
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BLOOD VESSELS
Blood Vessels -A network of tubes
Arteriesarterioles move away from the heart
Valves are absent
Capillaries – where gas exchange takes place.
One cell thick
Serves the Respiratory and other Systems
VeinsVenules moves towards the heart
One way valves
When they break - varicose veins form
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BLOOD VESSELS
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BLOOD VESSELS
ARTERIES
• Carry blood away from the heart
• Thick and strong, containing muscles and elastic tissue.
• Relatively narrow, it varies with heart beat, as it can stretch and recoil.
CAPILLARIES
• supply all cells with their requirements and take away waste products.
• Very thin, only one cell thick.
• Very narrow, just one cell can pass through.
VEINS
• Return blood to the heart
• Quite thin, containing less muscle and elastic tissue.
• Wide, contains valves
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BLOOD VESSELS
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BLOOD
Composition of Blood
1. Plasma
2. Formed Elements-
RBC, WBC, Platelets
Plasma
Liquid portion of the blood.
Contains water, salts, proteins,
clotting factors, hormones,
antibodies, dissolved gases,
nutrients and waste
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BLOOD
Formed Elements
A. Erythrocytes – RBC
(Red Blood Corpuscles)
Contain 12-16 gms of
hemoglobin to carry
oxygen.
Do not have a nucleus and
live only about 120 days.
5-5.5 million/cubic mm
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BLOOD
B. Leucocytes –WBC
(White Blood cells)
Five types – neutrophils,
lymphocytes, eosinophils,
basophils, and monocytes.
Fight infection and are formed in
the bone marrow
Nucleated cells
6000-8000/cubic mm
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BLOOD
•C. Thrombocytes – Platelets.
These are cell fragment that are
formed in the bone marrow
from magakaryocytes.
Initiate Clotting of Blood.
1,500,00 - 3,500,00/cubic mm
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FUNCTIONS OF BLOOD
• Transport food and waste
• Transport oxygen and carbon di oxide
• Transport hormones
• Storehouse of salts, nutrients, calcium etc.
• Maintain a constant body temperature
• Provide resistance against infections
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REGULATION OF THE HEART
Intrinsic regulation: Results from normal functional
characteristics, not on neural or hormonal regulation
Extrinsic regulation: Involves neural and hormonal control,
Cardiac centre is in Medulla Oblongata.
– Parasympathetic stimulation
• Supplied by vagus nerve, decreases heart rate,
acetylcholine secreted
– Sympathetic stimulation
• Supplied by cardiac nerves, increases heart rate and
force of contraction, epinephrine and nor epinephrine
released
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REGULATION OF THE HEART
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DISORDERS OF THE
CIRCULATORY SYSTEM
• Anaemia - lack of iron in the blood, low RBC count
• Leukemia - white blood cells proliferate wildly, causing anaemia
• Haemophilia - bleeder’s disease, due to lack of clotting factor
• Hypertension – High blood pressure
• Angina – Less oxygen supply to heart muscles
• CAD – Obstructed blood vessels
• Heart Failure – Heart is not pumping blood properly
• Heart attack - blood vessels around the heart become blocked with plaque, also
called myocardial infarction, leads to damage of muscles
• Cardiac Arrest – Heart stops working leading to death
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THANK YOU
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Human circulatory system

  • 2. THE CIRCULATORY SYSTEM • Humans have a closed circulatory system, typical of all vertebrates, in which blood is confined to vessels and is distinct from the interstitial fluid. • The heart pumps blood into large vessels that branch into smaller ones leading into the organs, thus also known as Cardio Vascular System. • Materials are exchanged by diffusion between the blood and the interstitial fluid bathing the cells. www.yogalife.co.in
  • 3. THE CARDIOVASCULAR SYSTEM 3 Major Elements – Heart Blood Vessels Blood The Heart- Cardiac muscle tissue with highly interconnected cells. Beats in a rhythmic manner, 72 times/min. www.yogalife.co.in
  • 4. HUMAN HEART • Size Of a closed fist • Shape Blunt cone • Location In the centre of the thoracic cavity between lungs. Lower tip is resting on diaphragm slightly towards left. www.yogalife.co.in
  • 6. INTERNAL STRUCTURE OF HUMAN HEART www.yogalife.co.in
  • 7. FUNCTIONS OF THE HEART • Generating blood pressure • Routing blood – Heart separates pulmonary and systemic circulations • Ensuring one-way blood flow – Heart valves ensure one-way flow • Regulating blood supply – Changes in contraction rate and force match blood delivery to changing metabolic needs www.yogalife.co.in
  • 9. CIRCUITS • Pulmonary circuit The blood pathway between the right side of the heart, to the lungs, and back to the left side of the heart. • Systemic circuit The pathway between the left and right sides of the heart via body organs. www.yogalife.co.in
  • 10. CARDIAC CYCLE • Right and left halves of the Heart represent two pumps that work together. • Repetitive contraction (systole) and relaxation (diastole) of heart chambers, one after the other. • Blood moves through circulatory system from areas of higher to lower pressure. www.yogalife.co.in
  • 12. HEART SOUNDS • First heart sound or “lubb” – Atrioventricular valves and surrounding fluid vibrations as valves close at beginning of ventricular systole • Second heart sound or “dupp” – Results from closure of aortic and pulmonary semilunar valves at beginning of ventricular diastole, lasts longer www.yogalife.co.in
  • 13. BLOOD VESSELS Blood Vessels -A network of tubes Arteriesarterioles move away from the heart Valves are absent Capillaries – where gas exchange takes place. One cell thick Serves the Respiratory and other Systems VeinsVenules moves towards the heart One way valves When they break - varicose veins form www.yogalife.co.in
  • 15. BLOOD VESSELS ARTERIES • Carry blood away from the heart • Thick and strong, containing muscles and elastic tissue. • Relatively narrow, it varies with heart beat, as it can stretch and recoil. CAPILLARIES • supply all cells with their requirements and take away waste products. • Very thin, only one cell thick. • Very narrow, just one cell can pass through. VEINS • Return blood to the heart • Quite thin, containing less muscle and elastic tissue. • Wide, contains valves www.yogalife.co.in
  • 17. BLOOD Composition of Blood 1. Plasma 2. Formed Elements- RBC, WBC, Platelets Plasma Liquid portion of the blood. Contains water, salts, proteins, clotting factors, hormones, antibodies, dissolved gases, nutrients and waste www.yogalife.co.in
  • 18. BLOOD Formed Elements A. Erythrocytes – RBC (Red Blood Corpuscles) Contain 12-16 gms of hemoglobin to carry oxygen. Do not have a nucleus and live only about 120 days. 5-5.5 million/cubic mm www.yogalife.co.in
  • 19. BLOOD B. Leucocytes –WBC (White Blood cells) Five types – neutrophils, lymphocytes, eosinophils, basophils, and monocytes. Fight infection and are formed in the bone marrow Nucleated cells 6000-8000/cubic mm www.yogalife.co.in
  • 20. BLOOD •C. Thrombocytes – Platelets. These are cell fragment that are formed in the bone marrow from magakaryocytes. Initiate Clotting of Blood. 1,500,00 - 3,500,00/cubic mm www.yogalife.co.in
  • 21. FUNCTIONS OF BLOOD • Transport food and waste • Transport oxygen and carbon di oxide • Transport hormones • Storehouse of salts, nutrients, calcium etc. • Maintain a constant body temperature • Provide resistance against infections www.yogalife.co.in
  • 22. REGULATION OF THE HEART Intrinsic regulation: Results from normal functional characteristics, not on neural or hormonal regulation Extrinsic regulation: Involves neural and hormonal control, Cardiac centre is in Medulla Oblongata. – Parasympathetic stimulation • Supplied by vagus nerve, decreases heart rate, acetylcholine secreted – Sympathetic stimulation • Supplied by cardiac nerves, increases heart rate and force of contraction, epinephrine and nor epinephrine released www.yogalife.co.in
  • 23. REGULATION OF THE HEART www.yogalife.co.in
  • 24. DISORDERS OF THE CIRCULATORY SYSTEM • Anaemia - lack of iron in the blood, low RBC count • Leukemia - white blood cells proliferate wildly, causing anaemia • Haemophilia - bleeder’s disease, due to lack of clotting factor • Hypertension – High blood pressure • Angina – Less oxygen supply to heart muscles • CAD – Obstructed blood vessels • Heart Failure – Heart is not pumping blood properly • Heart attack - blood vessels around the heart become blocked with plaque, also called myocardial infarction, leads to damage of muscles • Cardiac Arrest – Heart stops working leading to death www.yogalife.co.in