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ExpensesU.S. CurrencyTotal 5 year Budget ProjectionFormula
(see detail below)Conversion RateLocal currencyU.S.
currencySourceTransportationNumberNumberLink or
citationItemQtyPrice each (Local)Price each (US)Total price
(US)Projected Price (US)SourceDescriptionnumbersnumber or
NANumber or NAFormulasFormulasLink or citationInflation
RateCPI (Five Years Ago)CPI (Today)Inflation Rate(Add rows
as needed)NumberNumberFormulaLodgingItemQtyPrice each
(Local)Price each (US)Total price (US)Projected
PriceDescriptionnumbersnumber or NANumber or
NAFormulasFormulasLink or citation(add rows as needed)Food
ItemQtyPrice each (Local)Price each (US)Total price
(US)Projected PriceDescriptionnumbersnumber or NANumber
or NAFormulasFormulasLink or citation(add rows as
needed)Supplies and MiscItemQtyPrice each (Local)Price each
(US)Total price (US)Projected PriceNumbersnumbersnumber or
NANumber or NAFormulasFormulasLink or citation(add rows
as needed)
Funding-Population ProjectionSponsorshipFundraisingLoan
(remainder of trip expenses, or minimum of $10,000)Invest 30%
of budget balance for 5 years$100 monthly for 5 yearsBank
ABank
BPrincipalFormulaPayment100PrincipalFormulaFormularnumbe
rLink or citationrnumberLink or citationrnumberLink or
citationnumberLink or citationMust be different
ratesnnumbernnumbernnumbernumbertnumbertnumbertnumbern
umberMust be different yearsTotal in 5 yearsFormulaTotal in 5
yearsFormulaPaymentFormulaFormulaTotal
PaidFormulaFormulaTotal interestFormulaFormulaPopulation
ProjectionCurrent populationNumberAnnual Growth
RateNumberLink or citationProjected Population Formula
In complete sentences and with complete reasoning, please
answer which bank gives the better loan deal? Why?
Answer:
Running head: ANNOTATED BIBLIOGRAPHY 1
ANNOTATED BIBLIOGRAPHY 5
Annotated bibliography
Alesix Tieku
Professor Priyanthi Silva
HMGT 302 (6381)
February 01, 2019
Annotated bibliography
Reference
Alzheimer’s, A. (2015). 2015 Alzheimer's disease facts and
figures. Alzheimer's & dementia: the journal of the Alzheimer's
Association, 11(3), 332.
The above report focuses on public health and the impacts the
Alzheimer’s diseases (AD), it includes all the incidences and
the prevailing mortality rates. It also covers cost incurred for
caring and also the effect felt by the care givers and the society
at large. This report focuses the issues encountered by the
health care providers as they try to disclose the AD diagnosis to
the patients as well as the care givers. Approximately 5.29
million Americans are diagnosed with AD; 200,000 have an
average of below 65 years and 5.1 million are about 65 years. In
the U.S. someone will develop AD after every 67 seconds. The
expectations are that by 2050, AD will develop after every 33
seconds which will result to nearly a million cases per year. Ad
is the sixth leading cause of death in the U.S. disclosure of the
AD is usually too hard for the health specialists. Improvement
of the disclosure process is supposed to be improved. This
article will be useful as I develop my paper since it is much
elaborate on the issue of the AD and also gives the statistics on
the rate of the infection and so it verses me with the required
information to develop an elaborate paper.
Bird, T. D. (2015). Alzheimer disease overview
According to the above reference, the characteristic of AD is
Dementia which typically starts with a subtle as well as memory
failure which in turn become incapacitating. There are also
other r common findings which include poor judgment,
confusion, agitation, language disturbance as well as
hallucinations. Sometimes seizures are experienced, increased
muscle tones, incontinence, myoclonus and mutism also occurs.
Death is caused by malnutrition, pneumonia and general
inanition. The recommended clinic duration is usually between
8 to 10 years. As we note from the above reference, the disease
is explained in details and this gives me the knowledge of the
characteristics of the disease and also the characteristics. This
is very important in my paper since it provides me with the best
knowledge on the characteristics and the symptoms of the
disease.
Kumar, A., & Singh, A. (2015). A review on Alzheimer's
disease pathophysiology and its management: an update.
Pharmacological Reports, 67(2), 195-203.
According to Anil Kumar AD disease is known to be a
neurodegenerative disorder that is multifarious and progressive.
He further explains that this disease is the major cause of
Dementia especially in the late adult life. According to
pathology, AD is usually characterized by the intracellular
tangle of neurofibrillary and also the deposits of the
extracellular amyloidal proteins that bring about plaques of
senile. The advancing study of pathogenesis has inspired the
investigation of therapeutic study towards the
pathophysiological events. The reference explains deeply about
AD and also mentions the diseases major cause. The
information provided is helpful in my paper since it gives
details of the cause of AD.
Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G.,
Huntley, J., Ames, D., ... & Cooper, C. (2017). Dementia
prevention, intervention, and care. The Lancet, 390(10113),
2673-2734.
In the paper above, Gill and his counterparts tackle the issue
about the safety measures to be taken. They say that acting now
on ways to prevent AD and intervene as well as exercising care
to the infected can largely improve the living. Cases of death
will be minimal due to the presence of a vast knowledge about
the disease. The lives of people leaving with dementia and their
families will improve and by so doing this will significantly
bring a transformation to the future of the society. This
reference gives the details on how we are supposed to handle
the situation of people living with dementia. This knowledge is
of much significance to my paper because as much as I will
discuss the dementia disease, I will also need to talk about how
to live with the infected.
Nelson, L., & Tabet, N. (2015). Slowing the progression of
Alzheimer’s disease; what works?. Ageing research reviews, 23,
193-209.
In this reference, Lucy and Naji explain that Alzheimer’s
disease is a disease associated with age and dementia progresses
with the age and it is increasing worldwide. It typically affects
the short term memory as it onsets. This illness which is
devastating advances until it brings impaireness to all the
aspects associated with cognitive and the non-cognitive domain
too. Nowadays a lot of effort has been put in place a disease
modifying treatment or medication but the most promising get
faltered during the preclinical research. Because of that failure
to get an effective medication, the all the efforts have been
shifted to gaining insight on the preventive measures. The
authors of this reference explain the efforts that are put in place
in order to counter the problem of the increasing disease.
Robinson, L., Tang, E., & Taylor, J. P. (2015). Dementia:
timely diagnosis and early intervention. Bmj, 350, h3029
Robinson, Tang and Taylor explain their efforts for searching
for articles thro Medline, coochrane as well as the pub med and
also did research of the available systematic reviews from 2006
all the way to 2014. They talked about pharmacologic treatment
as well as the non-pharmacologic treatment. They further
explain strategies/interventions and treatment. They also focus
on systematic reviews and the Meta analysis and the high
quality randomized trials based on control. The authors also
include the expected figures of who will have dementia in the
future. They further explain the cause of delayed diagnosis.
Such information is of much help to me as I develop and
advance in writing may paper which should be detailed.
Rosenberg, P. B., Nowrangi, M. A., & Lyketsos, C. G. (2015).
Neuropsychiatric symptoms in Alzheimer's disease: what might
be associated brain circuits?. Molecular aspects of medicine, 43,
25-37.
According to the above researchers,
Neuropsychiatric symptoms (NPS) are usually very common in
the AD disease in particular, apathy, agitation, delusions and
depressions. All the brain networks or the circuits where these
symptoms underlie are now trying to be understood. The
growing neurochemical evidence together with imaging form a
base to the understanding of the potential mechanisms of the
Neuropsychiatric symptoms (NPS). The authors also offer
review of the recent literature and even an hypotheses
concerning networks or the circuit’s which underlie these NPS
in particular the apathy, agitation and even the delusions. This
informationis found in details as we continue analyzing the
book. It gives a clear outline on NPS symptoms common in the
AD.
Stokes, G. (2017). Challenging behavior in dementia: a person-
centred approach. Routledge.
Graham stokes explains how he never intended
to work in the field of dementia. He thought that this could be
as a result of lack of ambition or due to poor judgment. He was
attracted to neuropsychology and also to research on
management of dementia. He says that all the people that spent
time with those infected by dementia should be appreciated. He
says that working with the people whose memories are failing
should be appreciated. He further explains the need to manage
the rapidly ensuing problem. The main purpose of his book is to
rapidly communicate about the expanding knowledge of the
psychology the Dementia disease. This information is good for
my paper since it gets me to know more about the psychology of
the disease.
Winblad, B., Amouyel, P., Andrieu, S., Ballard, C., Brayne, C.,
Brodaty, H., ... & Fratiglioni, L. (2016). Defeating Alzheimer's
disease and other dementias: a priority for European science and
society. The Lancet Neurology, 15(5), 455-532.
Winblad and his team in this book explain that
Alzheimer’s disease (AD) tops the list of causing Dementia.
They further state that dementia increases with an increase in
the age globally. This disease affects even the wealthier
countries and the medical care cost is usually a burden since the
numbers of Dementia infections increase overwhelmingly since
almost everybody is living into old age. They explain the effort
of the government and the policy makers as they make
incentives that provide more resources to develop AD
therapeutics. This shows that it is a national disaster and a
threat to everyone.
Zhao, Q. F., Tan, L., Wang, H. F., Jiang, T., Tan, M. S., Tan,
L., ... & Yu, J. T. (2016). The prevalence of neuropsychiatric
symptoms in Alzheimer's disease: systematic review and meta-
analysis. Journal of affective disorders, 190, 264-271.
Finally Zhao and his team explain that (NPS)
symptoms are progressively recognized as a common serious
problem in the AD disease. They further say that the data
provided on the prevalence of NPS in the people with AD do
conflict with the meta- analysis that is aimed at to approximate
the prevalence of the NPS. All the above information is
necessary in the development of my paper since it will be much
detailed and it will discuss and touch on every bit concerning
the AD disease.
Alesix Tieku
Gero 302 (6381)
Topic: Dementia (Alzheimer's Disease)
References
Alzheimer’s, A. (2015). 2015 Alzheimer's disease facts and
figures. Alzheimer's & dementia: the journal of the Alzheimer's
Association, 11(3), 332.
Bird, T. D. (2015). Alzheimer disease overview.
Kumar, A., & Singh, A. (2015). A review on Alzheimer's
disease pathophysiology and its management: an
update. Pharmacological Reports, 67(2), 195-203.
Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G.,
Huntley, J., Ames, D., ... & Cooper, C. (2017). Dementia
prevention, intervention, and care. The Lancet, 390(10113),
2673-2734.
Nelson, L., & Tabet, N. (2015). Slowing the progression of
Alzheimer’s disease; what works?. Ageing research reviews, 23,
193-209.
Robinson, L., Tang, E., & Taylor, J. P. (2015). Dementia:
timely diagnosis and early intervention. Bmj, 350, h3029.
Rosenberg, P. B., Nowrangi, M. A., & Lyketsos, C. G. (2015).
Neuropsychiatric symptoms in Alzheimer's disease: what might
be associated brain circuits?. Molecular aspects of medicine, 43,
25-37.
Stokes, G. (2017). Challenging behaviour in dementia: a person-
centred approach. Routledge.
Winblad, B., Amouyel, P., Andrieu, S., Ballard, C., Brayne, C.,
Brodaty, H., ... & Fratiglioni, L. (2016). Defeating Alzheimer's
disease and other dementias: a priority for European science and
society. The Lancet Neurology, 15(5), 455-532.
Zhao, Q. F., Tan, L., Wang, H. F., Jiang, T., Tan, M. S., Tan,
L., ... & Yu, J. T. (2016). The prevalence of neuropsychiatric
symptoms in Alzheimer's disease: systematic review and meta-
analysis. Journal of affective disorders, 190, 264-271.
Alesix Tieku
Topic Selection
Dementia
There are various types of Dementia i.e. Alzheimer’s disease,
vascular dementia, dementia with Lewy bodies (DLB),
Huntington Disease, Parkinson Disease Dementia and mixed
dementia and lots more.
I will be focusing on Alzheimer’s Disease, causes and
symptoms, treatment and diagnosis.
Alzheimer's is a disease that robs people of their memory. At
first, people have a hard time remembering recent events,
though they might easily recall things that happened years ago.
The HOPE for Alzheimer’s Act (S. 857 /H.R. 1559): Passage of
this bill would provide comprehensive care planning services—
for both the individual and his/her caregiver— following a
dementia diagnosis. Michael Splaine, a long-time advocate and
principal of Splaine Consulting, a healthcare policy firm that
specializes in Alzheimer’s issues
External link disclaimer
, is optimistic about the HOPE Act—as the bill is supported by
nearly half of the Senate and boasts over 200 House co-
sponsors.
The National Alzheimer’s Plan is essentially a call to public
preparedness for addressing Alzheimer’s, with Goal 3 of the
Plan focused on caregiver support. Many advocates are voicing
the need for state Alzheimer’s plans too.
The Alzheimer’s Caregiver Support Act (H.R. 3090
External link disclaimer
) will provide grants to public and non-profit organizations to
expand and improve training and support services for families
and caregivers of individuals with Alzheimer’s disease.
The RAISE Family Caregivers Act of 2015 (H.R. 3099/S.1719
External link disclaimer
) would facilitate the establishment of a national strategy to
address the many issues facing caregivers today, including
education and training, long-term services and supports, and
financial stability and security.
References:
https://currents.greatcall.com/categories/news-policy/whats-
happening-in-alzheimers-policy-and-why-it-matters/
1. Albania
2. Algeria
3. Andorra *
4. Argentina
5. Armenia
6. Belarus
7. Bosnia & Herzegovina
8. Burkina Faso *
9. Chad
10. Djibouti *
11. Gabon *
12. Guatemala
13. Indonesia
14. Iran
15. Lesotho *
16. Macedonia
17. Malawi *
18. Mali
19. Mongolia
20. Morocco
21. Nauru *
22. Niger
23. Niue
24. Papua New Guinea *
25. Seychelles *
26. Sierra Leone
27. Sri Lanka
28. Suriname
29. Yemen
30. Zimbabwe *
MAT-144 Major Assignment #3 Details
Overview:
You and some of your friends want to travel to another country
to provide aid in the form of a mission trip. You have been
chosen as the team leader, and your job is to provide a plan for
the trip, including a financial plan. This is a big job, and you
want to do it right, so you and your team have agreed that the
trip will take place 5 years from now. Requirements for the trip:
Who: You and 5-10 other individuals will travel to provide aid.
When: 5 years in the future. The trip will last 2-4 weeks. This is
not a large scale, so you should think carefully about what you
can accomplish with a team of this size and time frame.
What: This trip’s main purpose will be to fill some sort of
tangible need to improve the day-to-day life of the people you
meet. Therefore, your first job will be to decide what your team
has to offer and to find a location where there is a need for your
talents. You should think about what you can do to alleviate
human suffering by working in an area of education, health
care, basic supplies (such as clothing or home goods), housing,
food or clean water, or work to repair the local environment. If
you want to include evangelism as a secondary goal, that is fine,
but the criteria you will be graded on is how you make a
difference in the day-to-day lives of the people you work with.
Where: You will travel overseas. To keep your project
manageable, you must choose one of the locations on the
Country List, which is included as an attachment to this
assignment. Because of the size of the team and your time
frame, you should narrow down your area within the country to
fit your project. For example, you can’t expect to provide
vaccines to the entire country of Brazil, but you could
reasonably expect to provide this service to a small town in the
country. So you will need to find an area within your chosen
country to focus on. The people that you serve in this area are
members of your target population.Requirements for the
assignment:
This assignment will have two parts.
Part 1: You create a PowerPoint presentation describing the trip
and explaining why the specific country has been chosen. The
presentation should have a minimum of eight slides – a title
slide, one for each category below, and a reference slide. All
important information should be on the face of the slides but
you can submit speaker notes for greater detail. In addition, you
will need a minimum of three scholarly resources (see the
resource list below for ideas) and the presentation should
address the following areas:
1. An overview of your purpose for the project: Where are
going, and what service will you be providing? Remember,
evangelism cannot be the sole purpose of your trip or even the
primary purpose.
2. Cultural and social aspects of the country and its population
that led you to choose this area of the world.
3. How your choice of project works toward fulfillment of the
Judeo-Christian-Islamic ideal to love your neighbor as yourself:
How does your personal worldview and the possible worldviews
of your target population influence your plans for the trip?
4. Information about your target population: Who are you
planning to serve? How does this population compare to the
population of the country as a whole? You will also need to do a
calculation to project either the general or the target population
in 5 years in the spreadsheet but it does not need to be
discussed in the presentation. The World Factbook provides
population growth data to help you here.
5. Information about the economic situation in your country and
how your project will improve this.
6. Possible concerns that you need to keep in mind to keep your
team and your target population safe. This could be safety from
violence or from health problems (for example, will your team
need inoculations to travel to the country).
Part 2: A financial plan for your trip, which you will include in
the provided Excel spreadsheet. Your financial plan needs to
include the following information:
1. A list of expenses for all members of your trip. This must
include the following:
a. Travel expenses, such as plane or bus fare, passports/visas,
local travel within the country. Plane fare can be in U.S.
dollars, but the local travel will need to be in the local currency
of the country you visit.
b. Lodging expenses. If you plan to camp, you will include
expenses for your camping gear. If you are planning to stay
with a host church or host family, you should research the cost
of lodging in your target area and provide a per diem donation
that is commensurate with the local lodging rates. This will be
in the local currency.
c. Food expenses while you are overseas. Again, if you are
being fed by local residents, you will research the approximate
cost to feed your group and provide a per diem donation to
cover expenses. One way to do this is to research cost of living
in your country to find out what a local family would expect to
budget to pay for food. Again, these costs will be in the local
currency.
d. Supplies for your project. Provide at least four items that you
will need to complete your project. Depending on the nature of
your project, these might be in U.S. dollars, or in the local
currency, or they may be a mix.
e. For your expenses that are given in the local currency, a
conversion to U.S. dollars.
f. For each expense, you will use the CPI data from the Bureau
of Labor Statistics to calculate your estimated expense 5 years
in the future.
g. A grand total of all projected expenses 5 years from now.
2. Funding sources for your trip.
a. Sponsorship: You are going to assume that you can find a
sponsor who can provide 30% of your grand total of all
expenses for seed money, and you will invest that money in a
savings account for the next 5 years. Research current savings
rates and calculate what this amount will grow to over the next
5 years.
b. Savings: Your team will work on various fundraisers to save
for the trip, and you estimate that you can raise $100 a month
every month over the next 5 years, which you will also put into
a savings account. Using the savings rates you found in part a.,
calculate what these regular savings amounts will grow to over
the next 5 years.
c. Loan: If your sponsorship and savings totals do not cover
your expenses, then you will need to take out a loan for the
remainder of your expenses. Even if your sponsorship and
savings total do cover all expenses, then you will take out a
$10,000 loan for an additional emergency cushion. Research
loan rates from two banks, and calculate the monthly payment,
total that you pay back to the bank and total interest you will
pay for each loan. You will indicate in the spreadsheet which of
the two loans is a better choice for you and your reasons
why.Resources
You should plan to use the following resources to help you with
your plan. You can also use other resources, but at a minimum,
you will need the Excel Budget Spreadsheet, BLS CPI data, and
CIA World Factbook. Additionally, your paper requires three
scholarly sources.
· Country list.docx: Includes the list of countries you are
allowed to choose from for this project, along with some
important facts about the country’s make up.
· Bureau of Labor Statistics Consumer Price Data information:
https://data.bls.gov/cgi-bin/surveymost?cu which is the same as
on Worksheet 2.
· CIA World Fact Book: You must use this source. You will
find that it contains a wealth of demographic, economic, and
cultural information about your country.
https://www.cia.gov/library/publications/the-world-factbook/
· U.S. Department of State website: This site will give you
important information about your country, as well as
information about travel overseas.
https://travel.state.gov/content/travel/en/international-
travel/International-Travel-Country-Information-Pages.html
· Excel Budget Spreadsheet: Attached to the assignment
directions, and provides a compact way to explain your budget
and funding.
· Your course textbook
· GCU LibraryTips and formulas:
· This assignment uses a rubric. Please be sure to look at the
grading criteria and point values for each area of the rubric to
see how you will be graded on this assignment.
· Compound interest formula (also called the Lump Sum
Investment formula) formatted for EXCEL: A = P * ((1 +
r/n)^(n * t).
· A is the accrued amount after t years that the principal, P,
grows to at interest rate, r%, compounded n times each year.
· Regular payments formula (also called the Savings Plan
formula) formatted for EXCEL: A = PMT * ((1 + r/n)^(n * t)-
1)/(r/n).
· A is the accrued amount after t years of making regular
payments, PMT, into an account at interest rate, r%,
compounded n times each year.
· Loan payment formula formatted for EXCEL: PMT = P *
(r/n)/(1 – (1 + r/n)^(-n*t)).
· PMT is the payment required to pay off a loan of $P at interest
rate, r%, compounded n times per year for t years.
· Percent change IR = (new CPI – old CPI)/old CPI where IR is
inflation rate.

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ExpensesU.S. CurrencyTotal 5 year Budget ProjectionFormula (see de.docx

  • 1. ExpensesU.S. CurrencyTotal 5 year Budget ProjectionFormula (see detail below)Conversion RateLocal currencyU.S. currencySourceTransportationNumberNumberLink or citationItemQtyPrice each (Local)Price each (US)Total price (US)Projected Price (US)SourceDescriptionnumbersnumber or NANumber or NAFormulasFormulasLink or citationInflation RateCPI (Five Years Ago)CPI (Today)Inflation Rate(Add rows as needed)NumberNumberFormulaLodgingItemQtyPrice each (Local)Price each (US)Total price (US)Projected PriceDescriptionnumbersnumber or NANumber or NAFormulasFormulasLink or citation(add rows as needed)Food ItemQtyPrice each (Local)Price each (US)Total price (US)Projected PriceDescriptionnumbersnumber or NANumber or NAFormulasFormulasLink or citation(add rows as needed)Supplies and MiscItemQtyPrice each (Local)Price each (US)Total price (US)Projected PriceNumbersnumbersnumber or NANumber or NAFormulasFormulasLink or citation(add rows as needed) Funding-Population ProjectionSponsorshipFundraisingLoan (remainder of trip expenses, or minimum of $10,000)Invest 30% of budget balance for 5 years$100 monthly for 5 yearsBank ABank BPrincipalFormulaPayment100PrincipalFormulaFormularnumbe rLink or citationrnumberLink or citationrnumberLink or citationnumberLink or citationMust be different ratesnnumbernnumbernnumbernumbertnumbertnumbertnumbern umberMust be different yearsTotal in 5 yearsFormulaTotal in 5 yearsFormulaPaymentFormulaFormulaTotal PaidFormulaFormulaTotal interestFormulaFormulaPopulation ProjectionCurrent populationNumberAnnual Growth RateNumberLink or citationProjected Population Formula In complete sentences and with complete reasoning, please answer which bank gives the better loan deal? Why? Answer:
  • 2. Running head: ANNOTATED BIBLIOGRAPHY 1 ANNOTATED BIBLIOGRAPHY 5 Annotated bibliography Alesix Tieku Professor Priyanthi Silva HMGT 302 (6381) February 01, 2019 Annotated bibliography Reference Alzheimer’s, A. (2015). 2015 Alzheimer's disease facts and figures. Alzheimer's & dementia: the journal of the Alzheimer's Association, 11(3), 332. The above report focuses on public health and the impacts the Alzheimer’s diseases (AD), it includes all the incidences and the prevailing mortality rates. It also covers cost incurred for caring and also the effect felt by the care givers and the society at large. This report focuses the issues encountered by the health care providers as they try to disclose the AD diagnosis to the patients as well as the care givers. Approximately 5.29 million Americans are diagnosed with AD; 200,000 have an
  • 3. average of below 65 years and 5.1 million are about 65 years. In the U.S. someone will develop AD after every 67 seconds. The expectations are that by 2050, AD will develop after every 33 seconds which will result to nearly a million cases per year. Ad is the sixth leading cause of death in the U.S. disclosure of the AD is usually too hard for the health specialists. Improvement of the disclosure process is supposed to be improved. This article will be useful as I develop my paper since it is much elaborate on the issue of the AD and also gives the statistics on the rate of the infection and so it verses me with the required information to develop an elaborate paper. Bird, T. D. (2015). Alzheimer disease overview According to the above reference, the characteristic of AD is Dementia which typically starts with a subtle as well as memory failure which in turn become incapacitating. There are also other r common findings which include poor judgment, confusion, agitation, language disturbance as well as hallucinations. Sometimes seizures are experienced, increased muscle tones, incontinence, myoclonus and mutism also occurs. Death is caused by malnutrition, pneumonia and general inanition. The recommended clinic duration is usually between 8 to 10 years. As we note from the above reference, the disease is explained in details and this gives me the knowledge of the characteristics of the disease and also the characteristics. This is very important in my paper since it provides me with the best knowledge on the characteristics and the symptoms of the disease. Kumar, A., & Singh, A. (2015). A review on Alzheimer's disease pathophysiology and its management: an update. Pharmacological Reports, 67(2), 195-203. According to Anil Kumar AD disease is known to be a neurodegenerative disorder that is multifarious and progressive. He further explains that this disease is the major cause of Dementia especially in the late adult life. According to pathology, AD is usually characterized by the intracellular tangle of neurofibrillary and also the deposits of the
  • 4. extracellular amyloidal proteins that bring about plaques of senile. The advancing study of pathogenesis has inspired the investigation of therapeutic study towards the pathophysiological events. The reference explains deeply about AD and also mentions the diseases major cause. The information provided is helpful in my paper since it gives details of the cause of AD. Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., ... & Cooper, C. (2017). Dementia prevention, intervention, and care. The Lancet, 390(10113), 2673-2734. In the paper above, Gill and his counterparts tackle the issue about the safety measures to be taken. They say that acting now on ways to prevent AD and intervene as well as exercising care to the infected can largely improve the living. Cases of death will be minimal due to the presence of a vast knowledge about the disease. The lives of people leaving with dementia and their families will improve and by so doing this will significantly bring a transformation to the future of the society. This reference gives the details on how we are supposed to handle the situation of people living with dementia. This knowledge is of much significance to my paper because as much as I will discuss the dementia disease, I will also need to talk about how to live with the infected. Nelson, L., & Tabet, N. (2015). Slowing the progression of Alzheimer’s disease; what works?. Ageing research reviews, 23, 193-209. In this reference, Lucy and Naji explain that Alzheimer’s disease is a disease associated with age and dementia progresses with the age and it is increasing worldwide. It typically affects the short term memory as it onsets. This illness which is devastating advances until it brings impaireness to all the aspects associated with cognitive and the non-cognitive domain too. Nowadays a lot of effort has been put in place a disease modifying treatment or medication but the most promising get faltered during the preclinical research. Because of that failure
  • 5. to get an effective medication, the all the efforts have been shifted to gaining insight on the preventive measures. The authors of this reference explain the efforts that are put in place in order to counter the problem of the increasing disease. Robinson, L., Tang, E., & Taylor, J. P. (2015). Dementia: timely diagnosis and early intervention. Bmj, 350, h3029 Robinson, Tang and Taylor explain their efforts for searching for articles thro Medline, coochrane as well as the pub med and also did research of the available systematic reviews from 2006 all the way to 2014. They talked about pharmacologic treatment as well as the non-pharmacologic treatment. They further explain strategies/interventions and treatment. They also focus on systematic reviews and the Meta analysis and the high quality randomized trials based on control. The authors also include the expected figures of who will have dementia in the future. They further explain the cause of delayed diagnosis. Such information is of much help to me as I develop and advance in writing may paper which should be detailed. Rosenberg, P. B., Nowrangi, M. A., & Lyketsos, C. G. (2015). Neuropsychiatric symptoms in Alzheimer's disease: what might be associated brain circuits?. Molecular aspects of medicine, 43, 25-37. According to the above researchers, Neuropsychiatric symptoms (NPS) are usually very common in the AD disease in particular, apathy, agitation, delusions and depressions. All the brain networks or the circuits where these symptoms underlie are now trying to be understood. The growing neurochemical evidence together with imaging form a base to the understanding of the potential mechanisms of the Neuropsychiatric symptoms (NPS). The authors also offer review of the recent literature and even an hypotheses concerning networks or the circuit’s which underlie these NPS in particular the apathy, agitation and even the delusions. This informationis found in details as we continue analyzing the book. It gives a clear outline on NPS symptoms common in the AD.
  • 6. Stokes, G. (2017). Challenging behavior in dementia: a person- centred approach. Routledge. Graham stokes explains how he never intended to work in the field of dementia. He thought that this could be as a result of lack of ambition or due to poor judgment. He was attracted to neuropsychology and also to research on management of dementia. He says that all the people that spent time with those infected by dementia should be appreciated. He says that working with the people whose memories are failing should be appreciated. He further explains the need to manage the rapidly ensuing problem. The main purpose of his book is to rapidly communicate about the expanding knowledge of the psychology the Dementia disease. This information is good for my paper since it gets me to know more about the psychology of the disease. Winblad, B., Amouyel, P., Andrieu, S., Ballard, C., Brayne, C., Brodaty, H., ... & Fratiglioni, L. (2016). Defeating Alzheimer's disease and other dementias: a priority for European science and society. The Lancet Neurology, 15(5), 455-532. Winblad and his team in this book explain that Alzheimer’s disease (AD) tops the list of causing Dementia. They further state that dementia increases with an increase in the age globally. This disease affects even the wealthier countries and the medical care cost is usually a burden since the numbers of Dementia infections increase overwhelmingly since almost everybody is living into old age. They explain the effort of the government and the policy makers as they make incentives that provide more resources to develop AD therapeutics. This shows that it is a national disaster and a threat to everyone. Zhao, Q. F., Tan, L., Wang, H. F., Jiang, T., Tan, M. S., Tan, L., ... & Yu, J. T. (2016). The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta- analysis. Journal of affective disorders, 190, 264-271. Finally Zhao and his team explain that (NPS)
  • 7. symptoms are progressively recognized as a common serious problem in the AD disease. They further say that the data provided on the prevalence of NPS in the people with AD do conflict with the meta- analysis that is aimed at to approximate the prevalence of the NPS. All the above information is necessary in the development of my paper since it will be much detailed and it will discuss and touch on every bit concerning the AD disease. Alesix Tieku Gero 302 (6381) Topic: Dementia (Alzheimer's Disease) References Alzheimer’s, A. (2015). 2015 Alzheimer's disease facts and figures. Alzheimer's & dementia: the journal of the Alzheimer's Association, 11(3), 332. Bird, T. D. (2015). Alzheimer disease overview. Kumar, A., & Singh, A. (2015). A review on Alzheimer's disease pathophysiology and its management: an update. Pharmacological Reports, 67(2), 195-203. Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., ... & Cooper, C. (2017). Dementia prevention, intervention, and care. The Lancet, 390(10113), 2673-2734. Nelson, L., & Tabet, N. (2015). Slowing the progression of Alzheimer’s disease; what works?. Ageing research reviews, 23, 193-209. Robinson, L., Tang, E., & Taylor, J. P. (2015). Dementia: timely diagnosis and early intervention. Bmj, 350, h3029.
  • 8. Rosenberg, P. B., Nowrangi, M. A., & Lyketsos, C. G. (2015). Neuropsychiatric symptoms in Alzheimer's disease: what might be associated brain circuits?. Molecular aspects of medicine, 43, 25-37. Stokes, G. (2017). Challenging behaviour in dementia: a person- centred approach. Routledge. Winblad, B., Amouyel, P., Andrieu, S., Ballard, C., Brayne, C., Brodaty, H., ... & Fratiglioni, L. (2016). Defeating Alzheimer's disease and other dementias: a priority for European science and society. The Lancet Neurology, 15(5), 455-532. Zhao, Q. F., Tan, L., Wang, H. F., Jiang, T., Tan, M. S., Tan, L., ... & Yu, J. T. (2016). The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta- analysis. Journal of affective disorders, 190, 264-271. Alesix Tieku Topic Selection Dementia There are various types of Dementia i.e. Alzheimer’s disease, vascular dementia, dementia with Lewy bodies (DLB), Huntington Disease, Parkinson Disease Dementia and mixed dementia and lots more. I will be focusing on Alzheimer’s Disease, causes and symptoms, treatment and diagnosis. Alzheimer's is a disease that robs people of their memory. At first, people have a hard time remembering recent events, though they might easily recall things that happened years ago. The HOPE for Alzheimer’s Act (S. 857 /H.R. 1559): Passage of this bill would provide comprehensive care planning services— for both the individual and his/her caregiver— following a dementia diagnosis. Michael Splaine, a long-time advocate and principal of Splaine Consulting, a healthcare policy firm that specializes in Alzheimer’s issues
  • 9. External link disclaimer , is optimistic about the HOPE Act—as the bill is supported by nearly half of the Senate and boasts over 200 House co- sponsors. The National Alzheimer’s Plan is essentially a call to public preparedness for addressing Alzheimer’s, with Goal 3 of the Plan focused on caregiver support. Many advocates are voicing the need for state Alzheimer’s plans too. The Alzheimer’s Caregiver Support Act (H.R. 3090 External link disclaimer ) will provide grants to public and non-profit organizations to expand and improve training and support services for families and caregivers of individuals with Alzheimer’s disease. The RAISE Family Caregivers Act of 2015 (H.R. 3099/S.1719 External link disclaimer ) would facilitate the establishment of a national strategy to address the many issues facing caregivers today, including education and training, long-term services and supports, and financial stability and security. References: https://currents.greatcall.com/categories/news-policy/whats- happening-in-alzheimers-policy-and-why-it-matters/ 1. Albania 2. Algeria 3. Andorra * 4. Argentina 5. Armenia 6. Belarus 7. Bosnia & Herzegovina 8. Burkina Faso * 9. Chad 10. Djibouti *
  • 10. 11. Gabon * 12. Guatemala 13. Indonesia 14. Iran 15. Lesotho * 16. Macedonia 17. Malawi * 18. Mali 19. Mongolia 20. Morocco 21. Nauru * 22. Niger 23. Niue 24. Papua New Guinea * 25. Seychelles * 26. Sierra Leone 27. Sri Lanka 28. Suriname 29. Yemen 30. Zimbabwe * MAT-144 Major Assignment #3 Details Overview: You and some of your friends want to travel to another country to provide aid in the form of a mission trip. You have been chosen as the team leader, and your job is to provide a plan for the trip, including a financial plan. This is a big job, and you want to do it right, so you and your team have agreed that the trip will take place 5 years from now. Requirements for the trip: Who: You and 5-10 other individuals will travel to provide aid. When: 5 years in the future. The trip will last 2-4 weeks. This is not a large scale, so you should think carefully about what you can accomplish with a team of this size and time frame. What: This trip’s main purpose will be to fill some sort of tangible need to improve the day-to-day life of the people you
  • 11. meet. Therefore, your first job will be to decide what your team has to offer and to find a location where there is a need for your talents. You should think about what you can do to alleviate human suffering by working in an area of education, health care, basic supplies (such as clothing or home goods), housing, food or clean water, or work to repair the local environment. If you want to include evangelism as a secondary goal, that is fine, but the criteria you will be graded on is how you make a difference in the day-to-day lives of the people you work with. Where: You will travel overseas. To keep your project manageable, you must choose one of the locations on the Country List, which is included as an attachment to this assignment. Because of the size of the team and your time frame, you should narrow down your area within the country to fit your project. For example, you can’t expect to provide vaccines to the entire country of Brazil, but you could reasonably expect to provide this service to a small town in the country. So you will need to find an area within your chosen country to focus on. The people that you serve in this area are members of your target population.Requirements for the assignment: This assignment will have two parts. Part 1: You create a PowerPoint presentation describing the trip and explaining why the specific country has been chosen. The presentation should have a minimum of eight slides – a title slide, one for each category below, and a reference slide. All important information should be on the face of the slides but you can submit speaker notes for greater detail. In addition, you will need a minimum of three scholarly resources (see the resource list below for ideas) and the presentation should address the following areas: 1. An overview of your purpose for the project: Where are going, and what service will you be providing? Remember, evangelism cannot be the sole purpose of your trip or even the primary purpose. 2. Cultural and social aspects of the country and its population
  • 12. that led you to choose this area of the world. 3. How your choice of project works toward fulfillment of the Judeo-Christian-Islamic ideal to love your neighbor as yourself: How does your personal worldview and the possible worldviews of your target population influence your plans for the trip? 4. Information about your target population: Who are you planning to serve? How does this population compare to the population of the country as a whole? You will also need to do a calculation to project either the general or the target population in 5 years in the spreadsheet but it does not need to be discussed in the presentation. The World Factbook provides population growth data to help you here. 5. Information about the economic situation in your country and how your project will improve this. 6. Possible concerns that you need to keep in mind to keep your team and your target population safe. This could be safety from violence or from health problems (for example, will your team need inoculations to travel to the country). Part 2: A financial plan for your trip, which you will include in the provided Excel spreadsheet. Your financial plan needs to include the following information: 1. A list of expenses for all members of your trip. This must include the following: a. Travel expenses, such as plane or bus fare, passports/visas, local travel within the country. Plane fare can be in U.S. dollars, but the local travel will need to be in the local currency of the country you visit. b. Lodging expenses. If you plan to camp, you will include expenses for your camping gear. If you are planning to stay with a host church or host family, you should research the cost of lodging in your target area and provide a per diem donation that is commensurate with the local lodging rates. This will be in the local currency. c. Food expenses while you are overseas. Again, if you are being fed by local residents, you will research the approximate cost to feed your group and provide a per diem donation to
  • 13. cover expenses. One way to do this is to research cost of living in your country to find out what a local family would expect to budget to pay for food. Again, these costs will be in the local currency. d. Supplies for your project. Provide at least four items that you will need to complete your project. Depending on the nature of your project, these might be in U.S. dollars, or in the local currency, or they may be a mix. e. For your expenses that are given in the local currency, a conversion to U.S. dollars. f. For each expense, you will use the CPI data from the Bureau of Labor Statistics to calculate your estimated expense 5 years in the future. g. A grand total of all projected expenses 5 years from now. 2. Funding sources for your trip. a. Sponsorship: You are going to assume that you can find a sponsor who can provide 30% of your grand total of all expenses for seed money, and you will invest that money in a savings account for the next 5 years. Research current savings rates and calculate what this amount will grow to over the next 5 years. b. Savings: Your team will work on various fundraisers to save for the trip, and you estimate that you can raise $100 a month every month over the next 5 years, which you will also put into a savings account. Using the savings rates you found in part a., calculate what these regular savings amounts will grow to over the next 5 years. c. Loan: If your sponsorship and savings totals do not cover your expenses, then you will need to take out a loan for the remainder of your expenses. Even if your sponsorship and savings total do cover all expenses, then you will take out a $10,000 loan for an additional emergency cushion. Research loan rates from two banks, and calculate the monthly payment, total that you pay back to the bank and total interest you will pay for each loan. You will indicate in the spreadsheet which of the two loans is a better choice for you and your reasons
  • 14. why.Resources You should plan to use the following resources to help you with your plan. You can also use other resources, but at a minimum, you will need the Excel Budget Spreadsheet, BLS CPI data, and CIA World Factbook. Additionally, your paper requires three scholarly sources. · Country list.docx: Includes the list of countries you are allowed to choose from for this project, along with some important facts about the country’s make up. · Bureau of Labor Statistics Consumer Price Data information: https://data.bls.gov/cgi-bin/surveymost?cu which is the same as on Worksheet 2. · CIA World Fact Book: You must use this source. You will find that it contains a wealth of demographic, economic, and cultural information about your country. https://www.cia.gov/library/publications/the-world-factbook/ · U.S. Department of State website: This site will give you important information about your country, as well as information about travel overseas. https://travel.state.gov/content/travel/en/international- travel/International-Travel-Country-Information-Pages.html · Excel Budget Spreadsheet: Attached to the assignment directions, and provides a compact way to explain your budget and funding. · Your course textbook · GCU LibraryTips and formulas: · This assignment uses a rubric. Please be sure to look at the grading criteria and point values for each area of the rubric to see how you will be graded on this assignment. · Compound interest formula (also called the Lump Sum Investment formula) formatted for EXCEL: A = P * ((1 + r/n)^(n * t). · A is the accrued amount after t years that the principal, P, grows to at interest rate, r%, compounded n times each year. · Regular payments formula (also called the Savings Plan formula) formatted for EXCEL: A = PMT * ((1 + r/n)^(n * t)-
  • 15. 1)/(r/n). · A is the accrued amount after t years of making regular payments, PMT, into an account at interest rate, r%, compounded n times each year. · Loan payment formula formatted for EXCEL: PMT = P * (r/n)/(1 – (1 + r/n)^(-n*t)). · PMT is the payment required to pay off a loan of $P at interest rate, r%, compounded n times per year for t years. · Percent change IR = (new CPI – old CPI)/old CPI where IR is inflation rate.