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Transcription
     By: Tucker Jenary
Transcription is the first step in protein synthesis. It
all happens in the nucleus. First, the DNA strand is
split by RNA polymerase. While RNA polymerase
splits the DNA, the mRNA strand is formed.
Then, the correct nucleotide is matched on the
mRNA strand to the DNA strand. This continues until
it reaches the stop codon. Then, the mRNA strand is
complete. The final step is when the mRNA strand
goes through the nuclear pore and enters the
cytoplasm. This is where the process of translation
begins.
Nucleus
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




              DNA Strand
(Inside the Nucleus)
        Adenine
        Thymine
        Guanine
        Cytosine




erase




                      DNA Strand
(Inside the Nucleus)
           Adenine
           Thymine
           Guanine
           Cytosine




 A
lymerase




                         DNA Strand
(Inside the Nucleus)
             Adenine
             Thymine
             Guanine
             Cytosine




RNA
Polymerase




                           DNA Strand
(Inside the Nucleus)
             Adenine
             Thymine
             Guanine
             Cytosine




RNA
Polymerase




                           DNA Strand
(Inside the Nucleus)
             Adenine
             Thymine
             Guanine
             Cytosine




RNA
Polymerase




                           DNA Strand
(Inside the Nucleus)
       Adenine
       Thymine
       Guanine
       Cytosine




RNA
Polymerase




                     DNA Strand
(Inside the Nucleus)
    Adenine
    Thymine
    Guanine
    Cytosine




RNA
Polymerase




                  DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




RNA
Polymerase




                DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




   RNA
   Polymerase




                   DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




      RNA
      Polymerase




                      DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




           RNA
           Polymerase




                           DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




           RNA
           Polymerase




                           DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




           RNA
           Polymerase




                        DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




           RNA
           Polymerase




                    DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




           RNA
           Polymerase




                DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




             RNA
             Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




               RNA
               Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                   RNA
                   Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                       RNA
                       Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                           RNA
                           Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                             RNA
                             Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymerase




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polymeras




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




                                  RNA
                                  Polyme




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




              DNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine




              DNA Strand
(Inside the Nucleus)
           Adenine
           Thymine
           Guanine
           Cytosine



                      DNA Strand




Promoter                   Coding Region      Termination
                                              Sequence
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
             DNA Strand (split by RNA polymerase)
(Inside the Nucleus)
         Adenine
         Thymine
         Guanine
         Cytosine
          Uracil
                      DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
      Adenine
      Thymine
      Guanine
      Cytosine
       Uracil
                   DNA Strand (split by RNA polymerase)




mRNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil
                         DNA Strand (split by RNA polymerase)




           mRNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil
                         DNA Strand (split by RNA polymerase)




           mRNA Strand
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil
                         DNA Strand (split by RNA polymerase)




           mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                                       DNA Strand (split by RNA polymerase)




Start Codon              mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                             DNA Strand (split by RNA polymerase)




Start Codon              mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                             DNA Strand (split by RNA polymerase)




Start Codon              mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                             DNA Strand (split by RNA polymerase)




Start Codon              mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                             DNA Strand (split by RNA polymerase)




Start Codon              mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                             DNA Strand (split by RNA polymerase)




Start Codon              mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                             DNA Strand (split by RNA polymerase)




Start Codon              mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                 mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                 mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                 mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                 mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                 mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                 mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




Start Codon                                               mRNA Strand
(Inside the Nucleus)
              Adenine
              Thymine
              Guanine
              Cytosine
              Uracil
                           DNA Strand (split by RNA polymerase)




                                     mRNA Strand
Start Codon                                                       Stop Codon
(Inside the Nucleus)
           Adenine
           Thymine
           Guanine
           Cytosine
           Uracil




                               mRNA Strand
rt Codon                                     Stop Codon

                                                  Nuclear Pore
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil




                           mRNA Strand


                                         Nuclear Pore
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil




                                  mRNA Strand


                                                Nuclear Pore
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil




                                  mRNA Strand


                                        Nuclear Pore
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil




                                  Nuclear Pore
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil




                                  Nuclear Pore
(Inside the Nucleus)
Adenine
Thymine
Guanine
Cytosine
Uracil




                                  Nuclear Pore
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




                             mRNA Strand




           mRNA strand leaves nucleus and
           enters the cytoplasm
Translation
Translation is the process that is used to form proteins.
The mRNA strand enters the cytoplasm from the nucleus.
Then, the ribosome attaches to the mRNA strand and
starts to read the mRNA strand. The tRNA then comes in
with the amino acids and matches the mRNA strand with
the complementary base. Then, this continues down the
mRNA strand until it reaches the stop codon. The tRNA
falls off as the ribosome goes down the strand and it
leaves its amino acids. The next tRNA’s amino acid
attaches to the other amino acid by a peptide bond.
Once the ribosome gets to the stop codon, it stops and
the last tRNA falls off leaving all of the amino acids. The
amino acids from into a 3-D structure which forms the
complete protein.
Cytoplasm
Adenine
                                Ribosome
Thymine
Guanine
Cytosine
Uracil




                  mRNA Strand
Cytoplasm
           Adenine
           Thymine
           Guanine
           Cytosine
            Uracil




                                                  mRNA Strand
Ribosome




                      Codon      Codon    Codon      Codon   Codon   Codon   Codon   Stop
Start      Codon                                                                     Codon
Codon
                         Ribosome in cytoplasm attaches to mRNA
                         strand to start reading each codon. It
                         knows to start there because of the start
                         codon.
Cytoplasm
                Adenine
                Thymine
                Guanine
                Cytosine
                Uracil




                                               mRNA Strand
Ribosome




           tRNA then comes to match the
           codon with the correct nucleotide
Cytoplasm
 Adenine
 Thymine
 Guanine
 Cytosine
 Uracil




                                 mRNA Strand
Ribosome




 Peptide Bond joins the amino acids
Cytoplasm
 Adenine
 Thymine
 Guanine
 Cytosine
 Uracil




                                      mRNA Strand
Ribosome




           As the ribosome continues reading
           down the mRNA strand, the tRNA
           falls off leaving the amino acid.
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




                             mRNA Strand
           Ribosome
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




                             mRNA Strand
           Ribosome
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




                        mRNA Strand
             Ribosome
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




           mRNA Strand
                             Ribosome
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




           mRNA Strand
                             Ribosome
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




           mRNA Strand
                             Ribosome
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




           mRNA Strand
                             Ribosome
Cytoplasm
Adenine
Thymine
Guanine
Cytosine
Uracil




           mRNA Strand
                             Ribosome
Cytoplasm
Adenine
Thymine
Guanine        The last tRNA falls leaving its
                                                 Ribosome
Cytosine       amino acid behind. Also, the
Uracil         ribosome falls off of the
               mRNA strand.


           mRNA Strand
Cytoplasm



The amino acid chain folds up into a
3-D structure that is dictated by the
order of the amino acids. Then, the
protein is formed.




                          Completed Protein

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