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Protein synthesisDevonDubensky

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Protein synthesisDevonDubensky

  1. 1. Cell Nucleus
  2. 2. Cell Nucleus
  3. 3. Cell Nucleus
  4. 4. T A A T C C A C C T T G T A G G T A G A C A T G T A A A T T
  5. 5. A U mRNA strand G C A T A U T A A T C C A C C T T G T A G G T A G A A T T G A Promoter Region T RNA polymerase
  6. 6. A U mRNA strand G A A U G U A G C T A C A T T C A T A U C A C T G T G A RNA polymerase G A T G T A A T T G A
  7. 7. A U mRNA strand G A A U G U A G G T G C U A C C T A C A T T C A T A U A RNA polymerase A G T G G A T G T A T T G T A
  8. 8. T C C A C T T A G G T G A G T A A C A T T A A G A C T T A T A U G mRNA strand U A A U G U A G G RNA polymerase U G
  9. 9. Nucleus A U mRNA strand G U A A U Nuclear pore G U A G G U G A
  10. 10. Stop codon A A G T G Codon G T Codon G T A Codon T T G T A Start codon
  11. 11. Large subunit Ribosome Stop codon A G T G Codon G T Codon G T A Codon T T G T A Start codon A Small subunit
  12. 12. Amino Acid Large subunit tRNA Ribosome C Stop codon A A G T G Codon G T Codon G T A Codon T G T T A A U Start codon Small subunit
  13. 13. Large subunit tRNA tRNA Ribosome U Stop codon A A G T G Codon G T Codon G T A Codon T G A C T T A A A U Start codon Small subunit
  14. 14. tRNA Large subunit tRNA Ribosome Stop codon A A G T G Codon G T G T Codon A C A A T T Codon U A A G T A Start codon Small subunit
  15. 15. Large subunit tRNA tRNA Ribosome C C U A C A U A A C A U Stop codon A G T G Codon G T Codon G T A Codon T T G T A Start codon A Small subunit
  16. 16. Large subunit tRNA tRNA Ribosome C C U Stop codon A G T G Codon G T Codon G T A Codon T T G T A Start codon A Small subunit
  17. 17. Polypeptide bond A A G T Stop codon U C A G G Codon C C U T G T A Codon A C A U Codon T G A C T T A A A U Start codon
  18. 18. Summary Transcription begins in the cell nucleus when RNA polymerase breaks apart the DNA strand and then makes mRNA strand. After the RNA polymerase breaks apart the strand, it will reform the hydrogen bonds. As the RNA polymerase is going through the strand, it will synthesis the top strand. Thymine is now replaced with uracil. So now, Adenine and uracil pair together and guanine and cytosine pair together. Once the RNA polymerase reaches the termination sequence it breaks off and the mRNA strand goes out of the nucleus through a nuclear pore. That will end the process of transcription. To begin translation in the cytoplasm, the bottom strand of the original DNA strand will be put into groups of three called codons. The first group is called the start codon and will always be the letters TGA and the start codon is the last group of three which can be paired in three different ways. A ribosome with a large subunit and a small subunit will come and bring a tRNA molecule which will bring the anti codons down to the strand with an amino acid. As the third tRNA molecule comes, the one in the front will fall off leaving only the amino acid. As this process continues, once it reaches the stop codon, there will not be a tRNA molecule for the stop codon, it will just stop and what will be left will be the polypeptide bond. The final protein in its tertiary structure is the single polypeptide chain also known as the backbone with one or more protein secondary structures.

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