Anti Ageing Treatment with stem cells

SKIN, FACE REJUVENATION
AND
HAIR RESTORATION
Website : www.stemgenn.com | Email : Contact@stemgenn.com | Phone : +91 9811011690

Hair loss
Development of fine lines and
wrinkles, itchy or dry skin
Sagging skin from loss of underlying
fat or bone mass
Development of spider and
varicose veins and
Thinning or
transparent skin
DAUNTING DREAMS
OF OLD AGE

ADSCs AND PRP
PRP (Platelet Rich Plasma) and Adipose Derived Stem
Cells (ADSCs) are revolutionary techniques which are
allowing rejuvenation of the skin, face and hair
restoration using the patient’s own (autologous) cells,
with long lasting effects.

VAMPIRE FACE LIFT
PRP is a concentrated blood sample that contains
high levels of platelets, a critical component of
the wound healing process.
Platelets contain growth factors that
are responsible for stimulating tissue
generation and repair. Growth factors
derived from platelets are responsible
for soft tissue repair, hair growth,
development of new blood vessels, and
stimulation of the wound healing
process.

WHY PLATELETS
Vascular endothelial growth factor (VEGF)
Growth and new generation of vascular endothelial cells. Significant
mediator of hair follicle growth and cycling, providing the first direct
evidence that improved follicle vascularisation promotes hair growth,
as well as increasing follicle and hair size.
Platelet-derived growth factor (PDGF)
Cell growth, new generation and repair of Blood
vessels, collagen production. PDGF is a required element in
cellular division for fibroblasts, a type of connective tissue
cell that is especially prevalent in wound healing.
Transforming Growth Factors (TGF a and b)
Growth and neogenesis of epithelial cells
and vascular endothelial cells, promotion
of wound healing.
Favours the synthesis of collagen.
Epidermal growth factor (EGF)
Stimulates cell growth, proliferation, and
differentiation of epidermis cell.
It effect on the proliferation of basal
keratinocytes and of cells that comprise
the outer root sheath of hair.
Insulin-like growth factor 1 (IGF-1)
Regulates the expression of a powerful
messenger cellular level, which is anti-
apoptotic and capable of preventing
the cell death.
Fibroblast growth factor (FGF)
Tissue repair, cell growth, collagen
production, hyaluronic acid production
PLATELETS

PRP PROCEDURE
Speed and duration of
centrifugation is very
important to ensure the
platelets are not damaged
Patient
autologous
(own)cell
Centrifuged the
blood
Before PRP
After PRP
Before PRP
After PRP

RESULTS OF PRP
Also Includes
Stimulating hair growth
Decreasing facial rhytids
Enhancing the taking
rate of fat transplant
stimulate collagen production
in the subcutaneous tissues
when used as a filler (alone or
combined with collagen or
hyaluronic acid
 Decreasing hematoma/seroma post rhytidectomy,
 Improving the appearance of stretch marks and scars (alone or in
combination with laser).

ADVANTAGES OF PRP
Promotes local tissue growth and repair.
Patient’s safety – patient’s own blood, therefore
no disease transmission, non toxic and no
rejection.
Conveniently PRP prepared at doctor’s office.
Faster healing- platelets accelerate tissue
synthesis.
Cost effectiveness- no need for external
substances.
Simple and easy to use.

ADIPOSE DERIVED
STEM CELLS
Human adipose tissues that contain Adipose-derived stem cells (ADSCs) are one
of the latest scientific breakthroughs in the field of aesthetic surgery.
ADSCs are easily isolated from fat tissue harvest by liposuction, and they can
differentiate into several types of lineages in culture.
ADSCs are likely to be pluripotent Mesenchymal Stem cells (MSCs), which share
similar characteristics with Bone marrow Stem cells (BMSCs).
ADSCs have paracrine effects on their surrounding environment through the
secretion of many growth factors, such as vascular endothelial growth factor
(VEGF), hepatocyte growth factor (HGF), basic fibroblast growth factor (bFGF),
platelet-derived growth factor (PDGF), keratinocyte growth factor (KGF),
transforming growth factor (TGF)-E1, insulin-like growth factor-binding protein (IGF-
BP) precursors, fibronectin, and superoxide dismutase (SOD).
These proteins secreted by ADSCs exert diverse hair growth, skin-rejuvenating
effects, such as the stimulation of collagen synthesis and fibroblast migration
during wound healing.

ADSCs PROCEDURE
Adipose tissue aspiration
from patient
Isolation of ADSCs
Concentration of
ADSCs
Before ADSCs After ADSCs
Before ADSCs After ADSCs
Injection of
ADSCs in patient

RESULTS OF ADSCs
Hair growth

ADVANTAGES OF
ADSCs
Long-term stability.
Lyophilized ADSC-CM avoids most of the
safety issues.
Use of ADSC may also enhance the scalability
of production, low-cost therapeutics.

FACTS ABOUT
ADSCs & PRP
“Stem cells have a
mystique—they’re
chameleon-like cells that
are thought to be able to
make skin look fresh and
young,” says Erin Gilbert, a
leading dermatologist from
New
York
Notable celebrities such as
Reese Witherspoon, Madonna,
Jacqueline Bisset, J.lo and
even Marc Anthony reportedly
use stem cell treatments as
part of their skin rejuvenation.

StemGenn Therapeutics is a leading Cell
therapy & Regenerative medicine services
company that supports the development and
commercialization of cellular therapies and
stem cell research

• As Stem cell have inherent properties to self renew and
differentiation into other cell types. They are multi potent
and found within our body.
• No side effects: As it's found in patient's own tissues or blood
chances of rejection and infection is negligible.
• World class clinicians and experts from Regenerative Medicine.
• Cost Effectiveness: Autologous stem cell transplant is very much
affordable.
• Non- Surgical Procedure & convenient.
• Proven Results.

Richa Jha
Managing Director, Founder
Prabhu Mishra
President, CEO, Co-Founder
– ‘Secretary General- Stem Cell
Society, India.’
Shreyashi Gangopadhyay
Director, Business Development & Project
Management

Dr. Sharda Jain
MD, MANMS,
FICOG, FIMSA, DHM, QM & AHO,
Secretary General – Delhi Gynae
Forum
Dr Harinder Singh Bedi
MCh, Director Cardio Vascular,
CMC Ludhiana
Dr Satish Totey
PhD, More than 35 yr work
experience in Stem Cell Research
Dr. Roopam Jain
MBBS,DCP, MD, DNB
(Immunohematology & Transfusion
Med) ,Ass. Proff.RD Gardi Medical college
Dr. Rahul Bhargava
MBBS, MD, DM, Post DM Fellowship,
Bone Marrow Transplant Specialist

BLOOD RELATED DISEASES: Thalssemia, Sickle Cell Anemia,
Aplastic Anemia.
1
2 AUTOIMMUNE DISEASES: Type 1 Diabetes, Rheumatoid Arthritis,
Chronic Disease, Multiple Sclerosis, Myasthenia Gravis, Ankylosing
Spondylitis, COPD, ILD.
3 NEUROLOGICAL DISORDERS: Cerebral Palsy, Stroke, Spinal
Cord Injury, Cerebral Atrophy, Muscular Dystrophy, Autism, Multiple
Sclerosis, ALS.
4 ORTHOPAEDIC DISEASE: Avascular Necrosis, Osteoarthritis, Non
Union Fracture, Chondromalacia Patallae, Sport Injury.
5 LIFESTYLE DISEASES: Diabetes, Liver Cirrhosis, Chronic Kidney,
disease, Erectile Dysfunction, Anti - Aging.
6 STEM CELL CONSULTING AND TRAINING PROGRAM:
Regenerative Medicine Lab Setup, Cord Blood Bank Set Up, Regulatory
and Scientific Support.

StemGenn Therapeutics is key
segment………….

Mita
Stem cell in cosmetics is future.
Mona
Ashutosh
Stem cell treatment is really great, after treatment
my skin is glowing & fine lines is gone. Thanks to
StemGenn stem cell treatment is wonderful &
worth of money .
StemGenn training program is excellent.

Deepika (Dietician)
My Skin is also glowing. Its really magic;
Pigmentation is not all visible.
Dr. Shaloo Gupta
Dr. Ruby Srivastava
StemGenn anti ageing treatment provides prolonged
effect.Skin is glowing and feeling wonderful. When
do we get our supply of magic glow.
StemGenn anti ageing treatment is amazing
treatment. Glow came and fine lines
minimised.

REFERENCES
http://barefacedtruth.com/how-skin-ages/
European Journal of Dentistry
http://www.harvesttech.com/harvest-prp
http://www.dermnetnz.org/procedures/platelet-rich-plasma.html
Minimally Invasive Procedures for Facial Rejuvenation; Dr. C Giuseppe and Dr. R. Antonio
The American Journal of Cosmetic Surgery Vol. 29, No. 4, 2012
https://en.wikipedia.org/wiki/Epidermal_growth_factor
https://en.wikipedia.org/wiki/Platelet-derived_growth_factor, June 2013; prime-
journal.com; Platelet-Rich Plasma: A Therapy For Hair Growth

Anti Ageing Treatment with stem cells

Anti Ageing Treatment with stem cells

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