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Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277]
www.ijrpp.com
~ 273~
ISSN Print: 2278-2648 IJRPP |Vol.3 | Issue 4 | Oct-Dec-2014
ISSN Online: 2278-2656 Journal Home page: www.ijrpp.com
Research article Open Access
Assessment of level of cognitive impairment among stroke patients
Vyshnavi P.V.*,1
, Sreelekha B.2
1
Faculty of Nursing, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India.
2
Faculty of Nursing, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India.
*Corresponding author: B. Sreelekha
E-mail id: sreelekha_rajesh@rediffmail.com.
ABSTRACT
Background
It was estimated that yearly 20 million people are affected with stroke, among them five million die. Cognitive
impairment occurs in about two third of stroke survivors. Several studies reported that the impaired cognition
hampers the level of patient role in his self-care and also a major determinant of caregivers role.
Method
A descriptive survey was carried out for the present study. The data were collected from 30 patients after explaining
the nature of the study and obtaining informed consent from them. Dr. Patrick Brook’s cognitive impairment test,
which consists of six items, was used to assess the cognitive impairment among the patients.
Results
The results showed that 21 (70%) patients had mild cognitive impairment at the time of discharge and nine (30%)
patients had normal cognitive level.
Conclusion
Assessment of the level of cognitive impairment of stroke patients help the nurses to plan specific nursing
intervention, teach home care management to the care givers focusing on individual patient needs.
Keywords: Cognitive impairment, cerebrovascular accident, stroke
INTRODUCTION
Cerebrovascular accident ranks second in causing
mortality and fourth in causing morbidity throughout
the world. Every year approximately 20 million
suffer from stroke, among that five million people die
[1]. Men are affected with stroke than women [2].
The prevalence of stroke increases with age [4].
Approximately two third of the patients with
cerebrovascular accident experience cognitive
impairment following stroke and about one third
develop dementia. Recovery from cognitive
impairment occurs mostly with in the first three
months of post stroke period whereas it may extend.
It was estimated that nearly half of the stroke
survivors had some degree of physical and cognitive
impairment [3]. Patients with previous history of
cerebrovascular accident are at major risk for the
development of cognitive impairment and it was also
International Journal of Research in
Pharmacology & Pharmacotherapeutics
Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277]
www.ijrpp.com
~ 274~
associated with the habit of smoking. The study
conducted in India shows that the risk of cognitive
impairment is associated with older age [6].
The main objectives of the study are to
1. Assess the cognitive level of stroke patients.
2. Associate the selected background variables with
the cognitive level of the stroke patients.
MATERIALS AND METHODS
The study was carried out after obtaining approval
from the Institutional Ethics Committee. A
descriptive survey was conducted among 30 patients
who were recovered from stroke.
The sampling criteria include
1. Inclusion criteria
Patients
a. diagnosed with cerebrovascular accident,
transferred from ICU to Neurology ward.
b. diagnosed to have CVA for the first time.
c. between the age group of 36 and 75 years.
d. who could understand Tamil and/or English.
e. both male and female.
2. Exclusion criteria
Patients
a. who had dysarthria.
b. who were not willing to participate in the
study.
The data were collected from the Neurology ward of
a University Teaching Hospital, Chennai. The
purpose of the study was explained and informed
consent was obtained from the patients. The tool used
to assess the cognitive level is Dr. Patrick Brook’s
cognitive impairment test. It consists of six questions
and they are inversely scored and questions are
weighted to make a total score of 28. The reliability
of the tool was 0.8, assessed by using inter rater
method. The interpretation of the score was as
follows: 0-7: probably normal, 8-9: mild cognitive
impairment, 10-28: probably significant cognitive
impairment.
RESULTS
The result showed that 18 (60%) patients were
between the age group of 56-65 years, 20 (66.66%)
patients were male, 08 (26.67%) patients had
secondary education, 7 (23.33%) patients were doing
business, 11 (36.67%) patients had family income of
Rs.10001-15000, 14 (46.67%) patients resides in
semi urban area, 16 (53.33%) had support from their
son/daughter, 24 (80%) patients had no family
history of cerebrovascular accident, 22 (73.33%) had
no previous history of hospitalization and 20
(66.67%) patients had co-morbid illness.
The study revealed that 09 (30%) patients had normal
cognition level and 21 (70%) patients had mild
cognitive impairment at the time of discharge. It also
shows that the association between cognitive level of
the patients at the time of discharge and selected
background variables such as age, gender and co-
morbid illness were statistically significant at the
level of p<0.05.
.
Table1. Frequency and percentage distribution of demographic variables among patients
recovered from cerebrovascular accident (N=30).
Demographic
Variables
No. %
1. Age in years
a. 36-45
b. 46-55
c. 56-65
d. 66-75
00
03
18
09
00
10
60
30
2. Gender
a. Male
b. Female
20
10
66.66
33.34
3. Educational status
a. No formal education
b. Primary school
04
06
13.33
20.00
Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277]
www.ijrpp.com
~ 275~
c. Secondary school
d. Higher secondary
e. Graduate
f. Postgraduate
08
06
04
02
26.67
20.00
13.33
06.67
4. Occupation
a. Homemaker
b. Retired
c. Business
d. Government sector
e. Private sector
08
07
07
03
05
26.67
23.33
23.33
10.00
16.67
5. Family income (Rs per month)
a. <5000
b. 5001-10,000
c. 10,001-15,000
d. >15,000
02
07
11
10
06.67
23.33
36.67
33.33
6. Residence
a. Rural
b. Semi urban
c. Urban
09
14
07
30.00
46.67
23.33
7. Family support
a. Spouse
b. Son/Daughter
c. Others
09
16
05
30.00
53.33
16.67
Table 2. Frequency and percentage distribution of clinical variables among patients
recovered from cerebrovascular accident (N=30).
Clinical
Variables
No. %
1. Family history of cerebrovascular
accident
a. Yes
b. No
06
24
20.00
80.00
2. Previous history of hospitalization
a. Yes
b. No
08
22
26.67
73.33
3. Co-morbid illness
a. Yes
b. No
c. If yes specify:
i. Hypertension
ii. Diabetes mellitus
iii. Hypertension and Diabetes mellitus
20
10
10
02
08
66.67
33.33
33.33
06.67
26.67
Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277]
www.ijrpp.com
~ 276~
Table 3. Frequency and percentage distribution of level of cognitive ability among patients
recovered from cerebrovascular accident.
Level of cognitive ability No. %
Normal 09 30
Mild cognitive impairment 21 70
Significant cognitive impairment 00 00
Table4. Association of selected background variables with the cognitive level among
patients recovered from cerebrovascular accident (N=30).
S.
No.
Background variables Normal
Mild cognitive
impairment
Significant cognitive
impairment
χ 2
and
p
value
No. % No. % No. %
1. 1. Age in years
a. 36-45
b. 46-55
c. 56-65
d. 66-75
01
06
02
03.33
20.00
06.67
02
12
07
06.67
40.00
23.33
00
00
00
00
00
00
5.1
0.05*
2. 2. Gender
a. Male
b. Female
08
01
26.67
03.33
12
09
40.00
30.00
00
00
00
00
2.84
0.032*
3 Family history of
cerebrovascular accident
a. Yes
b. No
05
04
16.67
13.33
01
20
03.33
66.67
00
00
00
00
6.30
0.632
4 Previous history of
hospitalization
a. Yes
b. No
04
03
13.33
10.00
04
19
13.33
63.34
00
00
00
00
4.36
0.613
5 Co-morbid illness
a. Yes
b. No
c. If yes specify:
i. Hypertension
ii. Diabetes mellitus
iii. Hypertension and
Diabetes mellitus
04
05
03
00
01
13.33
16.67
10.00
00
03.33
16
05
07
02
07
53.33
16.67
23.33
06.67
23.33
00
00
00
00
00
00
00
00
00
00
2.84
0.024*
DISCUSSION
The present study showed that 70% of patients had
mild cognitive impairment at the time of discharge,
30% of patients had normal cognitive ability at the
time of discharge and none of them had significant
cognitive impairment.
There is a statistically significant association between
patients’ cognitive level at the time of discharge and
selected background such as age, gender and co-
morbid illness. There is no significant association
between other background variables such as family
history of cerebrovascular accident and previous
history of hospitalization, and patient’s cognitive
level at the time of discharge.
Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277]
www.ijrpp.com
~ 277~
The findings of this study is supported by the study
conducted by Sanjiv K Saxena (2006), the study
revealed that increasing age is one of significant
determinant of cognitive impairment among stroke
patients [5].
It is recommended to conduct the study by comparing
the cognitive impairment at frequent interval from
admission till discharge; the cognitive level of the
patients can be associated previous history of stroke.
CONCLUSION
The study concludes that the level of cognitive
impairment is increased with advanced age, male
gender and with the presence of co-morbid illness.
Nurses should consider these factors and tailor-made
the interventions and home care teaching to ensure
quality patient care.
ACKNOWLEDGEMENT
With deep sense of gratitude I express my special
thanks to the Managing Trustee, SRU, Prof. P.V.
Ramachandran, M.Sc.(N)., chairman, Nursing
Education, Dr.B.Sreelekha, Reader, Dept. of Medical
Surgical Nursing and Faculty members for their
support and guidance. I am grateful to all the patients
for their participation and cooperation throughout the
period of study.
REFERENCES
[1] Dalal P, Bhattacharjee M, Vairale J and Bhat P, UN millennium development goals: can we halt the stroke
epidemic in India? Annals of Indian Academy of Neurology, 10, 2007, 130-6.
[2] Ferri CP, Acosta D, Guerra M, Huang Y and Llibre-Rodriguez JJ, Socioeconomic Factors and All Cause
and Cause-Specific Mortality among Older People in Latin America, India, and China: A Population-Based
Cohort Study. PLoS Med ,2012 9(2): e1001179.
[3] Maya Danovsk, Boyoko Stamenov, Margartia Alexander. Post stroke cognitive impairment-
phenomenological and prognostic factors. Journal of IMAB. 2012.18(3)290-297
[4] Murray J, Young J and Forster A , Developing a primary care-based stroke model: the prevalence of
longer-term problems experienced by patients and carers, British Journal of General Practice, 2003, 53,
803-807.
[5] Saxena, S K. (2006). Prevalence and Correlates of Cognitive Impairment in Stroke Patients in a
rehabilitation Setting. International Journal of Psychosocial Rehabilitation. 10 (2) 37-47.
[6] Young J, Froster A. Review of stroke rehabilitation. British Medical Journal 2007, 334:86-90.

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Assessment of level of cognitive impairment among stroke patients

  • 1. Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277] www.ijrpp.com ~ 273~ ISSN Print: 2278-2648 IJRPP |Vol.3 | Issue 4 | Oct-Dec-2014 ISSN Online: 2278-2656 Journal Home page: www.ijrpp.com Research article Open Access Assessment of level of cognitive impairment among stroke patients Vyshnavi P.V.*,1 , Sreelekha B.2 1 Faculty of Nursing, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India. 2 Faculty of Nursing, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India. *Corresponding author: B. Sreelekha E-mail id: sreelekha_rajesh@rediffmail.com. ABSTRACT Background It was estimated that yearly 20 million people are affected with stroke, among them five million die. Cognitive impairment occurs in about two third of stroke survivors. Several studies reported that the impaired cognition hampers the level of patient role in his self-care and also a major determinant of caregivers role. Method A descriptive survey was carried out for the present study. The data were collected from 30 patients after explaining the nature of the study and obtaining informed consent from them. Dr. Patrick Brook’s cognitive impairment test, which consists of six items, was used to assess the cognitive impairment among the patients. Results The results showed that 21 (70%) patients had mild cognitive impairment at the time of discharge and nine (30%) patients had normal cognitive level. Conclusion Assessment of the level of cognitive impairment of stroke patients help the nurses to plan specific nursing intervention, teach home care management to the care givers focusing on individual patient needs. Keywords: Cognitive impairment, cerebrovascular accident, stroke INTRODUCTION Cerebrovascular accident ranks second in causing mortality and fourth in causing morbidity throughout the world. Every year approximately 20 million suffer from stroke, among that five million people die [1]. Men are affected with stroke than women [2]. The prevalence of stroke increases with age [4]. Approximately two third of the patients with cerebrovascular accident experience cognitive impairment following stroke and about one third develop dementia. Recovery from cognitive impairment occurs mostly with in the first three months of post stroke period whereas it may extend. It was estimated that nearly half of the stroke survivors had some degree of physical and cognitive impairment [3]. Patients with previous history of cerebrovascular accident are at major risk for the development of cognitive impairment and it was also International Journal of Research in Pharmacology & Pharmacotherapeutics
  • 2. Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277] www.ijrpp.com ~ 274~ associated with the habit of smoking. The study conducted in India shows that the risk of cognitive impairment is associated with older age [6]. The main objectives of the study are to 1. Assess the cognitive level of stroke patients. 2. Associate the selected background variables with the cognitive level of the stroke patients. MATERIALS AND METHODS The study was carried out after obtaining approval from the Institutional Ethics Committee. A descriptive survey was conducted among 30 patients who were recovered from stroke. The sampling criteria include 1. Inclusion criteria Patients a. diagnosed with cerebrovascular accident, transferred from ICU to Neurology ward. b. diagnosed to have CVA for the first time. c. between the age group of 36 and 75 years. d. who could understand Tamil and/or English. e. both male and female. 2. Exclusion criteria Patients a. who had dysarthria. b. who were not willing to participate in the study. The data were collected from the Neurology ward of a University Teaching Hospital, Chennai. The purpose of the study was explained and informed consent was obtained from the patients. The tool used to assess the cognitive level is Dr. Patrick Brook’s cognitive impairment test. It consists of six questions and they are inversely scored and questions are weighted to make a total score of 28. The reliability of the tool was 0.8, assessed by using inter rater method. The interpretation of the score was as follows: 0-7: probably normal, 8-9: mild cognitive impairment, 10-28: probably significant cognitive impairment. RESULTS The result showed that 18 (60%) patients were between the age group of 56-65 years, 20 (66.66%) patients were male, 08 (26.67%) patients had secondary education, 7 (23.33%) patients were doing business, 11 (36.67%) patients had family income of Rs.10001-15000, 14 (46.67%) patients resides in semi urban area, 16 (53.33%) had support from their son/daughter, 24 (80%) patients had no family history of cerebrovascular accident, 22 (73.33%) had no previous history of hospitalization and 20 (66.67%) patients had co-morbid illness. The study revealed that 09 (30%) patients had normal cognition level and 21 (70%) patients had mild cognitive impairment at the time of discharge. It also shows that the association between cognitive level of the patients at the time of discharge and selected background variables such as age, gender and co- morbid illness were statistically significant at the level of p<0.05. . Table1. Frequency and percentage distribution of demographic variables among patients recovered from cerebrovascular accident (N=30). Demographic Variables No. % 1. Age in years a. 36-45 b. 46-55 c. 56-65 d. 66-75 00 03 18 09 00 10 60 30 2. Gender a. Male b. Female 20 10 66.66 33.34 3. Educational status a. No formal education b. Primary school 04 06 13.33 20.00
  • 3. Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277] www.ijrpp.com ~ 275~ c. Secondary school d. Higher secondary e. Graduate f. Postgraduate 08 06 04 02 26.67 20.00 13.33 06.67 4. Occupation a. Homemaker b. Retired c. Business d. Government sector e. Private sector 08 07 07 03 05 26.67 23.33 23.33 10.00 16.67 5. Family income (Rs per month) a. <5000 b. 5001-10,000 c. 10,001-15,000 d. >15,000 02 07 11 10 06.67 23.33 36.67 33.33 6. Residence a. Rural b. Semi urban c. Urban 09 14 07 30.00 46.67 23.33 7. Family support a. Spouse b. Son/Daughter c. Others 09 16 05 30.00 53.33 16.67 Table 2. Frequency and percentage distribution of clinical variables among patients recovered from cerebrovascular accident (N=30). Clinical Variables No. % 1. Family history of cerebrovascular accident a. Yes b. No 06 24 20.00 80.00 2. Previous history of hospitalization a. Yes b. No 08 22 26.67 73.33 3. Co-morbid illness a. Yes b. No c. If yes specify: i. Hypertension ii. Diabetes mellitus iii. Hypertension and Diabetes mellitus 20 10 10 02 08 66.67 33.33 33.33 06.67 26.67
  • 4. Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277] www.ijrpp.com ~ 276~ Table 3. Frequency and percentage distribution of level of cognitive ability among patients recovered from cerebrovascular accident. Level of cognitive ability No. % Normal 09 30 Mild cognitive impairment 21 70 Significant cognitive impairment 00 00 Table4. Association of selected background variables with the cognitive level among patients recovered from cerebrovascular accident (N=30). S. No. Background variables Normal Mild cognitive impairment Significant cognitive impairment χ 2 and p value No. % No. % No. % 1. 1. Age in years a. 36-45 b. 46-55 c. 56-65 d. 66-75 01 06 02 03.33 20.00 06.67 02 12 07 06.67 40.00 23.33 00 00 00 00 00 00 5.1 0.05* 2. 2. Gender a. Male b. Female 08 01 26.67 03.33 12 09 40.00 30.00 00 00 00 00 2.84 0.032* 3 Family history of cerebrovascular accident a. Yes b. No 05 04 16.67 13.33 01 20 03.33 66.67 00 00 00 00 6.30 0.632 4 Previous history of hospitalization a. Yes b. No 04 03 13.33 10.00 04 19 13.33 63.34 00 00 00 00 4.36 0.613 5 Co-morbid illness a. Yes b. No c. If yes specify: i. Hypertension ii. Diabetes mellitus iii. Hypertension and Diabetes mellitus 04 05 03 00 01 13.33 16.67 10.00 00 03.33 16 05 07 02 07 53.33 16.67 23.33 06.67 23.33 00 00 00 00 00 00 00 00 00 00 2.84 0.024* DISCUSSION The present study showed that 70% of patients had mild cognitive impairment at the time of discharge, 30% of patients had normal cognitive ability at the time of discharge and none of them had significant cognitive impairment. There is a statistically significant association between patients’ cognitive level at the time of discharge and selected background such as age, gender and co- morbid illness. There is no significant association between other background variables such as family history of cerebrovascular accident and previous history of hospitalization, and patient’s cognitive level at the time of discharge.
  • 5. Vyshnavi P.V, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(4) 2014 [273-277] www.ijrpp.com ~ 277~ The findings of this study is supported by the study conducted by Sanjiv K Saxena (2006), the study revealed that increasing age is one of significant determinant of cognitive impairment among stroke patients [5]. It is recommended to conduct the study by comparing the cognitive impairment at frequent interval from admission till discharge; the cognitive level of the patients can be associated previous history of stroke. CONCLUSION The study concludes that the level of cognitive impairment is increased with advanced age, male gender and with the presence of co-morbid illness. Nurses should consider these factors and tailor-made the interventions and home care teaching to ensure quality patient care. ACKNOWLEDGEMENT With deep sense of gratitude I express my special thanks to the Managing Trustee, SRU, Prof. P.V. Ramachandran, M.Sc.(N)., chairman, Nursing Education, Dr.B.Sreelekha, Reader, Dept. of Medical Surgical Nursing and Faculty members for their support and guidance. I am grateful to all the patients for their participation and cooperation throughout the period of study. REFERENCES [1] Dalal P, Bhattacharjee M, Vairale J and Bhat P, UN millennium development goals: can we halt the stroke epidemic in India? Annals of Indian Academy of Neurology, 10, 2007, 130-6. [2] Ferri CP, Acosta D, Guerra M, Huang Y and Llibre-Rodriguez JJ, Socioeconomic Factors and All Cause and Cause-Specific Mortality among Older People in Latin America, India, and China: A Population-Based Cohort Study. PLoS Med ,2012 9(2): e1001179. [3] Maya Danovsk, Boyoko Stamenov, Margartia Alexander. Post stroke cognitive impairment- phenomenological and prognostic factors. Journal of IMAB. 2012.18(3)290-297 [4] Murray J, Young J and Forster A , Developing a primary care-based stroke model: the prevalence of longer-term problems experienced by patients and carers, British Journal of General Practice, 2003, 53, 803-807. [5] Saxena, S K. (2006). Prevalence and Correlates of Cognitive Impairment in Stroke Patients in a rehabilitation Setting. International Journal of Psychosocial Rehabilitation. 10 (2) 37-47. [6] Young J, Froster A. Review of stroke rehabilitation. British Medical Journal 2007, 334:86-90.