Therapeutic hypothermia has been advocated for neuroprotection in cardiac arrest-induced encephalopathy, neonatal hypoxic-ischemic encephalopathy, traumatic brain injury, stroke, hepatic encephalopathy, and spinal cord injury, and as an adjunct to certain surgical procedures. In this review, we address physiological mechanism of hypothermia to mitigate neurological injury, the trials that have been performed for each of these indications, the strength of the evidence to support treatment with mild/moderate hypothermia.

1. Global Journal of
Anesthesiology
ISSN: 2455-3476
Peertechz Journals

2. Review Article
Therapeutic Hypothermia
 Authors:Padmaja Durga
 Corresponding author: Padmaja Durga, Professor, [Cardiac and Neuroanesthesia],
Department of Anesthesiology and Intensive Care, Nizam’s Institute of Medical
Sciences, Hyderabad-500082, India, Tel: 090-9440387299
 Dates: Received: 06 October, 2014; Accepted: 29 August, 2015;Published:
01September, 2015
 Citation: Durga P (2015) Therapeutic Hypothermia. Glob J Anesthesiol 2(2): 025-025.


3. Abstract
Therapeutic hypothermia has been advocated for neuroprotection in cardiac arrest-
induced encephalopathy, neonatal hypoxic-ischemic encephalopathy, traumatic brain
injury, stroke, hepatic encephalopathy, and spinal cord injury, and as an adjunct to
certain surgical procedures. In this review, we address physiological mechanism of
hypothermia to mitigate neurological injury, the trials that have been performed for
each of these indications, the strength of the evidence to support treatment with
mild/moderate hypothermia.

4. Thank you
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