Background: Newcastle disease virus (NDV) genotype VII has become the dominant genotype in China. However, NDV genotype II was used to make current commercial NDV vaccines. The mismatch of genotypes between circulating and vaccine strains of viruses may compromise the efficacy of vaccines.

1. Journal of Vaccines and
Immunology
Peertechz Journals

2. Research Article
Efficacy of a Recombinant Genotype VII Vaccine
against Challenge with Velogenic Newcastle
Disease Virus
 Yi Cheng1#, Dongbei Sheng1#, Xiangdong Li1#, Sumei Hong1 , Lixia
Guo1 , Shasha Zhao1 , Yue Yuan1 , Jingjing Xue1 , Hui Tian1, Yipin
Ren1 , Wujie Liu1 * and Kegong Tian1,2*
 *Corresponding author: Wujie Liu, National Research Center for
Veterinary Medicine, Cuiwei Road, High-Tech District, Luoyang, China
471003,
 Kegong Tian, College of Animal Science and Veterinary Medicine, Henan
Agricultural University, Zhengzhou, China, Tel: + (86) 10-59198895; Fax:
+ (86) 10-59198899.
 Dates: Received: 18 October, 2016; Accepted: 24 October, 2016;
Published: 25 October, 2016
 Citation: Cheng Y, Sheng D, Li X, Hong S, Guo L, et al. (2016) Efficacy of
a Recombinant Genotype VII Vaccine against Challenge with Velogenic
Newcastle Disease Virus. J Vaccines Immun 2(1): 019-022.

3. Abstract
Background: Newcastle disease virus (NDV)
genotype VII has become the dominant genotype
in China. However, NDV genotype II was used to
make current commercial NDV vaccines. The
mismatch of genotypes between circulating and
vaccine strains of viruses may compromise the
efficacy of vaccines.

4. Thank you
For more information Read Online Article…
http://www.peertechz.com/Vaccines-Immunology/JVI-1-116.pdf
For
Full
Article
PDF