5. Repeated
haemoptysis
Investigation Haemoptysis from
trauma
Common
associated chest
symptoms
ā¢ Carcinoma
ā¢ Bronchiectasis
ā¢ Carcinoid
tumours
ā¢ Some infections
ā¢ Severe mitral
stenosis (rare)
ā¢ Chest
radiography
ā¢ Bronchoscopy
ā¢ Lung contusion
ā¢ Injury to a major
airway.
ā¢ Treatment
depends on the
underlying
cause.
ā¢ Cough with or
without sputum
ā¢ Pain
ā¢ Breathlessness
ā¢ Hoarseness
ā¢ Fatigue
ā¢ Loss of weight
ā¢ Palpitation (atrial
ļ¬brillation)
10. Flexible Bronchoscopy
ā¢ Performed with the patient awake
ā¢ Oropharynx anaesthetised with topical lignocaine
ā¢ The bronchoscope is passed into the nose or mouth and
through the vocal folds under direct vision.
ā¢ Scope is ļ¬exible, its tip can be directed into the
segmental bronchi with ease.
ā¢ Tissue and sputum samples may be obtained for
diagnostic purposes.
ā¢ Greater range of movement
ā¢ Biopsies are
ā Relatively small and suction limited
11. Rigid Bronchoscopy
ā¢ General anaesthesia required.
ā¢ Ideal for therapeutic manoeuvres
ā Removal of foreign bodies
ā Aspiration of blood and thick secretions
ā Intraluminal surgery
ā¢ Essential
ā Continuous electrocardiography (ECG) and pulse
oximetry monitoring
12. Technique
ā¢ Operator standing behind the patient and lifting the maxilla by the upper
teeth, using the middle ļ¬nger and foreļ¬nger of the left hand.
ā¢ The bronchoscope rests on the left thumb as it is introduced over the
tongue in the midline.
ā¢ Care must be taken not to trap the lips or tongue between the teeth and
the bronchoscope, and the fulcrum should be the left thumb and not the
teeth.
ā¢ The bronchoscope is passed under direct vision into the oropharynx,
behind the epiglottis, until the vocal folds are seen.
ā¢ Turning the instrument through 90Ā° will help to negotiate the vocal folds,
only then should the neck be extended.
ā¢ The tracheal rings and the carina should be easily seen.
ā¢ Advancing the bronchoscope into the right and left main bronchus reveals
the oriļ¬ces of the more peripheral bronchi.
ā¢ Operability of an endobronchial tumour may be assessed in terms of its
location
15. Other techniques of biopsy of
intrathoracic lesions
ā¢ Options
ā Percutaneous needle biopsy under radiological control
ā Endobronchial ultrasound
ā Open-lung biopsy
ā¢ Necessary to
ā Conļ¬rm diagnosis
ā Stage disease
ā Plan treatment
ļ¼ To reduce the requirement for
invasive assessment
ļ¼ Use of high-quality, contrast-
enhanced, multi-slice helical
CT scanning
17. TRACHEAL OBSTRUCTION
ā¢ Present acutely as a life-threatening
emergency
ā¢ Little symptoms until critical narrowing and
stridor occur
18. Treatment
ā¢ Depends on cause.
Tracheostomy Tracheal replacement
with artiļ¬cial
substitutes
Sleeve resections of
the major bronchi
ā¢ To overcome the
obstruction
ā¢ Unsuccessful
ā¢ But resection of up
to 6 cm of trachea
is now possible
ā¢ Also possible
19. 3. INHALED FOREIGN BODIES
ā¢ Common in small children
ā¢ Marked by a choking incident that then apparently passes.
ā¢ Large objects can be inhaled and become lodged in the
wider calibre and more vertically placed right main
bronchus.
ā¢ Possible presentations:
ā Asymptomatic
ā Wheezing, persistent cough and signs of obstructive
emphysema
ā Pyrexia, productive cough
ā¢ Chest x-ray is vital
ā¢ Experienced anaesthetist is required.
ā¢ The procedure may be very difļ¬cult if there is a severe
inļ¬ammatory reaction.
21. PRIMARY LUNG CANCER
ā¢ Most common cancers throughout the world.
ā¢ Surgical resection
ā Limited role in curative treatment
ā Many cases are locally advanced or widely
disseminated and are beyond surgical cure.
ā¢ Thoracic surgeon (in a cancer team) role
ā Diagnosis, staging and palliation apart from resection
in appropriate cases.
ā¢ Risk factor
ā Cigarette smoking (85ā95 per cent of all cases)
ā Atmospheric pollution and certain occupations
22. RISK IS RELATED TO THE LIFETIME
BURDEN OF CIGARETTE SMOKING
ā¢ Commonly quoted as āpack-yearā
ā¢ A āpackā being 20 cigarettes
ā The number of packs smoked per day multiplied
by the number of years of exposure.
23. PATHOLOGICAL TYPES
(RATIO OF ABOUT 1:4)
Small cell
(also known as oat cell)
Pattern of disease,
prognosis, results of
treatment for small cell
carcinoma differ from other
Managed differently based
on the histological
classiļ¬cation.
Non-small cell lung cancer
(NSCLC)
Pathological staging is
critical to treatment and
outcome.
Subdivisions of NSCLC
according to histological
characteristic less important
24. HISTOLOGICAL CLASSIFICATION OF
LUNG CANCER
1. Small cell lung cancers
2. Adenocarcinoma
3. Squamous carcinoma
4. Large cell undiffrentiated
5. Bronchioalveolar carcinoma
25. 1. SMALL CELL LUNG CANCERS
ā¢ Known as oat cell cancers
ā¢ Packed nature of small dense cells.
ā¢ 20 per cent of all lung cancer.
ā¢ Tend to metastasise early to lymph nodes and
by blood-borne spread.
ā¢ The median survival = months.
ā¢ Very responsive to chemotherapy
ā¢ Rarely
ā Cured
ā Surgery needed
26. 2. ADENOCARCINOMA
ā¢ Most common of the NSCLC types
ā¢ Overtake squamous cell carcinoma
ā¢ Increasing incidence
ā Due to an increasing incidence in women and
ā Lower-tar cigarettes that are inhaled more deeply
to get the same effect.
28. 4. LARGE CELL UNDIFFERENTIATED
ā¢ Discrete histological type of NSCLC
ā¢ Included within neuroendocrine tumours.
29. 5. BRONCHIOALVEOLAR CARCINOMA
ā¢ Distinct pattern of growth following the pre-
existing pulmonary architecture
ā¢ Less dense
ā¢ Appears as a patchy diffuse shadow (āground
glassā) on the radiograph
ā¢ After resection, it can appear in another lobe
or the other side.
30. CLINICAL FEATURES
ā¢ Depend on
1. The site of the lesion
2. The invasion of neigh-bouring structures
3. The extent of metastases.
31. COMMON SYMPTOMS
ā¢ Persistance cough, weight loss, dyspnoea and non-speciļ¬c chest pain
ā¢ Haemoptysis
ā¢ Cough, or a changed cough
ā¢ Severe localised pain (intercostal nerve, brachial plexus, leading to
pancoastās syndrome)
ā¢ Dyspnoea
ā¢ Pleural effusion
ā¢ Clubbing and hypertrophic pulmonary osteoarthropathy
ā¢ Invasion of the mediastinum may result
ā Hoarseness
ā Dysphagia
ā Superior vena caval obstruction.
ā¢ Myopathies
ā Eatonālambert syndrome
32. TREATMENT OF LUNG CANCER
ā¢ The internationally agreed tumourānodeā
metastasis (TNM) staging system
ā¢ Tumours graded up to T3, N1, M0
ā Within an anatomical surgical resection
ā Improved prognosis when treated surgically
ā¢ A non-tumour factors
ā General ļ¬tness
ā Lung function tests
ā¢ Incurable disease
ā Palliative
33. SURVIVAL
ā¢ Carcinoma of the bronchus
ā Low survival rate
ā¢ Factors determining prognosis
1. Histological type of the tumour
2. The spread (stage)
3. General condition of the patient.
37. 1. CHEST X-RAY
ā¢ Detect most lung cancers
ā¢ Early curable tumours, are hidden by other
structures.
ā¢ Secondary effects
ā Pleural effusion
ā Distal collapse
ā Raised hemidiaphragm
38. 2. COMPUTED TOMOGRAPHY
ā¢ ļ¬rst investigation in suspected lung cancer
ā¢ To know
ā Primary is resectable (T stage)
ā Any lymph nodes are involved (N stage).
ā Any remote distant metastases (M stage)
39. Lymph node
ā¢ Size more than 2 cm are involved in the disease
(70 per cent)
ā¢ Size less than 10 mm are unlikely to be involved.
ā¢ Presence of cancer in the nodes, need to do
ā Positron emission tomography with radiolabelled
ļ¬uorodeoxy-glucose (fdg-pet) or
ā Biopsy
40. 3. POSITRON EMISSION TOMOGRAPHY
ā¢ Radiolabelled FDG, taken up by all metabolising
cells but more avidly by cancer cells.
ā¢ The FDG enters the krebās cycle but cannot
complete it and accumulates in proportion to the
glucose avidity of the cells.
ā¢ High accumulation is associated with lung cancers
and secondaries.
ā¢ Fdg avid
ā Infection
ā Inļ¬ammation
ā Lymphadenopathy secondary to it
43. 1. BRONCHOSCOPY
ā¢ Usually use a ļ¬exible bronchoscopy
ā¢ Under sedation
ā¢ In centrally placed lung cancers
ā¢ Allows
ā Assessment of the segmental airway,
ā Cytological testing
ā Transbronchial needle aspiration (tbna).
44. 2. ENDOBRONCHIAL ULTRASOUND
ā¢ Assessment of suspicious mediastinal lymph
ā¢ To aid TBNA
ā¢ Endos-copic ultrasound
ā Passing down the oesophagus
ā Allows ļ¬ne needle aspiration (FNA)
ā Less approachable mediastinal lymph nodes
45.
46. 3. COMPUTED TOMOGRAPHY-GUIDED
BIOPSY
ā¢ Good yield of cells for cytological examination.
ā¢ Core of tissue obtained for formal histology.
ā¢ Best for larger and more peripheral lesions.
ā¢ Pneumothorax is common (30 per cent), but
rarely requires intercostal tube drainage.
ā¢ Contraindications include poor respiratory
reserve
47. 4. SURGICAL DIAGNOSIS AND STAGING
1. Mediastinoscopy
2. Mediastinotomy
3. VATS or thoracotomy lymph node/lung
biopsy
48. Cont.
ā¢ To establishing a tissue diagnosis and
assessing the degree of spread
ā¢ Determines resectability.
ā¢ Histological status of mediastinal nodes
ā To avoid unnecessary thoracotomy for incurable
cancers
ā To not deny surgery to patients whose lymph
nodes are enlarged but benign
49. A) Mediastinoscopy
1. Performed under general anaesthesia
2. Patient supine
3. His or her neck extended
4. A transverse incision is made 2 cm above the sternal notch and
deepened until the strap muscles are reached.
5. These are retracted laterally
6. Thyroid isthmus is retracted superiorly to reveal the pretracheal
fascia.
7. Careful blunt dissection in this plane allows access to the
paratracheal and subcarinal nodes.
8. A mediastinoscope is introduced for direct visualisation and
biopsy.
9. Great caution should be used in the presence of superior vena
caval obstruction.
10. Complications include pneumothorax and haemorrhage
50.
51. B) Mediastinotomy
1. An incision is made through the second
intercostal space to gain access to some of the
mediastinal lymph nodes on the affected side.
2. On the left, this includes lymph nodes in the
para-aortic or sub-aortic fossa.
3. Damage to the internal mammary artery and
the phrenic nerve must be avoided.
4. Mediastinal extension of tumour can also be
assessed
52.
53. Cont.
ā¢ These techniques may also be used in the
diagnosis of other mediastinal conditions,
including:
ā Lymphoma
ā anterior mediastinal tumours
ā Thymoma
ā Sarcoid
ā tuberculosis
ā or any other cause of lymphadenopathy
54. C) VATS Mediastinal Lymph Node and
Lung Biopsy
1. For inaccessible mediastinal lymph nodes
2. For diagnosis of the lung tumour has not
been possible through radiological or
bronchoscopic techniques
ā¢ Performed through two or three ports
ā¢ Allows diagnosis of the tumour, staging of the
mediastinum
ā¢ Gives the opportunity to assess the likely
operability of the lung cancer.
55.
56. SURGICAL APPROACH TO LUNG
CANCER RESECTION
1. Thoracotomy
2. Emergency thoracotomy
3. Video-assisted thoracoscopic
surgery
57. 1. THORACOTOMY
ā¢ Standard route into the thoracic cavity
ā A posterolateral thoracotomy.
ā¢ Access to the
ā Lung and major bronchi
ā Pleura
ā Thoracic aorta
ā Oesophagus
ā Posterior mediastinum.
ā¢ A double-lumen endotracheal tube used
ā To allow ventilation of one lung while the other is collapsed
ā To facilitate surgery
ā To protect the non-operated lung
ā To retain control of ventilation
58. Techniques
1. The patient is turned to the lateral position with the affected side
up
2. The lower leg is ļ¬exed at the hip and the knee, with a pillow
between the legs.
3. Table supports are used to maintain the position and additional
strapping is used at the hips for stability.
4. The patientās hips are placed below the break point of the
operating table to allow opening of the intercostal spaces as the
table is angulated.
5. The upper arm may be supported by a bracket in a position of 90Ā°
ļ¬exion.
6. The lower arm is ļ¬exed and positioned by the head.
7. It is important for both the surgeon and the anaesthetist to be
completely satisļ¬ed with the position of the patient and the tube
and lines at this stage
59.
60. Cont.
1. The incision passes 1ā2 cm below the tip of the scapula, and extends posteriorly
and superiorly between the medial border of the scapula and the spine.
2. The incision is deepened through the subcutaneous tissues to the latissimus
dorsi.
3. This muscle is divided with coagulating diathermy, taking care over haemostasis.
4. A plane of dissection is developed by hand deep to the scapula and serratus
anterior.
5. The ribs can be counted down from the highest palpable rib (which is usually the
second) and the sixth rib periosteum is scored with the diathermy near its upper
border.
6. A periosteal elevator is used to lift the periosteum off the superior border of the
rib or alternatively the intercostal muscle is cut with diathermy just above the rib
7. This reveals the pleura, which may be entered by blunt dissection. A rib spreader
is inserted between the ribs and opened gently to prevent fracture.
8. Exposure may be facilitated by dividing the rib at the costal angle or by dividing
the costotransverse ligament.
9. Resection of a rib is not usually required.
10. The anaesthetist is now able to deļ¬ate the affected lung to allow a better view of
the intrathoracic structures.
61.
62. 2. EMERGENCY THORACOTOMY
ā¢ For penetrating wounds of the heart
ā¢ More anterior approach
ā¢ No specialised supporting equipment is required
ā¢ Incision is taken down to the fourth or ļ¬fth rib with a
scalpel, using scissors the pleural cavity opened.
ā¢ Rapid access to the left pleural cavity in cases of
massive left haemothorax and the pericardium if
cardiac tamponade is supected.
ā¢ Left anterior thoracotomy can be quickly converted to
a clamshell or bilateral thoracotomy if necessary
63. FOLLOWING THE OPERATION
ā¢ 24ā28 fr chest drain/s are placed,
ā Seventh or eighth intercostal space
ā Anterior to the mid-axillary line
ā¢ Thoracotomy is closed using paracostal sutures placed around the rib
above and below to reapproximate the ribs or alternatively
intercostal muscle is sutured to the intercostal muscle below the
stripped rib with a continuous absorbable suture.
ā¢ The fascia and muscle layer are closed in layers using an absorbable
suture.
ā¢ Skin closure is a matter of personal preference.
ā¢ Analgesia
ā Started prior to thoracotomy with an epidural catheter or
ā Intraoperatively by inļ¬ltrating the intercostal nerves in the region of the
incision
64.
65. 3. VIDEO-ASSISTED THORACOSCOPIC
SURGERY
ā¢ To gain access to the chest cavity and facilitate
lung resection.
ā¢ Technique
ā Avoids rib-spreading
ā Reduce postoperative pain, length of stay
ā Aids a speedier recovery
68. INTRODUCTION
ā¢ Principle
ā To remove all cancer
ā But to conserve as much lung as possible.
ā¢ Selection of patients
ā Stage of lung cancer
ā Ftness for surgery
ā¢ Surgery with curative intent
ā In early stage lung cancer (T1ā3, N0ā1)
ā¢ Assessment of a patientās (risk scores)
ā Thorascore, cardiovascular function and lung function
ā¢ Selecting the type of procedure (dyspnea)
ā Lung function will aid
69.
70.
71. CHOICE OF LUNG RESECTION
1. Segmentectomy and wedge resection
2. Lobectomy
3. Pneumonectomy
72.
73. A) Segmentectomy and Wedge
Resection
ā¢ Performed small tumours and with borderline
ļ¬tness
ā¢ Via thoracotomy or VATS.
ā¢ Segmentectomy
ā Anatomical dissection
ā Ligation of the segmental pulmonary artery, vein and
bronchus
ā¢ Wedge resection combined with removal of
regional lymph nodes.
ā Non-anatomical excision
74. B) Lobectomy
ā¢ In early stage lung cancer.
ā¢ Via thoracotomy or vats.
1. Dissection of the ļ¬ssure and hilar structures,
2. Isolated and ligated the branches of the pulmonary artery and
veins to the lobe
3. The bronchus is usually stapled but can be sewn.
4. At the end of the operation, the remaining lung is reinļ¬ated.
ā¢ Some air leak is common and usually settles within a few days.
ā¢ One or two intercostal drains are inserted.
ā¢ The patient does not routinely need intensive care and
postoperative ventilation is best avoided.
ā¢ The average length of stay is around 5ā7 days.
75. C) Pneumonectomy
ā¢ Removal of a whole lung
ā¢ Higher mortality rate
ā¢ Patient must fit for procedure
ā¢ Reserved for centrally placed tumours involving the
main bronchus or those that straddle the ļ¬ssure.
ā¢ At thoracotomy, do an inspection of the lung and
direct palpation of the mass
1. Irresectability.
ā Fixation of the tumour to the aorta, heart or oesophagus
2. Poor prognosis
ā Involvement of the mediastinal lymph node chain
76. COMPLICATIONS OF LUNG RESECTION
ā¢ Bleeding.
ā Careful surgical technique
ā Severe in dense adhesions.
ā¢ Respiratory infection.
ā Ex-smokers due to basal collapse and hypoxaemia
postoperatively.
ā¢ Persistent air leak.
ā¢ Bronchopleural ļ¬stula.
77.
78. Bronchopleural ļ¬stula.
ā¢ Serious complication.
ā¢ Has a high morbidity and mortality rate.
ā¢ Unlikely to resolve spontaneously
ā¢ Management is highly specialised.
ā¢ Following pneumonectomy, the space left behind is initially ļ¬lled with air.
ā¢ This is slowly reabsorbed and the space ļ¬lls with tissue ļ¬uid.
ā¢ The ļ¬uid level rises until the air is ļ¬nally reabsorbed.
ā¢ Dehiscence of the bronchial stump leads to the development of a
bronchopleural ļ¬stula and the ļ¬uid in the space is expectorated in large
quantities.
ā¢ Nursed sitting up and turned so that the affected space is dependent, to
prevent infected ļ¬uid from entering the remaining lung
ā¢ Arrangements are made to site a pleural drain.
ā¢ This should be connected to an underwater seal, but not suction.
79. POSTOPERATIVE CARE
A. Following lung resection, limited respiratory reserve
B. Infection and ļ¬uid overload are to be avoided.
1. Remove the drain when air leaks have settled
2. Mobilisation, breathing exercises and regular physiotherapy
3. Postoperative pain - 3 strategies
ā Patient-controlled analgesia (PCA) with intravenous boluses of opiates
ā Paravertebral/extrapleural or epidural catheter-delivered local
anaesthetic
ā Background oral analgesia with paracetamol.
4. Avoidable chronic pain
ā Rib fracture
ā Entrapment of intercostal nerves
81. BENIGN TUMOURS
ā¢ Less than 15 per cent of solitary lesions
ā¢ Seen on chest x-rays.
ā¢ A peripheral tumour
ā No symptoms until it is large
ā¢ A central tumour
ā Haemoptysis and signs of bronchial obstruction while small.
ā¢ Benign
ā Not increased in size on chest x-rays for more than two years
ā It has some degree of calciļ¬cation
ā¢ Benign nodules
ā Granulomas (tuberculosis or histoplasmosis).
ā¢ Most common benign tumour
ā Hamartoma
ā¢ Diagnosis and deļ¬nitive treatment
ā Excision of the lesion.
82. BRONCHOPULMONARY CARCINOID
TUMOURS
ā¢ Carcinoid tumours
ā¢ Currently classiļ¬ed within a spectrum of
neuroendocrine tumours.
ā¢ From the neuroendocrine cells of bronchial
glands.
ā¢ Most found in the major bronchi
ā¢ Characteristically slow growing and highly
vascular.
ā¢ 15 % metastasise.
83. Cont.
ā¢ Presents with a history of recurrent pneumonia
or haemoptysis
ā¢ Carcinoid syndrome is rare
ā¢ Prognosis following complete resection is
excellent
Surgical excision is preferred
1. Segmental or wedge resection = small peripheral
tumour
2. Lobectomy or pneumonectomy = central
tumours.
84. THE CHEST TRAUMA
1. Approaches to trauma
2. Indications for emergency room thoractomy
3. Thoracotomy approaches
4. Early deaths after thoracic trauma
85. APPROACH TO TRAUMA
ā¢ Methodical and exact
ā¢ General principles of resuscitation and ATLS
(advanced trauma and life support) must be
followed.
86. INDICATIONS FOR EMERGENCY ROOM
THORACTOMY IN BLUNT CHEST TRAUMA
1. Massive haemothorax
2. Suspected cardiac tamponade
3. Witnessed cardiac arrest in the resuscitation
area.
87. STANDARD APPROACH
ā¢ Left anterior thoracotomy
ā¢ Penetrating injury is in the right chest
ā Extend the incision to bilateral thoracotomies or a
clam-shell incision.
88. EARLY DEATHS AFTER
THORACIC TRAUMA
1. Hypoxaemia, hypovolaemia and tamponade.
2. Diagnose and treat as early as possible
3. Remain highly suspicious
4. Early consultation is advised.
5. Essential that experienced help is
summoned.
90. TUMOURS OF THE CHEST WALL
ā¢ Any component of the chest wall
ā Bone, cartilage and soft tissue.
ā¢ Treated similarly to those that occur in other
sites
ā¢ Major resection and chest wall reconstruction
are contemplated.
91. CERVICAL RIB
ā¢ Fibrous band
ā¢ From the seventh cervical vertebra
ā¢ Inserting onto the ļ¬rst thoracic rib
ā¢ Variety of symptoms from compression of
ā Subclavian artery
ā Brachial plexus
92.
93. THORACIC OUTLET SYNDROME
ā¢ Compression of lower trunk of the plexus
(mainly T1)
ā Wasting of the interossei
ā Altered sensation in the T1 distribution.
ā¢ Compression of the subclavian artery
ā A post-stenotic dilatation with thrombus and
embolus formation.
94.
95. PECTUS CARINATUM (PIGEON CHEST)
ā¢ During the growth spurt at adolescence
ā¢ Sternum is elevated above the level of the ribs
ā¢ Treatment offered for cosmetic reasons.
ā¢ Surgery is best left until the late teens
ā¢ Surgery involves mobilising the sternum
96. PECTUS EXCAVATUM
ā¢ The sternum is depressed
ā¢ Dish-shaped deformity of the anterior
portions of the ribs on one or both sides.
ā¢ Never a cause of respiratory problems.
ā¢ Repaired to improve cosmetic appearance
ā Open procedure (the ravitch procedure)
ā A minimally invasive technique, the nuss
procedure.