3. • Fig. 46.1 Correct positioning
for mediolateral oblique view.
a = Nipple in profile. b =
Pectoralis muscle visible down
to level of the nipple. c =
Inframammary fold visible. d =
Glandular tissue evenly
compressed and adequately
penetrated.
4. • Fig: 46.2. Positioning for the lateral oblique
view.
5. • Fig: 46.3. Positioning for the Craniocaudal
view.
6. • Fig: 46.4. Positioning for a localized
compression view
12. • Fig. 46.8 (A). A typical fibroadenoma with
homogeneous internal echoes with an ovoid shape
and circumscribed margins. There is posterior
acoustic enhancement.
13. • Fig. 46.8 (B,C) Examples of malignant breast masses
with 'benign' ultrasound characteristics. The medullary
carcinoma in B has a smooth welldefined margin and is
'wider that tall'. The grade 3 invasive ductal carcinoma
in C has marked posterior acoustic enhancement;
however its margins are irregular and microlobulated.
14. • Fig. 46.8 (B,C) Examples of malignant breast masses
with 'benign' ultrasound characteristics. The medullary
carcinoma in B has a smooth welldefined margin and is
'wider that tall'. The grade 3 invasive ductal carcinoma
in C has marked posterior acoustic enhancement;
however its margins are irregular and microlobulated.
15. • Fig. 46.8 (D) A typical 'tall' irregular spiculated
hypoechoic attenuating mass in keeping with a
malignant breast tumour.
16. • Fig. 46.8 (E,F) Two examples of fat necrosis mimicking
malignant lesions. The case in E shows two hypoechoic
areas with irregular outlines. The case in F shows a 'tall'
hypoechoic lesion with posterior acoustic shadowing.
17. • Fig. 46.8 (A). (E,F) Two examples of fat necrosis
mimicking malignant lesions. The case in E shows two
hypoechoic areas with irregular outlines. The case in F
shows a 'tall' hypoechoic lesion with posterior acoustic
shadowing.
18. • Fig. 46.8 (G) An invasive lobular carcinoma
presenting as areas of scattered indeterminate
attenuation. There is also increased
hyperechogenicity of intramammary fat on the
right side.
19. • Fig. 46.8. (H) Inflammatory breast cancer with
secondary signs. Note the loss of the normal glandular
adipose differentiation due to increased
hyperechogenicity of the intramammary fat. Lymphatic
dilation is also apparent under the thickened
subcutaneous layer.
20. • Fig. 46.8. (I) A power Doppler image of an
invasive grade 3 breast cancer. Note the high
density of irregular tortuous and branching
vessels penetrating into the centre of the
tumour.
21. • Fig. 46.9 (A) This image shows a focus of high signal
corresponding to a fleck of microcalcification lying
within an irregular hypoechoic mass with intraductal
dilation. (B) The corresponding power Doppler image
demonstrates associated neoangiogenesis. This
corresponded to a small focus of invasive carcinoma
lying within an area of high-grade ductal carcinoma in
situ.
22.
23. • Fig. 46.11 Spiculate mass (arrow) due to an invasive carcinoma on:
(A) lateral view; (B) localised compression magnification view.
24. • Fig. 46.12 A spiculate mass with
microcalcification due to a complex sclerosing
lesion/radial scar (magnification view).
25. • Fig. 46.13 Ultrasound showing an echo-poor
mass with irregular margins and posterior
acoustic shadowing due to a carcinoma.
26.
27. • Fig. 46.15 Magnification localised compression
view showing an architectural distortion (stellate
lesion) due to a benign complex sclerosing
lesion/radial scar.
28. • Fig. 46.16 (A) Stellate appearance (arrows) due
to summation of overlying stromal shadows. (B)
Repeat film shows that no lesion is present.
29. • Fig. 46.17 Stellate opacity due to a surgical
• scar.
30. • Fig. 46.18 Stellate lesion due to an invasive
tubular carcinoma.
31. Fig. 46.19 Stellate lesion with microcalcification
due to a Grade 1 invasive ductal carcinoma. (A)
Magnification view. (B) Specimen radiograph.
32.
33. • Fig. 46.21 A small soft-tissue density with
irregular margins due to a carcinoma is
present just anterior to the left pectoralis
muscle (arrow).
34. • Fig. 46.22 Lipoma-large circumscribed
radiolucent mass with a thin capsule (arrows)
and coarse calcification.
35. • Fig. 46.23 Oil cyst. A round radiolucent lesion
is present at the site of a previous surgical
excision; clinically a firm lump was present.
36. • Fig. 46.24 Adenolipoma. A large circumscribed
mixed density mass is present (arrows). Clinically
only a soft swelling was present.
37. • Fig. 46.25 Galactocele. A circumscribed mixed
density lesion with a capsule (arrows).
38. • Fig. 46.26 Simple cysts. (A) Multiple
circumscribed low soft-tissue density lesions are
seen in both breasts. (B) Ultrasound shows the
typical features of a simple cyst-a well-defined
anechoic lesion with posterior acoustic
accentuation.
39. Fig. 46.27 Intracystic carcinoma in a male
presenting with a mass. (A) The mammogram
shows a circumscribed soft-tissue-density mass.
(B) Ultrasound shows a lobulated intracystic mass
(arrow) with calcification. Histology-non-invasive
carcinoma.
40. • Fig. 46.28 Intracystic carcinoma. (A) The mammogram
shows a circumscribed soft-tissue mass. (B) Ultrasound
shows internal echoes within a cyst. Needle aspiration-
blood-stained fluid containing malignant cells.
Histology-non-invasive carcinoma.
41. • Fig. 46.29 Fibroadenoma. (A) Mammogram-a
circumscribed soft tissue- density lesion. (B)
Ultrasound-a circumscribed solid low
reflectivity mass with posterior acoustic
shadowing. A focus of calcification is seen.
42. • Fig. 46.30 Fibroadenomas. (A) First screening
mammogram. (B) Second round screening
mammogram. Two circumscribed lobulated
masses are present. The superior lesion shows
progressive coarse calcification.
43. • Fig. 46.31 Fibroadenoma. Growth while on
hormone replacement therapy. (A) First
screening mammogram. (B) Second round
screening mammogram.
44. • Fig. 46.32 Phyllodes tumour-mammogram. A
circumscribed soft-tissue mass with a
lobulated outline.
45. • Fig. 46.33 Mutinous
carcinoma and invasive
ductal carcinoma. (A)
Mammogram shows a
poorly defined spiculate
mass: (1) due to invasive
ductal carcinoma and a
circumscribed soft-tissue
mass; (2) due to a
mucinous carcinoma. (B)
Ultrasound shows a
typical low reflectivity
mass: (1) due to invasive
ductal carcinoma, and a
circumscribed mass with
posterior acoustic
accentuation due to the
mutinous carcinoma (2).
46. • Fig. 46.34 Non-invasive intracystic carcinoma.
Mammogram magnified localised
compression views shows a circumscribed
mass with irregular microcalcification.
47. • Fig. 46.35 Invasive ductal carcinoma. (A) Mammogram a
circum- scribed retroareolar mass with poorly defined
posterior margins. (B) Ultrasound a circumscribed mass
with a homogeneous internal echo l pattern and through
transmission of sound.
48. • Fig. 46.36 Sarcoma. A
round soft-tissue mass
with homogeneous
internal echoes and
normal glandular tissue
anteriorly.
49. • Fig. 46.37 Fibroadenoma-an oval well-
defined low reflectivity lesion with posterior
acoustic accentuation.
50. • Fig. 46.38 Giant fibroadenoma. Ultrasound
shows a well-defined mass with a
homogeneous internal echo pattern and
normal glandular tissue anteriorly.
51.
52.
53.
54.
55. • Fig. 46.43 Keloid. A lobulated soft-tissue
opacity is demonstrated overlying the upper
part of the breast (arrows).
56.
57. • Fig. 46.45 Ductal carcinoma in situ-comedo
type. Transverse section through a duct
showing central necrosis and calcification.
(Courtesy of Dr S. Humphreys.)
58. • Fig. 46.46 Ductal carcinoma in situ-high-grade
comedo type. (A-C) Irregular linear branching
microcalcification.
59. • Fig. 46.7: Ductal carcinoma in situ.
Intermediate/low grade. Magnification view
irregular polymorphic particles of
microcalcification.
61. • Fig. 46.49 Ductal carcinoma in situ. Cribriform
architecture. The particles of calcification are
in the small spaces within the thickened duct
wall. (Courtesy of Dr S. Humphreys.)
62. • Fig. 46.50 Ductal carcinoma in situ. Low-grade,
cribriform architecture. (A) Multiple clusters of
punctate microcalcification distributed throughout
one quadrant. (B, C) Solitary clusters of slightly
pleomorphic microcalcifications.
63. • Fig. 46.51 Well-defined calcifications
associated with secretory change.
66. • Fig. 46.54 Microcystic change. Multiple
rounded calcifications of similar density.
67. • Fig. 46.55 Sclerosing adenosis. (A,B) Clusters
of fine granular pleomorphic calcifications.
(C) The calcifications are coarser and are
associated with a soft tissue opacity.
68. • Fig. 46.56 Milk of calcium in benign cystic
change. On the craniocaudal view the
calcifications appear as round 'smudge' shadows
(A). On the lateral view the calcifications show a
straight upper border, the 'tea cup‘ sign (B).
69. • Fig. 46.57 Skin
calcification. Multiple
small ring-shaped
calcifications.
75. • Fig. 46.63 Oedematous right breast due to
right heart failure.
76. • Fig. 46.64 Ultrasound of a 48-year-old woman
with a palpable left breast mass. The
mammogram did not demonstrate a mass.
Ultrasound shows a solid mass. FNAC - malignant
cells. Final diagnosis - invasive breast carcinoma.
77. • Fig. 46.65 Localised compression magnification
view of a 56-year-old woman with a palpable left
subareolar mass. The standard views showed no
subareolar abnormality. The localised
compression view, however, shows a spiculate
mass (arrows) due to an invasive carcinoma.
78. • Fig. 46.66 Breast MRI: time-signal intensity
curves following IV contrast. In type I,
enhancement continues through the duration of
the study. In type II, there is a plateau, whereas in
type III, signal intensity diminishes (washout).
79. • Fig. 46.67 Sagittal T 1 -weighted gradient-echo images with
fat saturation pre (A) and post (B) intravenous gadolinium-
DTPA. Two malignant masses are demonstrated. Note typical
heterogeneous and rim enhancement of the larger mass and
clear demonstration of involvement of the prepectoral fascia,
pectoralis major muscle and skin by the inferior mass.
80. • Fig. 46.68 Axial T1 -weighted (A) and T2 -weighted (B) i mages in a
patient with bilateral single lumen silicon implants. Note
extracapsular rupture of the right breast implant, with a collection
of silicon lying in the lateral aspect of the breast. There is
intracapsular rupture of the left breast implant, with a classical
linguine sign.
81. • Fig. 46.69 (A) Implant with silicomoma formation. A firm mass was
palpable adjacent to the lateral aspect of the implant. The
craniocaudal view shows a soft-tissue opacity with irregular margins
adjacent to the lateral aspect of the implant. There are several small
round nodules in the adjacent breast tissue. (B) Ultrasound at the site
of the mass shows acoustic shadowing only.
82.
83.
84. • Fig. 46.72 1 4G needle and automated biopsy
device used for ultrasound and stereotactic
core breast biopsy.
85. • Fig. 46.73 Ultrasound-guided 14G core biopsy of a
solid mass. (A) The tip of the needle is positioned
just proximal to the lesion prior to firing the biopsy
device. (B) The needle is demonstrated within the
lesion after firing the biopsy device. Note that the
needle is parallel to the chest wall.
86.
87. • Fig. 46.75 Stereotactic-guided fine needle
aspiration. The check pair of films shows the
tip of the needle positioned within the small
cluster of microcalcification on both views.
88.
89. • Fig. 46.77 Stereotactic core biopsy. Stereo
film pair showing 'post fire‘ position of needle
during biopsy of microcalcification.
90. • Fig. 46.78 (A) Core biopsy specimen
radiograph demonstrating microcalcification
within the core samples. (B) Core biopsy
showing ductal carcinoma in situ with
calcification.
91. • Fig. 46.79 Vacuum-assisted core biopsy. (A)
Probe showing biopsy port with holes leading to
vacuum-producing apparatus. (B) Biopsy probe
and driver unit.
92. Fig. 46.80 Wire localization and surgical excision of a non
palpable carcinoma. (A) The position of a spiculate mass in
the upper part of the left breast is marked with a localizing
wire. (B) Preoperative specimen radiography confirms that
the mass has been excised.
93. • Fig. 46.81 A ductogram showing small filling
defects due to an intraductal carcinoma
(arrows).