In this lecture, Prof. Mohamed Labib Salem, Prof. of Immunology, Faculty of Science, Tanta University, Egypt presents basic information on Nobel Prize, including history, rules, and winners. He also provides a pathway to young researchers to reach Nobel research that can lead to Nobel Prize.
في هذه المحاضرة يقدم ا.د. محمد لبيب سالم أستاذ علم المناعة بكلية العلوم جامعة طنطا بمصر طريق النجاح في البحث العلمي الذي قد يؤدي إلي جائزة نوبل في العلوم.
Science 7 - LAND and SEA BREEZE and its Characteristics
Signaling mechanisms in nobel research pathway by Prof. Mohamed Labib Salem, Faculty of Science, Tanta University, Egypt
1.
2.
3. Signaling Mechanisms in
Nobel Research Pathway
Dr. Mohamed Labib Salem, PhD
Prof. of Immunology, Faculty of Science
Director, Center of Excellence in Cancer Research
Tanta University, Egypt
6. What is Cell Signaling?
• Cell signaling is the process of
cellular communication within the
body driven by cells releasing and
receiving hormones and other
signaling molecules.
• As a process, cell signaling refers to
a vast network of communication
between, and within, each cell of
our body.
• Cell signaling enables coordination
within multicellular organisms.
7. All our life activities
from born to death
are just like
“Cell Signaling”
9. The Nobel Prize
• The Nobel Prize is considered the most
prestigious prize in the world.
• This prize is given in the 7 fields: Physics,
Chemistry, Medicine, Literature, Economics,
and Peace Prize (1901) Economic sciences
(1968).
11. The man: Alfred Nobel (1833–1896)
• The Nobel Prize is the legacy of Sweden’s Nobel. A chemist,
engineer, inventor and entrepreneur.
• Nobel was devoted to the study of explosives, and his
inventions include a blasting cap, dynamite and smokeless
gunpowder.
• When Nobel died, he held 355 patents in different countries
and had made a fortune.
• His last will, signed in 1895, is the reason that the Nobel Prize
is awarded every year.
12. The Nobel Prize
The Nobel Prize is awarded
to ‘those who, during the
preceding year, shall have
conferred the greatest
benefit on mankind’
13. The party on 10 December
• At the Stockholm Concert Hall, the winners in
physics, chemistry, physiology or medicine, literature
and economic sciences receive a medal from the
King of Sweden, as well as a diploma and a cash
award.
• The ceremony is followed by a gala banquet at
Stockholm City Hall.
• The Nobel Peace Prize is awarded in Oslo City Hall on
the same day.
14. The Nobel Prize: The money
• In his last will, Nobel declared that he wanted the bulk of
his assets to go to a fund, and that the interest from that fund
should be distributed as annual prizes.
• Four institutions in Sweden and Norway conferring the prizes
were to be:
The Swedish Academy of Sciences, Karolinska Institute
in Stockholm, the Academy in Stockholm and a
committee of five persons to be elected by the
Norwegian parliament (the Storting).
15. The Nobel Prize: The money
• The recipients of the first Nobel Prizes were
given 150,782 SEK.
• The Nobel Prize sum is currently SEK 10
million (around EUR 950,000) for each prize
category, even when the prize is shared.
• There may be no more than three winners, or
laureates, for each prize category.
16. The Nobel Prize: The Foundation
• In 1900 the four institutions awarding the prizes
agreed to create the Nobel Foundation, a private
institution based on the will of Alfred Nobel.
• The foundation would administer Alfred Nobel’s
assets, totaling more than SEK 31 million (quite
a sum of money at the time), make public
announcements and arrange the prize
ceremonies.
17. The Peace Prize
• Sweden and Norway were still in union
(1814–1905) at the time of Alfred
Nobel’s will.
• Why Nobel wanted the Peace Prize in
particular to be awarded by a
Norwegian committee remains unclear.
18. The gender gap
• The Nobel Prize has been awarded to
57 women between 1901 and 2020.
• 962 prize winners, individuals and organizations.
• One woman, Marie Curie, was honored twice,
receiving the 1903 Nobel Prize in Physics and the
1911 Nobel Prize in Chemistry.
• In 1909, Swede Selma Lagerlöf became the first
female literature laureate.
19. The Nobel Prize: The Age Gap
• The youngest Nobel Prize winner to date is Malala
Yousafzai, who was 17 years old when she was awarded the
Nobel Peace Prize in 2014.
• The oldest prize winner to date is John B. Goodenough, who
was 97 when he was awarded the Prize in Chemistry in 2019.
• Rudyard Kipling is the youngest literature laureate to date.
The Englishman, best known for The Jungle Book, was 41
years old when he was awarded the Literature Prize in 1907.
• The oldest literature laureate is Doris Lessing, who won the
prize in 2007 at the age of 87.
20. The Nobel Prize: The Decliners
• Jean-Paul Sartre, awarded the 1964 Nobel Prize in
Literature, declined the award because he had
consistently declined all official honors.
• Lê Ðức Thọ was awarded the 1973 Nobel Peace Prize
jointly with US Secretary of State Henry Kissinger for
negotiating the Vietnam peace agreement.
• Le Duc Tho said he was not in a position to accept the
Nobel Peace Prize, due to the situation in Vietnam.
33. Peter Doherty recounts his unlikely path to
becoming a Nobel Laureate, revealing how
his non conformist upbringing, sense of being
an outsider, and search for a different
perspective have shaped his life and work.
Beginning with his humble origins in
Australia, Doherty shares his early interests
and describes his award-winning, influential
work with Rolf Zinkernagel on T-cells and the
nature of immune defense. He concludes
with tips on how to win a Nobel Prize,
including advice on being persistent,
generous, and culturally aware.
40. Research Process
INPUTS: Hypothesis, Labs, skills,
Team work, etc..
OUTPUTS: Expected Results
OUTCOMES: Significance
The
Beginner’s
Guide
to
Nobel
Science
Figure 1. The cumulative number of physics, chemistry and medicine Nobel prizes per country. Prizes are attributed to the respective country according to the nationality of the recipients at the time of the announcement, with prizes obtained by more than one recipient accordingly divided. Note that the US population increased from 76 to 327 million during 1901–2017.
Science Nobel prizes per 100 million inhabitants. The historical population data at the time of the announcement were used and the obtained yearly increments were cumulatively added. The data can be modelled (grey lines; see equation (2.1)) by a superposition of a linear growth term and a one-time period of either increased (as for the USA, Germany and France) or reduced productivity (as for the UK), centred, respectively, around 1898, 1909, 1972 and 1995 for Germany, France, the USA and the UK.
Historical Nobel productivity. The average number of fractional science Nobel prizes received per year and per 100 million inhabitants, as given by the derivative [Math Processing Error]γ+αg(1−g)/τmax of the respective analytic models. Compare equation (2.1) and figure 2.