chaper of the course of oral pathology .asnan tanta .

1. Benign mesenchymal
non odontogenic tumers
Collected by mohammed saleh Eltahan
Asnan tanta

2. fibroma
• Definition: It is a benign neoplasm of fibrous connective tissue.
• .Fibroma is the most common tumor of the oral cavity.It may
represent a true neoplasm or it may be a reactive hyperplasia of
fibrous connective tissue.
• Etiology: from repeated trauma or chronic irritation.
• *May develop from pyogenic granuloma.

3. Fibroma

4. Clinically:
Age: 4th to 6th
Site: buccal mucosa>lip>tongue>gingiva
Sex: none
Appearance: painless nodule, Usually sessile but may
be pedunculated,
Smooth surface,
Covered with normal color mucosa or may be
ulcerated surface due to trauma.

6. Leaf- shaped fibroma

7. Histologically:
Nodular mass of fibrous connective tissue, covered by
stratified squamous epithelium.
At first proliferation of fibroblasts are prominent leading to
a cellular lesion thus called “recent fibroma gradually, the
connective tissue becomes more dense and collagenized,
and termed “old fibroma,”.
Treatment: conservative excision, otherwise lasts forever.

9. Lipoma
Benign neoplasm of fat cells.
Clinically:
• Age : middle.-aged.
• Site: the buccal mucosa and buccal vestibule are the common
sites.
• Appearance: very Soft, smooth-surfaced nodular mass, sessile or
pedunculated; it is asymptomatic . yellowish color.

11. Histologically:
Composed of mature fat cells.
The tumor is well-circumscribed
encapsulated, and demonstrate a
thin fibrous capsule.
Lobular arrangement of the cells.
Treatment: conservative surgical
excision (usually do not recur,no
malignant transformation).

12. Hamartomas
Definition:
• A group of developmental conditions that present as tumour- like
masses. They are not neoplastic but true neoplasms sometimes arise
from them.
• A hamartoma is a developmental lesion consisting of normal cells in
normal site but in exaggerated amount simulating a tumor.

13. Nevi
• A nevus is a hamartoma of the skin or mucous
membrane arising from cells native to the tissue and
resembling a neoplasm.
Nevi are classified into:
1) Keratotic nevi: White sponge nevus.
2 )Vascular nevi: Haemangioma and
lymphangioma.
3)Pigmented nevi:
Melanocytic nevus.(Mole ).

14. Haemangioma
Haemangiomas are benign tumors of infancy that are
characterized by rapid growth phase with endothelial
proliferation ,followed by gradual involution.
Clinically:
Age: tumor of infancy ,
occurring in 5-10% of
one- year –old children.
Sex: Females more
than males.

15. Haemangioma

16. Site: The most common location is the head and neck
,which accounts for 60% of cases. Intra- orally it
affects tongue , gingiva and lip.
appear as a swelling, deep red in color usually affecting
lip or tongue; causing macrocheilia or macroglossia.

17. Central (intrabony ) haemangioma
• may occur in the mandible or
maxilla .
• appears in x-ray as a
multilocular radiolucent area.
• It leads to fatal hemorrhage
after extraction of an involved
tooth .
• Slight oozing of blood may
occur when percussion upon
teeth related to the lesion .

19. Lymphangioma
Is a benign
,hamartomatous
tumors of lymphatic
vessels.
Clinically:
Age: at birth
sex: no sex
predilection
Site: marked
predilection for the
head and neck .

20. • Oral lymphangiomas are most frequent on the
anterior two thirds of the tongue ,resulting in
macroglossia.
• Usually ,the tumor is superficial in location and
demonstrates a pebbly surface that resembles a
cluster of translucent vesicles.

21. Histologically:
It consists of many large or
medium- sized or
macroscopic cyst like
structures of dilated
endothelial lined spaces
(lymphatics ) that may be
empty or containing clear
proteinaceous coagulum
and occasional
lymphocytes.

22. Treatment:
• Surgical excision.
• Recurrence is common especially for cavernous lymphangioma of the
oral cavity because of their infiltrative nature.

23. Osteoma
Benign tumors composed of
mature compact or
cancellous bone.
• Osteomas that arise from
the surface of bone are
referred to as periosteal
osteomas, whereas those
that develop centrally
within bone are endosteal
osteomas.

24. Clinically:
• Age: Young adults.
• Site: Mandible > Maxilla, in the mandible: in the
body or the condyle.
• Appearance: Asymptomatic, solitary lesion.
• Periosteal osteomas appear as slowly growing
masses on the surface of the bone.
• X-ray: Osteomas appear as circumscribed radio-
opaque mass.

25. Osteoma of sinus
wall

27. Histopathology
Compact osteomas are composed of normal –
appearing dense bone showing minimal marrow
tissue.
Cancellous osteomas are composed of trabeculae
of cancellous bone and fibro-fatty marrow.

28. Chondroma
• it is a benign tumor composed of mature hyaline cartilage.
• Chondroma is rarely seen in the jaws, especially in comparison with
their occurrence in other skeletal sites.

29. Chondroma

30. Clinically:
• Age: usually arises in third and fourth decades
• Site: thought to arise from vestigial cartilaginous
rests; such rests are located in the anterior maxilla; in
the mandible are present in the body, symphysis,
coronoid process, and condyle.
• Appearance:
Painless slowly growing tumors, Tooth mobility and
root resorption are noted.

31. Chondroma

32. X-ray:
• Irregular radiolucent area with central areas of radiopacity.
• Histologically:
• Well-defined lobules of mature hyaline cartilage.
• The chondrocytes are small and contain single, regular nuclei.
• Treatment: total surgical removal of the tumor.

33. Chondroma

34. It is wise to consider any lesion
diagnosed as chondroma of the jaw to
represent a potential chondrosarcoma.

35. Edit in this data if you want and help others if
you can .
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