What was wrong with Wakefield's study? Discuss at least 1 variable or approach that should have been controlled or assessed. Consider the source of some of his data (parental memory, for example), the small sample size, and whether he considered other variables (genetics, diet, and so on) that could have resulted in symptoms in these children.  Discuss the importance of a control group when using the scientific method. Did Wakefield deserve to be barred from medical practice?  What were the consequences of his inflated conclusions?  References Deer, B. (2011). How the case against the MMR vaccine was fixed. BMJ, 342 . Retrieved from http://www.bmj.com/content/342/bmj.c5347 Schute, N. (2013). Fifteen years after a vaccine scare, a measles epidemic . Retrieved from https://www.npr.org/sections/health-shots/2013/05/21/185801259/fifteen-years-after-a-vaccine-scare-a-measles-epidemic Science Buddies. (2018). Steps of the scientific method: What is the scientific method? Retrieved from https://www.sciencebuddies.org/science-fair-projects/science-fair/steps-of-the-scientific-method#keyinfo Taylor, B., Miller, E., Farrington, C. P., Petropoulos, M. C., Favot-Mayaud, I., Li, J., & Waight, P. A. (1999). Autism and measles, mumps, and rubella vaccine: No epidemiological evidence for a causal association. The Lancet, 353 (9169), 2026-2029. Retrieved from http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(99)01239-8/fulltex Wakefield, A. J., Murch, S. H., Anthony, A., Linnell, J., Casson, D. M., Malik, M., et al. (1998). RETRACTED: Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. The Lancet, 351 . Retrieved from http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(97)11096-0.pdf Ziv, S. (2015). Andrew Wakefield, father of the anti-vaccine movement, responds to the current measles outbreak for the first time. Retrieved from http://www.newsweek.com/2015/02/20/andrew-wakefield-father-anti-vaccine-movement-sticks-his-story-305836.html .

1. What was wrong with Wakefield's study? Discuss at least 1
variable or approach that should have been controlled or
assessed.
Consider the source of some of his data (parental memory, for
example), the small sample size, and whether he considered
other variables (genetics, diet, and so on) that could have
resulted in symptoms in these children.
Discuss the importance of a control group when using the
scientific method.
Did Wakefield deserve to be barred from medical practice?
What were the consequences of his inflated conclusions?
References
Deer, B. (2011). How the case against the MMR vaccine was
fixed.
BMJ, 342
. Retrieved from http://www.bmj.com/content/342/bmj.c5347
Schute, N. (2013).
Fifteen years after a vaccine scare, a measles epidemic
. Retrieved from https://www.npr.org/sections/health-

2. shots/2013/05/21/185801259/fifteen-years-after-a-vaccine-
scare-a-measles-epidemic
Science Buddies. (2018).
Steps of the scientific method: What is the scientific method?
Retrieved from https://www.sciencebuddies.org/science-fair-
projects/science-fair/steps-of-the-scientific-method#keyinfo
Taylor, B., Miller, E., Farrington, C. P., Petropoulos, M. C.,
Favot-Mayaud, I., Li, J., & Waight, P. A. (1999). Autism and
measles, mumps, and rubella vaccine: No epidemiological
evidence for a causal association.
The Lancet, 353
(9169), 2026-2029. Retrieved from
http://www.thelancet.com/journals/lancet/article/PIIS0140-
6736(99)01239-8/fulltex
Wakefield, A. J., Murch, S. H., Anthony, A., Linnell, J.,
Casson, D. M., Malik, M., et al. (1998). RETRACTED: Ileal-
lymphoid-nodular hyperplasia, non-specific colitis, and
pervasive developmental disorder in children.
The Lancet, 351
. Retrieved from
http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-
6736(97)11096-0.pdf
Ziv, S. (2015).
Andrew Wakefield, father of the anti-vaccine movement,
responds to the current measles outbreak for the first time.
Retrieved from http://www.newsweek.com/2015/02/20/andrew-
wakefield-father-anti-vaccine-movement-sticks-his-story-
305836.html